Publications for Phillip Robinson
Publications for Phillip Robinson
2016
Luo, L., Xue, J., Kwan, A., Gamsjaeger, R.,
Wielens, J., Von Kleist, L., Cubeddu, L., Guo,
Z., Stow, J., Parker, M., Mackay, J., Robinson, P.
(2016). The binding of syndapin SH3 domain to
dynamin proline-rich domain involves short and
long distance elements. The Journal of
Biological Chemistry, 291(18), 9411-9424. <a
href="http://dx.doi.org/10.1074/jbc.M115.70310
8">[More Information]</a>
2015
Abdel-Hamid, M., Macgregor, K., Odell, L.,
Chau, N., Mariana, A., Whiting, A., Robinson,
P., McCluskey, A. (2015). 1,8-Naphthalimide
derivatives: new leads against dynamin I GTPase
activity. Organic and Biomolecular Chemistry,
13(29), 8016-8028. <a
href="http://dx.doi.org/10.1039/c5ob00751h">[
More Information]</a>
Kettle, E., Page, S., Morgan, G., Malladi, C.,
Wong, C., Boadle, R., Marsh, B., Robinson, P.,
Chircop (nee Fabbro), M. (2015). A
Cholesterol-Dependent Endocytic Mechanism
Generates Midbody Tubules During Cytokinesis.
Traffic: the international journal of intracellular
transport, 16(11), 1174-1192. <a
href="http://dx.doi.org/10.1111/tra.12328">[Mor
e Information]</a>
Lee, A., Slattery, C., Nikolic-Paterson, D.,
Hryciw, D., Wilk, S., Wilk, E., Zhang, Y.,
Valova, V., Robinson, P., Kelly, D., Poronnik, P.
(2015). Chloride channel ClC-5 binds to aspartyl
aminopeptidase to regulate renal albumin
endocytosis. American Journal of Physiology:
Renal Physiology, 308(7), F784-F792. <a
href="http://dx.doi.org/10.1152/ajprenal.00322.2
014">[More Information]</a>
Reid, A., Anderson, A., Roman, S., McLaughlin,
E., McCluskey, A., Robinson, P., Aitken, R.,
Nixon, B. (2015). Glycogen synthase kinase 3
regulates acrosomal exocytosis in mouse
spermatozoa via dynamin phosphorylation. The
FASEB Journal, 29(7), 2872-2882. <a
href="http://dx.doi.org/10.1096/fj.14-265553">[
More Information]</a>
Lian, A., Hains, P., Sarcevic, B., Robinson, P.,
Chircop (nee Fabbro), M. (2015). IQGAP1 is
associated with nuclear envelope reformation
and completion of abscission. Cell Cycle, 14(3),
2058-2074. <a
href="http://dx.doi.org/10.1080/15384101.2015.
1044168">[More Information]</a>
Deloulme, J., Gory-Faure, S., Mauconduit, F.,
Chauvet, S., Jonckheere, J., Boulan, B., Mire, E.,
Xue, J., Jany, M., Maucler, C., Robinson, P., et
al (2015). Microtubule-associated protein 6
mediates neuronal connectivity through
Semaphorin 3E-dependent signalling for axonal
growth. Nature Communications, 6, 1-16. <a
href="http://dx.doi.org/10.1038/ncomms8246">[
More Information]</a>
Kulej, K., Sidoli, S., Palmisano, G., Edwards, A.,
Robinson, P., Larsen, M. (2015). Optimization of
calmodulin-affinity chromatography for brain
and organelles. EuPA Open Proteomics, 8,
55-67. <a
href="http://dx.doi.org/10.1016/j.euprot.2015.05.
004">[More Information]</a>
Daniel, J., Chau, N., Abdel-Hamid, M., Hu, L.,
Von Kleist, L., Whiting, A., Krishnan, S.,
Maamary, P., Joseph, S., Simpson, F., Robinson,
P., et al (2015). Phenothiazine-derived
antipsychotic drugs inhibit dynamin and
clathrin-mediated endocytosis. Traffic (Malden),
16(6), 635-654. <a
href="http://dx.doi.org/10.1111/tra.12272">[Mor
e Information]</a>
Lees, J., Gorgani, N., Ammit, A., McCluskey,
A., Robinson, P., O'Neill, G. (2015). Role of
dynamin in elongated cell migration in a 3D
matrix. BBA: Biochimica et Biophysica Acta Molecular Cell Research, 1853 (3), 611-618. <a
href="http://dx.doi.org/10.1016/j.bbamcr.2014.1
2.008">[More Information]</a>
Krishnan, S., Collett, M., Robinson, P. (2015).
SH3 Domains Differentially Stimulate Distinct
Dynamin I Assembly Modes and G Domain
Activity. PloS One, 10(12), 1-16. <a
href="http://dx.doi.org/10.1371/journal.pone.014
4609">[More Information]</a>
Cai, Y., Postnikova, E., Bernbaum, J., Yu, S.,
Mazur, S., Deiuliis, N., Radoshitzky, S.,
Lackemeyer, M., McCluskey, A., Robinson, P.,
et al (2015). Simian Hemorrhagic Fever Virus
Cell Entry is Dependent on CD163 and Uses a
Clathrin-mediated Endocytosis-like Pathway.
Journal of Virology, 89(1), 844-856. <a
href="http://dx.doi.org/10.1128/JVI.02697-14">[
More Information]</a>
Jackson, J., Papadopulos, A., Meunier, F.,
McCluskey, A., Robinson, P., Keating, D.
(2015). Small molecules demonstrate the role of
dynamin as a bi-directional regulator of the
exocytosis fusion pore and vesicle release.
