Publications for David James
Publications for David James
2016
Wu, L., Levina, A., Harris, H., Cai, Z., Lai, B.,
Vogt, S., James, D., Lay, P. (2016). Carcinogenic
chromium(VI) compounds formed by
intracellular oxidation of chromium(III) dietary
supplements by adipocytes. Angewandte Chemie
(International Edition), 55(5), 1742-1745. <a
href="http://dx.doi.org/10.1002/anie.201509065"
>[More Information]</a>
Davey, J., Watt, K., Parker, B., Chaudhuri, R.,
Ryall, J., Cunningham, L., Qian, H., Sartorelli,
V., Sandri, M., Chamberlain, J., James, D., et al
(2016). Integrated expression analysis of muscle
hypertrophy identifies Asb2 as a negative
regulator of muscle mass. JCI Insight, 1(5),
e85477. <a
href="http://dx.doi.org/10.1172/jci.insight.85477
">[More Information]</a>
Brandon, A., Stuart, E., Leslie, S., Hoehn, K.,
James, D., Kraegen, E., Turner, N., Cooney, G.
(2016). Minimal impact of age and housing
temperature on the metabolic phenotype of
Acc2K/K mice. Journal of Endocrinology,
228(3), 127-134. <a
href="http://dx.doi.org/10.1530/JOE-15-0444">[
More Information]</a>
Yang, P., Humphrey, S., James, D., Yang, J.,
Jothi, R. (2016). Positive-unlabeled ensemble
learning for kinase substrate prediction from
dynamic phosphoproteomics data.
Bioinformatics, 32(2), 252-259. <a
href="http://dx.doi.org/10.1093/bioinformatics/bt
v550">[More Information]</a>
Rogers, S., Fey, D., McCloy, R., Parker, B.,
Mitchell, N., Payne, R., Daly, R., James, D.,
Caldon, C., Watkins, D., et al (2016). PP1
initiates the dephosphorylation of MASTL,
triggering mitotic exit and bistability in human
cells. Journal of Cell Science, 129(7),
1340-1354. <a
href="http://dx.doi.org/10.1242/jcs.179754">[M
ore Information]</a>
Tonks, K., Coster, A., Christopher, M.,
Chaudhuri, R., Xu, A., Gagnon-Bartsch, J.,
Chisholm, D., James, D., Meikle, P., Greenfield,
J., et al (2016). Skeletal Muscle and Plasma
Lipidomic Signatures of Insulin
Resistance and Overweight/Obesity in Humans.
Obesity, 24(4), 908-916. <a
href="http://dx.doi.org/10.1002/oby.21448">[Mo
re Information]</a>
Parker, B., Thaysen-Andersen, M., Fazakerley,
D., Holliday, M., Packer, N., James, D. (2016).
Terminal Galactosylation and Sialylation
Switching on Membrane Glycoproteins upon
TNF-Alpha-Induced Insulin Resistance in
Adipocytes. Molecular and Cellular Proteomics,
15(1), 141-153. <a
href="http://dx.doi.org/10.1074/mcp.M115.0542
21">[More Information]</a>
Domanova, W., Krycer, J., Chaudhuri, R., Yang,
P., Vafaee, F., Fazakerley, D., Humphrey, S.,
James, D., Kuncic, Z. (2016). Unraveling Kinase
Activation Dynamics Using Kinase-Substrate
Relationships from Temporal Large-Scale
Phosphoproteomics Studies. PloS One, 11(6),
e0157763-Online. <a
href="http://dx.doi.org/10.1371/journal.pone.015
7763">[More Information]</a>
2015
Wong, M., Krycer, J., Burchfield, J., James, D.,
Kuncic, Z. (2015). A generalised enzyme kinetic
model for predicting the behaviour of complex
biochemical systems. FEBS Open Bio, 5,
226-239. <a
href="http://dx.doi.org/10.1016/j.fob.2015.03.00
2">[More Information]</a>
Yang, G., Murashige, D., Humphrey, S., James,
D. (2015). A Positive Feedback Loop between
Akt and mTORC2 via SIN1 Phosphorylation.
Cell Reports, 12(6), 937-943. <a
href="http://dx.doi.org/10.1016/j.celrep.2015.07.
016">[More Information]</a>
Lee, J., Walsh, M., Hoehn, K., James, D.,
Wherry, E., Choi, Y. (2015). Acetyl CoA
Carboxylase 2 Is Dispensable for CD8+ T Cell
Responses. PloS One, 10(9), 1-9. <a
href="http://dx.doi.org/10.1371/journal.pone.013
7776">[More Information]</a>
Kee, A., Yang, L., Lucas, C., Greenberg, M.,
Martel, N., Leong, G., Hughes, W., Cooney, G.,
James, D., Ostap, M., et al (2015). An Actin
Filament Population Defined by the
Tropomyosin Tpm3.1 Regulates Glucose
Uptake. Traffic: the international journal of
intracellular transport, 16(7), 691-711. <a
href="http://dx.doi.org/10.1111/tra.12282">[Mor
e Information]</a>
Ma, X., Lee, P., Chisholm, D., James, D. (2015).
