Publications for Anthony Ashton Publications for Anthony Ashton 2015 Harkness, L., Ashton, A., Burgess, J. (2015). Asthma is not only an airway disease, but also a vascular disease. Pharmacology & Therapeutics, 148(C), 17-33. <a href="http://dx.doi.org/10.1016/j.pharmthera.201 4.11.010">[More Information]</a> Schneuer, F., Nassar, N., Guilbert, C., Tasevski, V., Ashton, A., Morris, J., Roberts, C. (2015). Evaluation of first trimester serum soluble endothelial cell-specific tyrosine kinase receptor in normal and affected pregnancies. The Journal of Maternal-Fetal & Neonatal Medicine, 28(15), 1815-1821. <a href="http://dx.doi.org/10.3109/14767058.2014. 969233">[More Information]</a> McKelvey, K., Powell, K., Ashton, A., Morris, J., McCracken, S. (2015). Exosomes: Mechanisms of Uptake. Journal of Circulating Biomarkers, 4(7), 1-9. <a href="http://dx.doi.org/10.5772/61186">[More Information]</a> Morton, S., Chaston, D., Howitt, L., Heisler, J., Nicholson, B., Fairweather, S., Broer, S., Ashton, A., Matthaei, K., Hill, C. (2015). Loss of functional endothelial connexin40 results in exercise-induced hypertension in mice. Hypertension, 65(3), 662-669. <a href="http://dx.doi.org/10.1161/HYPERTENSIO NAHA.114.04578">[More Information]</a> Ashton, A., Le, T., Gomez-Sanchez, C., Morel-Kopp, M., McWhitney, B., Hudson, A., Mihailidou, A. (2015). Role of Nongenomic Signaling Pathways Activated by Aldosterone During Cardiac Reperfusion Injury. Molecular Endocrinology, 29(8), 1144-1155. <a href="http://dx.doi.org/10.1210/ME.2014-1410" >[More Information]</a> Mukherjee, S., Mukhopadhyay, A., Andriani, G., Machado, F., Ashton, A., Huang, H., Weiss, L., Tanowitz, H. (2015). Trypanosoma cruzi invasion is associated with trogocytosis. Microbes and Infection, 17, 62-70. <a href="http://dx.doi.org/10.1016/j.micinf.2014.10. 009">[More Information]</a> 2014 Schneuer, F., Roberts, C., Ashton, A., Guilbert, C., Tasevski, V., Morris, J., Nassar, N. (2014). Angiopoietin 1 and 2 serum concentrations in first trimester of pregnancy as biomarkers of adverse pregnancy outcomes. American Journal of Obstetrics & Gynecology, 210(4), 345 e1-345 e9. <a href="http://dx.doi.org/10.1016/j.ajog.2013.11.0 12">[More Information]</a> Mihailidou, A., Ashton, A. (2014). Cardiac effects of aldosterone: Does gender matter? Steroids, 91(C), 32-37. <a href="http://dx.doi.org/10.1016/j.steroids.2014.0 8.013">[More Information]</a> Schneuer, F., Roberts, C., Guilbert, C., Simpson, J., Algert, C., Khambalia, A., Tasevski, V., Ashton, A., Morris, J., Nassar, N. (2014). Effects of maternal serum 25-hydroxyvitamin D concentrations in the first trimester on subsequent pregnancy outcomes in an Australian population. The American Journal of Clinical Nutrition, 99(2), 287-295. <a href="http://dx.doi.org/10.3945/ajcn.113.065672 ">[More Information]</a> Le, T., Ashton, A., Mardini, M., Stanton, P., Funder, J., Handelsman, D., Mihailidou, A. (2014). Role of Androgens in Sex Differences in Cardiac Damage During Myocardial Infarction. Endocrinology, 155(2), 568-575. <a href="http://dx.doi.org/10.1210/en.2013-1755">[ More Information]</a> 2013 Schneuer, F., Nassar, N., Guilbert, C., Tasevski, V., Ashton, A., Morris, J., Roberts, C. (2013). First trimester screening of serum soluble fms-like tyrosine kinase-1 and placental growth factor predicting hypertensive disorders of pregnancy. Pregnancy Hypertension: an international journal of women's cardiovascular health, 3(4), 215-221. <a href="http://dx.doi.org/10.1016/j.preghy.2013.04 .119">[More Information]</a> Mukherjee, S., Sadekar, N., Ashton, A., Huang, H., Spray, D., Lisanti, M., Machado, F., Weiss, L., Tanowitz, H. (2013). Identification of a functional prostanoid-like receptor in the protozoan parasite, Trypanosoma cruzi. Parasitology Research, 112(4), 1417-1425. <a href="http://dx.doi.org/10.1007/s00436-012-327 1-5">[More Information]</a> Chaston, D., Baillie, B., Grayson, T., Courjaret, R., Heisler, J., Lau, K., Machaca, K., Nicholson, B., Ashton, A., Matthaei, K., et al (2013). Polymorphism in endothelial connexin40 enhances sensitivity to intraluminal pressure and increases arterial stiffness. Arteriosclerosis, Thrombosis, and Vascular Biology, 33(5), 962-970. <a href="http://dx.doi.org/10.1161/ATVBAHA.112. 