Publications for Tracy Bryan
Publications for Tracy Bryan
2015
2767-2774. <a
href="http://dx.doi.org/10.1182/blood-2014-08-5
96445">[More Information]</a>
Killedar, A., Stutz, M., Sobinoff, A., Tomlinson,
C., Bryan, T., Beesley, J., Chenevix-Trench, G.,
Reddel, R., Pickett, H. (2015). A Common
Cancer Risk-Associated Allele in the hTERT
Locus Encodes a Dominant Negative Inhibitor of
Telomerase. PLoS Genetics, 11(6), 1-23. <a
href="http://dx.doi.org/10.1371/journal.pgen.100
5286">[More Information]</a>
Tomlinson, C., Cohen, S., Bryan, T. (2014).
Inhibition of Telomerase: Promise, Progress and
Potential Pitfalls. In Stephen Neidle (Eds.),
Cancer Drug Design and Discovery, (pp.
491-527). London, United Kingdom: Academic
Press.
Tong, A., Stern, J., Sfeir, A., Kartawinata, M.,
De Lange, T., Zhu, X., Bryan, T. (2015). ATM
and ATR Signaling Regulate the Recruitment of
Human Telomerase to Telomeres. Cell Reports,
13(8), 1-14. <a
href="http://dx.doi.org/10.1016/j.celrep.2015.10.
041">[More Information]</a>
Yatsunyk, L., Bryan, T., Johnson, F. (2012).
G-ruption: the third international meeting on
G-quadruplex and G-assembly. Biochimie,
94(12), 2475-2483. <a
href="http://dx.doi.org/10.1016/j.biochi.2012.09.
002">[More Information]</a>
Birrento, M., Bryan, T., Samosorn, S., Beck, J.
(2015). ESI-MS Investigation of an Equilibrium
between a Bimolecular Quadruplex DNA and a
Duplex DNA/RNA Hybrid. Journal of the
American Society for Mass Spectrometry, 26(7),
1165-1173. <a
href="http://dx.doi.org/10.1007/s13361-015-112
1-2">[More Information]</a>
Moye, A., Bryan, T. (2015). Proteins that interact
with DNA and RNA G-quadruplexes. In David
Monchaud (Eds.), Biological Relevance and
Therapeutic Applications of DNA- and
RNA-Quadruplexes, (pp. 101-117). London:
Future Science Ltd. <a
href="http://dx.doi.org/10.4155/fseb12013.14.22
7">[More Information]</a>
Moye, A., Porter, K., Cohen, S., Phan, T., Zyner,
K., Sasaki, N., Lovrecz, G., Beck, J., Bryan, T.
(2015). Telomeric G-quadruplexes are a
substrate and site of localization for human
telomerase. Nature Communications, 6, 1-12. <a
href="http://dx.doi.org/10.1038/ncomms8643">[
More Information]</a>
Tomlinson, C., Moye, A., Holien, J., Parker, M.,
Cohen, S., Bryan, T. (2015). Two-step
mechanism involving active-site conformational
changes regulates human telomerase DNA
binding. The Biochemical Journal, 465(2),
347-357. <a
href="http://dx.doi.org/10.1042/BJ20140922">[
More Information]</a>
2014
Guo, Y., Kartawinata, M., Li, J., Pickett, H., Teo,
J., Kilo, T., Barbaro, P., Keating, B., Chen, Y.,
Tian, L., Al-Odaib, A., Reddel, R.,
Christodoulou, J., Bryan, T., et al (2014).
Inherited bone marrow failure associated with
germline mutation of ACD, the gene encoding
telomere protein TPP1. Blood, 124(18),
2012
Stern, J., Zyner, K., Pickett, H., Cohen, S.,
Bryan, T. (2012). Telomerase Recruitment
Requires both TCAB1 and Cajal Bodies
Independently. Molecular and Cellular Biology,
32(13), 2384-2395. <a
href="http://dx.doi.org/10.1128/MCB.00379-12"
>[More Information]</a>
Conomos, D., Stutz, M., Hills, M., Neumann, A.,
Bryan, T., Reddel, R., Pickett, H. (2012). Variant
repeats are interspersed throughout the telomeres
and recruit nuclear receptors in ALT cells. The
Journal of Cell Biology, 199(6), 893-906. <a
href="http://dx.doi.org/10.1083/jcb.201207189">
[More Information]</a>
2011
Bryan, T., Baumann, P. (2011). G-Quadruplexes:
From Guanine Gels to Chemotherapeutics.