Control of adipocyte differentiation in different
fat depots; Implications for pathophysiology or
therapy. Frontiers in Endocrinology, 6, 1-8. <a
href="http://dx.doi.org/10.3389/fendo.2015.0000
1">[More Information]</a>
Chaudhuri, R., Khoo, P., Tonks, K., Junutula, J.,
Kolumam, G., Modrusan, Z., Samocha-Bonet,
D., Meoli, C., Hocking, S., Fazakerley, D.,
Stockli, J., Yang, J., James, D., et al (2015).
Cross-species gene expression analysis identifies
a novel set of genes implicated in human insulin
sensitivity. Npj Systems Biology And
Applications, 1, 1-10. <a
href="http://dx.doi.org/10.1038/npjsba.2015.10"
Publications for David James
>[More Information]</a>
Rogers, S., McCloy, R., Parker, B., Chaudhuri,
R., Gayevskiy, V., Hoffman, N., Watkins, D.,
Daly, R., James, D., Burgess, A. (2015). Dataset
from the global phosphoproteomic mapping of
early mitotic exit in human cells. Data in Brief,
5, 45-52. <a
href="http://dx.doi.org/10.1016/j.dib.2015.08.01
0">[More Information]</a>
Hoffman, N., Parker, B., Chaudhuri, R.,
Fisher-Wellman, K., Kleinert, M., Humphrey, S.,
Yang, P., Holliday, M., Trefely, S., Fazakerley,
D., Stoeckli, J., Burchfield, J., James, D., et al
(2015). Global Phosphoproteomic Analysis of
Human Skeletal Muscle Reveals a Network of
Exercise-Regulated Kinases and AMPK
Substrates. Cell Metabolism, 22(5), 922-935. <a
href="http://dx.doi.org/10.1016/j.cmet.2015.09.0
01">[More Information]</a>
McCloy, R., Parker, B., Rogers, S., Chaudhuri,
R., Gayevskiy, V., Hoffman, N., Ali, N.,
Watkins, N., Daly, R., James, D., et al (2015).
Global Phosphoproteomic Mapping of Early
Mitotic Exit in Human Cells Identifies Novel
Substrate Dephosphorylation Motifs. Molecular
and Cellular Proteomics, 14(8), 2194-2212. <a
href="http://dx.doi.org/10.1074/mcp.M114.0469
38">[More Information]</a>
Trefely, S., Khoo, P., Krycer, J., Chaudhuri, R.,
Fazakerley, D., Parker, B., Sultani, G., Lee, J.,
Stephan, J., Torres, E., James, D., Stoeckli, J., et
al (2015). Kinome Screen Identifies PFKFB3
and Glucose Metabolism as Important
Regulators of the Insulin/IGF-1 Signalling
Pathway. The Journal of Biological Chemistry,
290(43), 25834-25846. <a
href="http://dx.doi.org/10.1074/jbc.M115.65881
5">[More Information]</a>
Phua, Y., Nguyen, A., Roden, D., Elsworth, B.,
Deng, N., Nikolic, I., Yang, J., McFarland, A.,
Russell, R., Kaplan, W., O'Toole, S., James, D.,
et al (2015). MicroRNA profiling of the pubertal
mouse mammary gland identifies miR-184 as a
candidate breast tumour suppressor gene. Breast
Cancer Research, 17(1), 1-18. <a
href="http://dx.doi.org/10.1186/s13058-015-059
3-0">[More Information]</a>
Chaudhuri, R., Sadrieh, A., Hoffman, N., Parker,
B., Humphrey, S., Stoeckli, J., Hill, A., James,
D., Yang, J. (2015). PhosphOrtholog: a
web-based tool for cross-species mapping of
orthologous protein post-translational
modification. BMC Genomics, 16(1), 1-14. <a
href="http://dx.doi.org/10.1186/s12864-015-182
0-x">[More Information]</a>
Humphrey, S., James, D., Mann, M. (2015).
Protein Phosphorylation: A Major Switch
Mechanism for Metabolic Regulation. Trends in
Endocrinology and Metabolism, 26(12),
676-687. <a
href="http://dx.doi.org/10.1016/j.tem.2015.09.01
3">[More Information]</a>
Fazakerley, D., Naghiloo, S., Chaudhuri, R.,
Koumanov, F., Burchfield, J., Thomas, K.,
Krycer, J., Prior, M., Parker, B., Murrow, B.,
Stoeckli, J., Meoli, C., James, D., et al (2015).
