Publications for Meilang Xue Publications for Meilang Xue u254">[More Information]</a> 2015 Xue, M., Shen, K., McKelvey, K., Li, J., Chan, Y., Hatzis, V., March, L., Little, C., Tonkin, M., Jackson, C. (2014). Endothelial protein C receptor associated invasiveness of rheumatoid synovial fibroblasts is likely driven by group V secretory phospholipase A2. Arthritis Research & Therapy, 16(1), 1-12. <a href="http://dx.doi.org/10.1186/ar4473">[More Information]</a> Xue, M., Jackson, C. (2015). Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring. Advances in Wound Care, 4(3), 119-136. <a href="http://dx.doi.org/10.1089/wound.2013.048 5">[More Information]</a> Xue, M., Jackson, C. (2015). Novel Functions of the Anticoagulant Activated Protein C in Maintaining Skin Barrier Integrity to Impact on Skin Disease. Pathobiology: exploring the basis of disease, 82(2), 100-106. <a href="http://dx.doi.org/10.1159/000430957">[M ore Information]</a> Whitmont, K., McKelvey, K., Fulcher, G., Reid, I., March, L., Xue, M., Cooper, A., Jackson, C. (2015). Treatment of chronic diabetic lower leg ulcers with activated protein C: a randomised placebo-controlled, double-blind pilot clinical trial. International Wound Journal, 12(4), 422-427. <a href="http://dx.doi.org/10.1111/iwj.12125">[Mo re Information]</a> 2014 Shen, K., Murphy, C., Chan, B., Kolind, M., Cheng, T., Cheng, T., Mikulec, K., Peacock, L., Xue, M., Park, S., Little, D., Jackson, C., Schindeler, A. (2014). Activated Protein C (APC) can Increase Bone Anabolism via a Protease Activated Receptor (PAR)1/2 Dependent Mechanism. Journal of Orthopaedic Research, 32(12), 1549-1556. <a href="http://dx.doi.org/10.1002/jor.22726">[Mor e Information]</a> Xue, M., Jackson, C. (2014). Activated Protein C and its Potential Applications in Prevention of Islet B-cell Damage and Diabetes. In Gerald Litwack (Eds.), Vitamins and Hormones: The Pancreatic Beta Cell, (pp. 323-363). London: Elsevier. <a href="http://dx.doi.org/10.1016/B978-0-12-8001 74-5.00013-2">[More Information]</a> McKelvey, K., Jackson, C., Xue, M. (2014). Activated protein C: A regulator of human skin epidermal keratinocyte function. World Journal of Biological Chemistry, 5(2), 169-179. <a href="http://dx.doi.org/10.4331/wjbc.v5.i2.169"> [More Information]</a> Xue, M., McKelvey, K., Shen, K., Minhas, N., March, L., Park, S., Jackson, C. (2014). Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation. Rheumatology, 53(12), 2270-2279. <a href="http://dx.doi.org/10.1093/rheumatology/ke 2013 Lee, Y., Jeong, J., Seol, J., Xue, M., Jackson, C., Park, S. (2013). Activated protein C differentially regulates both viability and differentiation of osteoblasts mediated by bisphosphonates. Experimental and Molecular Medicine, 45, 1-7. <a href="http://dx.doi.org/10.1038/emm.2013.16">[ More Information]</a> Akbari, M., Dadadashian, F., Kordestani, S., Xue, M., Jackson, C. (2013). Enzymatic modification of regenerated cellulosic fabrics to improve bacteria sorption properties. Journal of Biomedical Materials Research. Part A, 101A (6), 1734-1742. <a href="http://dx.doi.org/10.1002/jbm.a.34478">[ More Information]</a> Whitmont, K., Fulcher, G., Reid, I., Xue, M., McKelvey, K., Xie, Y., Aboud, M., Ward, C., Smith, M., Cooper, A., March, L., Jackson, C. (2013). Low Circulating Protein C Levels Are Associated with Lower Leg Ulcers in Patients with Diabetes. BioMed Research International, 2013, 1-4. <a href="http://dx.doi.org/10.1155/2013/719570">[ More Information]</a> 2012 Xue, M., Dervish, S., Harrison, L., Fulcher, G., Jackson, C. (2012). Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice. Journal of Biological Chemistry, 287(20), 16356-16364. <a href="http://dx.doi.org/10.1074/jbc.M111.32595 1">[More Information]</a> McKelvey, K., Xue, M., Whitmont, K., Shen, K., Cooper, A., Jackson, C. (2012). Potential anti-inflammatory treatments for chronic wounds. Wound Practice & Research, 20(2), 86-89. Xue, M., Chan, A., Shen, K., Dervish, S., March, L., Sambrook, P., Jackson, C. (2012). Protease-Activated Receptor 2, Rather Than Protease-Activated Receptor 1, Contributes to the Aggressive Properties of Synovial Fibroblasts in Rheumatoid Arthritis. Arthritis & Rheumatology, 64(1), 88-98. <a Publications for Meilang Xue href="http://dx.doi.org/10.1002/art.33323">[Mor e Information]</a> 2011 Xue, M., Chow, S., Dervish, S., Chan, Y., Julovi, S., Jackson, C. (2011). Activated Protein C Enhances Human Keratinocyte Barrier Integrity via Sequential Activation of Epidermal Growth Factor Receptor and Tie2. Journal of Biological Chemistry, 286(8), 6742-6750. <a href="http://dx.doi.org/10.1074/jbc.M110.18138 8">[More Information]</a> Jackson, C., Xue, M. (2011). Anti-Inflammatory Actions of the Anticoagulant, Activated Protein C. In Amit Nagal (Eds.), Inflammatory Diseases - A Modern Perspective, (pp. 45-72). Rijeka: InTech Publishers. Moon, M., Jeong, J., Seo, J., Seol, J., Lee, Y., Xue, M., Jackson, C., Park, S. (2011). Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation. Experimental and Molecular Medicine, 43(3), 138-145. <a href="http://dx.doi.org/10.3858/emm.2011.43.3. 016">[More Information]</a> Julovi, S., Xue, M., Dervish, S., Sambrook, P., March, L., Jackson, C. (2011). Protease Activated Receptor-2 Mediates Activated Protein C-Induced Cutaneous Wound Healing via Inhibition of p38. The American Journal of Pathology, 179(5), 2233-2242. <a href="http://dx.doi.org/10.1016/j.ajpath.2011.07. 024">[More Information]</a> 2010 Minhas, N., Xue, M., Fukudome, K., Jackson, C. (2010). Activated protein C utilizes the angiopoietin/Tie2 axis to promote endothelial barrier function. The F A S E B Journal, 24(3), 873-881. <a href="http://dx.doi.org/10.1096/fj.09-134445">[ More Information]</a> Xue, M., Minhas, N., Chow, S., Dervish, S., Sambrook, P., March, L., Jackson, C. (2010). Endogenous protein C is essential for the functional integrity of human endothelial cells. Cellular and Molecular Life Sciences, 67(9), 1537-1546. <a href="http://dx.doi.org/10.1007/s00018-010-026 9-y">[More Information]</a> 2009 Xue, M., Smith, M., Little, C., Sambrook, P., March, L., Jackson, C. (2009). Activated protein C mediates a healing phenotype in cultured tenocytes. Journal of Cellular and Molecular Medicine, 13(4), 749-757. <a href="http://dx.doi.org/10.1111/j.1582-4934.200 8.00359.x">[More Information]</a> Jackson, M., Smith, M., Smith, S., Jackson, C., Xue, M., Little, C. (2009). Activation of Cartilage Matrix Metalloproteinases by Activated Protein C. Arthritis & Rheumatology, 60(3), 780-791. <a href="http://dx.doi.org/10.1002/art.24303">[Mor e Information]</a> Xue, A., Xue, M., Jackson, C., Smith, R. (2009). Suppression of urokinase plasminogen activator receptor inhibits proliferation and migration of pancreatic adenocarcinoma cells via regulation of ERK/p38 signaling. The International Journal of Biochemistry and Cell Biology, 41(8-9), 1731-1738. <a href="http://dx.doi.org/10.1016/j.biocel.2009.03. 004">[More Information]</a> 2008 Jackson, C., Xue, M. (2008). Activated protein C-An anticoagulant that does more than stop clots. The International Journal of Biochemistry and Cell Biology, 40(12), 2692-2697. <a href="http://dx.doi.org/10.1016/j.biocel.2007.12. 013">[More Information]</a> Xue, M., Jackson, C. (2008). Autocrine Actions of Matrix Metalloproteinase (MMP)-2 Counter the Effects of MMP-9 to Promote Survival and Prevent Terminal Differentiation of Cultured Human Keratinocytes. Journal of Investigative Dermatology, 128(11), 2676-2685. <a href="http://dx.doi.org/10.1038/jid.2008.136">[ More Information]</a> Jackson, C., Whitmont, K., Tritton, S., March, L., Sambrook, P., Xue, M. (2008). New therapeutic applications for the anticoagulant, activated protein C. Expert Opinion on Biological Therapy, 8(8), 1109-1122. <a href="http://dx.doi.org/10.1517/14712598.8.8.11 09">[More Information]</a> Wang, W., Xue, M., Willcox, M., Thakur, A. (2008). Role of Nitric Oxide in P. aeruginosa Keratitis Caused by Distinct Bacterial Phenotypes. Eye and Contact Lens, 34(4), 195-197. <a href="http://dx.doi.org/10.1097/ICL.0b013e3181 59b009">[More Information]</a> Whitmont, K., Reid, I., Tritton, S., March, L., Xue, M., Lee, M., Fulcher, G., Sambrook, P., Slobedman, E., Cooper, A., Jackson, C. (2008). Treatment