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Diagnostic and prognostic utility of Mastermind-like 2 (MAML2) gene rearrangement detection by fluorescent in situ hybridization (FISH) in mucoepidermoid carcinoma of the salivary glands. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, 121(5), 530-541. <a href="http://dx.doi.org/10.1016/j.oooo.2016.01.0 03">[More Information]</a> Luk, P., Weston, J., Yu, B., Selinger, C., Ekmejian, R., Eviston, T., Lum, T., Gao, K., Boyer, M., O'Toole, S., Clark, J., Gupta, R. (2016). Salivary duct carcinoma: Clinicopathologic features, morphologic spectrum, and somatic mutations. Head and Neck, 38(Suppl 1), e1838-e1847. <a href="http://dx.doi.org/10.1002/hed.24332">[Mo re Information]</a> Lyle, M., Haydu, L., Menzies, A., Thompson, J., Saw, R., Spillane, A., Kefford, R., Mann, G., Cooper, W., Yu, B., Scolyer, R., O'Toole, S., Long, G. (2016). The molecular profile of metastatic melanoma in Australia. Pathology, 48(2), 188-193. <a href="http://dx.doi.org/10.1016/j.pathol.2015.12. 008">[More Information]</a> 2015 Chou, A., Fraser, S., Toon, C., Clarkson, A., Sioson, L., Farzin, M., Cussigh, C., Aniss, A., O'Neill, C., Watson, N., Clifton-Bligh, R., Learoyd, D., Robinson, B., Delbridge, L., Sidhu, S., O'Toole, S., Sywak, M., Gill, A., et al (2015). A Detailed Clinicopathologic Study of ALK-translocated Papillary Thyroid Carcinoma. American Journal of Surgical Pathology, 39(5), 652-659. <a href="http://dx.doi.org/10.1097/PAS.000000000 0000368">[More Information]</a> Luk, P., Yu, B., Ng, C., Mercorella, B., Selinger, C., Lum, T., Kao, S., O'Toole, S., Cooper, W. (2015). BRAF mutations in non-small cell lung cancer. Translational Lung Cancer Research, 4(2), 142-148. <a href="http://dx.doi.org/10.3978/j.issn.2218-6751. Gallego-Ortega, D., Ledger, A., Roden, D., Law, A., Magenau, A., Kikhtyak, Z., Cho, C., Allerdice, S., Lee, H., Valdes-Mora, F., Naylor, M., O'Toole, S., et al (2015). ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells. PLoS Biology, 13(12), 1-27. <a href="http://dx.doi.org/10.1371/journal.pbio.100 2330">[More Information]</a> Li, B., Lee, A., O'Toole, S., Cooper, W., Yu, B., Chaft, J., Arcila, M., Kris, M., Pavlakis, N. (2015). HER2 insertion YVMA mutant lung cancer: Long natural history and response to afatinib. Lung Cancer, 90(3), 617-619. <a href="http://dx.doi.org/10.1016/j.lungcan.2015.1 0.025">[More Information]</a> Junankar, S., Baker, L., Roden, D., Nair, R., Elsworh, B., Gallego-Ortega, D., Lacaze, P., Cazet, A., Nikolic, I., Teo, W., Naylor, M., O'Toole, S., et al (2015). ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype. Nature Communications, 6, 1-12. <a href="http://dx.doi.org/10.1038/ncomms7548">[ More Information]</a> Luk, P., Selinger, C., Eviston, T., Lum, T., Yu, B., O'Toole, S., Clark, J., Gupta, R. (2015). Mammary analogue secretory carcinoma: an evaluation of its clinicopathological and genetic characteristics. Pathology, 47(7), 659-666. <a href="http://dx.doi.org/10.1097/PAT.000000000 0000322">[More Information]</a> Phua, Y., Nguyen, A., Roden, D., Elsworth, B., Deng, N., Nikolic, I., Yang, J., McFarland, A., Russell, R., Kaplan, W., O'Toole, S., James, D., et