Proteomic Analysis of GLUT4 Storage Vesicles
Reveals Tumour Suppressor Candidate 5
(TUSC5) as a Novel Regulator of Insulin Action
in Adipocytes. The Journal of Biological
Chemistry, 290(39), 23528-23542. <a
href="http://dx.doi.org/10.1074/jbc.M115.65736
1">[More Information]</a>
Tan, S., Fisher_Wellman, K., Fazakerley, D., Ng,
Y., Pant, H., Li, J., Meoli, C., Coster, A.,
Stoeckli, J., James, D. (2015). Selective insulin
resistance in adipocytes. The Journal of
Biological Chemistry, 290(18), 11337-11348. <a
href="http://dx.doi.org/10.1074/jbc.M114.62368
6">[More Information]</a>
Ma, D., Stolte, C., Krycer, J., James, D.,
O'Donoghue, S. (2015). SnapShot: Insulin/IGF1
Signaling. Cell, 161(4), 948-948. <a
href="http://dx.doi.org/10.1016/j.cell.2015.04.04
1">[More Information]</a>
Hocking, S., Stewart, R., Brandon, A., Suryana,
E., Stuart, E., Baldwin, E., Kolumam, G.,
Modrusan, Z., Junutula, J., Gunton, J., James, D.,
et al (2015). Subcutaneous fat transplantation
alleviates diet-induced glucose intolerance and
inflammation in mice. Diabetologia, 58(7),
1587-1600. <a
href="http://dx.doi.org/10.1007/s00125-015-358
3-y">[More Information]</a>
Parker, B., Yang, G., Humphrey, S., Chaudhuri,
R., Ma, X., Peterman, S., James, D. (2015).
Targeted phosphoproteomics of insulin signaling
using data-independent acquisition mass
spectrometry. Science Signaling, 8(380), 1-8. <a
href="http://dx.doi.org/10.1126/scisignal.aaa313
9">[More Information]</a>
Stoeckli, J., Meoli, C., Hoffman, N., Fazakerley,
D., Pant, H., Cleasby, M., Ma, X., Kleinert, M.,
Brandon, A., Lopez, J., James, D., et al (2015).
The RabGAP TBC1D1 Plays a Central Role in
Exercise-Regulated Glucose Metabolism in
Skeletal Muscle. Diabetes, 64(6), 1914-1922. <a
href="http://dx.doi.org/10.2337/db13-1489">[M
ore Information]</a>
2014
Kleinert, M., Sylow Hansen, L., Fazakerley, D.,
Krycer, J., Thomas, K., Oxbøll, A., Jordy, A.,
Jensen, T., Yang, G., Schjerling, P., James, D., et
al (2014). Acute mTOR inhibition induces
insulin resistance
Publications for David James
and alters substrate utilization in vivo. Molecular
Metabolism, 3(6), 630-641. <a
href="http://dx.doi.org/10.1016/j.molmet.2014.0
6.004">[More Information]</a>
Yang, P., Patrick, E., Tan, S., Fazakerley, D.,
Burchfield, J., Gribben, C., Prior, M., James, D.,
Yang, J. (2014). Direction pathway analysis of
large-scale proteomics data reveals novel
features of the insulin action pathway.
Bioinformatics, 30(6), 808-814. <a
href="http://dx.doi.org/10.1093/bioinformatics/bt
t616">[More Information]</a>
Li, J., Cantley, J., Burchfield, J., Meoli, C.,
Stockli, J., Whitworth, P., Pant, H., Chaudhuri,
R., Groffen, A., Verhage, M., James, D. (2014).
DOC2 isoforms play dual roles in insulin
secretion
and insulin-stimulated glucose uptake.
Diabetologia, 57(10), 2173-2182. <a
href="http://dx.doi.org/10.1007/s00125-014-331
2-y">[More Information]</a>
Chow, J., Lawrence, R., Healy, M., Dominy, J.,
Liao, J., Breen, D., Byrne, F., Kenwood, B.,
Lackner, C., et al, James, D. (2014). Genetic
inhibition of hepatic acetyl-CoA carboxylase
activity increases liver fat and alters global
protein acetylation. Molecular Metabolism, 3(4),
419-431. <a
href="http://dx.doi.org/10.1016/j.molmet.2014.0
2.004">[More Information]</a>
Wu, L., Samocha-Bonet, D., Whitworth, P.,
Fazakerley, D., Turner, N., Biden, T., James, D.,
Cantley, J. (2014). Identification of fatty acid
binding protein 4 as
an adipokine that regulates insulin secretion
during obesity. Molecular Metabolism, 3(4),
465-473. <a
href="http://dx.doi.org/10.1016/j.molmet.2014.0
2.005">[More Information]</a>
Ma, X., Yang, P., Kaplan, W., Lee, B., Wu, L.,
Yang, J., Yasunaga, M., Sato, K., Chisholm, D.,
James, D. (2014). ISL1 Regulates Peroxisome
Proliferator-Activated Receptor gamma
Activation and Early Adipogenesis via Bone
Morphogenetic Protein 4-Dependent and
-Independent Mechanisms. Molecular and
Cellular Biology, 34(19), 3607-3617. <a
href="http://dx.doi.org/10.1128/MCB.00583-14"
>[More Information]</a>
Taddeo, E., Laker, R., Breen, D., Akhtar, Y.,
Kenwood, B., Liao, J., Zhang, M., Fazakerley,
D., Tomsig, J., Harris, T., James, D., et al (2014).