Molecular Psychiatry, 20(7), 810-819. <a
href="http://dx.doi.org/10.1038/mp.2015.56">[
More Information]</a>
2014
Stahlschmidt, W., Robertson, M., Robinson, P.,
McCluskey, A., Haucke, V. (2014). Clathrin
Terminal Domain-Ligand Interactions Regulate
Sorting of Mannose 6-Phosphate Receptors
Publications for Phillip Robinson
Mediated by AP-1 and GGA Adaptors. Journal
of Biological Chemistry, 289(8), 4906-4918. <a
href="http://dx.doi.org/10.1074/jbc.M113.53521
1">[More Information]</a>
MacGregor, K., Robertson, M., Young, K., Von
Kleist, L., Stahlschmidt, W., Whiting, A., Chau,
N., Robinson, P., Haucke, V., McCluskey, A.
(2014). Development of 1,8-Naphthalimides as
Clathrin Inhibitors. Journal of Medicinal
Chemistry, 57, 131-143. <a
href="http://dx.doi.org/10.1021/jm4015263">[M
ore Information]</a>
MacGregor, K., Abdel-Hamid, M., O'dell, L.,
Chau, N., Whiting, A., Robinson, P., McCluskey,
A. (2014). Development of quinone analogues as
dynamin GTPase inhibitors. European Journal of
Medicinal Chemistry, 85, 191-206. <a
href="http://dx.doi.org/10.1016/j.ejmech.2014.06
.070">[More Information]</a>
Robertson, M., Deane, F., Stahlschmidt, W., Von
Kleist, L., Haucke, V., Robinson, P., McCluskey,
A. (2014). Synthesis of the Pitstop family of
clathrin inhibitors. Nature Protocols, 9(7),
1592-1606. <a
href="http://dx.doi.org/10.1038/nprot.2014.106"
>[More Information]</a>
2013
McCluskey, A., Daniel, J., Hadzic, G., Chau, N.,
Clayton, E., Mariana, A., Whiting, A., Gorgani,
N., Lloyd, J., Quan, A., Moshkanbaryans, L.,
Krishnan, S., Perera, S., Chircop (nee Fabbro),
M., Robinson, P., et al (2013). Building a better
dynasore: the dyngo compounds potently inhibit
dynamin and endocytosis. Traffic (Malden),
14(12), 1272-1289. <a
href="http://dx.doi.org/10.1111/tra.12119">[Mor
e Information]</a>
Myers, S., Malladi, C., Hyland, R., Bautista, T.,
Boadle, R., Robinson, P., Nicholson, G. (2014).
Mutations in the SPTLC1 Protein Cause
Mitochondrial Structural Abnormalities and
Endoplasmic Reticulum Stress in Lymphoblasts.
DNA and Cell Biology, 33(7), 399-407. <a
href="http://dx.doi.org/10.1089/dna.2013.2182">
[More Information]</a>
Gordon, C., Venn-Brown, B., Robertson, M.,
Young, K., Chau, N., Mariana, A., Whiting, A.,
Chircop (nee Fabbro), M., Robinson, P.,
McCluskey, A. (2013). Development of
second-generation indole-based dynamin
GTPase inhibitors. Journal of Medicinal
Chemistry, 56(1), 46-59. <a
href="http://dx.doi.org/10.1021/jm300844m">[
More Information]</a>
Kockx, M., Karunakaran, D., Traini, M., Xue, J.,
Huang, K., Nawara, D., Gaus, K., Jessup, W.,
Robinson, P., Kritharides, L. (2014).
Pharmacological inhibition of dynamin II
reduces constitutive protein secretion from
primary human macrophages. PloS One, 9(10),
1-13. <a
href="http://dx.doi.org/10.1371/journal.pone.011
1186">[More Information]</a>
Smith, C., Haucke, V., McCluskey, A.,
Robinson, P., Chircop (nee Fabbro), M. (2013).
Inhibition of clathrin by pitstop 2 activates the
spindle assembly checkpoint and induces cell
death in dividing HeLa cancer cells. Molecular
Cancer, 12(4), 1-15. <a
href="http://dx.doi.org/10.1186/1476-4598-12-4"
>[More Information]</a>
Daniel, J., Robinson, P. (2014). Rapid analysis of
synaptic vesicle endocytosis in synaptosomes.
In Peter Thorn (Eds.), Exocytosis Methods, (pp.
167-189). New York: Humana Press. <a
href="http://dx.doi.org/10.1007/978-1-62703-67
6-4-9">[More Information]</a>
Quan, A., Robinson, P. (2014). Repurposing
molecular mechanisms of transmitter release: a
new job for syndapin at the fusion pore. Focus on
"Syndapin 3 modulates fusion pore expansion in
mouse neuroendocrine chromaffin cells".
American Journal of Physiology: Cell
Physiology, 306(9), C792-C793. <a
href="http://dx.doi.org/10.1152/ajpcell.00079.20
14">[More Information]</a>
Robertson, M., Deane, F., Robinson, P.,
McCluskey, A. (2014). Synthesis of Dynole
34-2, Dynole 2-24 and Dyngo 4a for
investigating dynamin GTPase. Nature
Protocols, 9(4), 851-870. <a
href="http://dx.doi.org/10.1038/nprot.2014.046"
>[More Information]</a>
Anggono, V., Koc-Schmitz, Y., Widagdo, J.,
Kormann, J., Quan, A., Chen, C., Robinson, P.,
Choi, S., Linden, D., Plomann, M., et al (2013).
PICK1 interacts with PACSIN to regulate
AMPA receptor internalization and cerebellar
long-term depression. Proceedings of the
National Academy of Sciences of the United
States of America (PNAS), 110(34),
13976-13981. <a
href="http://dx.doi.org/10.1073/pnas.131246711
0">[More Information]</a>
McGeachie, A., O'dell, L., Quan, A., Daniel, J.,
Chau, N., Hill, T., Gorgani, N., Keating, D.,
Cousin, M., van Dam, E., Whiting, A., Perera, S.,
Novelle, A., Chircop (nee Fabbro), M.,
Robinson, P., et al (2013). Pyrimidyn
Compounds: Dual-Action Small Molecule
Pyrimidine-Based Dynamin Inhibitors. ACS
Chemical Biology, 8(7), 1507-1518. <a
href="http://dx.doi.org/10.1021/cb400137p">[M
ore Information]</a>
Ma, M., Robinson, P., Chircop (nee Fabbro), M.