300957">[More Information]</a> Mihailidou, A., Ritchie, R., Ashton, A. (2013). Sex Differences in Sudden Cardiac Death. In David Gaze (Eds.), Ischemic Heart Disease, (pp. 61-75). Croatia: InTech Publishers. 2012 Schneuer, F., Nassar, N., Khambalia, A., Publications for Anthony Ashton Tasevski, V., Ashton, A., Morris, J., Roberts, C. (2012). First trimester screening of maternal placental protein 13 for predicting preeclampsia and small for gestational age: In-house study and systematic review. Placenta, 33(9), 735-740. <a href="http://dx.doi.org/10.1016/j.placenta.2012.0 5.012">[More Information]</a> Le, T., Mardini, M., Howell, V., Funder, J., Ashton, A., Mihailidou, A. (2012). Low-dose spironolactone prevents apoptosis repressor with caspase recruitment domain degradation during myocardial infarction. Hypertension, 59(6), 1164-1169. <a href="http://dx.doi.org/10.1161/HYPERTENSIO NAHA.111.190488">[More Information]</a> Lisanti, M., Machado, F., Weiss, L., Mukherjee, S. (2011). Microarray analysis of the mammalian thromboxane receptor-Trypanosoma cruzi interaction. Cell Cycle, 10(7), 1132-1143. <a href="http://dx.doi.org/10.4161/cc.10.7.15207">[ More Information]</a> Hadfield, K., McCracken, S., Ashton, A., Nguyen, T., Morris, J. (2011). Regulated suppression of NF-kB throughout pregnancy maintains a favourable cytokine environment necessary for pregnancy success. Journal of Reproductive Immunology, 89(1), 1-9. <a href="http://dx.doi.org/10.1016/j.jri.2010.11.008 ">[More Information]</a> Woolnough, C., Wang, Y., Kan, C., Morris, J., Tasevski, V., Ashton, A. (2012). Source of angiopoietin-2 in the sera of women during pregnancy. Microvascular research, 84(3), 367-374. <a href="http://dx.doi.org/10.1016/j.mvr.2012.08.00 3">[More Information]</a> Nassar, N., Halligan, G., Roberts, C., Morris, J., Ashton, A. (2011). Systematic review of first-trimester vitamin D normative levels and outcomes of pregnancy. American Journal of Obstetrics & Gynecology, 205(3), 208.e1-208.e7. <a href="http://dx.doi.org/10.1016/j.ajog.2011.03.0 58">[More Information]</a> Gavrilov, S., Nuhrenberg, T., Ashton, A., Peng, C., Moore, J., Konstantinidis, K., Mummery, C., Kitsis, R. (2012). Tbx6 is a determinant of cardiac and neural cell fate decisions in multipotent P19CL6 cells. Differentiation, 84(2), 176-184. <a href="http://dx.doi.org/10.1016/j.diff.2012.04.00 7">[More Information]</a> Ekambaram, P., Lambiv, W., Cazzolli, R., Ashton, A., Honn, K. (2011). The thromboxane synthase and receptor signaling pathway in cancer: an emerging paradigm in cancer progression and metastasis. Cancer and Metastasis Reviews, 30(3-4), 397-408. <a href="http://dx.doi.org/10.1007/s10555-011-929 7-9">[More Information]</a> 2011 2010 Mukherjee, S., Machado, F., Huang, H., Oz, H., Jelicks, L., Prado, C., Koba, W., Fine, E., Zhao, D., Factor, S., Ashton, A., et al (2011). Aspirin treatment of mice infected with Trypanosoma cruzi and implications for the pathogenesis of Chagas disease. PloS One, 6(2), e16959-1-e16959-10. <a href="http://dx.doi.org/10.1371/journal.pone.001 6959">[More Information]</a> Rand, J., Wu, X., Quinn, A., Ashton, A., Chen, P., Hathcock, J., Andree, H., Taatjes, D. (2010). Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drug. Blood, 115(11), 2292-2299. <a href="http://dx.doi.org/10.1182/blood-2009-04-2 13520">[More Information]</a> Machado, F., Mukherjee, S., Weiss, L., Tanowitz, H., Ashton, A. (2011). Bioactive Lipids in Trypanosoma cruzi Infection. In Louis M. Weiss and Herbert B. Tanowitz (Eds.), Advances in Parasitology (Volume 76): Chagas Disease, Part B, (pp. 1-31). London: Academic Press. 2009 Jacobs, M., Nassar, N., Roberts, C., Hadfield, R., Morris, J., Ashton, A. (2011). Levels of soluble fms-like tyrosine kinase one in first trimester and outcomes of pregnancy: a systematic review. Reproductive Biology and Endocrinology, 9(June), 77-1-77-8. <a href="http://dx.doi.org/10.1186/1477-7827-9-77" >[More Information]</a> Tanowitz, H., Mukhopadhyay, A., Ashton, A., Villalta, F., Scharfstein, J., Ashton, A., Tyler, K., Guan, F., Mukherjee, S., Lima, M., Alvarez, S., Weiss, L., Huang, H., et al (2009). Perspectives on the Trypanosoma cruzi-host cell receptor interactions. Parasitology Research, 104(6), 1251-1260. <a href="http://dx.doi.org/10.1007/s00436-009-138 3-3">[More Information]</a> 2008 Moussa, O., Ashton, A., Fraig, M., Garrett-Mayer, E., Ghoneim, M., Halushka, P., Watson, D. (2008). Novel Role of Thromboxane Receptors β Isoform in Bladder Cancer Pathogenesis. Cancer Research, 68(11), 4097-4104. <a Publications for Anthony Ashton href="http://dx.doi.org/10.1158/0008-5472.CAN -07-6560">[More Information]</a> 2007 Muehlbauer, S., Evering, T., Bonuccelli, G., Squires, R., Ashton, A., Porcelli, S., Lisanti, M., Brojatsch, J., Brojatsch, J. (2007). Anthrax lethal toxin kills macrophages in a strain-specific manner by apoptosis or caspase-1-mediated necrosis. Cell Cycle, 6(6), 758-766. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17374996">[More Information]</a> Zembala, M., Wilczek, P., Kwiatkowski, P., Ashton, A. (2007). Myocardial regeneration – the revolution continues. Kardiochirurgia i Torakochirurgia Polska, 4(3), 239-245. Foo, R., Nam, Y., Ostreicher, M., Metzl, M., Whelan, R., Peng, C., Ashton, A., Fu, W., Mani, K., Chin, S., et al (2007). Regulation of p53 tetramerization and nuclear export by ARC. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 104(52), 20826-20831. <a href="http://dx.doi.org/10.1073/pnas.071001710 4">[More Information]</a> Nam, Y., Mani, K., Wu, L., Peng, C., Calvert, J., Foo, R., Krishnamurthy, B., Miao, W., Ashton, A., Lefer, D., et al (2007). The apoptosis inhibitor ARC undergoes ubiquitin-proteasomal-mediated degradation in response to death stimuli: identification of a degradation-resistant mutant. Journal of Biological Chemistry, 282(8), 5522-5528. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17142452">[More Information]</a> Ashton, A., Mukherjee, S., Nagajyothi, F., Huang, H., Braunstein, V., Desruisseaux, M., Factor, S., Lopez, L., Berman, J., Wittner, M., et al (2007). Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection. The Journal of Experimental Medicine, 204(4), 929-940. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17420269">[More Information]</a> 2006 Ashton, A., D'Alessandro, D., Michler, E. (2006). Use of skeletal myoblasts for the treatment of CHF. In Marc S Penn (Eds.), Stem Cells and Myocardial, (pp. 259-276). United States: Humana Press. 2005 Mercier, I., Vuolo, M., Madan, R., Xue, X., Levalley, A., Ashton, A., Jasmin, J., Czaja, M., Lin, E., Armstrong, R., et al (2005). ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance. Cell Death and Differentiation, 12(6), 682-686. <a href="http://dx.doi.org/10.1038/sj.cdd.4401631" >[More Information]</a> Colombo, P., Banchs, J., Celaj, S., Talreja, A., Lachmann, J., Malla, S., DuBois, N., Ashton, A., Latif, F., Jorde, U., et al (2005). Endothelial cell activation in patients with decompensated heart failure. Circulation, 111(1), 58-62. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=15611373">[More Information]</a> Ashton, A., Duffy, H., Iacobas, I., Spray, D. (2005). Using antibody arrays to detect protein-protein interactions in connexins. In Stefan Dhein, Friedrich Wilhelm Mohr & Mario Delmar (Eds.), Practical Methods in Cardiovascular Research, (pp. 916-935). United States of America: Springer. 2004 Nam, Y., Mani, K., Ashton, A., Peng, C., Krishnamurthy, B., Hayakawa, Y., Lee, P., Korsmeyer, S., Kitsis, R. (2004). Inhibition of Both the Extrinsic and Intrinsic Death Pathways through Nonhomotypic Death-Fold Interactions. Molecular Cell, 15(6), 901-912. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=15383280">[More Information]</a> Duffy, H., Ashton, A., O'Donnell, P., Coombs, W., Taffet, S., Delmar, M., Spray, D. (2004). Regulation of connexin43 protein complexes by intracellular acidification. Circulation Research, 94(2), 215-222. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=14699011">[More Information]</a> Ashton, A., Cheng, Y., Helisch, A., Ware, J. (2004). Thromboxane A2 Receptor Agonists Antagonize the Proangiogenic Effects of Fibroblast Growth Factor-2:Role of Receptor Internalization, Thrombospondin-1, and αvβ3. Circulation Research, 94(6), 735-742. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=14963009">[More Information]</a> Ashton, A., Ware, J. (2004). Thromboxane A2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migration. Circulation Research, 95(4), 372-379. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract Publications for Anthony Ashton &list_uids=15242977">[More Information]</a> 2003 Woodman, S., Ashton, A., Schubert, W., Lee, H., Williams, T., Medina, F., Wyckoff, J., Combs, T., Lisanti, M. (2003). Caveolin-1 knockout mice show an impaired angiogenic response to exogenous stimuli. The American Journal of Pathology, 162(6), 2059-2068. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=12759260">[More Information]</a> Neumeister, P., Pixley, F., Xiong, Y., Xie, H., Wu, K., Ashton, A., Cammer, M., Chan, A., Symons, M., Stanley, E., et al (2003). Cyclin D1 governs adhesion and motility of macrophages. Molecular Biology of the Cell, 14(5), 2005-2015. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=12802071">[More Information]</a> Ashton, A., Ware, G., Kaul, D., Ware, J. (2003). Inhibition of tumor necrosis factor alpha-mediated NFkappaB activation and leukocyte adhesion, with enhanced endothelial apoptosis, by G protein-linked receptor (TP) ligands. Journal of Biological Chemistry, 278(14), 11858-11866. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=12517920">[More Information]</a> Hotchkiss, K., Ashton, A., Klein, R., Lenzi, M., Zhu, G., Schwartz, E. (2003). Mechanisms by Which Tumor Cells and Monocytes Expressing the Angiogenic Factor Thymidine Phosphorylase Mediate Human Endothelial Cell Migration. Cancer Research, 63(2), 527-533. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=12543812">[More Information]</a> Ma, H., Calderon, T., Kessel, T., Ashton, A., Berman, J. (2003). Mechanisms of hepatocyte growth factor-mediated vascular smooth muscle cell migration. Circulation Research, 93(11), 1066-1073. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=14576199">[More Information]</a> Hotchkiss, K., Ashton, A., Schwartz, E. (2003). Thymidine phosphorylase and 2-deoxyribose stimulate human endothelial cell migration by specific activation of the integrins alpha 5 beta 1 and alpha V beta 3. Journal of Biological Chemistry, 278(21), 19272-19279. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=12639965">[More Information]</a> 2002 Mani, K., Ashton, A., Kitsis, R. (2002). Taking the BAD out of Adrenergic Stimulation. Journal of Molecular and Cellular Cardiology, 34, 709-712.