Publications for Jeff Holst Publications for Jeff Holst 2016 Xi, Z., Yao, M., Li, Y., Holst, J., Liu, T., Cai, S., Lao, Y., Tan, H., Xu, H., Dong, Q. (2016). Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation. Cell Death and Disease, 7(6), 1-13. <a href="http://dx.doi.org/10.1038/cddis.2016.123" >[More Information]</a> Wong, J., Au, A., Gao, D., Pinello, N., Kwok, C., Thoeng, A., Lau, K., Gordon, J., Schmitz, U., Feng, Y., Nguyen, T., Middleton, R., Bailey, C., Holst, J., Rasko, J., Ritchie, W. (2016). RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever. Nucleic Acids Research, 44(6), 2888-2897. <a href="http://dx.doi.org/10.1093/nar/gkw041">[ More Information]</a> 2015 Wang, K., Holst, J. (2015). L-type amino acid transport and cancer: targeting the mTORC1 pathway to inhibit neoplasia. American Journal of Cancer Research, 5(4), 1281-1294. Grkovic, T., Pouwer, R., Wang, K., Guymer, G., Holst, J., Quinn, R. (2015). LAT Transport Inhibitors from Pittosporum venulosum Identified by NMR Fingerprint Analysis. Journal of Natural Products, 78(6), 1215-1220. <a href="http://dx.doi.org/10.1021/np500968t">[M ore Information]</a> Colas, C., Grewer, C., Otte, N., Gameiro, A., Albers, T., Singh, K., Shere, H., Bonomi, M., Holst, J., Schlessinger, A. (2015). Ligand Discovery for the Alanine-SerineCysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening. PLoS Computational Biology, 11(10), 1-22. <a href="http://dx.doi.org/10.1371/journal.pcbi.100 4477">[More Information]</a> Hnit, S., Xie, C., Yao, M., Holst, J., Bensoussan, A., de Souza, P., Li, Z., Dong, Q. (2015). p27(Kip1) signaling: Transcriptional and post-translational regulation. The International Journal of Biochemistry and Cell Biology, 68, 9-14. <a href="http://dx.doi.org/10.1016/j.biocel.2015.08. 005">[More Information]</a> Leach, D., Need, E., Toivanen, R., Trotta, A., Palenthorpe, H., Tamblyn, D., Kopsaftis, T., England, G., Smith, E., Drew, P., Holst, J., et al (2015). Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome. Oncotarget, 6(18), 16135-16150. Wang, K., Hardie, R., Hoy, A., van Geldermalsen, M., Gao, D., Fazli, L., Sadowski, M., Balaban, S., Schreuder, M., Nagarajah, R., Wong, J., Metierre, C., Pinello, N., Otte, N., Bailey, C., Ritchie, W., Rasko, J., Holst, J., et al (2015). Targeting ASCT2-Mediated Glutamine Uptake Blocks Prostate Cancer Growth and Tumour Development. Journal of Pathology, 236(3), 278-289. <a href="http://dx.doi.org/10.1002/path.4518">[Mo re Information]</a> Yao, M., Xie, C., Kiang, M., Teng, Y., Harman, D., Tiffen, J., Wang, K., Sved, P., Bao, B., Witting, P., Holst, J., Dong, Q. (2015). Targeting of cytosolic phospholipase A2a impedes cell cycle re-entry of quiescent prostate cancer cells. Oncotarget, 6(33), 34458-34474. <a href="http://dx.doi.org/10.18632/oncotarget.527 7">[More Information]</a> 2014 Wong, J., Ritchie, W., Gao, D., Lau, K., Gonzalez, M., Choudhary, A., Taft, R., Rasko, J., Holst, J. (2014). Identification of nuclear-enriched miRNAs during mouse granulopoiesis. Journal of Hematology & Oncology, 7(1), 1-15. <a href="http://dx.doi.org/10.1186/1756-8722-7-42" >[More Information]</a> Wang, K., Grkovic, T., Font Sadurni, J., Bonham, S., Pouwer, R., Bailey, C., Moran, A., Ryan, R., Rasko, J., Jormakka, M., Holst, J., et al (2014). Monoterpene Glycoside ESK246 from Pittosporum Targets LAT3 Amino Acid Transport