al (2015). MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene. Breast Cancer Research, 17(1), 1-18. <a href="http://dx.doi.org/10.1186/s13058-015-059 3-0">[More Information]</a> Gee, H., Buffa, F., Harris, A., Toohey, J., Carroll, S., Cooper, C., Beith, J., McNeil, C., Carmalt, H., Mak, C., Kennedy, C., O'Toole, S., et al (2015). MicroRNA-Related DNA repair/ cell-cycle genes independently associated with relapse after radiation therapy for early breast cancer. International Journal of Radiation Publications for Sandra O'Toole Oncology: Biology Physics, 93(5), 1104-1114. <a href="http://dx.doi.org/10.1016/j.ijrobp.2015.08. 046">[More Information]</a> Cooper, W., Tran, T., Vilain, R., Madore, J., Selinger, C., Kohonen-Corish, M., Yip, P., Yu, B., O'Toole, S., McCaughan, B., Horvath, L., Kao, S., Boyer, M., Scolyer, R., et al (2015). PD-L1 expression is a favorable prognostic factor in early stage non-small cell carcinoma. Lung Cancer, 89(2), 181-188. <a href="http://dx.doi.org/10.1016/j.lungcan.2015.0 5.007">[More Information]</a> Warrier, S., Hwang, S., Gibbings, K., Carmalt, H., O'Toole, S. (2015). Phyllodes tumour with heterologous sarcomatous differentiation: Case series with literature review. International Journal of Surgery Case Reports, 11, 91-94. <a href="http://dx.doi.org/10.1016/j.ijscr.2015.02.0 09">[More Information]</a> Yu, B., O'Toole, S., Trent, R. (2015). Somatic DNA mutation analysis in targeted therapy of solid tumours. Translational Pediatrics, 4(2), 125-138. <a href="http://dx.doi.org/10.3978/j.issn.2224-4336. 2015.04.04">[More Information]</a> Wang, S., Yu, B., Ng, C., Mercorella, B., Selinger, C., O'Toole, S., Cooper, W. (2015). The suitability of small biopsy and cytology specimens for EGFR and other mutation testing in non-small cell lung cancer. Translational Lung Cancer Research, 4(2), 119-125. <a href="http://dx.doi.org/10.3978/j.issn.2218-6751. 2015.01.05">[More Information]</a> 2014 Gibbings, K., Warrier, S., Hwang, S., Rice, M., O'Toole, S., Carmalt, H. (2014). A giant phyllodes tumour with sepsis. ANZ Journal of Surgery, 84(11), 886-887. <a href="http://dx.doi.org/10.1111/ans.12340">[Mo re Information]</a> Tran, T., Selinger, C., Yu, B., Ng, C., Kohonen-Corish, M., McCaughan, B., Kennedy, C., O'Toole, S., Cooper, W. (2014). Alterations of insulin-like growth factor-1 receptor gene copy number and protein expression are common in non-small cell lung cancer. Journal of Clinical Pathology, 67(11), 985-991. <a href="http://dx.doi.org/10.1136/jclinpath-2014-2 02347">[More Information]</a> Nair, R., Roden, D., Teo, W., McFarland, A., Junankar, S., Ye, S., Nguyen, A., Yang, J., Nicolic, I., Hui, M., Armstrong, N., Naylor, M., O'Toole, S., et al (2014). c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer. Oncogene, 33(30), 3992-4002. <a href="http://dx.doi.org/10.1038/onc.2013.368">[ More Information]</a> Kakavand, H., Crainic, O., Lum, T., O'Toole, S., Kefford, R., Thompson, J., Wilmott, J., Long, G., Scolyer, R. (2014). Concordant BRAFV600E mutation status in primary melanomas and associated naevi: implications for mutation testing of primary melanomas. Pathology, 46(3), 193-198. <a href="http://dx.doi.org/10.1097/PAT.000000000 