CD-JEV Japanese Encephalitis Vaccine Introduction
Training Modules for Health Care Workers
Module 3
JE vaccine eligibility
Learning objectives
 At the end of the module, the participant will be
able to:
– Describe the recommended immunization schedule for
CD-JEV.
– Describe when a child is eligible for CD-JEV and when
he/she is not eligible.
– Describe the contraindications for vaccination.
 Duration:
– 15 minutes
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Key issues
1 What is the schedule for CD-JEV?
2
What are the contraindications
for vaccination?
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What is the CD-JEV schedule?
 CD-JEV can be given in a single dose from 8 months of
age or older, or to children or adults who intend to enter
endemic areas from non-endemic areas.
JE vaccine
Birth
8 months
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CD-JEV eligibility
 Children 8 months of age or older.
 Adults travelling to endemic areas.
 A child who has received a different JE vaccine in the past
(e.g., mouse brain-derived JE vaccine), even more than
once, can be vaccinated with CD-JEV.
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Can CD-JEV be given at the same time as
other childhood vaccines?
 According to WHO, it is acceptable to give CD-JEV with
other vaccines, such as measles and measles-rubella. No
safety concerns have been identified in co-administration.
 The preferred time to administer CD-JEV to children in JEendemic areas is:
– Close to the earliest recommended age (for maximum protection)
– During other routine immunizations (for ease of administration)
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Precautions and contraindications (1/2)
Mild illness, such as an upper
respiratory tract infection, is
NOT a contraindication. If a
recipient has a mild illness, it is
okay to give them CD-JEV.
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Precautions and contraindications (2/2)
● A very severe adverse reaction or a severe
hypersensitivity reaction (anaphylaxis) to a prior
dose of CD-JEV, or to any vaccine component (e.g.,
gelatin, gentamicin, kanamycin).
● Fever higher than 38.5⁰C. Vaccination should be
postponed and an appointment should be made for
vaccination as soon as possible after the fever settles.
● Immunosuppression (due to disease or medication)
or having the signs and symptoms of AIDS.
● Pregnant and lactating women: If the JE risk is
sufficient to warrant vaccination of pregnant women,
inactivated Vero cell-derived vaccines should be used
preferentially over CD-JEV.
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Key messages
● CD-JEV should be given in a single dose at 8 months
of age or older.
● Vaccination should be postponed when a fever is
higher than 38.5⁰C and not given if there has been a
prior severe hypersensitivity reaction to any vaccine
component.
● It is safe to give CD-JEV to a patient with a mild illness.
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End of module
Thank you for your
attention!
 Next is Module 4: JE vaccine
administration
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