Publications for Mark Gorrell
Publications for Mark Gorrell
150608094054">[More Information]</a>
2016
Williams, K., Vieira de Ribeiro, A., Prakoso, E.,
Veillard, A., Shackel, N., Bu, Y., Brooks, B.,
Cavanagh, E., Raleigh, J., McLennan, S.,
McCaughan, G., Keane, F., Twigg, S., Gorrell,
M., et al (2015). Lower serum fibroblast
activation protein shows promise in the exclusion
of clinically significant liver fibrosis due to
non-alcoholic fatty liver disease in diabetes and
obesity. Diabetes Research and Clinical
Practice, 108(3), 466-472. <a
href="http://dx.doi.org/10.1016/j.diabres.2015.02
.024">[More Information]</a>
Chen, Y., Gall, M., Zhang, H., Keane, F.,
McCaughan, G., Yu, M., Gorrell, M. (2016).
Dipeptidyl peptidase 9 enzymatic activity
influences the expression of neonatal metabolic
genes. Experimental Cell Research, 342(1),
72-82. <a
href="http://dx.doi.org/10.1016/j.yexcr.2016.02.
020">[More Information]</a>
Wong, P., Gall, M., Bachovchin, W.,
McCaughan, G., Keane, F., Gorrell, M. (2016).
Neuropeptide Y is a physiological substrate of
fibroblast activation protein: Enzyme kinetics in
blood plasma and expression of Y2R and Y5R in
human liver cirrhosis and hepatocellular
carcinoma. Peptides, 75, 80-95. <a
href="http://dx.doi.org/10.1016/j.peptides.2015.1
1.004">[More Information]</a>
2015
Williams, K., Vieira de Ribeiro, A., Prakoso, E.,
Veillard, A., Shackel, N., Brooks, B., Bu, Y.,
Cavanagh, E., Raleigh, J., McLennan, S.,
McCaughan, G., Keane, F., Gorrell, M., Twigg,
S., et al (2015). Circulating Dipeptidyl
Peptidase-4 Activity Correlates with Measures of
Hepatocyte Apoptosis and Fibrosis in NAFLD in
Type 2 Diabetes Mellitus and Obesity: A Dual
Cohort Cross-Sectional Study. Journal of
Diabetes, 7(6), 809-819. <a
href="http://dx.doi.org/10.1111/1753-0407.1223
7">[More Information]</a>
Zhang, H., Chen, Y., Wadham, C., McCaughan,
G., Keane, F., Gorrell, M. (2015). Dipeptidyl
peptidase 9 subcellular localization and a role in
cell adhesion involving focal adhesion kinase
and paxillin. Biochimica et Biophysica Acta.
Molecular and Cell Biology of Lipids, 1853 (2),
470-480. <a
href="http://dx.doi.org/10.1016/j.bbamcr.2014.1
1.029">[More Information]</a>
Zhang, H., Maqsudi, S., Rainczuk, A., Duffield,
N., Lawrence, J., Keane, F., Justa-Schuch, D.,
Geiss-Friedlander, R., Gorrell, M., Stephens, A.
(2015). Identification of novel dipeptidyl
peptidase 9 substrates by two-dimensional
differential in-gel electrophoresis. The FEBS
Journal, 282(19), 3737-3757. <a
href="http://dx.doi.org/10.1111/febs.13371">[M
ore Information]</a>
Jayawickrama, G., Sadig, R., Sun, G.,
Nematollahi, A., Nadvi, N., Hanrahan, J.,
Gorrell, M., Church, W. (2015). Kynurenine
aminotransferases and the prospects of inhibitors
for the treatment of schizophrenia. Current
Medicinal Chemistry, 22(24), 2902-2918. <a
href="http://dx.doi.org/10.2174/0929867322666
2014
Osborne, B., Yao, T., Wang, X., Chen, Y.,
Kotan, L., Nadvi, N., Herdem, M., McCaughan,
G., Allen, J., Yu, M., Gorrell, M., et al (2014). A
rare variant in human fibroblast activation
protein associated with ER stress, loss of
enzymatic function and loss of cell surface
localisation. Biochimica et Biophysica Acta.
