Publications for Linda Bendall
Publications for Linda Bendall
2015
Daver, N., Boumber, Y., Kantarjian, H.,
Ravandi, F., Cortes, J., Rytting, M., Kawedia, J.,
Basnett, J., Culotta, K., Zeng, Z., Bendall, L., et
al (2015). A Phase I/II Study of the mTOR
Inhibitor Everolimus in Combination with
HyperCVAD Chemotherapy in Patients with
Relapsed/Refractory Acute Lymphoblastic
Leukemia. Clinical Cancer Research, 21(12),
2704-2714. <a
href="http://dx.doi.org/10.1158/1078-0432.CCR14-2888">[More Information]</a>
Welschinger, R., Bendall, L. (2015). Temporal
tracking of cell cycle progression using flow
cytometry without the need for synchronization.
Journal of Visualized Experiments, 2015 (102),
1-10. <a
href="http://dx.doi.org/10.3791/52840">[More
Information]</a>
2014
Bendall, L., Green, D. (2014). Autopsy of a cell.
Leukemia, 28(6), 1341-1343. <a
href="http://dx.doi.org/10.1038/leu.2014.17">[M
ore Information]</a>
Wong, J., Welschinger, R., Hewson, J.,
Bradstock, K., Bendall, L. (2014). Efficacy of
dual PI-3K and mTOR inhibitors in vitro and in
vivo in acute lymphoblastic leukemia.
Oncotarget, 5(21), 10460-10472.
Lymphoblastic Leukemia by Enhancing MYC
Expression. Cancer Research, 74(10),
2803-2815. <a
href="http://dx.doi.org/10.1158/0008-5472.CAN
-13-2732">[More Information]</a>
2013
Winkler, I., Bendall, L., Forristal, C., Helwani,
F., Nowlan, B., Barbier, V., Shen, Y., Cisterne,
A., Sedger, L., Levesque, J. (2013).
B-lymphopoiesis is stopped by mobilizing doses
of G-CSF and is rescued by overexpression of
the anti-apoptotic protein Bcl2. Haematologica,
98(3), 325-333. <a
href="http://dx.doi.org/10.3324/haematol.2012.0
69260">[More Information]</a>
Wallington-Beddoe, C., Bradstock, K., Bendall,
L. (2013). Oncogenic properties of sphingosine
kinases in haematological malignancies. British
Journal of Haematology, 161(5), 623-638. <a
href="http://dx.doi.org/10.1111/bjh.12302">[Mo
re Information]</a>
Welschinger, R., Liedtke, F., Basnett, J., Dela
Pena, A., Juarez, J., Bradstock, K., Bendall, L.
(2013). Plerixafor (AMD3100) induces
prolonged mobilization of acute lymphoblastic
leukemia cells and increases the proportion of
cycling cells in the blood in mice. Experimental
Hematology, 41(3), 293-302.e1. <a
href="http://dx.doi.org/10.1016/j.exphem.2012.1
1.004">[More Information]</a>
Bendall, L., Bradstock, K. (2014). G-CSF: From
granulopoietic stimulant to bone marrow stem
cell mobilizing agent. Cytokine & Growth Factor
Reviews, 25(4), 355-367. <a
href="http://dx.doi.org/10.1016/j.cytogfr.2014.07
.011">[More Information]</a>
Saunders, P., Weiss, J., Welschinger, R., Baraz,
R., Bradstock, K., Bendall, L. (2013). RAD001
(everolimus) induces dose-dependent changes to
cell cycle regulation and modifies the cell cycle
response to vincristine. Oncogene, 32(40),
4789-4797. <a
href="http://dx.doi.org/10.1038/onc.2012.498">[
More Information]</a>
Baraz, R., Cisterne, A., Saunders, P., Hewson, J.,
Thien, M., Weiss, J., Basnett, J., Bradstock, K.,
Bendall, L. (2014). mTOR inhibition by
everolimus in childhood acute lymphoblastic
leukemia induces caspase-independent cell
death. PloS One, 9(7), 1-10. <a
href="http://dx.doi.org/10.1371/journal.pone.010
2494">[More Information]</a>
Bendall, L., Basnett, J. (2013). Role of
sphingosine 1-phosphate in trafficking and
mobilization of hematopoietic stem cells.
Current Opinion In Hematology, 20(4), 281-288.
<a
href="http://dx.doi.org/10.1097/MOH.0b013e32
83606090">[More Information]</a>
Cisterne, A., Baraz, R., Khan, N., Welschinger,
R., Basnett, J., Fung, C., Rizos, H., Bradstock,
K., Bendall, L. (2014). Silencer of death domains
controls cell death through tumour necrosis
factor-receptor 1 and caspase-10 in acute
lymphoblastic leukemia. PloS One, 9(7), 1-10.