0000077">[More Information]</a> Carlino, M., Haydu, L., Kakavand, H., Menzies, A., Hamilton, A., Yu, B., Ng, C., Cooper, W., Thompson, J., Kefford, R., O'Toole, S., Scolyer, R., Long, G. (2014). Correlation of BRAF and NRAS mutation status with outcome, site of distant metastasis and response to chemotherapy in metastatic melanoma. British Journal of Cancer, 111(2), 292-299. <a href="http://dx.doi.org/10.1038/bjc.2014.287">[ More Information]</a> Houang, M., Sioson, L., Clarkson, A., Watson, N., Mahtab, F., Toon, C., Raut, A., O'Toole, S., Cooper, W., Pavlakis, N., Gill, A., et al (2014). EGFR mutation specific immunohistochemistry is a useful adjunct which helps to identify false negative mutation testing in lung cancer. Pathology, 46(6), 501-508. <a href="http://dx.doi.org/10.1097/PAT.000000000 0000141">[More Information]</a> Menzies, A., Lum, T., Wilmott, J., Hyman, J., Kefford, R., Thompson, J., O'Toole, S., Long, G., Scolyer, R. (2014). Intrapatient Homogeneity of BRAFV600E Expression in Melanoma. The American Journal of Surgical Pathology, 38(3), 377-382. <a href="http://dx.doi.org/10.1097/PAS.000000000 0000136">[More Information]</a> O'Toole, S., Yu, B., Cooper, W. (2014). Molecular Diagnosis in Cytology and Its Place in the New Classification: A Practical Guide. The Journal of OncoPathology, 2(1), 63-73. <a href="http://dx.doi.org/10.13032/tjop.2052-5931. 100080.">[More Information]</a> Cooper, W., Fox, S., O'Toole, S., Morey, A., Frances, G., Pavlakis, N., O'Brien, K., Dettrick, A., Leong, T., Rathi, V., et al (2014). National Working Group Meeting on ALK diagnostics in lung cancer. Asia-Pacific Journal of Clinical Oncology, 10(S 2), 11-17. <a href="http://dx.doi.org/10.1111/ajco.12190">[M ore Information]</a> Houang, M., Toon, C., Clarkson, A., Sioson, L., Watson, N., Farzin, M., Selinger, C., Chou, A., Morey, A., Cooper, W., O'Toole, S., Gill, A. (2014). Reflex ALK immunohistochemistry is feasible and highly specific for ALK gene rearrangements in lung cancer. Pathology, 46(5), Publications for Sandra O'Toole 383-388. <a href="http://dx.doi.org/10.1097/PAT.000000000 0000114">[More Information]</a> Nguyen, N., Hampartzoumian, T., Cameron, B., Palmer, C., O'Toole, S., Post, J., Zekry, A., Lloyd, A. (2014). Regulation of T cell recruitment and inflammation in the human immunodeficiency virus/hepatitis C virus coinfected liver. Journal of Gastroenterology and Hepatology, 29(7), 1535-1543. <a href="http://dx.doi.org/10.1111/jgh.12543">[Mo re Information]</a> 2013 Schade, B., Lesurf, R., Sanguin-Gendreau, V., Bui, T., Deblois, G., O'Toole, S., Millar, E., Zardawi, S., Lopez-Knowles, E., Sutherland, R., et al (2013). B-Catenin Signaling is a Critical Event in ErbB2-Mediated Mammary Tumor Progression. Cancer Research, 73(14), 4474-4487. <a href="http://dx.doi.org/10.1158/0008-5472.CAN -12-3925">[More Information]</a> Klein, O., Clements, A., Menzies, A., O'Toole, S., Kefford, R., Long, G. (2013). BRAF inhibitor activity in V600R metastatic melanoma. European Journal of Cancer, 49(5), 1073-1079. <a href="http://dx.doi.org/10.1016/j.ejca.2012.11.00 4">[More Information]</a> Klein, O., Clements, A., Menzies, A., O'Toole, S., Kefford, R., Long, G. (2013). BRAF