(2013). Sorting Nexin 9 Recruits Clathrin Heavy
Publications for Phillip Robinson
Chain to the Mitotic Spindle for Chromosome
Alignment and Segregation. PloS One, 8(7),
1-11. <a
href="http://dx.doi.org/10.1371/journal.pone.006
8387">[More Information]</a>
Quan, A., Robinson, P. (2013). Syndapin - a
membrane remodelling and endocytic F-BAR
protein. The FEBS Journal, 280(21), 5198-5212.
<a
href="http://dx.doi.org/10.1111/febs.12343">[M
ore Information]</a>
Harper, C., Popoff, M., McCluskey, A.,
Robinson, P., Meunier, F. (2013). Targeting
membrane trafficking in infection prophylaxis:
dynamin inhibitors. Trends in Cell Biology,
23(2), 90-101. <a
href="http://dx.doi.org/10.1016/j.tcb.2012.10.00
7">[More Information]</a>
2012
Nguyen, T., Maucort, G., Sullivan, R.,
Schenning, M., Lavidis, N., McCluskey, A.,
Robinson, P., Meunier, F. (2012). Actin- and
Dynamin-Dependent Maturation of Bulk
Endocytosis Restores Neurotransmission
following Synaptic Depletion. PloS One, 7(5),
1-15. <a
href="http://dx.doi.org/10.1371/journal.pone.003
6913">[More Information]</a>
Daniel, J., Malladi, C., Kettle, E., McCluskey,
A., Robinson, P. (2012). Analysis of synaptic
vesicle endocytosis in synaptosomes by
high-content screening. Nature Protocols, 7(8),
1439-1455. <a
href="http://dx.doi.org/10.1038/nprot.2012.070"
>[More Information]</a>
Luwor, R., Chin, X., McCheachie, A., Robinson,
P., Zhu, H. (2012). Dynamin II function is
required for EGF-mediated Stat3 activation but
not Erk1/2 phosphorylation. Growth Factors,
30(4), 220-229. <a
href="http://dx.doi.org/10.3109/08977194.2012.
683189">[More Information]</a>
Reid, A., Lord, T., Stanger, S., Roman, S.,
McCluskey, A., Robinson, P., Aitken, R., Nixon,
B. (2012). Dynamin regulates specific membrane
fusion events necessary for acrosomal exocytosis
in mouse spermatozoa. Journal of Biological
Chemistry, 287(45), 37659-37672. <a
href="http://dx.doi.org/10.1074/jbc.M112.39280
3">[More Information]</a>
Brymora, A., Duggin, I., Berven, L., Van Dam,
E., Roufogalis, B., Robinson, P. (2012).
Identification and Characterisation of the
RalA-ERp57 Interaction: Evidence for GDI
Activity of ERp57. PloS One, 7(11), 1-11. <a
href="http://dx.doi.org/10.1371/journal.pone.005
0879">[More Information]</a>
Smith, C., Bensing, S., Burns, C., Robinson, P.,
Kasperlik-Zaluska, A., Scott, R., Kampe, O.,
Crock, P. (2012). Identification of TPIT and
other novel autoantigens in lymphocytic
hypophysitis: immunoscreening of a pituitary
cDNA library and development of
immunoprecipitation assays. European Journal
of Endocrinology, 166(3), 391-398. <a
href="http://dx.doi.org/10.1530/EJE-11-1015">[
More Information]</a>
Bolderson, E., Savage, K., Mahen, R., Pisupati,
V., Graham, M., Richard, D., Robinson, P.,
Venkitaraman, A., Khanna, K. (2012).
Kruppel-associated Box (KRAB)-associated
co-repressor (KAP-1) Ser-473 phosphorylation
regulates heterochromatin protein 1B (HP1-B)
mobilization and DNA repair in heterochromatin.
Journal of Biological Chemistry, 287(33),
28122-28131. <a
href="http://dx.doi.org/10.1074/jbc.M112.36838
1">[More Information]</a>
Quan, A., Xue, J., Wielens, J., Smillie, K.,
Anggono, V., Parker, M., Cousin, M., Graham,
M., Robinson, P. (2012). Phosphorylation of
syndapin I F-BAR domain at two helix-capping
motifs regulates membrane tubulation.
Proceedings of the National Academy of
Sciences of the United States of America (PNAS),
109(10), 3760-3765. <a
href="http://dx.doi.org/10.1073/pnas.110829410
9">[More Information]</a>
Graham, M., Stone, R., Robinson, P., Payne, R.
(2012). Synthesis and protein binding studies of
a peptide fragment of clathrin assembly protein
AP180 bearing an O-linked
beta-N-acetylglucosaminyl-6-phosphate
modification. Organic and Biomolecular
Chemistry, 10(13), 2545-2551. <a
href="http://dx.doi.org/10.1039/c2ob07139h">[
More Information]</a>
Robertson, M., Hadzic, G., Ambrus, J., Pome,
Y., Hyde, E., Whiting, A., Mariana, A., Von
Kleist, L., Chau, N., Haucke, V., Robinson, P., et
al (2012). The Rhodadyns, a New Class of Small
Molecule Inhibitors of Dynamin GTPase
Activity. ACS Medicinal Chemistry Letters, 3(3),
5-352. <a
href="http://dx.doi.org/10.1021/ml200284s">[M
ore Information]</a>
2011
Graham, M., Thaysen-Andersen, M., Bache, N.,
Craft, G., Larsen, M., Packer, N., Robinson, P.
