Publications for Wei Yong Shen Publications for Wei Yong Shen 2016 Xu, C., Zhu, L., Chan, T., Lu, X., Shen, W., Madigan, M., Gillies, M., Zhou, F. (2016). Chloroquine and Hydroxychloroquine Are Novel Inhibitors of Human Organic Anion Transporting Polypeptide 1A2. Journal of Pharmaceutical Sciences, 105(2), 884-890. <a href="http://dx.doi.org/10.1002/jps.24663">[Mor e Information]</a> 2015 Coorey, N., Shen, W., Zhu, L., Gillies, M. (2015). Differential Expression of IL-6/gp130 Cytokines, Jak-STAT Signalling and Neuroprotection After Muller Cell Ablation in a Transgenic Mouse Model. Investigative Ophthalmology & Visual Science, 56(4), 2151-2161. <a href="http://dx.doi.org/10.1167/iovs.14-15695"> [More Information]</a> Zhu, L., Shen, W., Lyons, B., Wang, Y., Zhou, F., Gillies, M. (2015). Dysregulation of inter-photoreceptor retinoid-binding protein (IRBP) after induced Muller cell disruption. Journal of Neurochemistry, 133(6), 909-918. <a href="http://dx.doi.org/10.1111/jnc.13075">[Mo re Information]</a> Burdon, K., Fogarty, R., Shen, W., Abhary, S., Kaidonis, G., Appukuttan, B., Hewitt, A., Sharma, S., Daniell, M., Essex, R., Jenkins, A., Gillies, M., et al (2015). Genome-wide association study for sight-threatening diabetic retinopathy reveals association with genetic variation near the GRB2 gene. Diabetologia, 58(10), 2288-2297. <a href="http://dx.doi.org/10.1007/s00125-015-369 7-2">[More Information]</a> Chung, S., Shen, W., Gillies, M. (2015). Genomic Analysis Using Affymetrix Standard Microarray GeneChips (169 Format) in Degenerate Murine Retina. In Laura Lossi, Adalberto Merighi (Eds.), Neuronal Cell Death: Methods and Protocols, (pp. 129-140). New York: Springer Science+Business Media. <a href="http://dx.doi.org/10.1007/978-1-4939-215 2-2_10">[More Information]</a> Chan, T., Zhu, L., Madigan, M., Wang, K., Shen, W., Gillies, M., Zhou, F. (2015). Human organic anion transporting polypeptide 1A2 (OATP1A2) mediates cellular uptake of all-trans-retinol in human retinal pigmented epithelial cells. British Journal of Pharmacology, 172(9), 2343-2353. <a href="http://dx.doi.org/10.1111/bph.13060">[Mo re Information]</a> Chung, S., Shen, W. (2015). Laser capture microdissection: from its principle to applications in research on neurodegeneration. Neural Regeneration Research, 10(6), 897-898. <a href="http://dx.doi.org/10.4103/1673-5374.1583 46">[More Information]</a> Chung, S., Gillies, M., Sugiyama, Y., Zhu, L., Lee, S., Shen, W. (2015). Profiling of MicroRNAs Involved in Retinal Degeneration Caused by Selective Müller Cell Ablation. PloS One, 10(3), 1-18. <a href="http://dx.doi.org/10.1371/journal.pone.011 8949">[More Information]</a> Xu, C., Zhu, L., Chan, T., Lu, X., Shen, W., Gillies, M., Zhou, F. (2015). The altered renal and hepatic expression of solute carrier transporters (SLCs) in type 1 diabetic mice. PloS One, 10(3), 1-14. <a href="http://dx.doi.org/10.1371/journal.pone.012 0760">[More Information]</a> 2014 Barthelmes, D., Zhu, L., Shen, W., Gillies, M., Irhimeh, M. (2014). Differential gene expression in Lin-/VEGF-R2+ bone marrow-derived endothelial progenitor cells isolated from diabetic mice. Cardiovascular Diabetology, 13(1), 1-10. <a href="http://dx.doi.org/10.1186/1475-2840-13-4 2">[More Information]</a> Shen, W., Lee, S., Araujo, J., Chung, S., Zhu, L., Gillies, M. (2014). Effect of glucocorticoids on neuronal and vascular pathology