<a
href="http://dx.doi.org/10.1371/journal.pone.010
3383">[More Information]</a>
Wallington-Beddoe, C., Powell, J., Tong, D.,
Pitson, S., Bradstock, K., Bendall, L. (2014).
Sphingosine Kinase 2 Promotes Acute
2012
Harun, N., Bradstock, K., Bendall, L. (2012).
Combination Strategies for Stem Cell
Mobilization Targeting CXCR4 and S1P
Receptors. In Stefan Fruehauf, W. Jens Zeller
and Gary Calandra (Eds.), Novel Developments
in Stem Cell Mobilization, (pp. 37-54). New
York: Springer Science+Business Media.
Wallington-Beddoe, C., Don, A., Hewson, J.,
Qiao, Q., Papa, R., Lock, R., Bradstock, K.,
Bendall, L. (2012). Disparate In Vivo Efficacy of
FTY720 in Xenograft Models of Philadelphia
Publications for Linda Bendall
Positive and Negative B-lineage Acute
Lymphoblastic Leukemia. PloS One, 7(5), 1-7.
<a
href="http://dx.doi.org/10.1371/journal.pone.003
6429">[More Information]</a>
Klionsky, D., Abdalla, F., Abeliovich, H.,
Abraham, R., Acevedo-Arozena, A., Adeli, K.,
Agholme, L., Agnello, M., Agostinis, P.,
Aguirre-Ghiso, J., Bendall, L., Feng, C., Sidhu,
S., Xia, P., et al (2012). Guidelines for the use
and interpretation of assays for monitoring
autophagy. Autophagy, 8(4), 445-544. <a
href="http://dx.doi.org/10.4161/auto.19496">[M
ore Information]</a>
Winkler, I., Pettit, A., Raggatt, L., Jacobsen, R.,
Forristal, C., Barbier, V., Nowlan, B., Cisterne,
A., Bendall, L., Sims, N., et al (2012).
Hematopoietic stem cell mobilizing agents
G-CSF, cyclophosphamide or AMD3100 have
distinct mechanisms of action on bone marrow
HSC niches and bone formation. Leukemia,
26(7), 1594-1601. <a
href="http://dx.doi.org/10.1038/leu.2012.17">[M
ore Information]</a>
Khan, N., Cisterne, A., Baraz, R., Bradstock, K.,
Bendall, L. (2012). Para-NO-aspirin inhibits
NF-kB and induces apoptosis in B-cell
progenitor acute lymphoblastic leukemia.
Experimental Hematology, 40(3), 207-215.e1. <a
href="http://dx.doi.org/10.1016/j.exphem.2011.1
1.001">[More Information]</a>
Juarez, J., Harun, N., Thien, M., Welschinger,
R., Baraz, R., Dela Pena, A., Pitson, S., Rettig,
M., DiPersio, J., Bradstock, K., Bendall, L.
(2012). Sphingosine-1-phosphate facilitates
trafficking of hematopoietic stem cells and their
mobilization by CXCR4 antagonists in mice.
Blood, 119(3), 707-716. <a
href="http://dx.doi.org/10.1182/blood-2011-04-3
48904">[More Information]</a>
2011
Wallington-Beddoe, C., Hewson, J., Bradstock,
K., Bendall, L. (2011). FTY720 produces
caspase-independent cell death of acute
lymphoblastic leukemia cells. Autophagy, 7(7),
707-715. <a
href="http://dx.doi.org/10.4161/auto.7.7.15154">
[More Information]</a>
Bendall, L. (2011). It's all in the timing. Blood,
118(23), 5983-5984. <a
href="http://dx.doi.org/10.1182/blood-2011-09-3
81111">[More Information]</a>
To, L., Levesque, J., Herbert, K., Winkler, I.,
Bendall, L., Hiwase, D., Antonenas, V., Rice, A.,
Gottlieb, D., Mills, A., Rasko, J., et al (2011).
Mobilisation strategies for normal and malignant
cells. Pathology, 43(6), 547-565. <a
href="http://dx.doi.org/10.1097/PAT.0b013e328
34a9eb8">[More Information]</a>
Saunders, P., Cisterne, A., Weiss, J., Bradstock,
K., Bendall, L. (2011). The mammalian target of
rapamycin inhibitor RAD001 (everolimus)
synergizes with chemotherapeutic agents,
ionizing radiation and proteasome inhibitors in
pre-B acute lymphocytic leukemia.