Opening of the mitochondrial permeability
transition pore links mitochondrial dysfunction
to insulin resistance in skeletal muscle.
Molecular Metabolism, 3(2), 124-134. <a
href="http://dx.doi.org/10.1016/j.molmet.2013.1
1.003">[More Information]</a>
Lee, J., Walsh, M., Hoehn, K., James, D.,
Wherry, E., Choi, Y. (2014). Regulator of Fatty
Acid metabolism, acetyl coenzyme a carboxylase
1, controls T cell immunity. The Journal of
Immunology, 192(7), 3190-3199. <a
href="http://dx.doi.org/10.4049/jimmunol.13029
85">[More Information]</a>
Parker, B., Shepherd, N., Trefely, S., Hoffman,
N., White, M., Engholm-Keller, K., Hambly, B.,
Larsen, M., James, D., Cordwell, S. (2014).
Structural Basis for Phosphorylation and Lysine
Acetylation Cross-talk in a Kinase Motif
Associated with Myocardial Ischemia and
Cardioprotection. The Journal of Biological
Chemistry, 289(37), 25890-25906. <a
href="http://dx.doi.org/10.1074/jbc.M114.55603
5">[More Information]</a>
Wu, L., Meoli, C., Mangiafico, S., Fazakerley,
D., Cogger, V., Mohamad, M., Pant, H., Kang,
M., Powter, E., Burchfield, J., Gamble, J., Le
Couteur, D., James, D., et al (2014). Systemic
VEGF-A Neutralization Ameliorates
Diet-Induced
Metabolic Dysfunction. Diabetes, 63(8),
2656-2667. <a
href="http://dx.doi.org/10.2337/db13-1665">[M
ore Information]</a>
Fletcher, R., Gribben, C., Ma, X., Burchfield, J.,
Thomas, K., Krycer, J., James, D., Fazakerley,
D. (2014). The Role of the Niemann-Pick
Disease, Type C1 Protein in
Adipocyte Insulin Action. PloS One, 9(4), 1-10.
<a
href="http://dx.doi.org/10.1371/journal.pone.009
5598">[More Information]</a>
2013
Iseli, T., Turner, N., Zeng, X., Cooney, G.,
Kraegen, E., Yao, S., Ye, Y., James, D., Ye, J.
(2013). Activation of AMPK by Bitter Melon
Triterpenoids Involves CaMKKbeta. PloS One,
8(4), 1-9. <a
href="http://dx.doi.org/10.1371/journal.pone.006
2309">[More Information]</a>
Yu, H., Rathore, S., Lopez, J., Davis, E., James,
D., Martin, J., Shen, J. (2013). Comparative
studies of Munc18c and Munc18-1 reveal
conserved and divergent mechanisms of
Sec1/Munc18 proteins. Proceedings of the
National Academy of Sciences of the United
States of America (PNAS), 110(35),
E3271-E3280. <a
href="http://dx.doi.org/10.1073/pnas.131123211
0">[More Information]</a>
Humphrey, S., Yang, G., Yang, P., Fazakerley,
D., Stockli, J., Yang, J., James, D. (2013).
Publications for David James
Dynamic adipocyte phosphoproteome reveals
that akt directly regulates mTORC2. Cell
Metabolism, 17(6), 1009-1020. <a
href="http://dx.doi.org/10.1016/j.cmet.2013.04.0
10">[More Information]</a>
Shewan, A., McCann, R., Lamb, C., Stirrat, L.,
Kioumourtzoglou, D., Adamson, I., Verma, S.,
James, D., Bryant, N. (2013). Endosomal sorting
of GLUT4 and Gap1 is conserved between yeast
and insulin-sensitive cells. Journal of Cell
Science, 126(7), 1576-1582. <a
href="http://dx.doi.org/10.1242/jcs.114371">[M
ore Information]</a>
Tonks, K., Ng, Y., Miller, S., Coster, A.,
Samocha-Bonet, D., Iseli, T., Xu, A., Patrick, E.,
Yang, J., Junutula, J., et al (2013). Impaired Akt
phosphorylation in insulin-resistant human
muscle is accompanied by selective and
heterogeneous downstream defects.