Proteins and Proteomics, 1844 (7), 1248-1259.
<a
href="http://dx.doi.org/10.1016/j.bbapap.2014.03
.015">[More Information]</a>
Nematollahi, A., Church, W., Nadvi, N., Gorrell,
M., Sun, G. (2014). Homology Modeling of
Human Kynurenine Aminotransferase III and
Observations on Inhibitor Binding Using
Molecular Docking. Central Nervous System
Agents in Medicinal Chemistry, 14(1), 2-9. <a
href="http://dx.doi.org/10.2174/1871524914666
140416095523">[More Information]</a>
Keane, F., Yao, T., Seelk, S., Gall, M.,
Chowdhury, S., Poplawski, S., Lai, J., Li, Y.,
Wu, W., Farrell, P., Vieira de Ribeiro, A.,
Osborne, B., Yu, M., Seth, D., Haber, P., Wang,
C., Thomson, S., Twigg, S., McLennan, S.,
McCaughan, G., Gorrell, M., et al (2014).
Quantitation of fibroblast activation protein
(FAP)-specific protease activity in mouse,
baboon and human fluids and organs. FEBS
Open Bio, 4, 43-54. <a
href="http://dx.doi.org/10.1016/j.fob.2013.12.00
1">[More Information]</a>
Hamson, E., Keane, F., Tholen, S., Schilling, O.,
Gorrell, M. (2014). Understanding fibroblast
activation protein (FAP): Substrates, activities,
expression and targeting for cancer therapy.
Proteomics - Clinical Applications, 8, 454-463.
<a
href="http://dx.doi.org/10.1002/prca.201300095"
>[More Information]</a>
2013
Zhang, H., Chen, Y., Keane, F., Gorrell, M.
(2013). Advances in Understanding the
Expression and Function of Dipeptidyl Peptidase
Publications for Mark Gorrell
8 and 9. Molecular Cancer Research, 11(12),
1487-1496. <a
href="http://dx.doi.org/10.1158/1541-7786.MCR
-13-0272">[More Information]</a>
Williams, K., Shackel, N., Gorrell, M.,
McLennan, S., Twigg, S. (2013). Diabetes and
Nonalcoholic Fatty Liver Disease: A Pathogenic
Duo. Endocrine Reviews, 34(1), 84-129. <a
href="http://dx.doi.org/10.1210/er.2012-1009">[
More Information]</a>
Abbott, C., Gorrell, M. (2013). Dipeptidyl
Peptidase 8. In Neil D. Rawlings, Guy Salvesen
(Eds.), Handbook of Proteolytic Enzymes:
Volume 3, (pp. 3379-3384). London, United
Kingdom: Elsevier.
Harstad, E., Rosenblum, J., Gorrell, M.,
Achanzar, W., Minimo, L., Wu, J.,
Rosini-Marthaler, L., Gullo, R., Ordway, N.,
Kirby, M., et al (2013). DPP8 and DPP9
expression in cynomolgus monkey and Sprague
Dawley rat tissues. Regulatory Peptides, 186,
26-35. <a
href="http://dx.doi.org/10.1016/j.regpep.2013.07
.003">[More Information]</a>
Gorrell, M., Park, J. (2013). Fibroblast
Activation Protein alpha. In Neil D. Rawlings,
Guy Salvesen (Eds.), Handbook of Proteolytic
Enzymes: Volume 3, (pp. 3395-3401). London,
United Kingdom: Elsevier.
Chowdhury, S., Chen, Y., Yao, T., Ajami, K.,
Wang, X., Popov, Y., Schuppan, D., Bertolino,
P., McCaughan, G., Yu, M., Gorrell, M. (2013).
Regulation of dipeptidyl peptidase 8 and 9
expression in activated lymphocytes and injured
liver. World Journal of Gastroenterology,
19(19), 2883-2893. <a
href="http://dx.doi.org/10.3748/wjg.v19.i19.288
3">[More Information]</a>
Gall, M., Chen, Y., Vieira de Ribeiro, A., Zhang,
H., Bailey, C., Spielman, D., Yu, M., Gorrell, M.