(2011). A Novel Post-translational Modification
in Nerve Terminals: O-Linked
N-Acetylglucosamine Phosphorylation. Journal
of Proteome Research, 10(6), 2725-2733. <a
href="http://dx.doi.org/10.1021/pr1011153">[M
ore Information]</a>
Publications for Phillip Robinson
Kozlov, S., Graham, M., Jakob, B., Tobias, F.,
Kijas, A., Tanuji, M., Chen, P., Robinson, P.,
Taucher-Scholz, G., Suzuki, K., et al (2011).
Autophosphorylation and ATM activation:
additional sites add to the complexity. Journal of
Biological Chemistry, 286(11), 9107-9119. <a
href="http://dx.doi.org/10.1074/jbc.M110.20406
5">[More Information]</a>
Xue, J., Graham, M., Novelle, A., Sue, N., Gray,
N., McNiven, M., Smillie, K., Cousin, M.,
Robinson, P. (2011). Calcineurin Selectively
Docks with the Dynamin Ixb Splice Variant to
Regulate Activity-dependent Bulk Endocytosis.
Journal of Biological Chemistry, 286(35),
30295-30303. <a
href="http://dx.doi.org/10.1074/jbc.M111.27311
0">[More Information]</a>
Harper, C., Martin, S., Nguyen, T., Daniels, S.,
Lavidis, N., Popoff, M., Hadzic, G., Mariana, A.,
Chau, N., McCluskey, A., Robinson, P., et al
(2011). Dynamin Inhibition Blocks Botulinum
Neurotoxin Type A
Endocytosis in Neurons and Delays Botulism.
Journal of Biological Chemistry, 286(41),
35966-35976. <a
href="http://dx.doi.org/10.1074/jbc.M111.28387
9">[More Information]</a>
Joshi, S., Braithwaite, A., Robinson, P., Chircop
(nee Fabbro), M. (2011). Dynamin inhibitors
induce caspase-mediated
apoptosis following cytokinesis failure in human
cancer cells and this is blocked by Bcl-2
overexpression. Molecular Cancer, 10(78), 1-12.
<a
href="http://dx.doi.org/10.1186/1476-4598-10-7
8">[More Information]</a>
Nguyen, M., Joya, J., Kee, A., Domazetovska,
A., Yang, N., Hook, J., Lemckert, F., Kettle, E.,
Valova, V., Robinson, P., North, K., et al (2011).
Hypertrophy and dietary tyrosine ameliorate the
phenotypes of a mouse model of severe nemaline
myopathy. Brain, 134(Pt12), 3516-3529. <a
href="http://dx.doi.org/10.1093/brain/awr274">[
More Information]</a>
Chircop (nee Fabbro), M., Perera, S., Mariana,
A., Lau, H., Ma, M., Gilbert, J., Jones, N.,
Gordon, C., Young, K., Morokoff, A., Robinson,
P., et al (2011). Inhibition of dynamin by dynole
34-2 induces cell death following cytokinesis
failure in cancer cells. Molecular Cancer
Therapeutics, 10(9), 1553-1562. <a
href="http://dx.doi.org/10.1158/1535-7163.MCT
-11-0067">[More Information]</a>
Chircop (nee Fabbro), M., Sarcevic, B., Larsen,
M., Malladi, C., Chau, N., Zavortink, M., Smith,
C., Quan, A., Anggono, V., Hains, P., Graham,
M., Robinson, P. (2011). Phosphorylation of
dynamin II at serine-764 is associated with
cytokinesis. BBA: Biochimica et Biophysica Acta
- Molecular Cell Research, 1813 (10),
1689-1699. <a
href="http://dx.doi.org/10.1016/j.bbamcr.2010.1
2.018">[More Information]</a>
Woolley, A., Algie, M., Samuel, W., Harfoot, R.,
Wiles, A., Hung, N., Tan, P., Hains, P., Valova,
V., Huschtscha-Holliday, L., Cohen, S.,
Robinson, P., Braithwaite, A., et al (2011).
Prognostic Association of YB-1 Expression in
Breast
Cancers: A Matter of Antibody. PloS One, 6(6),
e20603-1-e20603-13. <a
href="http://dx.doi.org/10.1371/journal.pone.002
0603">[More Information]</a>
Von Kleist, L., Stahlschmidt, W., Bulut, H.,
Gromova, K., Puchkov, D., Robertson, M.,
Kylie, M., MacGregor, K., Tomilin, N., et al,
Chau, N., Chircop (nee Fabbro), M., Robinson,
P. (2011). Role of the Clathrin Terminal Domain
in Regulating Coated Pit Dynamics Revealed by
Small Molecule Inhibition. Cell, 146(3),
471-484. <a
href="http://dx.doi.org/10.1016/j.cell.2011.06.02
5">[More Information]</a>
2010
Sandgren, K., Wilkinson, J., Miranda Saksena,
M., McInerney, G., Byth, K., Robinson, P.,
Cunningham, A. (2010). A differential role for
macropinocytosis in mediating entry of the two
forms of vaccinia virus into dendritic cells. PLoS
Pathogens, 6(4), e1000866-1-e1000866-16. <a
href="http://dx.doi.org/10.1371/journal.ppat.100
0866">[More Information]</a>
Chircop (nee Fabbro), M., Malladi, C., Lian, A.,
Page, S., Zavortink, M., Gordon, C., McCluskey,
A., Robinson, P. (2010). Calcineurin activity is
required for the completion of cytokinesis.
