Publications for Jean Yang Publications for Jean Yang 2016 Jayawardana, K., Schramm, S., Tembe, V., Mueller, S., Thompson, J., Scolyer, R., Mann, G., Yang, J. (2016). Identification, Review, and Systematic Cross-Validation of microRNA Prognostic Signatures in Metastatic Melanoma. Journal of Investigative Dermatology, 136(1), 245-254. <a href="http://dx.doi.org/10.1038/JID.2015.355">[ More Information]</a> Yang, P., Humphrey, S., James, D., Yang, J., Jothi, R. (2016). Positive-unlabeled ensemble learning for kinase substrate prediction from dynamic phosphoproteomics data. Bioinformatics, 32(2), 252-259. <a href="http://dx.doi.org/10.1093/bioinformatics/bt v550">[More Information]</a> Markus, M., Yang, J., Morris, B. (2016). Transcriptome-wide targets of alternative splicing by RBM4 and possible role in cancer. Genomics, 107(4), 138-144. <a href="http://dx.doi.org/10.1016/j.ygeno.2016.02. 003">[More Information]</a> 2015 Rahman, W., Tu, T., Budzinska, M., Huang, P., Belov, L., Chrisp, J., Christopherson, R., Warner, F., Bowden, D., Thomspon, A., Bowen, D., Strasser, S., Sharland, A., Yang, J., McCaughan, G., Shackel, N., et al (2015). Analysis of Post-Liver Transplant Hepatitis C Virus Recurrence Using Serial Cluster of differentiation Antibody Microarrays. Transplantation, 99(9), e120-e126. <a href="http://dx.doi.org/10.1097/TP.00000000000 00617">[More Information]</a> Strbenac, D., Mann, G., Ormerod, J., Yang, J. (2015). ClassifyR: an R package for performance assessment of classification with applications to transcriptomics. Bioinformatics, 31(11), 1851-1853. <a href="http://dx.doi.org/10.1093/bioinformatics/bt v066">[More Information]</a> Heinemann, A., Cullinane, C., De Paoli-Iseppi, R., Wilmott, J., Gunatilake, D., Madore, J., Strbenac, D., Yang, J., Gowrishankar, K., Tiffen, J., Hersey, P., Gallagher, S., et al (2015). Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling. Oncotarget, 6(25), 21507-21521. Chaudhuri, R., Khoo, P., Tonks, K., Junutula, J., Kolumam, G., Modrusan, Z., Samocha-Bonet, D., Meoli, C., Hocking, S., Fazakerley, D., Stockli, J., Yang, J., James, D., et al (2015). Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity. Npj Systems Biology And Applications, 1, 1-10. <a href="http://dx.doi.org/10.1038/npjsba.2015.10" >[More Information]</a> Jayawardana, K., Schramm, S., Haydu, L., Thompson, J., Scolyer, R., Mann, G., Muller, S., Yang, J. (2015). Determination of prognosis in metastatic melanoma through integration of clinico-pathologic, mutation, mRNA, microRNA, and protein information. International Journal of Cancer, 136(4), 863-874. <a href="http://dx.doi.org/10.1002/ijc.29047">[Mor e Information]</a> Patrick, E., Buckley, M., Mueller, S., Lin, D., Yang, J. (2015). Inferring data-specific micro-RNA function through the joint ranking of micro-RNA and pathways from matched micro-RNA and gene expression data. Bioinformatics, 31(17), 2822-2828. <a href="http://dx.doi.org/10.1093/bioinformatics/bt v220">[More Information]</a> Yang, P., Zheng, X., Jayaswal, V., Hu, G., Yang, J., Jothi, R. (2015). Knowledge-Based Analysis for Detecting Key Signaling Events from Time-Series Phosphoproteomics Data. PLoS Computational Biology, 11(8), 1-18. <a href="http://dx.doi.org/10.1371/journal.pcbi.100 4403">[More Information]</a> Tembe, V., Schramm, S., Stark, M., Patrick, E., Jayaswal, V., Tang, Y., Barbour, A., Hayward, N., Thompson, J., Scolyer, R., Yang, J., Mann, G. (2015). microRNA and mRNA expression profiling in metastatic melanoma reveal associations with BRAF mutation and patient prognosis. Pigment Cell & Melanoma Research, 28(3), 254-226. <a href="http://dx.doi.org/10.1111/pcmr.12343">[ More Information]</a> Chaudhuri, R., Sadrieh, A., Hoffman, N., Parker, B., Humphrey, S., Stoeckli, J., Hill, A., James, D., Yang, J. (2015). PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modification. BMC Genomics, 16(1), 1-14. <a href="http://dx.doi.org/10.1186/s12864-015-182 0-x">[More Information]</a> Tiffen, J., Gunatilake, D., Gallagher, S., Gowrishankar, K., Heinemann, A., Cullinane, C., Dutton-Regester, K., Pupo, G., Strbenac, D., Yang, J., Madore, J., Mann, G., Hersey, P., et al (2015). Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes. Oncotarget, 6(29), 27023-27036. <a href="http://dx.doi.org/10.18632/oncotarget.480 9">[More Information]</a> Publications for Jean Yang Byrne, M., Koop, D., Cisternas, P., Strbenac, D., Yang, J., Wray, G. (2015). Transcriptomic analysis of Nodal- and BMP-associated genes during juvenile development of the sea urchin Heliocidaris erythrogramma. Marine Genomics, 24(1), 41-45. <a href="http://dx.doi.org/10.1016/j.margen.2015.0 5.019">[More Information]</a> 2014 Yang, P., Patrick, E., Tan, S., Fazakerley, D., Burchfield, J., Gribben, C., Prior, M., James, D., Yang, J. (2014). Direction pathway analysis of large-scale proteomics data reveals novel features of the insulin action pathway. Bioinformatics, 30(6), 808-814. <a href="http://dx.doi.org/10.1093/bioinformatics/bt t616">[More Information]</a> Palmer, S., Wong, G., Iff, S., Yang, J., Jayaswal, V., Craig, J., Rochtchina, E., Mitchell, P., Wang, J., Strippoli, G. (2014). Fluid intake and all-cause mortality, cardiovascular mortality, and kidney function: a population-based longitudinal cohort study. Nephrology, Dialysis, Transplantation, 29(7), 1377-1384. <a href="http://dx.doi.org/10.1093/ndt/gft507">[Mo re Information]</a> O'Connor, K., Parnell, G., Patrick, E., Ahlenstiel, G., Suppiah, V., van der Poorten, D., Read, S., Leung, R., Douglas, M., Yang, J., Stewart, G., Liddle, C., George, J., Booth, D. (2014). Hepatic metallothionein expression in chronic hepatitis C virus infection is IFNL3 genotype-dependent. Genes and Immunity, 15(2), 88-94. <a href="http://dx.doi.org/10.1038/gene.2013.66">[ More Information]</a> Ma, X., Yang, P., Kaplan, W., Lee, B., Wu, L., Yang, J., Yasunaga, M., Sato, K., Chisholm, D., James, D. (2014). ISL1 Regulates Peroxisome Proliferator-Activated Receptor gamma Activation and Early Adipogenesis via Bone Morphogenetic Protein 4-Dependent and -Independent Mechanisms. Molecular and Cellular Biology, 34(19), 3607-3617. <a href="http://dx.doi.org/10.1128/MCB.00583-14" >[More Information]</a> Barter, R., Schramm, S., Mann, G., Yang, J. (2014). Network-based biomarkers enhance classical approaches to prognostic gene expression signatures. International Conference on Bioinformatics 2014 (InCoB2014), Australia: BMC Public Health. <a href="http://dx.doi.org/10.1186/1752-0509-8-S4S5">[More Information]</a> Mactier, S., Kaufman (nee Alexander), K., Wang, P., Crossett, B., Pupo, G., Kohnke, P., Thompson, J., Scolyer, R., Yang, J., Mann, G., Christopherson, R. (2014). Protein signatures correspond to survival outcomes of AJCC stage III melanoma patients. Pigment Cell & Melanoma Research, 27(6), 1106-1116. <a href="http://dx.doi.org/10.1111/pcmr.12290">[ More Information]</a> Yang, P., Zhou, B., Yang, J., Zomaya, A. (2014). Stability of Feature Selection Algorithms and Ensemble Feature Selection Methods in Bioinformatics. In Mourad Elloumi, Albert Y. Zomaya (Eds.), Biological Knowledge Discovery Handbook: Preprocessing, Mining and Postprocessing of Biological Data, (pp. 333-352). New Jersey: John Wiley & Sons. Wygoda, J., Yang, J., Byrne, M., Wray, G. (2014). Transcriptomic analysis of the highly derived radial body plan of a sea