and Prostate Cancer Cell Growth. ACS Chemical Biology, 9(6), 1369-1376. <a href="http://dx.doi.org/10.1021/cb500120x">[M ore Information]</a> Wang, K., Beaumont, K., Otte, N., Font Sadurni, J., Bailey, C., van Geldermalsen, M., Sharp, D., Tiffen, J., Ryan, R., Jormakka, M., Haass, N., Rasko, J., Holst, J. (2014). Targeting glutamine transport to suppress melanoma cell growth. International Journal of Cancer, 135(5), 1060-1071. <a href="http://dx.doi.org/10.1002/ijc.28749">[Mor e Information]</a> 2013 Holst, J. (2013). Letter to the Editor. International Journal of Pharmaceutics, 455(1-2), 393-393. <a href="http://dx.doi.org/10.1016/j.ijpharm.2013.0 7.008">[More Information]</a> Wong, J., Ritchie, W., Ebner, O., Selbach, M., Wong, J., Huang, Y., Gao, D., Pinello, N., Gonzalez, M., Baidya, K., Thoeng, A., Khoo, T., Bailey, C., Holst, J., Rasko, J. (2013). Orchestrated Intron Retention Regulates Normal Publications for Jeff Holst Granulocyte Differentiation. Cell, 154(3), 583-595. <a href="http://dx.doi.org/10.1016/j.cell.2013.06.05 2">[More Information]</a> Khoo, T., Xiros, N., Guan, F., Orellana, D., Holst, J., Joshua, D., Rasko, J. (2013). Performance evaluation of the Abbott CELL-DYN Emerald for use as a bench-top analyzer in a research setting. International Journal of Laboratory Hematology, 35(4), 447-456. <a href="http://dx.doi.org/10.1111/ijlh.12040">[Mo re Information]</a> Wang, K., Tiffen, J., Bailey, C., Lehman, M., Ritchie, W., Fazli, L., Metierre, C., Feng, Y., Li, E., Gleave, M., Rasko, J., Holst, J., et al (2013). Targeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor Development. Journal of the National Cancer Institute, 105(19), 1463-1473. <a href="http://dx.doi.org/10.1093/jnci/djt241">[M ore Information]</a> Tiffen, J., Bailey, C., Marshall, A., Metierre, C., Feng, Y., Wang, K., Watson, S., Holst, J., Rasko, J. (2013). The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells. International Journal of Cancer, 133(7), 1603-1614. <a href="http://dx.doi.org/10.1002/ijc.28184">[Mor e Information]</a> 2012 de Bock, C., Ardjmand, A., Molloy, T., Bone, S., Johnstone, D., Campbell, D., Shipman, K., Yeadon, T., Holst, J., Spanevello, M., Catchpoole, D., et al (2012). The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia. Leukemia, 26(5), 918-926. <a href="http://dx.doi.org/10.1038/leu.2011.319">[ More Information]</a> 2011 Wang, Q., Bailey, C., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M., Hendy, S., Buchanan, G., Nelson, C., Rasko, J., Holst, J. (2011). Androgen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer Progression. Cancer Research, 71(24), 7525-7536. <a href="http://dx.doi.org/10.1158/0008-5472.CAN -11-1821">[More Information]</a> Broer, A., Juelich, T., Vanslambrouck, J., Tietze, N., Solomon, P., Holst, J., Bailey, C., Rasko, J., Broer, S. (2011). Impaired Nutrient Signaling and Body Weight Control in a Na+ Neutral Amino Acid Cotransporter (Slc6a19)-deficient Mouse. Journal of Biological Chemistry, 286(30), 26638-26651. <a href="http://dx.doi.org/10.1074/jbc.M111.24132 3">[More Information]</a> 2010 Tiffen, J., Bailey, C., Ng, C., Rasko, J., Holst, J. (2010). Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo. Molecular Cancer, 9, 299-1-299-8. <a href="http://dx.doi.org/10.1186/1476-4598-9-29 9">[More Information]</a> Flamant, S., Ritchie, W., Guilhot, J., Holst, J., Bonnet, M., Chomel, J., Guilhot, F., Turhan, A., Rasko, J. (2010). Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia. Haematologica, 95(8), 1325-1333. <a href="http://dx.doi.org/10.3324/haematol.2009.0 20636">[More Information]</a> Taft, R., Simons, C., Nahkuri, S., Oey, H., Korbie, D., Mercer, T., Holst, J., Ritchie, W., Wong, J., Rasko, J., et al (2010). Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans. Nature Structural and Molecular Biology, 17(8), 1030-1035. <a href="http://dx.doi.org/10.1038/nsmb.1841">[M ore Information]</a> Kranias, G., Watt, L., Carpenter, H., Holst, J., Ludowyke, R., Strack, S., Sim, A., Verrills, N. (2010). Protein Phosphatase 2A Carboxymethylation and Regulatory B Subunits Differentially Regulate Mast Cell Degranulation. Cellular Signalling, 22(12), 1882-1890. <a href="http://dx.doi.org/10.1016/j.cellsig.2010.07. 017">[More Information]</a> Broer, A., Vanslambrouck, J., Thavyogarajah, T., Holst, J., Bailey, C., Broer, S., Rasko, J. (2010). Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria. Biochemical Journal, 428(3), 397-407. <a href="http://dx.doi.org/10.1042/BJ20091667">[ More Information]</a> Holst, J., Watson, S., Lord, M., Eamegdool, S., Bax, D., Nivison-Smith, L., Kondyurin, A., Ma, L., Oberhauser, A., Weiss, A., Rasko, J. (2010). Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells. Nature Biotechnology, 28(10), 1123-1128. <a href="http://dx.doi.org/10.1038/nbt.1687">[Mor e Information]</a> Wang, H., Holst, J., Woo, S., Guy, C., Bettini, M., Wang, Y., Shafer, A., Naramura, M., Publications for Jeff Holst Mingueneau, M., Dragone, L., et al (2010). Tonic Ubiquitylation Controls T-cell Receptor:CD3 Complex Expression During T-cell Development. The EMBO Journal, 29(7), 1285-1298. <a href="http://dx.doi.org/10.1038/emboj.2010.10" >[More Information]</a> 2008 Holst, J., Wang, H., Eder, K., Workman, C., Boyd, K., Baquet, Z., Singh, H., Forbes, K., Chruscinski, A., Smeyne, R., et al (2008). Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity. Nature Immunology, 9(6), 658-666. <a href="http://dx.doi.org/10.1038/ni.1611">[More Information]</a> 2007 El Kasmi, K., Holst, J., Coffre, M., Mielke, L., de Pauw, A., Lhocine, N., Smith, A., Rutschman, R., Kaushal, D., Shen, Y., et al (2007). General nature of the STAT3-activated anti-inflammatory response. The Journal of Immunology, 177(11), 7880-7888. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17114459">[More Information]</a> Holst, J., Szymczak-Workman, A., Vignali, K., Burton, A., Workman, C., Vignali, D. (2007). Generation of T-cell receptor retrogenic mice. Nature Protocols, 1(1), 406-417. <a href="http://dx.doi.org/10.1038/nprot.2006.61">[ More Information]</a> 2006 Holst, J., Vignali, K., Burton, A., Vignali, D. (2006). Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice. Nature Methods, 3(3), 191-197. <a href="http://dx.doi.org/10.1038/nmeth858">[Mo re Information]</a> Holst, J., Rasko, J. (2006). The Use of Retroviral Vectors for Gene Transfer into Hematopoietic Stem Cells. Methods in Enzymology, 420, 82-100. <a href="http://dx.doi.org/10.1016/S0076-6879(06) 20006-5">[More Information]</a> Holst, J., Rasko, J. (2006). The use of retroviral vectors for gene transfer into hematopoietic stem cells. Methods in Enzymology, 420, 82-100. <a href="http://dx.doi.org/10.1016/S0076-6879(06) 20006-5">[More Information]</a>