Cellular and Molecular Life Sciences, 67(21),
3725-3737. <a
href="http://dx.doi.org/10.1007/s00018-010-040
1-z">[More Information]</a>
Howes, M., Kirkham, M., Riches, J., Cortese, K.,
Walser, P., Simpson, F., Hill, M., Jones, A.,
Lundmark, R., Lindsay, M., Robinson, P., et al
(2010). Clathrin-independent carriers form a high
capacity endocytic sorting system at the leading
edge of migrating cells. The Journal of Cell
Biology, 190(4), 675-691. <a
href="http://dx.doi.org/10.1083/jcb.201002119">
[More Information]</a>
Chan, L., Hansra, G., Robinson, P., Graham, M.
(2010). Differential Phosphorylation of Dynamin
I Isoforms in Subcellular Compartments
Demonstrates the Hidden Complexity of
Phosphoproteomes. Journal of Proteome
Publications for Phillip Robinson
Research, 9(8), 4028-4037. <a
href="http://dx.doi.org/10.1021/pr100223n">[M
ore Information]</a>
Clayton, E., Sue, N., Smillie, K., O'Leary, T.,
Bache, N., Cheung, G., Cole, A., Wyllie, D.,
Sutherland, C., Robinson, P., et al (2010).
Dynamin I phosphorylation by GSK3 controls
activity-dependent bulk endocytosis of synaptic
vesicles. Nature Neuroscience, 13(7), 845-851.
<a
href="http://dx.doi.org/10.1038/nn.2571">[More
Information]</a>
Susman, R., Quijano-Roy, S., Yang, N., Webster,
R., Clarke, N., Dowling, J., Kennerson, M.,
Nicholson, G., Biancalana, V., Ilkovski, B.,
Vucic, S., North, K., et al (2010). Expanding the
clinical, pathological and MRI phenotype of
DNM2-related centronuclear myopathy.
Neuromuscular Disorders, 20(4), 229-237. <a
href="http://dx.doi.org/10.1016/j.nmd.2010.02.0
16">[More Information]</a>
Cohen, S., Wa, W., Valova, V., Algie, M.,
Harfoot, R., Woolley, A., Robinson, P.,
Braithwaite, A. (2010). Genotoxic stress-induced
nuclear localization of oncoprotein YB-1 in the
absence of proteolytic processing. Oncogene,
29(3), 403-410. <a
href="http://dx.doi.org/10.1038/onc.2009.321">[
More Information]</a>
Hill, T., Mariana, A., Gordon, C., O'dell, L.,
Robertson, M., McGeachie, A., Chau, N., Daniel,
J., Gorgani, N., Robinson, P., et al (2010).
Iminochromene Inhibitors of Dynamins I and II
GTPase Activity and Endocytosis. Journal of
Medicinal Chemistry, 53(10), 4094-4102. <a
href="http://dx.doi.org/10.1021/jm100119c">[M
ore Information]</a>
Baker, M., Smith, N., Hetherington, L.,
Taubman, K., Graham, M., Robinson, P., Aitken,
R. (2010). Label-Free Quantitation of
Phosphopeptide Changes During Rat Sperm
Capacitation. Journal of Proteome Research,
9(2), 718-729. <a
href="http://dx.doi.org/10.1021/pr900513d">[M
ore Information]</a>
Gray, L., Dean, B., Kronsbein, H., Robinson, P.,
Scarr, E. (2010). Region and diagnosis-specific
changes in synaptic proteins in schizophrenia and
bipolar I disorder. Psychiatry Research, 178(2),
374-380. <a
href="http://dx.doi.org/10.1016/j.psychres.2008.
07.012">[More Information]</a>
Joshi, S., Perera, S., Gilbert, J., Smith, C.,
Mariana, A., Gordon, C., Sarkoff, J., McCluskey,
A., Robinson, P., Braithwaite, A., Chircop (nee
Fabbro), M. (2010). The Dynamin Inhibitors
MiTMAB and OcTMAB Induce Cytokinesis
Failure and Inhibit Cell Proliferation in Human
Cancer Cells. Molecular Cancer Therapeutics,
9(7), 1995-2006. <a
href="http://dx.doi.org/10.1158/1535-7163.MCT
-10-0161">[More Information]</a>
O'dell, L., Howan, D., Gordon, C., Robertson,
M., Chau, N., Mariana, A., Whiting, A.,
Abagyan, R., Daniel, J., Gorgani, N., Robinson,
P., et al (2010). The Pthaladyns: GTP
Competitive Inhibitors of Dynamin I and II
GTPase Derived from Virtual Screening. Journal
of Medicinal Chemistry, 53, 5267-5280. <a
href="http://dx.doi.org/10.1021/jm100442u">[M
ore Information]</a>
2009
O'dell, L., Chau, N., Mariana, A., Graham, M.,
Robinson, P., McCluskey, A. (2009). Azido and
Diazarinyl Analogues of Bis-Tyrphostin as
Asymmetrical Inhibitors of Dynamin GTPase.
ChemMedChem: chemistry enabling drug
discovery, 4(7), 1182-1188. <a
href="http://dx.doi.org/10.1002/cmdc.200900054
">[More Information]</a>
Hill, T., Gordon, C., McGeachie, A.,
Venn-Brown, B., O'dell, L., Chau, N., Quan, A.,
Mariana, A., Sakoff, J., Chircop (nee Fabbro),
M., Robinson, P., et al (2009). Inhibition of
dynamin mediated endocytosis by the
dynoles--synthesis and functional activity of a
family of indoles. Journal of Medicinal
Chemistry, 52(12), 3762-73. <a
href="http://dx.doi.org/10.1021/jm900036m">[
More Information]</a>
Kidd, T., Ramsay, K., Hu, H., Bye, P., Elkins,
M., Grimwood, K., Harbour, C., Marks, G.,
Nissen, M., Robinson, P., Rose, B., et al (2009).
Low rates of Pseudomonas aeruginosa
misidentification in isolates from cystic fibrosis
patients. Journal of Clinical Microbiology, 47(5),
1503-1509. <a
href="http://dx.doi.org/10.1128/JCM.00014-09"
>[More Information]</a>
Kidd, T., Marks, G., Bye, P., Wainwright, C.,
Robinson, P., Rose, B., Harbour, C., Bell, S.