Haematologica, 96(1), 69-77. <a
href="http://dx.doi.org/10.3324/haematol.2010.0
26997">[More Information]</a>
Wei, J., Yee, C., Ramanathan, P., Bendall, L.,
Williamson, P. (2011). Variation in
Immunophenotype of Lactating Mice. American
Journal of Reproductive Immunology, 89,
178-184. <a
href="http://dx.doi.org/10.1016/j.jri.2011.02.008
">[More Information]</a>
2010
Sedger, L., Katewa, A., Petterson, A., Osvath, S.,
Farrell, G., Stewart, G., Bendall, L., Alexander,
S. (2010). Extreme lymphoproliferative disease
and fatal autoimmune thrombocytopenia in
FasL- and TRAIL-double deficient mice. Blood,
115(16), 3258-3268. <a
href="http://dx.doi.org/10.1182/blood-2009-11-2
55497">[More Information]</a>
Bendall, L. (2010). New and Emerging Drug
Targets for the Treatment of Hematological
Malignancies. Current Drug Targets, 11(7),
767-8. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=20370651">[More Information]</a>
Deo, S., Bendall, L. (2010). The Potential and
Limitations of p38MAPK as a Drug Target for
the Treatment of Hematological Malignancies.
Current Drug Targets, 11(7), 823-833. <a
href="http://dx.doi.org/10.2174/1389450107913
20854">[More Information]</a>
2009
Juarez, J., Thien, M., Dela Pena, A., Baraz, R.,
Bradstock, K., Bendall, L. (2009). CXCR4
mediates the homing of B cell progenitor acute
lymphoblastic leukaemia cells to the bone
marrow via activation of p38MAPK. British
Journal of Haematology, 145, 491-499. <a
href="http://dx.doi.org/10.1111/j.1365-2141.200
9.07648.x">[More Information]</a>
Crazzolara, R., Bendall, L. (2009). Emerging
treatments in acute lymphoblastic leukemia.
Current Cancer Drug Targets, 9(1), 19-31. <a
href="http://dx.doi.org/10.2174/1568009097873
14057">[More Information]</a>
Deo, S., Bradstock, K., Bendall, L. (2009).
p38MAPK inhibitors attenuate cytokine
Publications for Linda Bendall
production by bone marrow stromal cells and
reduce stroma-mediated proliferation of acute
lymphoblastic leukemia cells. Cell Cycle, 8(18),
2977-2985. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=19713744">[More Information]</a>
Crazzolara, R., Cisterne, A., Thien, M., Hewson,
J., Baraz, R., Bradstock, K., Bendall, L. (2009).
Potentiating effects of RAD001 (Everolimus) on
vincristine therapy in childhood acute
lymphoblastic leukemia. Blood, 113(14),
3297-3306. <a
href="http://dx.doi.org/10.1182/blood-2008-02-1
37752">[More Information]</a>
Crazzolara, R., Bradstock, K., Bendall, L.
(2009). RAD001 (Everolimus) induces
autophagy in acute lymphoblastic leukemia.
Autophagy, 5(5), 727-728. <a
href="http://dx.doi.org/10.4161/auto.5.5.8507">[
More Information]</a>
Johnson, M., Sharma, M., Jamieson, C.,
Henderson, J., Mok, M., Bendall, L., Henderson,
B. (2009). Regulation of beta-catenin trafficking
to the membrane in living cells. Cellular
Signalling, 21(2), 339-348. <a
href="http://dx.doi.org/10.1016/j.cellsig.2008.11.
004">[More Information]</a>
2008
Khan, N., Cisterne, A., Devidas, M., Shuster, J.,
Hunger, S., Shaw, P., Bradstock, K., Bendall, L.
(2008). Expression of CD44, but not CD44v6,
predicts relapse in children with B cell
progenitor acute lymphoblastic leukemia lacking
adverse or favorable genetics. Leukemia and
Lymphoma, 49(4), 710-718. <a
href="http://dx.doi.org/10.1080/1042819070186
1660">[More Information]</a>
2007
Khan, N., Bradstock, K., Bendall, L. (2007).
Activation of Wnt/beta-catenin pathway
mediates growth and survival in B-cell
progenitor acute lymphoblastic leukaemia.