Molecular Biotechnology, 49(2), 198-208. <a
href="http://dx.doi.org/10.1007/s12033-011-939
5-5">[More Information]</a>
2010
Jurczyluk, J., Nouwens, A., Holien, J., Adams,
T., Lovrecz, G., Parker, M., Cohen, S., Bryan, T.
(2010). Direct involvement of the TEN domain
at the active site of human telomerase. Nucleic
Acids Research, 39(5), 1774-1788. <a
href="http://dx.doi.org/10.1093/nar/gkq1083">[
More Information]</a>
Bryan, T., Baumann, P. (2010). G-quadruplexes:
from guanine gels to chemotherapeutics.
Methods in Molecular Biology, 608, 1-16. <a
href="http://dx.doi.org/10.1007/978-1-59745-36
3-9_1">[More Information]</a>
2009
Bryan, T. (2009). Telomeres and the End
Replication Problem. In Lynne Cox (Eds.),
Molecular Themes in DNA Replication, (pp.
217-268). RSC Publishing.
Publications for Tracy Bryan
2008
Cao, Y., Huschtscha, L., Nouwens, A., Pickett,
H., Neumann, A., Chang, A., Toouli, C., Bryan,
T., Reddel, R. (2008). Amplification of
Telomerase Reverse Transcriptase Gene in
Human Mammary Epithelial Cells with Limiting
Telomerase RNA Expression Levels. Cancer
Research, 68(9), 3115-3123. <a
href="http://dx.doi.org/10.1158/0008-5472.CAN
-07-6377">[More Information]</a>
Cao, Y., Bryan, T., Reddel, R. (2008). Increased
copy number of the TERT and TERC
telomerase subunit genes in cancer cells. Cancer
science, 99(6), 1092-1099. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=18482052">[More Information]</a>
Finger, S., Bryan, T. (2008). Multiple
DNA-binding sites in Tetrahymena telomerase.
Nucleic Acids Research, 36(4), 1260-1272. <a
href="http://dx.doi.org/10.1093/nar/gkm866">[
More Information]</a>
Bryan, T., Stern, J. (2008). Telomerase
recruitment to telomeres. Cytogenetic and
Genome Research, 122(3-4), 243-254. <a
href="http://dx.doi.org/10.1159/000167810">[M
ore Information]</a>
2007
Bryan, T., Jarstfer, M. (2007). Interrogation of
G-quadruplex-protein interactions. Methods,
43(4), 332-339. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17967703">[More Information]</a>
Oganesian, L., Bryan, T. (2007). Physiological
relevance of telomeric G-quadruplex formation:
a potential drug target. BioEssays, 29(2),
155-165. <a
href="http://dx.doi.org/10.1002/bies.20523">[M
ore Information]</a>
Oganesian, L., Graham, M., Robinson, P., Bryan,
T. (2007). Telomerase Recognizes G-Quadruplex
and Linear DNA as Distinct Substrates.
Biochemistry, 46(40), 11279-11290. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17877374">[More Information]</a>
2006
Oganesian, L., Moon, I., Bryan, T., Jarstfer, M.
(2006). Extension of G-quadruplex DNA by
ciliate telomerase. The EMBO Journal, 25(5),
1148-1159. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16511573">[More Information]</a>
Chen, Y., Fender, J., Legassie, J., Jarstfer, M.,
Bryan, T., Varani, G. (2006). Structure of
stem-loop IV of Tetrahymena telomerase RNA.
The EMBO Journal, 25(13), 3156-3166. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16778765">[More Information]</a>
2003
Reddel, R., Bryan, T. (2003). Alternative
lengthening of telomeres: dangerous road less
travelled. The Lancet, 361(9372), 1840-1841.
Bryan, T., Goodrich, K., Cech, T. (2003).
Tetrahymena telomerase is active as a monomer.
Molecular Biology, 14(12), 4794-4804.
2001
Reddel, R., Bryan, T., Colgin, L., Perrem, K.,
Yeager, T. (2001). Alternative lengthening of
telomeres in human cells. Radiation Research,
155(1), 194-200. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=11121234">[More Information]</a>