(2009). Multi-centre research in Australia:
analysis of a recent National Health and Medical
Research Council-funded project. Respirology,
14(7), 1051-1055. <a
href="http://dx.doi.org/10.1111/j.1440-1843.200
9.01595.x">[More Information]</a>
Veldhuis, N., Valova, V., Gaeth, A., Palstra, N.,
Hannan, K., Michell, B., Kelly, L., Jennings, I.,
Kemp, B., Pearson, R., Robinson, P., et al
(2009). Phosphorylation regulates
copper-responsive trafficking of the Menkes
copper transporting P-type ATPase. The
International Journal of Biochemistry and Cell
Biology, 41(12), 2403-2412. <a
href="http://dx.doi.org/10.1016/j.biocel.2009.06.
Publications for Phillip Robinson
008">[More Information]</a>
Holland, I., McCluskey, A., Sakoff, J., Gilbert,
J., Chau, N., Robinson, P., Motti, C., Wright, A.,
van Altena, I. (2009). Steroids from an
Australian Sponge Psammoclema sp. Journal of
Natural Products, 72(1), 102-106. <a
href="http://dx.doi.org/10.1021/np800688f">[M
ore Information]</a>
Chircop (nee Fabbro), M., Oakes, V., Graham,
M., Ma, M., Smith, C., Robinson, P., Khanna, K.
(2009). The actin-binding and bundling protein,
EPLIN, is required for cytokinesis. Cell Cycle,
8(5), 757-764. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=19221476">[More Information]</a>
Clayton, E., Anggono, V., Smillie, K., Chau, N.,
Robinson, P., Cousin, M. (2009). The
phospho-dependent dynamin-syndapin
interaction triggers activity-dependent bulk
endocytosis of synaptic vesicles. The Journal of
Neuroscience, 29(24), 7706-7717. <a
href="http://dx.doi.org/10.1523/JNEUROSCI.19
76-09.2009">[More Information]</a>
2008
Dunkley, P., Jarvie, P., Robinson, P. (2008). A
rapid Percoll gradient procedure for preparation
of synaptosomes. Nature Protocols, 3(11),
1718-1728. <a
href="http://dx.doi.org/10.1038/nprot.2008.171"
>[More Information]</a>
Robinson, P., Waters, K. (2008). Are children
just small adults? The differences between
paediatric and adult sleep medicine. Internal
Medicine Journal, 38(9), 719-731. <a
href="http://dx.doi.org/10.1111/j.1445-5994.200
8.01719.x">[More Information]</a>
Zhang, J., Lawrance, G., Chau, N., Robinson, P.,
McCluskey, A. (2008). From Spanish fly to
room-temperature ionic liquids (RTILs):
synthesis, thermal stability and inhibition of
dynamin 1 GTPase by a novel class of RTILs.
New Journal of Chemistry, 32(1), 28-36. <a
href="http://dx.doi.org/10.1039/b707092f">[Mor
e Information]</a>
Thingholm, T., Jensen, O., Robinson, P., Larsen,
M. (2008). SIMAC (sequential elution from
IMAC), a phosphoproteomics strategy for the
rapid separation of monophosphorylated from
multiply phosphorylated peptides. Molecular and
Cellular Proteomics, 7(4), 661-671. <a
href="http://dx.doi.org/10.1074/mcp.M700362MCP200">[More Information]</a>
Robinson, P., Anggono, V., Cousin, M. (2008).
Styryl Dye-Based Synaptic Vesicle Recycling
Assay in Cultured Cerebellar Granule Neurons.
In A. Vancura (Eds.), Methods in Molecular
Biology 457: Membrane Trafficking, (pp.
333-345). New Jersey: Humana Press. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=19066039">[More Information]</a>
Tsang, C., Fedchyshyn, M., Harrison, J., Xie, H.,
Xue, J., Robinson, P., Wang, L., Trimble, W.
(2008). Superfluous Role of Mammalian Septins
3 and 5 in Neuronal Development and Synaptic
Transmission. Molecular and Cellular Biology,
28(23), 7012-7029. <a
href="http://dx.doi.org/10.1128/MCB.00035-08"
>[More Information]</a>
Craft, G., Graham, M., Bache, N., Larsen, M.,
Robinson, P. (2008). The in vivo
phosphorylation sites in multiple isoforms of
amphiphysin I from rat brain nerve terminals.
Molecular and Cellular Proteomics, 7(6),
1146-1161. <a
href="http://dx.doi.org/10.1074/mcp.M700351MCP200">[More Information]</a>
2007
Robinson, P., Fitzgerald, D. (2007). Congenital
diaphragmatic hernia. Paediatric Respiratory
Reviews, 8(4), 323-335. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=18005901">[More Information]</a>
Domazetovska, A., Ilkovski, B., Kumar, V.,
Valova, V., Vandebrouck, A., Hutchinson, D.,
Robinson, P., Cooper, S., Sparrow, J., Peckham,
M., North, K. (2007). Intranuclear rod myopathy:
molecular pathogenesis and mechanisms of
weakness. Annals of Neurology, 62(6), 597-608.
<a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17705262">[More Information]</a>
Quan, A., McGeachie, A., Keating, D., Van
Dam, E., Rusak, J., Chau, N., Malladi, C., Chen,
C., McCluskey, A., Cousin, M., Robinson, P.