in a transgenic model of selective Muller cell ablation. Glia, 62(7), 1110-1124. <a href="http://dx.doi.org/10.1002/glia.22666">[Mo re Information]</a> Chung, S., Shen, W., Gillies, M. (2014). Identification of a novel miRNA targeting CD146 for suppression of angiogenesis. Non-coding RNAs Endocrinol, 1, 28-30. <a href="http://dx.doi.org/10.2478/micrnado-2014-0 001">[More Information]</a> Shen, W., Chung, S., Irhimeh, M., Li, S., Lee, S., Gillies, M. (2014). Systemic Administration of Erythropoietin Inhibits Retinopathy in RCS Rats. PloS One, 9(8), e104759. <a href="http://dx.doi.org/10.1371/journal.pone.010 475">[More Information]</a> 2013 Zhu, L., Shen, W., Zhu, M., Coorey, N., Nguyen, A., Barthelmes, D., Gillies, M. (2013). Anti-Retinal Antibodies in Patients With Macular Telangiectasia Type 2. Investigative Ophthalmology and Visual Science, 54(8), 5675-5683. <a href="http://dx.doi.org/10.1167/iovs.13-12050"> [More Information]</a> Publications for Wei Yong Shen Barthelmes, D., Irhimeh, M., Gillies, M., Karimipour, M., Zhou, M., Zhu, L., Shen, W. (2013). Diabetes impairs mobilization of mouse bone marrow-derived Lin-/VEGF-R2+ progenitor cells. Blood Cells, Molecules and Diseases, 51(3), 163-173. <a href="http://dx.doi.org/10.1016/j.bcmd.2013.05. 002">[More Information]</a> Chung, S., Shen, W., Jayawardana, K., Wang, P., Yang, J., Shackel, N., Gillies, M. (2013). Differential gene expression profiling after conditional müller-cell ablation in a novel transgenic model. Investigative Ophthalmology and Visual Science, 54(3), 2142-2152. <a href="http://dx.doi.org/10.1167/iovs.12-1155">[ More Information]</a> Shen, W., Zhu, L., Lee, S., Chung, S., Gillies, M. (2013). Involvement of NT3 and P75NTR in photoreceptor degeneration following selective Muller cell ablation. Journal of Neuroinflammation, 10(137), 1-13. <a href="http://dx.doi.org/10.1186/1742-2094-10-1 37">[More Information]</a> Barthelmes, D., Irhimeh, M., Gillies, M., Zhu, L., Shen, W. (2013). Isolation and characterization of mouse bone marrow-derived Lin−/VEGF-R2+ progenitor cells. Annals of Hematology, 92(11), 1461-1472. <a href="http://dx.doi.org/10.1007/s00277-013-181 5-0">[More Information]</a> Chung, S., Shen, W., Gillies, M. (2013). Laser Capture Microdissection-Directed Profiling of Glycolytic and mTOR Pathways in Areas of Selectively Ablated Muller Cells in the Murine Retina. Investigative Ophthalmology and Visual Science, 54(10), 6578-6584. <a href="http://dx.doi.org/10.1167/iovs.13-12311"> [More Information]</a> 2012 Shen, W., Fruttiger, M., Zhu, L., Chung, S., Barnett, N., Kirk, J., Lee, S., Coorey, N., Killingsworth, M., Sherman, L., Gillies, M. (2012). Conditional Muller Cell Ablation Causes Independent Neuronal and Vascular Pathologies in a Novel Transgenic Model. The Journal of Neuroscience, 32(45), 15715-15727. <a href="http://dx.doi.org/10.1523/JNEUROSCI.28 41-12.2012">[More Information]</a> Coorey, N., Shen, W., Chung, S., Zhu, L., Gillies, M. (2012). The role of glia in retinal vascular disease. Clinical & Experimental Optometry, 95(3), 266-281. <a href="http://dx.doi.org/10.1111/j.1444-0938.201 2.00741.x">[More Information]</a> 2011 Irhimeh, M., Shen, W., Chung, S., Zhu, L., Barthelmes, D., Gillies, M. (2011). Erythropoetin treatment recruits pECFCs from the marrow into the blood and stabilizes retinal vasculature. Experimental Hematology, 39(8), S77-S78. Shen, W., Zhang, J., Chung, S., Hu, Y., Ma, Z., Gillies, M. (2011). Submacular DL-alpha-Aminoadipic Acid Eradicates Primate Photoreceptors but Does Not Affect Luteal Pigment or the Retinal Vasculature. Investigative Ophthalmology and Visual Science, 52(1), 119-127. <a href="http://dx.doi.org/10.1167/iovs.10-6033">[ More Information]</a> Shen, W., Li, S., Chung, S., Zhu, L., Stayt, J., Su, T., Couraud, P., Romero, I., Weksler, B., Gillies, M. (2011). Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium. European Journal of Cell Biology, 90(4), 323-332. <a href="http://dx.doi.org/10.1016/j.ejcb.2010.10.01 3">[More Information]</a> 2010 Shen, W., Li, S., Chung, S., Gillies, M. (2010). Retinal vascular changes after glial disruption in rats. Journal of Neuroscience Research, 88(7), 1485-1499. <a href="http://dx.doi.org/10.1002/jnr.22317">[Mor e Information]</a> 2006 van Eeden, P., Tee, L., Shen, W., Lukehurst, S., Lai, C., Rakoczy, P., Beazley, L., Dunlop, S. (2006). Characterisation of a Model for Retinal Neovascularisation: VEGF model characterisation. Advances in Experimental Medicine and Biology, 572(Retinal Degenerative Diseases), 163-168. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17249570">[More Information]</a> Graham, C., Binz, N., Shen, W., Constable, I., Rakoczy, P. (2006). Laser Photocoagulation: Ocular Research and Therapy in Diabetic Retinopathy. Advances in Experimental Medicine and Biology, 572(Retinal Degenerative Diseases), 195-200. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17249575">[More Information]</a> Binz, N., Graham, C., Simpson, K., Lai, Y., Shen, W., Lai, C., Speed, T., Rakoczy, P. (2006). Long-term effect of therapeutic laser photocoagulation on gene expression in the eye. The F A S E B Journal, 20(2), 383-385. <a Publications for Wei Yong Shen href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=16354724">[More Information]</a> Shen, W., Lai, C., Graham, C., Binz, N., Lai, Y., Eade, J., Guidolin, D., Ribatti, D., Dunlop, S., Rakoczy, P. (2006). Long-term global retinal microvascular changes in a transgenic vascular endothelial growth factor mouse model. Diabetologia, 49(7), 1690-1701. <a href="http://dx.doi.org/10.1007/s00125-006-027 4-8">[More Information]</a> Shen, W., Lai, Y., Lai, C., Binz, N., Beazley, L., Dunlop, S., Rakoczy, P. (2006). Pathological Heterogeneity of Vasoproliferative Retinopathy in Transgenic Mice Overexpressing Vascular Endothelial Growth Factor in Photoreceptors. Advances in Experimental Medicine and Biology. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17249574">[More Information]</a> Sutanto, E., Zhang, D., Lai, Y., Shen, W., Rakoczy, P. (2006). Potential Use of Cellular Promoter(s) to Target RPE in AAV-Mediated Delivery: Cellular promoters and RPE-targeting. Advances in Experimental Medicine and Biology, 572(Retinal Degenerative Diseases), 267-273. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17249583">[More Information]</a> 2005 Kicic, A., Hall, C., Shen, W., Rakoczy, P. (2005). Are stem cell characteristics altered by disease state? Stem Cells and Development, 14(1), 15-28. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=15725741">[More Information]</a> Sutanto, E., Zhang, D., Lai, Y., Shen, W., Rakoczy, P. (2005). Development and Evaluation of the Specificity of a Cathepsin D Proximal Promoter in the Eye. Current Eye Research, 30(1), 53-61. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=15875365">[More Information]</a> Constable, I., Shen, W., Rakoczy, E. (2005). Emerging biological therapies for age-related macula degeneration. Expert Opinion on Biological Therapy, 5(10), 1373-1385. <a href="http://dx.doi.org/10.1517/14712598.5.10.1 373">[More Information]</a> Rodger, J., Symonds, A., Springbett, J., Shen, W., Bartlett, C., Rakoczy, P., Beazley, L., Dunlop, S. (2005). Eph/ephrin expression in the adult rat visual system following localized retinal lesions: localized and transneuronal up-regulation in the retina and superior colliculus. European Journal of Neuroscience, 22(8), 1840-1852. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=16262624">[More Information]</a> Lai, C., Dunlop, S., May, L., Gorbatov, M., Brankov, M., Shen, W., Binz, N., Lai, Y., Graham, C., Barry, C., Constable, I., Beazley, L., et al (2005). Generation of transgenic mice with mild and severe retinal neovascularisation. British Journal of Ophthalmology, 89(7), 911-916. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=15965177">[More Information]</a> Lai, C., Shen, W., Brankov, M., Lai, Y., Barnett, N., Lee, S., Yeo, I., Mathur, R., Ho, J., Pineda, P., et al (2005). Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization in mice and monkeys. Molecular Therapy, 12(4), 659-668. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=16023893">[More Information]</a> 2004 Shen, W., Lai, Y., Lai, C., Rakoczy, P. (2004). Impurity of recombinant adeno-associated virus type 2 affects the transduction characteristics following subretinal injection in the rat. Vision Research, 44(4), 339-348. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=14659960">[More Information]</a> Shen, W., Lee, S., Yeo, I., Lai, C., Mathur, R., Tan, D., Constable, I., Rakoczy, P. (2004). Predilection of the macular region to high incidence of choroidal neovascularization after intense laser photocoagulation in the monkey. Archives of Ophthalmology, 122(3), 353-360. <a href="http://dx.doi.org/10.1001/archopht.122.3.3 53">[More Information]</a> 2003 Wilson, A., Hobbs, B., Shen, W., Speed, T., Schmidt, U., Begley, C., Rakoczy, P. (2003). Argon Laser Photocoagulation-Induced Modification of Gene Expression in the Retina. Investigative Ophthalmology and Visual Science, 44(4), 1426-1434. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=12657576">[More Information]</a> Kicic, A., Shen, W., Wilson, A., Constable, I., Robertson, T., Rakoczy, P. (2003). Differentiation of Marrow Stromal Cells into Publications for Wei Yong Shen Photoreceptors in the Rat Eye. The Journal of Neuroscience, 23(21), 7742-7749. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=12944502">[More Information]</a> Shen, W., Lai, C., Lai, Y., Zhang, D., Zaknich, T., Sutanto, E., Constable, I., Rakoczy, P. (2003). Practical considerations of recombinant adeno-associated virus-mediated gene transfer for treatment of retinal degenerations. Journal of Gene Medicine, 5(7), 576-587. <a href="http://dx.doi.org/10.1002/jgm.375">[More Information]</a> Daniels, D., Shen, W., Constable, I., Rakoczy, P. (2003). Quantitative model demonstrating that recombinant adeno-associated virus and green fluorescent protein are non-toxic to the rat retina. Clinical and Experimental Ophthalmology, 31. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=14516434">[More Information]</a>