(2013). Targeted Inactivation of Dipeptidyl
Peptidase 9 Enzymatic Activity Causes Mouse
Neonate Lethality. PloS One, 8(11), 1-10. <a
href="http://dx.doi.org/10.1371/journal.pone.007
8378">[More Information]</a>
2012
Akladios, F., Nadvi, N., Park, J., Hanrahan, J.,
Kapoor, V., Gorrell, M., Church, W. (2012).
Design and synthesis of novel inhibitors of
human kynurenine aminotransferase-I.
Bioorganic & Medicinal Chemistry Letters,
22(4), 1579-1581. <a
href="http://dx.doi.org/10.1016/j.bmcl.2011.12.1
38">[More Information]</a>
Keane, F., Chowdhury, S., Yao, T., Nadvi, N.,
Gall, M., Chen, Y., Osborne, B., Ribeiro, A.,
Church, W., McCaughan, G., Gorrell, M., Yu,
M. (2012). Targeting Dipeptidyl Peptidase-4
(DPP-4) and Fibroblast Activation Protein (FAP)
for Diabetes and Cancer Therapy. In Ben Dunn
(Eds.), Proteinases as Drug Targets, (pp.
118-144). Cambridge, UK: RSC Publishing.
2011
Yao, T., Kim, W., Yu, D., Sharbeen, G.,
McCaughan, G., Choi, K., Xia, P., Gorrell, M.
(2011). A Novel Role of Dipeptidyl Peptidase 9
in Epidermal Growth Factor Signaling.
Molecular Cancer Research, 9(7), 948-959. <a
href="http://dx.doi.org/10.1158/1541-7786.MCR
-10-0272">[More Information]</a>
Lo, L., McLennan, S., Williams, P., Bonner, J.,
Chowdhury, S., McCaughan, G., Gorrell, M.,
Yue, D., Twigg, S. (2011). Diabetes is a
progression factor for hepatic fibrosis in a high
fat fed mouse obesity model of non-alcoholic
steatohepatitis. Journal of Hepatology, 55(2),
435-444. <a
href="http://dx.doi.org/10.1016/j.jhep.2010.10.0
39">[More Information]</a>
Abbott, C., Gorrell, M. (2011). Dipeptidyl
Peptidases (Dpp8) (Japan). Patent No.
4748908.
Abbott, C., Gorrell, M. (2011). Dipeptidyl
Peptidases (Dpp9) (USA). Patent No. 7888094.
Song, S., Shackel, N., Wang, X., Ajami, K.,
McCaughan, G., Gorrell, M. (2011). Discoidin
Domain Receptor 1: Isoform expression and
potential functions in cirrhotic human liver. The
American Journal of Pathology, 178(3),
1134-1144. <a
href="http://dx.doi.org/10.1016/j.ajpath.2010.11.
068">[More Information]</a>
Martin, J., Deacon, C., Gorrell, M., Prins, J.
(2011). Incretin-based therapies - review of the
physiology, pharmacology and emerging clinical
experience. Internal Medicine Journal, 41(4),
299-307. <a
href="http://dx.doi.org/10.1111/j.1445-5994.201
1.02439.x">[More Information]</a>
Martin, J., Deacon, C., Gorrell, M., Prins, J.
(2011). Incretin-based therapies - review of the
physiology, pharmacology and emerging clinical
experience. Internal Medicine Journal, 41(4),
299-307. <a
href="http://dx.doi.org/10.1111/j.1445-5994.201
1.02439.x">[More Information]</a>
Keane, F., Nadvi, N., Yao, T., Gorrell, M.