(2007). Myristyl Trimethyl Ammonium Bromide
and Octadecyl Trimethyl Ammonium Bromide
Are Surface-Active Small Molecule Dynamin
Inhibitors that Block Endocytosis Mediated by
Dynamin I or Dynamin II. Molecular
Pharmacology, 72(6), 1425-1439. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17702890">[More Information]</a>
Robinson, P. (2007). Neuroscience. How to fill a
synapse. Science, 316(5824), 551-553. <a
href="http://dx.doi.org/10.1126/science.1142705
">[More Information]</a>
Cohen, S., Graham, M., Lovrecz, G., Bache, N.,
Robinson, P., Reddel, R. (2007). Protein
composition of catalytically active human
Publications for Phillip Robinson
telomerase from immortal cells. Science,
315(5820), 1850-1853. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17395830">[More Information]</a>
1773 (7), 1062-1072. <a
href="http://dx.doi.org/10.1016/j.bbamcr.2007.0
3.023">[More Information]</a>
Anggono, V., Robinson, P. (2007). Syndapin I
and endophilin I bind overlapping proline-rich
regions of dynamin I: role in synaptic vesicle
endocytosis. Journal of Neurochemistry, 102(3),
931-943. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17437541">[More Information]</a>
Hilliard, L., Osicka, T., Clavant, S., Robinson,
P., Nikolic-Paterson, D., Comper, W. (2006).
Characterization of the urinary albumin
degradation pathway in the isolated perfused rat
kidney. Translational Research: the journal of
laboratory and clinical medicine, 147(1), 36-44.
Oganesian, L., Graham, M., Robinson, P., Bryan,
T. (2007). Telomerase Recognizes G-Quadruplex
and Linear DNA as Distinct Substrates.
Biochemistry, 46(40), 11279-11290. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17877374">[More Information]</a>
Graham, M., Kilby, D., Firth, S., Robinson, P.,
Baxter, R. (2007). The in vivo phosphorylation
and glycosylation of human insulin-like growth
factor binding protein-5. Molecular and Cellular
Proteomics, 6(8), 1392-1405. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17496250">[More Information]</a>
Graham, M., Anggono, V., Bache, N., Larsen,
M., Craft, G., Robinson, P. (2007). The in vivo
phosphorylation sites of rat brain dynamin I.
Journal of Biological Chemistry, 282(20),
14695-14707. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17376771">[More Information]</a>
Clarke, N., Ilkovski, B., Cooper, S., Valova, V.,
Robinson, P., Nonaka, I., Feng, J., Marston, S.,
North, K. (2007). The pathogenesis of
ACTA1-related congenital fiber type
disproportion. Annals of Neurology, 61(6),
552-561. <a
href="http://dx.doi.org/10.1002/ana.21112">[Mo
re Information]</a>
2006
Shipman, K., Robinson, P., King, B., Smith, R.,
Nicholson, R. (2006). Identification of a family
of DNA-binding proteins with homology to RNA
splicing factors. Biochemistry and Cell
Biology-Biochimie et Biologie Cellulaire, 84(1),
9-19.
Kozlov, S., Graham, M., Peng, C., Chen, P.,
Robinson, P., Lavin, M. (2006). Involvement of
novel autophosphorylation sites in ATM
activation. The EMBO Journal, 25(15),
3504-3514.
Van Dam, E., Robinson, P. (2006). Ral:
Mediator of membrane trafficking. The
International Journal of Biochemistry and Cell
Biology, 38(11), 1841-1847. <a
href="http://dx.doi.org/10.1016/j.biocel.2006.04.
006">[More Information]</a>
Anggono, V., Smillie, K., Graham, M., Valova,
V., Cousin, M., Robinson, P. (2006). Syndapin I
is the phosphorylation-regulated dynamin I
partner in synaptic vesicle endocytosis. Nature
Neuroscience, 9(6), 752-760. <a
href="http://dx.doi.org/10.1038/nn1695">[More
Information]</a>
Domazetovska, A., Ilkovski, B., Cooper, S.,
Valova, V., Lemckert, F., Hook, J., Hardeman,
E., Robinson, P., Yang, N., Gunning, P., North,
K. (2006). Unravelling the thin filament:
mechanisms of weakness in inherited muscle
disease. Neuromuscular Disorders, 16(Sup. 1),
S60-S61.
2005
Acevedo, K., Li, R., Soo, P., Suryadinata, R.,
Sarcevic, B., Valova, V., Graham, M., Robinson,
P., Bernard, O. (2007). The phosphorylation of
p25/TPPP by LIM kinase 1 inhibits its ability to
assemble microtubules. Experimental Cell
Research, 313(20), 4091-4106. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=18028908">[More Information]</a>
Chircop (nee Fabbro), M., Zhou, B., Takahashi,
M., Sarcevic, B., Lal, P., Graham, M., Gabrielli,
B., Robinson, P., Nigg, E., Ono, Y., et al (2005).
Cdk1/Erk2- and Plk1-dependent phosphorylation
of a centrosome protein, Cep55, is required for
its recruitment to midbody and cytokinesis.
Developmental Cell, 9(4), 477-488. <a
href="http://dx.doi.org/10.1016/j.devcel.2005.09.
003">[More Information]</a>
Fu, D., van Dam, E., Brymora, A., Duggin, I.,
Robinson, P., Roufogalis, B. (2007). The small
GTPases Rab5 and RalA regulate intracellular
traffic of P-glycoprotein. BBA: Biochimica et
Biophysica Acta - Molecular Cell Research,
Hill, T., Sakoff, J., Robinson, P., McCluskey, A.
(2005). Parallel Solution-Phase Synthesis of
Targeted Tyrphostin Libraries with Anticancer
Activity. Australian Journal of Chemistry, 58(2),
94-103.
Publications for Phillip Robinson
Quan, A., Robinson, P. (2005). Rapid
purification of native dynamin I and colorimetric
GTPase assay. Methods in Enzymology, 404,
556-569. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16413300">[More Information]</a>
Hill, T., O'dell, L., Edwards, J., Graham, M.,
McGeachie, A., Rusak, J., Quan, A., Abagyan,
R., Scott, J., Robinson, P., et al (2005). Small
molecule inhibitors of dynamin I GTPase
activity: Development of dimeric tyrphostins.