of chronic leg ulcers with topical activated protein C. Archives of Dermatology, 144(11), 1479-1483. <a href="http://dx.doi.org/10.1001/archderm.144.11 .1479">[More Information]</a> 2007 Xue, M., Thakur, A., Cole, N., Lloyd, A., Stapleton, F., Wakefield, D., Willcox, M. (2007). A critical role for CCL2 and CCL3 chemokines Publications for Meilang Xue in the regulation of polymorphonuclear neutrophils recruitment during corneal infection in mice. Immunology and Cell Biology, 85(7), 525-531. <a href="http://dx.doi.org/10.1038/sj.icb.7100082"> [More Information]</a> Xue, M., March, L., Sambrook, P., Jackson, C. (2007). Differential Regulation of Matrix Metalloproteinase 2 and Matrix Metalloproteinase 9 by Activated Protein C: Relevance to Inflammation in Rheumatoid Arthritis. Arthritis & Rheumatology, 56(9), 2864-2874. <a href="http://dx.doi.org/10.1002/art.22844">[Mor e Information]</a> Xue, M., March, L., Sambrook, P., Fukudome, K., Jackson, C. (2007). Endothelial protein C receptor is over-expressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes. Annals of the Rheumatic Diseases, 66(12), 1574-1580. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17491095">[More Information]</a> Xue, M., Campbell, D., Jackson, C. (2007). Protein C is an autocrine growth factor for human skin keratinocytes. Journal of Biological Chemistry, 282(18), 13610-13616. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17293597">[More Information]</a> Le, N., Xue, M., Castelnoble, L., Jackson, C. (2007). The dual personalities of matrix metalloproteinases in inflammation. Frontiers in Bioscience, 12, 1475-1487. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17127395">[More Information]</a> 2006 Jackson, C., Xue, M. (2006). Activated protein C (APC) as a novel agent to promote wound healing. Primary Intention, 14(1), 31-34. Xue, M., Thompson, P., Sambrook, P., March, L., Jackson, C. (2006). Activated protein C stimulates expression of angiogenic factors in human skin cells, angiogenesis in the chick embryo and cutaneous wound healing in rodents. Clinical Hemorheology and Microcirculation, 34, 153-161. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=16543631">[More Information]</a> Little, C., Jackson, M., Smith, M., Burkhardt, D., Xue, M., Jackson, C. (2006). Potential role of activated protein C (APC) in articular cartilage degeneration. 49th Annual Meeting of the Orthopaedic Research Society, United states: Orthopaedic Research Society. Xue, M., Jackson, C., Le, N. (2006). Targeting matrix metalloproteases to improve cutaneous wound healing. Expert Opinion on Therapeutic Targets, 10(1), 143-155. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=16441234">[More Information]</a> 2005 Jackson, C., Xue, M., Thompson, P., Davey, R., Whitmont, K., Smith, S., Buisson-Legendre, N., Sztynda, T., Furphy, L., Cooper, A., Sambrook, P., March, L. (2005). Activated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healing. Wound Repair and Regeneration, 13(3), 284-294. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=15953048">[More Information]</a> Xue, M., Campbell, D., Sambrook, P., Fukudome, K., Jackson, C. (2005). Endothelial Protein C Receptor and Protease-Activated Receptor-1 Mediate Induction of a Wound-Healing Phenotype in Human Keratinocytes by Activated Protein C. Journal of Investigative Dermatology, 125(6), 1279-1285. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=16354200">[More Information]</a> Xue, M., Thompson, P., Clifton-Bligh, R., Fulcher, G., Gallery, E., Jackson, C. (2005). Leukocyte matrix metalloproteinase-9 is elevated and contributes to lymphocyte activation in type I diabetes. The International Journal of Biochemistry and Cell Biology, 37(11), 2406-2416. <a href="http://dx.doi.org/10.1016/j.biocel.2005.06. 003">[More Information]</a> 2004 Xue, M., Thompson, P., Kelso, I., Jackson, C. (2004). Activated Protein C Stimulates Proliferation, Migration And Wound Closure, Inhibits Apoptosis And Upregulates Mmp-2 Activity In Cultured Human Keratinocytes. Experimental Cell Research, 299(1), 119-127.