(2011). Neuropeptide Y, B-type natriuretic
peptide, substance P and peptide YY are novel
substrates of fibroblast activation protein-α. The
FEBS Journal, 278(8), 1316-1332. <a
href="http://dx.doi.org/10.1111/j.1742-4658.201
1.08051.x">[More Information]</a>
Publications for Mark Gorrell
Yu, M., Slaitini, L., Gysbers, V., Riekhoff, A.,
Kähne, T., Knott, H., De Meester, I., Abbott, C.,
McCaughan, G., Gorrell, M. (2011). Soluble
CD26/Dipeptidyl Peptidase IV Enhances Human
Lymphocyte Proliferation In Vitro Independent
of Dipeptidyl Peptidase Enzyme Activity and
Adenosine Deaminase Binding. Scandinavian
Journal of Immunology, 73(2), 102-111. <a
href="http://dx.doi.org/10.1111/j.1365-3083.201
0.02488.x">[More Information]</a>
Gorrell, M., Zekry, A., McCaughan, G., Lloyd,
A. (2011). The long and the short of
interferon-gamma-inducible protein 10 in
hepatitis C virus infection. Hepatology, 54(5),
1875-1879. <a
href="http://dx.doi.org/10.1002/hep.24600">[Mo
re Information]</a>
2010
Kushner, P., Gorrell, M. (2010). DPP-4
Inhibitors in Type 2 Diabetes: Importance of
Selective Enzyme Inhibition and Implications for
Clinical Use. Journal Of Family Practice, 59(2).
Kirby, M., Yu, M., O'Connor, S., Gorrell, M.
(2010). Inhibitor selectivity in the clinical
application of dipeptidyl peptidase-4 inhibition.
Clinical Science, 118(1), 31-41. <a
href="http://dx.doi.org/10.1042/CS20090047">[
More Information]</a>
Gorrell, M., Abbott, C. (2010). Nucleic Acid
Molecules Encoding Prolyl Dipeptidyl
Peptidases [Dipeptidyl Peptidases (Dpp9)].
Patent No. 7662944.
Schuppan, D., Gorrell, M., Klein, T., Mark, M.,
Afdhal, N. (2010). The challenge of developing
novel pharmacological therapies for
non-alcoholic steatohepatitis. Liver
International, 30(6), 795-808. <a
href="http://dx.doi.org/10.1111/j.1478-3231.201
0.02264.x">[More Information]</a>
Yu, M., Yao, T., Chowdhury, S., Nadvi, N.,
Osborne, B., Church, W., McCaughan, G.,
Gorrell, M. (2010). The dipeptidyl peptidase IV
family in cancer and cell biology. The FEBS
Journal, 277(5), 1126-1144. <a
href="http://dx.doi.org/10.1111/j.1742-4658.200
9.07526.x">[More Information]</a>
2009
Sharland, A., Gorrell, M. (2009). Cooperation of
innate and adaptive immunity in the pathogenesis
of biliary atresia: There's a killer on the run.
Hepatology (Baltimore Md.), 50(6), 2037-40.
<a
href="http://dx.doi.org/10.1002/hep.23399">[Mo
re Information]</a>
Manos, J., Arthur, J., Rose, B., Bell, S., Tingpej,
P., Hu, H., Webb, J., Kjelleberg, S., Gorrell, M.,
Bye, P., Harbour, C. (2009). Gene expression
characteristics of a cystic fibrosis epidemic strain
of Pseudomonas aeruginosa during biofilm and
planktonic growth. FEMS Microbiology Letters,
292(1), 107-114. <a
href="http://dx.doi.org/10.1111/j.1574-6968.200
8.01472.x">[More Information]</a>
Yu, M., Ajami, K., Gall, M., Park, J., Lee, C.,
Evans, K., McLaughlin, E., Pitman, M., Abbott,
C., McCaughan, G., Gorrell, M. (2009). The In
Vivo Expression of Dipeptidyl Peptidases 8 and
9. Journal of Histochemistry and Cytochemistry:
imaging the spectrum of cell biology, 57(11),
1025-1040. <a
href="http://dx.doi.org/10.1369/jhc.2009.953760
">[More Information]</a>
2008
Devanshi, S., Hogg, P., Gorrell, M., McCaughan,
G., Haber, P. (2008). Direct effects of alcohol on
hepatic fibrinolytic balance: implications for
alcoholic liver disease. Journal of Hepatology,
48(4), 614-627. <a
href="http://dx.doi.org/10.1016/j.jhep.2007.12.0
15">[More Information]</a>
Wang, X., Yao, T., Nadvi, N., Osborne, B.,
McCaughan, G., Gorrell, M. (2008). Fibroblast
activation protein and chronic liver disease.
