Publications for W. Bret Church Publications for W. Bret Church 2016 Nematollahi, A., Sun, G., Jayawickrama, G., Church, W. (2016). Kynurenine aminotransferase isozyme inhibitors: A review. International Journal of Molecular Sciences, 17(6), 1-22. <a href="http://dx.doi.org/10.3390/ijms17060946"> [More Information]</a> Nematollahi, A., Sun, G., Harrop, S., Hanrahan, J., Church, W. (2016). Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 A Resolution. International Journal of Molecular Sciences, 17(4), 1-11. <a href="http://dx.doi.org/10.3390/ijms17040446"> [More Information]</a> 2015 Lynch, G., Portelli, S., Church, W. (2015). Composite Model of Full GP Structure of Ebola Virus Envelope Glycoprotein. Journal of Molecular and Genetic Medicine, 9, 1-4. <a href="http://dx.doi.org/10.4172/1747-0862.1000/ 101">[More Information]</a> Jayawickrama, G., Sadig, R., Sun, G., Nematollahi, A., Nadvi, N., Hanrahan, J., Gorrell, M., Church, W. (2015). Kynurenine aminotransferases and the prospects of inhibitors for the treatment of schizophrenia. Current Medicinal Chemistry, 22(24), 2902-2918. <a href="http://dx.doi.org/10.2174/0929867322666 150608094054">[More Information]</a> Kim, E., Rath, E., Tsang, V., Duff, A., Robinson, B., Church, W., Benn, D., Dwight, T., Clifton-Bligh, R. (2015). Structural and functional consequences of succinate dehydrogenase subunit B mutations. Endocrine-Related Cancer, 22(3), 387-397. <a href="http://dx.doi.org/10.1530/ERC-15-0099">[ More Information]</a> 2014 Nematollahi, A., Aminimoghadamfarouj, N., Church, W. (2014). Essential structural features of novel antischizophrenic drugs: a review. Medicinal Chemistry, 10(6), 541-549. <a href="http://dx.doi.org/10.2174/1573406410666 131229150746">[More Information]</a> Nematollahi, A., Church, W., Nadvi, N., Gorrell, M., Sun, G. (2014). Homology Modeling of Human Kynurenine Aminotransferase III and Observations on Inhibitor Binding Using Molecular Docking. Central Nervous System Agents in Medicinal Chemistry, 14(1), 2-9. <a href="http://dx.doi.org/10.2174/1871524914666 140416095523">[More Information]</a> Tessier, D., Laroum, S., Duval, B., Rath, E., Church, W., Hao, J. (2014). In silico evaluation of the influence of the translocon on partitioning of membrane segments. BMC Bioinformatics, 15(156). <a href="http://dx.doi.org/10.1186/1471-2105-15-1 56">[More Information]</a> Rath, E., Duff, A., Håkansson, A., Knott, R., Church, W. (2014). Small-angle X-ray scattering of BAMLET at pH 12: A complex of α-lactalbumin and oleic acid. Proteins: Structure, Function, and Bioinformatics, 82(7), 1400-1408. <a href="http://dx.doi.org/10.1002/prot.24508">[M ore Information]</a> Lee, H., Lee, H., Lee, L., Teber, E., Church, W. (2014). The use of soluble protein structures in modeling helical proteins in a layered membrane. Journal of Biomolecular Structure & Dynamics, 32(2), 308-318. <a href="http://dx.doi.org/10.1080/07391102.2013. 765808">[More Information]</a> 2013 Rath, E., Tessier, D., Campbell, A., Lee, H., Werner, T., Salam, N., Lee, L., Church, W. (2013). A benchmark server using high resolution protein structure data, and benchmark results for membrane helix predictions. BMC Bioinformatics, 14(1), 1-11. <a href="http://dx.doi.org/10.1186/1471-2105-14-1 11">[More Information]</a> Zhou, F., Zheng, J., Zhu, L., Jodal, A., Cui, P., Wong, K., Gurney, H., Church, W., Murray, M. (2013). Functional Analysis of Novel Polymorphisms in the Human SLCO1A2 Gene that Encodes the Transporter OATP1A2. The AAPS Journal, 15(4), 1099-1108. <a href="http://dx.doi.org/10.1208/s12248-013-951 5-1">[More Information]</a> Werner, T., Church, W. (2013). Kink characterization and modeling in transmembrane protein structures. Journal of Chemical Information and Modeling, 53(11), 2926-2936. <a href="http://dx.doi.org/10.1021/ci400236s">[Mo re Information]</a> Hamzeh-Mivehroud, M., Alizadeh, A., Morris, M., Church, W., Dastmalchi, S. (2013). Phage display as a technology delivering on the promise of peptide drug discovery. Drug Discovery Today, 18(23-24), 1144-1157. <a href="http://dx.doi.org/10.1016/j.drudis.2013.09. 