Diabetologia, 56(4), 875-885. <a
href="http://dx.doi.org/10.1007/s00125-012-281
1-y">[More Information]</a>
Burchfield, J., Lu, J., Fazakerley, D., Tan, S.,
Ng, Y., Mele, K., Buckley, M., Han, W.,
Hughes, W., James, D. (2013). Novel systems
for dynamically assessing insulin action in live
cells reveals heterogeneity in the insulin
response. Traffic: the international journal of
intracellular transport, 14(3), 259-273. <a
href="http://dx.doi.org/10.1111/tra.12035">[Mor
e Information]</a>
Xie, L., Yang, Y., Liang, T., Dolai, S., Xie, H.,
Parsaud, L., Lopez, J., He, Y., Chidambaram, S.,
Lam, P., et al (2013). RalA GTPase Tethers
Insulin Granules to L- and R-Type Calcium
Channels Through Binding α2δ-1 Subunit.
Traffic: the international journal of intracellular
transport, 14(4), 428-439. <a
href="http://dx.doi.org/10.1111/tra.12047">[Mor
e Information]</a>
2012
Tan, S., Ng, Y., Meoli, C., Kumar, A., Khoo, P.,
Fazakerley, D., Junutula, J., Vali, S., James, D.,
Stockli, J. (2012). Amplification and
demultiplexing in insulin-regulated Akt protein
kinase pathway in adipocytes. The Journal of
Biological Chemistry, 287(9), 6128-6138. <a
href="http://dx.doi.org/10.1074/jbc.M111.31823
8">[More Information]</a>
Christie, M., Whitten, A., King, G., Hu, S.,
Jarrott, R., Chen, K., Duff, A., Callow, P.,
Collins, B., James, D., et al (2012).
Low-resolution solution structures of Munc 18:
Syntaxin protein complexes indicate an open
binding mode driven by the Syntaxin N-peptide.
Proceedings of the National Academy of
Sciences of the United States of America (PNAS),
109(25), 9816-9821. <a
href="http://dx.doi.org/10.1073/pnas.111697510
9">[More Information]</a>
King, G., Stockli, J., Hu, S., Winnen, B., Duprez,
W., Meoli, C., Junutula, J., Jarrott, R., James, D.,
Whitten, A., et al (2012). Membrane-curvature
protein exhibits interdomain flexibility and binds
a small GTPase. The Journal of Biological
Chemistry, 287(49), 40996-41006. <a
href="http://dx.doi.org/10.1074/jbc.M112.34980
3">[More Information]</a>
Hoehn, K., Turner, N., Cooney, G., James, D.
(2012). Phenotypic Discrepancies in Acetyl-CoA
Carboxylase 2-deficient Mice. Journal of
Biological Chemistry, 287(19), 15801. <a
href="http://dx.doi.org/10.1074/jbc.O112.356915
">[More Information]</a>
Yang, P., Humphrey, S., Fazakerley, D., Prior,
M., Yang, G., James, D., Yang, J. (2012).
Re-Fraction: A machine learning approach for
deterministic identification of protein
homologues and splice variants in large-scale
MS-based proteomics. Journal of Proteome
Research, 11(5), 3035-3045. <a
href="http://dx.doi.org/10.1021/pr300072j">[Mo
re Information]</a>
Davey, J., Humphrey, S., Junutula, J., Mishra,
A., Lambright, D., James, D., Stockli, J. (2012).
TBC1D13 is a RAB35 specific GAP that plays
an important role in GLUT4 trafficking in
adipocytes. Traffic: the international journal of
intracellular transport, 13(10), 1429-1441. <a
href="http://dx.doi.org/10.1111/j.1600-0854.201
2.01397.x">[More Information]</a>
Tan, S., Ng, Y., Burchfield, J., Ramm, G.,
Lambright, D., Stockli, J., James, D. (2012). The
RabGAP TBC1D4/AS160 contains an atypical
PTB domain that interacts with plasma
membrane phospholipids to facilitae GLUT4
trafficking in adipocytes. Molecular and Cellular
Biology, 32(24), 4946-4959. <a
href="http://dx.doi.org/10.1128/MCB.00761-12"
>[More Information]</a>
Hu, S., Whitten, A., King, G., Jones, A.,
Rowland, A., James, D., Martin, J. (2012). The
weak complex between RhoGAP Protein
ARHGAP22 and Signal Regulatory Protein
14-3-3 has 1:2 stoichiometry and a single peptide
binding mode. PloS One, 7(8), 1-11. <a
href="http://dx.doi.org/10.1371/journal.pone.004
1731">[More Information]</a>
Humphrey, S., James, D. (2012). Uncaging Akt.
Science Signaling, 5(223). <a
href="http://dx.doi.org/10.1126/scisignal.200308
5">[More Information]</a>
2011
Stockli, J., Fazakerley, D., James, D. (2011).