Journal of Medicinal Chemistry, 48(24),
7781-7788.
579-590.
2003
Tan, T., Valova, V., Malladi, C., Graham, M.,
Berven, L., Jupp, O., Hansra, G., McClure, S.,
Sarcevic, B., Boadle, R., Robinson, P., et al
(2003). Cdk5 is essential for synaptic vesicle
endocytosis. Nature Cell Biology, 5(8), 701-710.
Cousin, M., Malladi, C., Tan, T., Raymond, C.,
Smillie, K., Robinson, P. (2003). Synapsin
I-associated Phosphatidylinositol 3-kinase
mediates synaptic vesicle delivery to the readily
releasable pool. Journal of Biological Chemistry,
278(31), 29065-29071.
2004
2002
Dubin, M., Stokes, P., Sum, E., Williams, R.,
Valova, V., Robinson, P., Lindeman, G., Glover,
J., Visvader, J., Matthews, J. (2004).
Dimerization Of CtIP, A BRCA1- And
CtBP-Interacting Protein, Is Mediated By An
N-Terminal Coiled-Coil Motif. Journal of
Biological Chemistry, 279(26), 26932-26938.
Garvin, S., McAllister, S., Robinson, P. (2002).
A national initiative: Children of parents with a
mental illness. Youth Studies Australia, 21(2),
17-22.
Larsen, M., Graham, M., Robinson, P.,
Roepstorff, P. (2004). Improved Detection Of
Hydrophilic Phosphopeptides Using Graphite
Powder Microcolumns And Mass Spectrometry:
Evidence For In Vivo Doubly Phosphorylated
Dynamin I And Dynamin Iii. Molecular and
Cellular Proteomics, 3(5), 456-465.
Hill, T., O'Dell, L., Quan, A., Abagyan, R.,
Ferguson, G., Robinson, P., McCluskey, A.
(2004). Long Chain Amines And Long Chain
Ammonium Salts As Novel Inhibitors Of
Dynamin Gtpase Activity. Bioorganic and
Medicinal Chemistry Letters: the tetrahedron
journal for research at the interface of chemistry
and biology, 14(12), 3275-3278. <a
href="http://dx.doi.org/10.1016/j.bmcl.2004.03.0
96">[More Information]</a>
Graham, M., Ruma-Haynes, P., Capes-Davis, A.,
Dunn, J., Tan, T., Valova, V., Robinson, P.,
Jeffrey, P. (2004). Multisite Phosphorylation Of
Doublecortin By Cyclin-Dependent Kinase 5.
Biochemical Journal, 381(2), 471-481.
Fudge, E., Falkov, A., Kowalenko, N., Robinson,
P. (2004). Parenting is a mental health issue.
Australasian Psychiatry, 12(2), 166-171.
Xue, J., Milburn, P., Hanna, B., Graham, M.,
Rostas, J., Robinson, P. (2004). Phosphorylation
Of Septin 3 On Ser-91 By Cgmp-Dependent
Protein Kinase-I In Nerve Terminals.
Biochemical Journal, 381(3), 753-760.
Xue, J., Tsang, C., Gai, W., Malladi, C., Trimble,
W., Rostas, J., Robinson, P. (2004). Septin 3
(G-Septin) Is A Developmentally Regulated
Phosphoprotein Enriched In Presynaptic Nerve
Terminals. Journal of Neurochemistry, 91(3),
Scarr, E., Pavey, G., Robinson, P., Opeskin, D.,
Copolov, D., Dean, B. (2002). Decreased
phorbol ester binding in the parahippocampal
gyrus from subjects with schizophrenia is not
associated with changes in protein kinase C.
Molecular Psychiatry, 7(7), 683-688.
McCluskey, A., Robinson, P., Hill, T., Scott, J.,
Edwards, J. (2002). Green chemistry approaches
to the knoevenagel condensation: comparison of
ethanol, water and solvent free (dry grind)
approaced. Tetrahedron Letters, 43(17),
3117-3120.
O'Dwyer, D., Smith, A., Matthew, M.,
Andronicos, N., Ranson, M., Robinson, P.,
Crock, P. (2002). Identification of the 49-kDa
autoantigen associated with lymphocytic
hypophsitis as beta-enolase. Journal of Clinical
Endocrinology and Metabolism, 87(2), 752-757.
2001
Robinson, P., Harrison-Findik, D., Misra, S.,
Jain, S., Keeler,, M., Powell, K., Malladi, C.,
Varticovski, L. (2001). Dynamin inhibits
phosphatidylinositol 3-kinase in hematopoietic
cells. Biochimica et Biophysica Acta, 1538,
10-19.
Brymora, A., Cousin,, M., Roufogalis, B.,
Robinson, P. (2001). Enhanced Protein Recovery
and Reproducibility from Pull-Down Assays and
Immunoprecipitations using spin columns.
Analytical Biochemistry, 295(1), 119-122.
Robinson, P., Tan, T., Cousin,, M. (2001).
Protein phosphorylation is required to
endocytosis in nerve terminals: potential role for
the dephosphins dynamin I and synaptojanin, but
no AP180 or amphiphysin. Journal of
Neurochemistry, 76, 105-116.
Brymora, A., Roufogalis, B., Robinson, P.,
Publications for Phillip Robinson
Valova, V., Larsen, M. (2001). The brain exocyst
complex interacts with RalA in a GTP-dependent
manner - Identification of a novel mammalian
Sec3 gene and a second Sec15 gene. Journal of
Biological Chemistry, 276(32), 29792-29797.
Robinson, P., Cousin, M. (2001). The
Dephosphins: dephosphorylation by calcineurin
triggers synaptic vesicle endocytosis. Trends in
Neurosciences, 24, 659-665.