001">[More Information]</a> Lee, L., Bryant, K., Bouveret, R., Lei, P., Duff, A., Harrop, S., Huang, E., Harvey, R., Gelb, M., Gray, P., Church, W., et al (2013). Selective Inhibition of Human Group IIA-secreted Publications for W. Bret Church Phospholipase a 2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes. Journal of Biological Chemistry, 288(21), 15269-15279. <a href="http://dx.doi.org/10.1074/jbc.M112.39789 3">[More Information]</a> 2012 Akladios, F., Nadvi, N., Park, J., Hanrahan, J., Kapoor, V., Gorrell, M., Church, W. (2012). Design and synthesis of novel inhibitors of human kynurenine aminotransferase-I. Bioorganic & Medicinal Chemistry Letters, 22(4), 1579-1581. <a href="http://dx.doi.org/10.1016/j.bmcl.2011.12.1 38">[More Information]</a> Lynch, G., Selleck, P., Church, W., Sullivan, J. (2012). Seasoned adaptive antibody immunity for highly pathogenic pandemic influenza in humans. Immunology and Cell Biology, 90(2), 149-158. <a href="http://dx.doi.org/10.1038/icb.2011.38">[M ore Information]</a> Werner, T., Morris, M., Dastmalchi, S., Church, W. (2012). Structural modelling and dynamics of proteins for insights into drug interactions. Advanced Drug Delivery Reviews, 64(4), 323-343. <a href="http://dx.doi.org/10.1016/j.addr.2011.11.0 11">[More Information]</a> Keane, F., Chowdhury, S., Yao, T., Nadvi, N., Gall, M., Chen, Y., Osborne, B., Ribeiro, A., Church, W., McCaughan, G., Gorrell, M., Yu, M. (2012). Targeting Dipeptidyl Peptidase-4 (DPP-4) and Fibroblast Activation Protein (FAP) for Diabetes and Cancer Therapy. In Ben Dunn (Eds.), Proteinases as Drug Targets, (pp. 118-144). Cambridge, UK: RSC Publishing. 2011 Bryant, K., Bidgood, M., Lei, P., Taberner, M., Salom, C., Kumar, V., Lee, L., Church, W., Courtenay, B., Smart, B., et al (2011). A Bifunctional Role for Group IIA Secreted Phospholipase A2 in Human Rheumatoid Fibroblast-like Synoviocyte Arachidonic Acid Metabolism. Journal of Biological Chemistry, 286(4), 2492-2503. <a href="http://dx.doi.org/10.1074/jbc.M110.12392 7">[More Information]</a> Broadhead, G., Mun, H., Avlani, V., Jourdon, O., Church, W., Christopoulos, A., Delbridge, L., Conigrave, A. (2011). Allosteric Modulation of the Calcium-sensing Receptor by y-Glutamyl Peptides Inhibition of PTH Secretion, Suppression of Intracellular cAMP Levels and A Common Mechanism of Action with L-Amino Acids. Journal of Biological Chemistry, 286(11), 8786-8797. <a href="http://dx.doi.org/10.1074/jbc.M110.14972 4">[More Information]</a> Li, N., Yun, P., Jeffries, C., Langley, D., Gamsjaeger, R., Church, W., Hunter, N., Collyer, C. (2011). The modular structure of haemagglutinin/adhesin regions in gingipains of Porphyromonas gingivalis. Molecular Microbiology, 81(5), 1358-1373. <a href="http://dx.doi.org/10.1111/j.1365-2958.201 1.07768.x">[More Information]</a> 2010 Zhou, F., Zhu, L., Cui, P., Church, W., Murray, M. (2010). Functional characterization of nonsynonymous single nucleotide polymorphisms in the human organic anion transporter 4 (hOAT4). British Journal of Pharmacology, 159, 419-427. <a href="http://dx.doi.org/10.1111/j.1476-5381.200 9.00545.x">[More Information]</a> Yu, M., Yao, T., Chowdhury, S., Nadvi, N., Osborne, B., Church, W., McCaughan, G., Gorrell, M. (2010). The dipeptidyl peptidase IV family in cancer and cell biology. The FEBS Journal, 277(5), 1126-1144. <a href="http://dx.doi.org/10.1111/j.1742-4658.200 9.07526.x">[More Information]</a> Zhang, Y., Chen, M., Church, W., Lau, K., Larkum, A., Jermiin, L. (2010). The molecular structure of the IsiA-Photosystem I supercomplex, modelled from high-resolution, crystal structures of Photosystem I and the CP43 protein. Biochimica et Biophysica Acta, 1797 (4), 457-465. <a href="http://dx.doi.org/10.1016/j.bbabio.2010.01 .002">[More Information]</a> 2009 Morris, M., Dastmalchi, S., Church, W. (2009). Rhodopsin: Structure, signal transduction and oligomerisation. The International Journal of Biochemistry and Cell Biology, 41(4), 721-724. <a href="http://dx.doi.org/10.1016/j.biocel.2008.04. 