GLUT4 exocytosis. Journal of Cell Science,
Publications for David James
124(24), 4147-4159. <a
href="http://dx.doi.org/10.1242/jcs.097063">[M
ore Information]</a>
Rowland, A., Larance, M., Hughes, W., James,
D. (2011). Identification of RhoGAP22 as an
Akt-Dependent Regulator of Cell Motility in
Response to Insulin. Molecular and Cellular
Biology, 31(23), 4789-800. <a
href="http://dx.doi.org/10.1128/MCB.05583-11"
>[More Information]</a>
Rowland, A., Fazakerley, D., James, D. (2011).
Mapping Insulin/GLUT4 Circuitry. Traffic: the
international journal of intracellular transport,
12(6), 672-681. <a
href="http://dx.doi.org/10.1111/j.1600-0854.201
1.01178.x">[More Information]</a>
Tan, S., Ng, Y., James, D. (2011).
Next-generation Akt inhibitors provide greater
specificity: effects on glucose metabolism in
adipocytes. The Biochemical Journal, 435(2),
539-544. <a
href="http://dx.doi.org/10.1042/BJ20110040">[
More Information]</a>
Prior, M., Larance, M., Lawrence, R., Soul, J.,
Humphrey, S., Burchfield, J., Kistler, C., Davey,
J., La-Borde, P., Buckley, M., James, D., et al
(2011). Quantitative Proteomic Analysis of the
Adipocyte Plasma Membrane. Journal of
Proteome Research, 10(11), 4970-4982. <a
href="http://dx.doi.org/10.1021/pr200446r">[Mo
re Information]</a>
Bach, M., Larance, M., James, D., Ramm, G.
(2011). The serine/threonine kinase ULK1 is a
target of multiple phosphorylation events. The
Biochemical Journal, 440(2), 283-291. <a
href="http://dx.doi.org/10.1042/BJ20101894">[
More Information]</a>
href="http://dx.doi.org/10.1016/j.cmet.2009.11.0
08">[More Information]</a>
Tan, S., Ng, Y., James, D. (2010). Akt inhibitors
reduce glucose uptake independently of their
effects on Akt. Biochemical Journal, 432(1),
191-197. <a
href="http://dx.doi.org/10.1042/BJ20100750">[
More Information]</a>
Ng, Y., Ramm, G., Burchfield, J., Coster, A.,
Stockli, J., James, D. (2010). Cluster Analysis of
Insulin Action in Adipocytes Reveals a Key Role
for Akt at the Plasma Membrane. Journal of
Biological Chemistry, 285(4), 2245-2257. <a
href="http://dx.doi.org/10.1074/jbc.M109.06023
6">[More Information]</a>
Ng, Y., Ramm, G., James, D. (2010). Dissecting
the mechanism of insulin resistance using a
novel heterodimerization strategy to activate Akt.
Journal of Biological Chemistry, 285(8),
5232-5239. <a
href="http://dx.doi.org/10.1074/jbc.M109.06063
2">[More Information]</a>
Larance, M., Rowland, A., Hoehn, K.,
Humphreys, D., Preiss, T., Guilhaus, M., James,
D. (2010). Global phosphoproteomics identifies
a major role for AKT and 14-3-3 in regulating
EDC3. Molecular and Cellular Proteomics, 9(4),
682-694. <a
href="http://dx.doi.org/10.1074/mcp.M900435MCP200">[More Information]</a>
Lamb, C., McCann, R., Stockli, J., James, D.,
Bryant, N. (2010). Insulin-Regulated Trafficking
of GLUT4 Requires Ubiquitination. Traffic
(Malden), 11, 1445-54. <a
href="http://dx.doi.org/10.1111/j.1600-0854.201
0.01113.x">[More Information]</a>
Hu, L., Ye, J., Li, J., James, D., Kraegen, E.,
Zhang, H., Cheng, Z., Li, J. (2010). 13,
13a-Dihydroberberine derivatives, their
pharmaceutical compositions and uses. Patent
No. 2007816496.