inhibitor activity in V600R metastatic melanoma – Response. European Journal of Cancer, 49(7), 1797-1798. <a href="http://dx.doi.org/10.1016/j.ejca.2013.02.01 0">[More Information]</a> O'Toole, S., Rakha, E., Ellis, I., Tan, P. (2013). Breast pathology today: morphology and molecules. Journal of Clinical Pathology, 66(6), 457. <a href="http://dx.doi.org/10.1136/jclinpath-2013-2 01660">[More Information]</a> Cooper, C., O'Toole, S., Kench, J. (2013). Classification, morphology and molecular pathology of premalignant lesions of the pancreas. Pathology, 45(3), 286-304. <a href="http://dx.doi.org/10.1097/PAT.0b013e328 35f2205">[More Information]</a> Cooper, W., Yu, B., Yip, P., Ng, C., Lum, T., Farzin, M., Trent, R., Mercorella, B., Clarkson, A., Kohonen-Corish, M., Horvath, L., Kench, J., McCaughan, B., Gill, A., O'Toole, S. (2013). EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma. Journal of Clinical Pathology, 66(9), 744-748. <a href="http://dx.doi.org/10.1136/jclinpath-2013-2 01607">[More Information]</a> Tran, T., Selinger, C., Kohonen-Corish, M., McCaughan, B., Kennedy, C., O'Toole, S., Cooper, W. (2013). Fibroblast growth factor receptor 1 (FGFR1) copy number is an independent prognostic factor in non-small cell lung cancer. Lung Cancer, 81(3), 462-467. <a href="http://dx.doi.org/10.1016/j.lungcan.2013.0 5.015">[More Information]</a> Browne, B., Hochgrafe, F., Wu, J., Millar, E., Barraclough, J., Stone, A., McCloy, R., Lee, C., Roberts, C., Ali, N., O'Toole, S., et al (2013). Global characterization of signalling networks associated with tamoxifen resistance in breast cancer. The FEBS Journal, 280(21), 5237-5257. <a href="http://dx.doi.org/10.1111/febs.12441">[M ore Information]</a> Cooper, C., Karim, R., Selinger, C., Carmalt, H., Lee, C., O'Toole, S. (2013). Molecular alterations in metaplastic breast carcinoma. Journal of Clinical Pathology, 66(6), 522-528. <a href="http://dx.doi.org/10.1136/jclinpath-2012-2 01086">[More Information]</a> Cooper, W., Lam, D., O'Toole, S., Minna, J. (2013). Molecular biology of lung cancer. Journal of Thoracic Disease, 5(S5), S479-S490. <a href="http://dx.doi.org/10.3978/j.issn.2072-1439. 2013.08.03">[More Information]</a> Cooper, W., O'Toole, S. (2013). Molecular Pathology in lung Cancer. Cancer Forum, 37(2), 1-7. Yip, P., Yu, B., Cooper, W., Selinger, C., Ng, C., Kennedy, C., Kohonen-Corish, M., McCaughan, B., Trent, R., Boyer, M., Kench, J., Horvath, L., O'Toole, S. (2013). Patterns of DNA mutations and ALK Rearrangement in Resected Node Negative Lung Adenocarcinoma. Journal of Thoracic Oncology, 8(4), 408-414. <a href="http://dx.doi.org/10.1097/JTO.0b013e3182 83558e">[More Information]</a> Saunderson, R., Garsia, R., Headley, A., McCaughan, G., O'Toole, S., Strasser, S. (2013). Pentoxifylline-induced drug rash with eosinophilia and systemic symptoms (DRESS) in a patient with caffeine intolerance. Journal of Dermatological Case Reports, 7(3), 77-81. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=24133560">[More Information]</a> Karim, R., O'Toole, S., Scolyer, R., Cooper, C., Chan, B., Selinger, C., Yu, B., Carmalt, H., Mak, C., Tse, G., Lee, C., et al (2013). Recent insights into the molecular pathogenesis of mammary Publications for Sandra O'Toole phyllodes tumours. Journal of Clinical Pathology, 66(6), 496-505. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=23404800">[More Information]</a> Shields, B., Wiede, F., Gurzov, E., Wee, K., Hauser, C., Zhu, H., Molloy, T., O'Toole, S., Daly, R., Sutherland, R., et al (2013). TCPTP Regulates SFK and STAT3 Signaling and Is Lost in Triple-Negative Breast Cancers. Molecular and Cellular Biology, 33(3), 557-570. <a href="http://dx.doi.org/10.1128/MCB.01016-12" >[More Information]</a> Selinger, C., Rogers, T., Russell, P., O'Toole, S., Yip, P., Wright, G., Wainer, Z., Horvath, L., Boyer, M., McCaughan, B., et al (2013). Testing for ALK rearrangement in lung adenocarcinoma: A multicenter comparison of immunohistochemistry and fluorescent in situ hybridization. Modern Pathology, 26(12), 1545-1553. <a href="http://dx.doi.org/10.1038/modpathol.2013. 87">[More Information]</a> Hui, M., Cazet, A., Nair, R., Watkins, D., O'Toole, S., Swarbrick, A. (2013). The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy. Breast Cancer Research, 15(2), 1-14. <a href="http://dx.doi.org/10.1186/bcr3401">[More Information]</a> O'Toole, S., Beith, J., Millar, E., West, R., McLean, A., Cazet, A., Swarbrick, A., Oakes, S. (2013). Therapeutic targets in triple negative breast cancer. Journal of Clinical Pathology, 66(6), 530-542. <a href="http://dx.doi.org/10.1136/jclinpath-2012-2 01361">[More Information]</a> 2012 Coates, A., Millar, E., O'Toole, S., Molloy, T., Viale, G., Goldhirsch, A., Regan, M., Gelber, R., Sun, Z., Castiglione-Gertsch, M., et al (2012). Prognostic interaction between expression of p53 and estrogen receptor in patients with node-negative breast cancer: results from IBCSG Trials VIII and IX. Breast Cancer Research, 14(6), 1-12. <a href="http://dx.doi.org/10.1186/bcr3348">[More Information]</a> 2011 Xu, H., Yan, M., Patra, J., Natrajan, R., Yan, Y., Swagemakers, S., Tomaszewski, J., Verschoor, S., Millar, E., van der Spek, P., O'Toole, S., McNeil, C., et al (2011). Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers. Breast Cancer Research, 13(1), R9-1-R9-36. <a href="http://dx.doi.org/10.1186/bcr2814">[More Information]</a> O'Toole, S., Machalek, D., Shearer, R., Millar, E., Nair, R., Schofield, P., McLeod, D., Cooper, C., McNeil, C., McFarland, A., et al (2011). Hedgehog Overexpression Is Associated with Stromal Interactions and Predicts for Poor Outcome in Breast Cancer. Cancer Research, 71(11), 4002-4014. <a href="http://dx.doi.org/10.1158/0008-5472.CAN -10-3738">[More Information]</a> Roberts, C., Millar, E., O'Toole, S., McNeil, C., Lehrbach, G., Pinese, M., Tobelmann, P., McCloy, R., Musgrove, E., Sutherland, R., et al (2011). Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen responsiveness in breast cancer. Oncogene, 30(28), 3186-3197. <a href="http://dx.doi.org/10.1038/onc.2011.36">[ More Information]</a> O'Toole, S., Selinger, C., Millar, E., Lum, T., Beith, J. (2011). Molecular assays in breast cancer pathology. Pathology, 43(2), 116-127. <a href="http://dx.doi.org/10.1097/PAT.0b013e328 3430926">[More Information]</a> Millar, E., Graham, P., McNeil, C., Browne, L., O'Toole, S., Boulghourjian, A., Kearsley, J., Papadatos, G., Delaney, G., Fox, C., et al (2011). Prediction of outcome of early ER + breast cancer is improved using a biomarker panel, which includes Ki-67 and p53. British Journal of Cancer, 105(2), 272-280. <a href="http://dx.doi.org/10.1038/bjc.2011.228">[ More Information]</a> Colvin, E., Susanto, J., Kench, J., Ong, V., Mawson, A., Pinese, M., Chang, D., Rooman, I., O'Toole, S., Segara, D., et al (2011). Retinoid signaling in pancreatic cancer, injury and regeneration. PloS One, 6(12), e29075 1-e29075 - 10. <a href="http://dx.doi.org/10.1371/journal.pone.002 9075">[More Information]</a> Chan, P., Möller, A., Liu, M., Sceneay, J., Wong, C., Waddell, N., Huang, K., Dobrovic, A., Millar, E., O'Toole, S., et al (2011). The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression. Breast Cancer Research, 13(1), 1-10. <a href="http://dx.doi.org/10.1186/bcr2828">[More Information]</a> Cooper, W., O'Toole, S., Boyer, M., Horvath, L., Mahar, A. (2011). What's new in non-small cell lung cancer for pathologists: the importance of accurate subtyping, EGFR mutations and ALK Publications for Sandra O'Toole rearrangements. Pathology, 43(2), 103-115. <a href="http://dx.doi.org/10.1097/PAT.0b013e328 342629d">[More Information]</a> 2010 Lopez-Knowles, E., Zardawi, S., McNeil, C., Millar, E., Crea, P., Musgrove, E., Sutherland, R., O'Toole, S. (2010). Cytoplasmic Localization of beta-Catenin is a Marker of Poor Outcome in Breast Cancer Patients. Cancer Epidemiology, Biomarkers and Prevention, 19(1), 301-309. <a href="http://dx.doi.org/10.1158/1055-9965.EPI-0 9-0741">[More Information]</a> Zardawi, S., Zardawi, I., McNeil, C., Millar, E., McLeod, D., Morey, A., Crea, P., Murphy, N., Pinese, M., Lopez-Knowles, E., Hamilton, A., Spillane, A., Lee, C., et al (2010). High Notch1 protein expression is an early event in breast cancer development and is associated with the HER-2 molecular subtype. Histopathology, 56(3), 286-296. <a href="http://dx.doi.org/10.1111/j.1365-2559.200 9.03475.x">[More Information]</a> Murphy, N., Biankin, A., Millar, E., McNeil, C., O'Toole, S., Segara, D., Crea, P., Olayioye, M., Lee, C., Fox, S., et al (2010). Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status. International Journal of Cancer, 126(6), 1445-1453. <a href="http://dx.doi.org/10.1002/ijc.24826">[Mor e Information]</a> Fleuren, E., O'Toole, S., Millar, E., McNeil, C., Lopez-Knowles, E., Boulghourjian, A., Croucher, D., Schramek, D., Brummer, T., Penninger, J., et al (2010). Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development. International Journal of Cancer, 127(6), 1486-92. <a href="http://dx.doi.org/10.1002/ijc.25172">[Mor e Information]</a> Lopez-Knowles, E., O'Toole, S., McNeil, C., Millar, E., Qiu, M., Crea, P., Daly, R., Musgrove, E., Sutherland, R. (2010). PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality. International Journal of Cancer, 126(5), 1121-1131. <a href="http://dx.doi.org/10.1002/ijc.24831">[Mor e Information]</a> Nair, R., Junankar, S., O'Toole, S., Shah, J., Borowsky, A., Bishop, J., Swarbrick, A. (2010). 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