025">[More Information]</a> 2008 Dastmalchi, S., Church, W., Morris, M. (2008). Modelling the structures of G protein-coupled receptors aided by three-dimensional validation. BMC Bioinformatics, 9(S1), S14-1-S14-13. <a href="http://dx.doi.org/10.1186/1471-2105-9-S1S14">[More Information]</a> Park, J., Knott, H., Nadvi, N., Collyer, C., Wang, X., Church, W., Gorrell, M. (2008). Reversible Inactivation of Human Dipeptidyl Peptidases 8 and 9 by Oxidation. The Open Enzyme Inhibition Journal, 1, 52-60. Publications for W. Bret Church 2007 Daly, K., Church, W., Nicholas, K., Williamson, P. (2007). Comparative Modeling of Marsupial MHC Class I Molecules Identifies Structural Polymorphisms Affecting Functional Motifs. Journal of Experimental Zoology. Part A: Ecological Genetics and Physiology, 307A (11), 611-624. <a href="http://dx.doi.org/10.1002/jez.413">[More Information]</a> Dastmalchi, S., Beheshti, S., Morris, M., Church, W. (2007). Prediction of rotational orientation of transmembrane helical segments of integral membrane proteins using new environment-based propensities for amino acids derived from structural analyses. The FEBS Journal, 274(10), 2653-2660. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17451441">[More Information]</a> 2006 Teber, E., Crawford, E., Bolton, K., Van Dyk, D., Schofield, P., Kapoor, V., Church, W. (2006). Djinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration. BMC Bioinformatics, 7(33), Article 33-1-33-9. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=16426464">[More Information]</a> Lynch, G., Turville, S., Carter, B., Sloane, A., Chan, A., Muljadi, N., Li, S., Low, L., Armati, P., Raison, R., Zoellner, H., Williamson, P., Cunningham, A., Church, W. (2006). Marked differences in the structures and protein associations of lymphocyte and monocyte CD4: Resolution of a novel CD4 isoform. Immunology and Cell Biology, 84(2), 154-165. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=16519733">[More Information]</a> 2005 Lukov, L., Chawla, S., Church, W. (2005). Conditional Random Fields for Transmembrane Helix Prediction. The Ninth Pacific-Asia Conference on Knowledge Discovery and Data Mining, Berlin: Springer. 2004 Lai, P., Kaplan, W., Church, W., Wong, R. (2004). Informative 3D Visualization Of Multiple Protein Structures. Second Conference on Asia-Pacific Bioinformatics (APBC 2004), Australia: Australian Computer Society. Dastmalchi, S., Church, W., Morris, M., Iismaa, T., Mackay, J. (2004). Presence of transient helical segments in the galanin-like peptide evident from 1H NMR, circular dichroism, and prediction studies. Journal of Structural Biology, 146(3), 261-271. 2003 Shui, W., Wong, R., Graham, S., Lee, L., Church, W. (2003). A new approach to protein structure and function analysis using semi-structured databases. Journal of Research and Practice in Information Technology, 19(-), 61-69. Barry, J., Leong, G., Church, W., Issa, L., Eisman, J., Gardiner, E. (2003). Interactions of SKIP/NCoA-62, TFIIB, and Retinoid X Receptor with Vitamin D Receptor Helix H10 Residues. Journal of Biological Chemistry, 278(10), 8224-8228. 2002 Kwok, J., Kapoor, R., Gotoda, T., Iwamoto, Y., Iizuka, Y., Yamada, N., Isaacs, K., Kushwaha, V., Church, W., Schofield, P., et al (2002). A Missense Mutation in Kynurenine Aminotransferase-1 in Spontaneously Hypertensive Rats. Journal of Biological Chemistry, 277(39), 35779-35782. Dastmalchi, S., Kobus, F., Iismaa, T., Morris, M., Church, W. (2002). Comparison of the transmembrane helices of bovine rhodopsin in the crystal structure and the C α template based on cryo-electron microscopy maps and sequence analysis of the G protein-coupled receptors. Molecular Simulation, 28(8), 845-851. Church, W., Jones, K., Kuiper, D., Shine, J., Iismaa, T. (2002). Molecular modelling and site-directed mutagenesis of human GALR1 galanin receptor defines determinants of receptor subtype specificity. Protein Engineering, 15(4), 313-323. 2001 Church, W., Inglis, A., Tseng, A., Duell, R., Lei, P., Bryant, K., Scott, K. (2001). A novel approach to the design of inhibitors of human secreted phospholipase A2 based on native peptide inhibition. Journal of Biological Chemistry, 276(35), 33156-33164. Dastmalchi, S., Morris, M., Church, W. (2001). Modeling of the structural features of integral-membrane proteins using reverse-environment prediction of integral membrane protein structure (REPIMPS). Protein Science, 10(8), 1529-1538.