Frontiers in Bioscience, 13, 3168-3180. <a
href="http://dx.doi.org/10.2741/2918">[More
Information]</a>
Gorrell, M. (2008). Impaired glucose tolerance
and incretins in chronic liver disease. Journal of
Gastroenterology and Hepatology, 23(2),
166-167. <a
href="http://dx.doi.org/10.1111/j.1440-1746.200
7.05268.x">[More Information]</a>
Neuman, M., Sha, K., Esguerra, R., Zakhari, S.,
Winkler, R., Hilzenrat, N., Wyse, J., Cooper, C.,
Seth, D., Gorrell, M., Haber, P., McCaughan, G.,
et al (2008). Inflammation and Repair in Viral
Hepatitis C. Digestive Diseases and Sciences,
53(6), 1468-1487. <a
href="http://dx.doi.org/10.1007/s10620-007-004
7-3">[More Information]</a>
Tran, D., Christiansen, D., Winterhalter, A.,
Brooks, A., Gorrell, M., Lilienfeld, B., Seebach,
J., Sandrin, M., Sharland, A. (2008). Porcine
cells express more than one functional ligand for
the human lymphocyte activating receptor
NKG2D. Xenotransplantation, 15(5), 321-332.
<a
href="http://dx.doi.org/10.1111/j.1399-3089.200
8.00489.x">[More Information]</a>
Park, J., Knott, H., Nadvi, N., Collyer, C., Wang,
X., Church, W., Gorrell, M. (2008). Reversible
Inactivation of Human Dipeptidyl Peptidases 8
and 9 by Oxidation. The Open Enzyme Inhibition
Publications for Mark Gorrell
Journal, 1, 52-60.
Ajami, K., Pitman, M., Wilson, C., Park, J.,
Menz, R., Starr, A., Cox, J., Abbott, C., Overall,
C., Gorrell, M. (2008). Stromal cell-derived
factors 1alpha and 1beta, inflammatory
protein-10 and interferon-inducible T cell
chemo-attractant are novel substrates of
dipeptidyl peptidase 8. FEBS Letters, 582(5),
819-825. <a
href="http://dx.doi.org/10.1016/j.febslet.2008.02.
005">[More Information]</a>
Manos, J., Arthur, J., Rose, B., Tingpej, P., Fung,
C., Curtis, M., Webb, J., Hu, H., Kjelleberg, S.,
Gorrell, M., Bye, P., Harbour, C. (2008).
Transcriptome analyses and biofilm-forming
characteristics of a clonal Pseudomonas
aeruginosa from the cystic fibrosis lung. Journal
of Medical Microbiology, 57(12), 1454-1465. <a
href="http://dx.doi.org/10.1099/jmm.0.2008/005
009-0">[More Information]</a>
2007
Abbott, C., Gorrell, M. (2007). Dipeptidyl
Peptidases (Dpp9). Patent No. 1337629,
7276365. Austria, Belgium, Cyprus, Denmark,
Finland, France, Germany, Greece, Ireland, Italy,
Luxembourg, Monaco, Netherlands, Portugal,
Spain, Sweden, Switzerland, Turkey, United
Kingdom.
Gorrell, M., Warner, F. (2007). Fooling the liver:
Malaria incognito. Hepatology, 45(3), 826-826.
<a
href="http://dx.doi.org/10.1002/hep.21567">[Mo
re Information]</a>
McCaughan, G., Shackel, N., Williams, R., Seth,
D., Haber, P., Gorrell, M. (2007). Genomics,
gene arrays and proteomics in the study of liver
disease. In Juan Rodes, Jean-Pierre Benhamou,
Andres Blei, Juerg Reichen, and Mario Rizzetto
(Eds.), The Textbook of Hepatology: From Basic
Science to Clinical Practice, (pp. 398-420).
USA: Blackwell Publishers.