British Journal of Haematology, 138(3),
338-348. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17614820">[More Information]</a>
Juarez, J., Dela Pena, A., Baraz, R., Hewson, J.,
Khoo, M., Cisterne, A., Fricker, S., Fujii, N.,
Bradstock, K., Bendall, L. (2007). CXCR4
antagonists mobilize childhood acute
lymphoblastic leukemia cells into the peripheral
blood and inhibit engraftment. Leukemia, 21(6),
1249-1257. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17410186">[More Information]</a>
Juarez, J., Baraz, R., Deo, S., Bradstock, K.,
Bendall, L. (2007). Interaction of interleukin-7
and interleukin-3 with the CXCL12-induced
proliferation of B-cell progenitor acute
lymphoblastic leukemia. Haematologica, 92(4),
450-459. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17488655">[More Information]</a>
2006
Belov, L., Mulligan, S., Barber, N., Woolfson,
A., Scott, M., Stoner, K., Chrisp, J., Sewell, W.,
Bradstock, K., Bendall, L., Sartor, M., Young,
G., Wiley, J., Christopherson, R., et al (2006).
Analysis of human leukaemias and lymphomas
using extensive immunophenotypes from an
antibody microarray. British Journal of
Haematology, 135(2), 184-97. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16939496">[More Information]</a>
Christopherson, R., Stoner, K., Barber, N.,
Belov, L., Woolfson, A., Scott, M., Bendall, L.,
Mulligan, S. (2006). Classification of AML
using a monoclonal antibody microarray.
Methods in molecular medicine, 125, 241-251.
<a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16502589">[More Information]</a>
Khan, N., Bendall, L. (2006). Role of WNT
signaling in normal and malignant
hematopoiesis. Histology and Histopathology:
cellular and molecular biology, 21(7), 761-774.
<a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16598675">[More Information]</a>
2005
Sedger, L., Bendall, L., Gottlieb, D., Alexander,
S., Osvath, S. (2005). A novel mechanism of
viral subversion of TNF-R signalling by the
poxvirus TNF-R like protein, T2. 35th Annual
Scientific Meeting of the Australasian Society for
Immunology 2005, Denmark: Blackwell
Munksgaard.
Bendall, L. (2005). Chemokines and their
receptors in disease. Histology and
Histopathology: cellular and molecular biology,
20(3), 907-926. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15944942">[More Information]</a>
Juarez, J., Hewson, J., Cisterne, A., Baraz, R.,
Bradstock, K., Bendall, L. (2005). CXCR4
antagonists mobilize acute lymphoblastic
Publications for Linda Bendall
leukemia cells into the peripheral blood and
inhibit engraftment in mice. 47th Annual
Meeting of the American Society of Hematology
(ASH), United States: American Society of
Hematology.
Wnt/beta-catenin pathway promotes growth and
survival of acute lymphoblastic leukaemia (ALL)
cells in vitro. 47th Annual Meeting of the
American Society of Hematology (ASH), United
States: American Society of Hematology.
Bendall, L., Baraz, R., Juarez, J., Shen, W.,
Bradstock, K. (2005). Defective p38
mitogen-activated protein kinase signaling
impairs chemotaxic but not proliferative
responses to stromal-derived factor-1alpha in
acute lymphoblastic leukemia. Cancer Research.
<a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15833862">[More Information]</a>
2004
Campana, D., Iwamoto, D., Bendall, L.,
Bradstock, K. (2005). Growth requirements and
immunophenotype of acute lymphoblastic
leukemia progenitors. Blood, 105(10), 4150. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15867424">[More Information]</a>
Sloane, A., Raso, V., Dimitrov, D., Xiao, X.,
Deo, S., Muljadi, N., Restuccia, D., Turville, S.,
Kearney, C., Broder, C., Zoellner, H.,
Cunningham, A., Bendall, L., Lynch, G. (2005).
Marked structural and functional heterogeneity
in CXCR4: Separation of HIV-1 and SDF-1
alpha responses. Immunology and Cell Biology,
83(2), 129-143. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15748209">[More Information]</a>
Bendall, L., Bradstock, K. (2005). New therapies
targeting chemokine receptors: Can changing the
way cells traffic be used to treat human disease?
Current Topics in Membranes, 55, 331-365.
Juarez, J., Bendall, L., Bradstock, K. (2004).
Chemokines And Their Receptors As
Therapeutic Targets: The Role Of The
Sdf-1/Cxcr4 Axis. Current Pharmaceutical
Design, 10(11), 1245-1259.
McGowan, E., Saad, S., Bendall, L., Bradstock,
K., Clarke, C. (2004). Effect Of Progesterone
Receptor A Predominance On Breast Cancer Cell
Migration Into Bone Marrow Fibroblasts. Breast
Cancer Research and Treatment, 83(3), 211-220.