Hocking, S., Wu, L., Guilhaus, M., Chisholm,
D., James, D. (2010). Intrinsic depot-specific
differences in secretome of adipose tissue,
preadipocytes and adipose tissue derived
microvascular endothelial cells. Diabetes,
59(12), 3008-3016. <a
href="http://dx.doi.org/10.2337/db10-0483">[M
ore Information]</a>
Konstantopoulos, N., Foletta, V., Segal, D.,
Shields, K., Sanigorski, A., Windmill, K.,
Swinton, C., Connor, T., Wanyonyi, S., Dyer, T.,
et al (2010). A Gene Expression Signature for
Insulin Resistance. Physiological Genomics,
43(3), 110-20. <a
href="http://dx.doi.org/10.1152/physiolgenomics
.00115.2010">[More Information]</a>
Fazakerley, D., Holman, G., Marley, A., James,
D., Stockli, J., Coster, A. (2010). Kinetic
evidence for unique regulation of GLUT4
trafficking by insulin and AMP-activated protein
kinase activators in L6 myotubes. Journal of
Biological Chemistry, 285(3), 1653-1660. <a
href="http://dx.doi.org/10.1074/jbc.M109.05118
5">[More Information]</a>
Hoehn, K., Turner, N., Swarbrick, M., Wilks, D.,
Preston, E., Phua, Y., Joshi, H., Furler, S., James,
D., et al (2010). Acute or chronic upregulation of
mitochondrial fatty acid oxidation has no net
effect on whole-body energy expenditure or
adiposity. Cell Metabolism, 11(1), 70-76. <a
Stockli, J., Fazakerley, D., Coster, A., Holman,
G., James, D. (2010). Muscling in on GLUT4
kinetics. Communicative and Integrative
Biology, 3(3), 260-262. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
2010
Publications for David James
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=20714409">[More Information]</a>
2009
Lopez, J., Burchfield, J., Blair, D., Mele, K., Ng,
Y., Vallotton, P., James, D., Hughes, W. (2009).
Identification of a Distal GLUT4 Trafficking
Event Controlled by Actin Polymerisation.
Molecular Biology of the Cell, 20(17),
3918-3929. <a
href="http://dx.doi.org/10.1091/mbc.E09-03-018
7">[More Information]</a>
Stockli, J., James, D. (2009). Insulin Action
under Arrestin. Cell Metabolism, 9(3), 213-214.
<a
href="http://dx.doi.org/10.1016/j.cmet.2009.02.0
05">[More Information]</a>
Hoehn, K., Salmon, A., Hohnen-Behrens, C.,
Turner, N., Hoy, A., Maghzal, G., Stocker, R.,
Van Remmen, H., Kraegen, E., Cooney, G., et al
(2009). Insulin resistance is a cellular antioxidant
defense mechanism. Proceedings of the National
Academy of Sciences of the United States of
America (PNAS), 106(42), 17787-17792. <a
href="http://dx.doi.org/10.1073/pnas.090238010
6">[More Information]</a>
Sun, C., Vallotton, P., Wang, D., Lopez, J., Ng,
Y., James, D. (2009). Membrane boundary
extraction using circular multiple paths. Pattern
Recognition, 42(4), 523-530. <a
href="http://dx.doi.org/10.1016/j.patcog.2008.09.
029">[More Information]</a>
Crowe, S., Wu, L., Economou, C., Turpin, S.,
Matzaris, M., Hoehn, K., Hevener, A., James, D.,
Duh, E., et al (2009). Pigment
epithelium-derived factor contributes to insulin
resistance in obesity. Cell Metabolism, 10(1),
40-47. <a
href="http://dx.doi.org/10.1016/j.cmet.2009.06.0
01">[More Information]</a>
Mele, K., Vallotton, P., Burchfield, J., James, D.,
Hughes, W. (2009). Towards fully automated
identification of Vesicle-Membrane Fusion
Events in TIRF Microscopy. <a
href="http://dx.doi.org/10.1504/IJCAET.2009.02
8555">[More Information]</a>
Ke, C., James, D., Kraegen, E., Cooney, G., Ye,
Y., Tan, M., Chen, T., Li, X., Ye, J. (2009). Use
of compounds extracted from Momordica
charantia L. in the manufacture of medicaments
for prevention and treatment of diabetes and
obesity. Patent No. 2009212026.
Zhao, P., Yang, L., Lopez, J., Fan, J., Burchfield,
J., Bai, L., Hong, W., Xu, T., James, D. (2009).
Variations in the requirement for v-SNAREs in
GLUT4 trafficking in adipocytes. Journal of Cell
Science, 122(19), 3472-3480. <a
href="http://dx.doi.org/10.1242/jcs.047449">[M
ore Information]</a>
2008
Tan, M., Ye, J., Turner, N., Hohnen-Behrens, C.,
Ke, C., Tang, C., Chen, T., Weiss, H., Gesing,
E., Rowland, A., et al (2008). Anti-diabetic
activities of triterpenoids from bitter melon
associated with activation of the AMPK
pathway. Chemistry and Biology, 15(3),
263-273. <a
href="http://dx.doi.org/10.1016/j.chembiol.2008.
01.013">[More Information]</a>
Turner, N., Li, J., Gosby, A., To, S., Cheng, Z.,
Miyoshi, H., Taketo, M., Cooney, G., Kraegen,
E., James, D., et al (2008). Berberine and its
more Biologically Availible Derivative
Dihyroberberine, Inhibit Mitochondrial
Respiratory Complex I: A Mechanism for the
Action of Berberine to Activate AMPK and
Improve Insulin Action. Diabetes, 57(5),
1414-1418. <a
href="http://dx.doi.org/10.2337/db07-1552">[M
ore Information]</a>
Yip, M., Ramm, G., Larance, M., Hoehn, K.,
Wagner, M., Guilhaus, M., James, D. (2008).