Gorrell, M. (2007). Liver fibrosis: The
hepatocyte revisited. Hepatology (Baltimore
Md.), 46(5), 1659-61. <a
href="http://dx.doi.org/10.1002/hep.22003">[Mo
re Information]</a>
Huang, X., McCaughan, G., Shackel, N., Gorrell,
M. (2007). Up-regulation of proproliferative
genes and the ligand/receptor pair placental
growth factor and vascular endothelial growth
factor receptor 1 in hepatitis C cirrhosis. Liver
International, 27(7), 960-968. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17696935">[More Information]</a>
2006
Banavar, M., Kable, E., Braet, F., Wang, X.,
Gorrell, M., Cox, G. (2006). Detection of
Collagen by Second Harmonic Microscopy as a
Diagnostic Tool for Liver Fibrosis. Multiphoton
Microscopy in the Biomedical Sciences VI,
Bellingham, Washington, USA: SPIE International Society for Optical Engineering.
Park, J., Ajami, K., Yu, M., Gorrell, M. (2006).
Dipeptidyl peptidase 8 has post-proline
dipeptidyl aminopeptidase and prolyl
endopeptidase activities. Advances in
Experimental Medicine and Biology, 575,
93-102. <a
href="http://dx.doi.org/10.1007/0-387-32824-6-1
0">[More Information]</a>
Abbott, C., Gorrell, M. (2006). Dipeptidyl
Peptidases (Dpp8). Patent No. 1214344,
7148338. Austria, Belgium, Cyprus, Denmark,
Finland, France, Germany, Greece, Ireland, Italy,
Luxembourg, Monaco, Netherlands, Portugal,
Spain, Sweden, Switzerland, United Kingdom.
Yu, M., Wang, X., Ajami, K., McCaughan, G.,
Gorrell, M. (2006). DP8 and DP9 have
extra-enzymatic roles in cell adhesion, migration
and apoptosis. Advances in Experimental
Medicine and Biology, 575, 63-72. <a
href="http://dx.doi.org/10.1007/0-387-32824-6-7
">[More Information]</a>
Wang, X., Yu, M., McCaughan, G., Gorrell, M.
(2006). Extra-enzymatic roles of DPIV and FAP
in cell adhesion and migration on collagen and
fibronectin. Advances in Experimental Medicine
and Biology, 575, 213-222. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16700525">[More Information]</a>
Yu, M., Wang, X., McCaughan, G., Gorrell, M.
(2006). Extraenzymatic functions of the
dipeptidyl peptidase IV-related proteins DP8 and
DP9 in cell adhesion, migration and apoptosis.
The FEBS Journal, 273(11), 2447-2460. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16704418">[More Information]</a>
Seth, D., Hogg, P., Gorrell, M., McCaughan, G.,
Haber, P. (2006). Identification of novel
therapeutic targets for alcoholic liver disease.
International Society for Biomedical Research
on Alcoholism World congress on Alcohol
Research (ISBRA 2006), Maryland:
Wiley-Blackwell Publishing.
Seth, D., Gorrell, M., Cordoba, S., McCaughan,
G., Haber, P. (2006). Intrahepatic gene
expression in human alcoholic hepatitis. Journal
of Hepatology, 45(2), 306-320. <a
href="http://dx.doi.org/10.1016/j.jhep.2006.04.0
13">[More Information]</a>
Publications for Mark Gorrell
Chen, T., Ajami, K., McCaughan, G., Gai, W.,
Gorrell, M., Abbott, C. (2006). Molecular
characterization of a novel dipeptidyl peptidase
like 2-short form (DPL2-s) that is highly
expressed in the brain and lacks dipeptidyl
peptidase activity. Biochimica et Biophysica
Acta, 1764 (1), 33-43. <a
href="http://dx.doi.org/10.1016/j.bbapap.2005.09
.013">[More Information]</a>
M. (2004). Dipeptidyl Peptidase 9 Has Two
Forms, A Broad Tissue Distribution,
Cytoplasmic Localization And DPIV-Like
Peptidase Activity. Biochimica et Biophysica
Acta, 1679 (1), 18-28. <a
href="http://dx.doi.org/10.1016/j.bbaexp.2004.03
.010">[More Information]</a>
Abbott, C., Gorrell, M. (2006). Patent No.