Bendall, L., Nilsson, S., Khan, N., James, A.,
Bonnet, C., Lock, R., Papa, R., Bradstock, K.,
Gottlieb, D. (2004). Role of CD44 variant exon 6
in acute lymphoblastic leukaemia: association
with altered bone marrow localisation and
increased tumor burden. Leukemia, 18(7),
1308-1311.
Juarez, J., Bendall, L. (2004). SDF-1 And
CXCR4 In Normal And Malignant
Hematopoiesis. Histology and Histopathology:
cellular and molecular biology, 19(1), 299-309.
2003
Bendall, L., James, A., Zannettino, A., Simmons,
P., Gottlieb, D., Bradstock, K. (2003). A novel
CD44 antibody identifies an epitope that is
aberrantly expressed on acute lymphoblastic
leukaemia cells. Immunology and Cell Biology,
81(4), 311-319.
Nilsson, S., Johnston, H., Whitty, G., Williams,
B., Webb, R., Denhardt, D., Bertoncello, I.,
Bendall, L., Simmons, P., Haylock, D. (2005).
Osteopontin, a key component of the
hematopoietic stem cell niche and regulator
Lévesque, J., Hendy, J., Takamatsu, Y.,
Simmons, P., Bendall, L. (2003). Disruption of
the CXCR4/CXCL12 chemotactic interaction
during hematopoietic stem cell mobilization
induced by GCSF or cyclophosphamide. Journal
of Clinical Investigation, 111(2), 187-196.
of primitive hematopoietic progenitor cells.
Blood, 106(4), 1232-1239. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15845900">[More Information]</a>
Juarez, J., Gottlieb, D., Bradstock, K., Bendall,
L. (2003). Effects of inhibitors of the chemokine
receptor CXCR4 on acute lymphoblastic
leukemia cells in vitro. Leukemia, 17(7),
1294-1300.
Shaw, S., Haylock, D., Lock, R., Bendall, L.,
Simmons, P., Johnston, H., Fletcher, K., Webb,
R., Brown, T., Liem, N., et al (2005). The role of
hyaluronic acid in normal and perturbed
hemopoietic stem cell biology. In E.A. Balazs
and V.C. Hascall (Eds.), Hyaluronan: Structure,
Metabolism, Biological Activities, Therapeutic
Applications, (pp. 293-299). New Jersey: Matrix
Biology Inst.
Zannettino, A., Roubelakis, M., Welldon, K.,
Jackson, D., Simmons, P., Bendall, L., Henniker,
A., Harrison, K., Niutta, S., Bradstock, K., et al
(2003). Novel mesenchymal and haematopoietic
cell isoforms of the SHP-2 docking receptor,
PZR: identification, molecular cloning and
effects on cell migration. Biochemical Journal,
370(2), 537-549.
Khan, N., Bradstock, K., Bendall, L. (2005). The
Saad, S., Gottlieb, D., Bradstock, K., Overall, C.,
2002
Publications for Linda Bendall
Bendall, L. (2002). Cancer cell-associated
fibronectin induces release of matrix
metalloproteinase-2 from normal fibroblasts.
Cancer Research, 62, 283-289.
2001
McQibban,, G., Butler,, G., Gong,, J., Bendall,
L., Power, C., Clark-Lewis, I., Overall, M.
(2001). Matrix metalloproteinase activity
inactivates the CXC chemokine stromal
cell-derived factor-1. Journal of Biological
Chemistry, 276(47), 43503-43508.
Shen, W., Bendall, L., Gottlieb, D., Bradstock,
K. (2001). The chemokine receptor CXCR4
enhances integrin mediated in vitro adhesion and
facilitates engraftment of leukemic precursor-B
cells in the bone marrow. Experimental
Hematology, 29(12), 1439-1447.
2000
Bendall, L., Bradstock, K., Gottlieb, D. (2000).
Expression of CD44 variant exons in acute
myeloid leukemia is more common and more
complex than that observed in normal blood,
bone marrow or CD34+ cells. Leukemia, 14(7),
1239-1246.
Gu, B., Zhang, W., Bendall, L., Chessell, I.,
Buell, G., Wiley, J. (2000). Expression of
P2X(7) purinoceptors on human lymphocytes
and monocytes: evidence for nonfunctional
P2X(7) receptors. American Journal of
Physiology: Cell Physiology, 279(4),
C1189-C1197.
Saad, S., Bendall, L., James, A., Gottlieb, D.,
Bradstock, K. (2000). Induction of matrix
metalloproteinases MMP-1 and MMP-2 by
co-culture of breast cancer cells and bone
marrow fibroblasts. Breast Cancer Research and
Treatment, 63(2), 105-115.