CaMKII-Mediated Phosphorylation of the
Myosin Motor Myo1c is required for
Insulin-Stimulated GLUT4 Translocation in
Adipocytes. Cell Metabolism, 8(5), 384-398. <a
href="http://dx.doi.org/10.1016/j.cmet.2008.09.0
11">[More Information]</a>
Govers, R., James, D., Coster, A. (2008).
High-Throughput Analysis of the Dynamics of
Recycling Cell Surface Proteins. In Andrei I.
Ivanov (Eds.), Exocytosis and Endocytosis, (pp.
129-146). New Jersey, United States of America:
Humana Press.
Hoehn, K., Hohnen-Behrens, C., Cederberg, A.,
Wu, L., Turner, N., Yuasa, T., Ebina, Y., James,
D. (2008). IRS1-independent defects define
major nodes of insulin resistance. Cell
Metabolism, 7(5), 421-433. <a
href="http://dx.doi.org/10.1016/j.cmet.2008.04.0
05">[More Information]</a>
Brummer, T., Larance, M., Abreu, M., Lyons,
R., Timpson, P., Emmerich, C., Fleuren, E.,
Lehrbach, G., Schramek, D., Guilhaus, M., et al
(2008). Phosphorylation-dependent binding of
14-3-3 terminates signalling by the Gab2
docking protein. The EMBO Journal, 27(17),
2305-2316. <a
href="http://dx.doi.org/10.1038/emboj.2008.159"
>[More Information]</a>
Ng, Y., Ramm, G., Lopez, J., James, D. (2008).
Rapid Activation of Akt2 is Sufficient to
Stimulate GLUT4 Translocation in 3T3-L1
Adipocytes. Cell Metabolism, 7(4), 348-356. <a
href="http://dx.doi.org/10.1016/j.cmet.2008.02.0
Publications for David James
08">[More Information]</a>
Stockli, J., Davey, J., Hohnen-Behrens, C., Xu,
A., James, D., Ramm, G. (2008). Regulation of
Glut4 Translocation by the RabGAP
AS160/TBC1D4: Role of Phosphorylation and
Membrane Association. Molecular
Endocrinology, 22(12), 2703-2715. <a
href="http://dx.doi.org/10.1210/me.2008-0111">
[More Information]</a>
Achuthan, A., Masendycz, P., Lopez, J., Nguyen,
T., James, D., Sweet, M., Hamilton, J., Scholz,
G. (2008). Regulation of the Endosomal SNARE
Protein Syntaxin 7 by Colony-Stimulating Factor
1 in Macrophages. Molecular and Cellular
Biology, 28(20), 6149-6159. <a
href="http://dx.doi.org/10.1128/MCB.00220-08"
>[More Information]</a>
Bao, Y., Lopez, J., James, D., Hunziker, W.
(2008). Snapin Interacts with the Exo70 subunit
of the exocyst and modulates GLUT4 trafficking.
Journal of Biological Chemistry, 283(1),
324-331. <a
href="http://dx.doi.org/10.1074/jbc.M706873200
">[More Information]</a>
Hocking, S., Chisholm, D., James, D. (2008).
Studies of Regional adipose transplantation
reveal a unique and beneficial interaction
between subcutaneous adipose tissue and the
intra-abdominal compartment. Diabetologia,
51(5), 900-902. <a
href="http://dx.doi.org/10.1007/s00125-008-096
9-0">[More Information]</a>
Larance, M., Ramm, G., James, D. (2008). The
GLUT4 Code. Molecular Endocrinology, 22(2),
226-233. <a
href="http://dx.doi.org/10.1210/me.2007-0282">
[More Information]</a>
Lopez, J., Kwan, E., Xie, L., He, Y., James, D.,
Gaisano, H. (2008). The RalA GTPase is a
Central Regulator of Insulin Exocytosis for
Pancreatic Islet Beta Cells. The Journal of
Biological Chemistry, 283(26), 17939-17945. <a
href="http://dx.doi.org/10.1074/jbc.M800321200
">[More Information]</a>
2007
Hoy, A., Bruce, C., Cederberg, A., Turner, N.,
James, D., Cooney, G., Kraegen, E. (2007).
Glucose infusion causes insulin resistance in
skeletal muscle of rats without changes in Akt
and AS160 phosphorylation. American Journal
of Physiology: Endocrinology and Metabolism,
293(5), e1358-e1364. <a
href="http://dx.doi.org/10.1152/ajpendo.00133.2
007">[More Information]</a>