7148338.
Cox, G., Kable, E., Jones, A., Fraser, I.,
Manconi, F., Gorrell, M. (2003). 3-Dimensional
imaging of collagen using second harmonic
generation. Journal of Structural Biology,
141(1), 53-62.
Seth, D., Beard, M., Gorrell, M., McCaughan,
G., Haber, P. (2006). Osteopontin: An early
marker for alcoholic liver injury? Alcoholism:
Clinical and Experimental Research, 30(s2),
89A-89A.
Gorrell, M., Wang, X., Park, J., Ajami, K., Yu,
M., Knott, H., Seth, D., McCaughan, G. (2006).
Structure and function in dipeptidyl peptidase IV
and related proteins. Advances in Experimental
Medicine and Biology, 575, 45-54. <a
href="http://dx.doi.org/10.1007/0-387-32824-6-5
">[More Information]</a>
Shackel, N., Seth, D., Haber, P., Gorrell, M.,
McCaughan, G. (2006). The hepatic
transcriptome in human liver disease.
Comparative Hepatology, 5, 6-6. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17090326">[More Information]</a>
2005
Gorrell, M. (2005). Dipeptidyl peptidase IV and
related enzymes in cell biology and liver
disorders. Clinical Science, 108(4), 277-292.
Gorrell, M., Yu, M. (2005). Diverse functions in
a conserved structure: The dipeptidyl peptidase
IV gene family. In Robinson J (Eds.), Trends in
Protein Research, (pp. 1-78). New York: Nova
Biomedical Books.
Wang, X., Yu, M., McCaughan, G., Gorrell, M.
(2005). Fibroblast activation protein increases
apoptosis, cell adhesion, and migration by the
LX-2 human stellate cell line. Hepatology, 42(4),
935-945. <a
href="http://dx.doi.org/10.1002/hep.20853">[Mo
re Information]</a>
Wang, X., Yu, D., Schnapp, A., Marguet, D.,
Cordoba, S., Retting, W., McCaughan, G.,
Gorrell, M. (2005). The role of fibroblast
activation protein (FAP) in cell adhesion,
migration and liver fibrosis. 56th Annual
Meeting of the American Association for the
Study of Liver Diseases, United States: John
Wiley & Sons.
2004
Ajami, K., Abbott, C., McCaughan, G., Gorrell,
2003
Stockel-Maschek, A., Stiebitz, B., Faust, J.,
Born, I., Kahne, T., Gorrell, M., Neubert, K.
(2003). Different inhibition mechanisms of
dipeptidyl peptidaseIV by tryptophan containing
peptides and amides. In M. Hildebrandt, B. F.
Klapp, T. Hoffman and H.-U. Demuth (Eds.),
Dipeptidyl Aminopeptidases in Health and
Disease, (pp. 69-72). NY: Springer.
Lorey, S., Stockel-Maschek, A., Faust, J.,
Brandt, W., Stiebitz, B., Gorrell, M., Kahne, T.,
Mrestani-Klaus, C., Wrenger, S., Reinhold, D., et
al (2003). Different modes of dipetidyl pepidase
IV (CD26) inhibition by oligopeptides derived
from the N-terminus of HIV-1 Tat indicate at
least two inhibitor binding sites. The FEBS
Journal, 270(10), 2147-2156.
Chen, T., Ajami, K., McCaughan, G., Gorrell,
M., Abbott, C. (2003). Dipeptidyl peptidase IV
gene family. In M. Hildebrandt, B. F. Klapp, T.
Hoffman and H.-U. Demuth (Eds.), Dipeptidyl
Aminopeptidases in Health and Disease, (pp.
79-88). NY: Springer.
Gorrell, M. (2003). First bite. Nature Structural
and Molecular Biology, 10(1), 3-5.
Seth, D., Leo, M., McGuinness, P., Lieber, C.,
Brennan, Y., Williams, R., Wang, X.,
McCaughan, G., Gorrell, M., Haber, P. (2003).
Gene expression profiling of alcoholic liver
disease in the Baboon (Papio hamadryas) and
human liver. The American Journal of
Pathology, 163(6), 2303-2317.
Gorrell, M., Wang, X., Levy, M., Kable, E.,
Marinos, G., Cox, G., McCaughan, G. (2003).
Intrahepatic expression of collagen and fibroblast
activation protein (FAP) in hepatitis C virus
infection. In M. Hildebrandt, B. F. Klapp, T.
Hoffman and H.-U. Demuth (Eds.), Dipeptidyl
Aminopeptidases in Health and Disease, (pp.
235-243). NY: Springer.
Ajami, K., Abbott, C., Gysbers, V., Kaehne, T.,
McCaughan, G., Gorrell, M. (2003). Molecular
chimeras and mutational analysis in the prolyl
oligopeptidase gene family. In M. Hildebrandt,
B. F. Klapp, T. Hoffman and H.-U. Demuth
Publications for Mark Gorrell
(Eds.), Dipeptidyl Aminopeptidases in Health
and Disease, (pp. 49-55). NY: Springer.
Shackel, N., McGuiness, P., Abbott, C., Gorrell,
M., McCaughan, G. (2003). Novel differential
gene expression in human cirrhosis detected by
suppression substractive hybridization.
Hepatology, 38(3), 577-588.
Haber, P., Warner, R., Seth, D., Gorrell, M.,
McCaughan, G. (2003). Pathogenesis and
management of alcoholic hepatitis. Journal of
Gastroenterology and Hepatology, 18(12),
1332-1344.
Seth, D., Gorrell, M., McGuiness, P., Leo, M.,
Lieber, C., McCaughan, G., Haber, P. (2003).
SMART amplification maintains representation
of relative gene expression: quantitative
validation by real time PCR and application to
studies of alcoholic liver disease in primates.
Journal Of Biochemical and Biophysical
Methods, 55(1), 53-66.
Ajami, K., Abbott, C., Obradovic, M., Gysbers,
V., Kahne, T., McCaughan, G., Gorrell, M.
(2003). Structural requirements for catalysis,
expression, dimerization in the CD26/DPIV gene
family. Biochemistry, 42(3), 694-701.
2002
Shackel, N., Gorrell, M., McCaughan, G. (2002).
Gene array analysis and the liver. Hepatology,
36(6), 1313-1325.
Wang, M., Gorrell, M., Abbott, C., Jaggi, R.,
Marguet, D., Dickinson, R. (2002). Hepatic
covalent adduct formation with zomepirac in the
CD26-deficient mouse. Journal of
Gastroenterology and Hepatology, 17(1), 66-71.
Shackel, N., McGuinness, P., Abbott, C., Gorrell,
M., McCaughan, G. (2002). Insights into the
pathobiology of hepatitis C virus-associated
cirrhosis. The American Journal of Pathology,
160(2), 641-654.
Levy, M., McCaughan, G., Marinos, G., Gorrell,
M. (2002). Intrahepatic expression of the hepatic
stellate cell marker fibroblast activation protein
correlates with the degree of fibrosis in hepatitis
C virus infection. Liver International, 22(2),
93-101.
Abbott, C., Gorrell, M. (2002). The family of
CD26/DPIV and related ectopeptidases: the
DPIV family. In J Langner, S Ansorge (Eds.),
Ectopeptises: CD13/Aminopeptidase N and
CD26/Dipeptidylpeptidase IV in Medicine and
Biology, (pp. 171-194). New York, USA:
Staempfli Publishers Ltd.
2000
McCaughan, G., Gorrell, M., Bishop, A., Abbott,
C., Shackel, N., McGuinness, P., Levy, M.,
Sharland, A., Bowen, D., Yu, M., Slaitini, L.,
Napoli, J., et al (2000). Molecular pathogenesis
of liver disease: an approach to hepatic
inflammation, cirrhosis and liver transplant
tolerance. Immunological Reviews, 174(1),
172-191.