urchin. Genome Biology and Evolution, 6(4), 964-973. <a href="http://dx.doi.org/10.1093/gbe/evu070">[M ore Information]</a> 2013 Oates, J., Casikar, I., Campain, A., Mueller, S., Yang, J., Reid, S., Condous, G. (2013). A prediction model for viability at the end of the first trimester after a single early pregnancy evaluation. Australian and New Zealand Journal of Obstetrics and Gynaecology, 53(1), 51-57. <a href="http://dx.doi.org/10.1111/ajo.12046">[Mo re Information]</a> Mann, G., Pupo, G., Campain, A., Carter, C., Schramm, S., Pianova, S., Gerega, S., Desilva, C., Lai, K., Wilmott, J., Hersey, P., Kefford, R., Thompson, J., Yang, J., Scolyer, R., et al (2013). BRAF Mutation, NRAS Mutation, and the Absence of an Immune-Related Expressed Gene Profile Predict Poor Outcome in Patients with Stage III Melanoma. Journal of Investigative Dermatology, 133(2), 509-517. <a href="http://dx.doi.org/10.1038/jid.2012.283">[ More Information]</a> Strbenac, D., Armstrong, N., Yang, J. (2013). Correction: Detection and classification of peaks in 5' cap RNA sequencing data. BMC Genetics, 14(1), Art. 767-1. <a href="http://dx.doi.org/10.1186/1471-2164-14-7 67">[More Information]</a> Strbenac, D., Armstrong, N., Yang, J. (2013). Detection and classification of peaks in 5’ cap RNA sequencing data. BMC Genomics, 14(Suppl 5), 1-11. <a href="http://dx.doi.org/10.1186/1471-2164-14-S 5-S9">[More Information]</a> Chung, S., Shen, W., Jayawardana, K., Wang, P., Yang, J., Shackel, N., Gillies, M. (2013). Differential gene expression profiling after conditional müller-cell ablation in a novel transgenic model. Investigative Ophthalmology and Visual Science, 54(3), 2142-2152. <a href="http://dx.doi.org/10.1167/iovs.12-1155">[ Publications for Jean Yang More Information]</a> Schramm, S., Li, S., Jayaswal, V., Fung, D., Campain, A., Pang, C., Scolyer, R., Yang, J., Mann, G., Wilkins, M. (2013). Disturbed protein-protein interaction networks in metastatic melanoma are associated with worse prognosis and increased functional mutation burden. Pigment Cell & Melanoma Research, 26(5), 708-722. <a href="http://dx.doi.org/10.1111/pcmr.12126">[ More Information]</a> Humphrey, S., Yang, G., Yang, P., Fazakerley, D., Stockli, J., Yang, J., James, D. (2013). Dynamic adipocyte phosphoproteome reveals that akt directly regulates mTORC2. Cell Metabolism, 17(6), 1009-1020. <a href="http://dx.doi.org/10.1016/j.cmet.2013.04.0 10">[More Information]</a> Patrick, E., Buckley, M., Yang, J. (2013). Estimation of data-specific constitutive exons with RNA-Seq data. BMC Bioinformatics, 14(31), 1-10. <a href="http://dx.doi.org/10.1186/1471-2105-14-3 1">[More Information]</a> Patrick, E., Buckley, M., Lin, D., Yang, J. (2013). Improved moderation for gene-wise variance estimation in RNA-Seq via the exploitation of external information. BMC Genomics, 14(Suppl 1), S1-S9. <a href="http://dx.doi.org/10.1186/1471-2164-14-S 1-S9">[More Information]</a> Wang, P., Yang, J., Raftery, M., Zhong, L., Wilson, S. (2013). Latin Square Dataset for Evaluating the Accuracy of Mass Spectrometry-based Protein Identification and Quantification. 2013 IEEE International Conference on Bioinformatics and Biomedicine (BIBM2013), Piscataway, United States: (IEEE) Institute of Electrical and Electronics Engineers. <a href="http://dx.doi.org/10.1109/BIBM.2013.673 2765">[More Information]</a> Schramm, S., Jayaswal, V., Goel, A., Li, S., Yang, J., Mann, G., Wilkins, M. (2013). Molecular interaction networks for the analysis of human disease: utility, limitations, and considerations. Proteomics, 13(23-24), 3393-3405. <a href="http://dx.doi.org/10.1002/pmic.201200570 ">[More Information]</a> Neff, C., Yang, J. (2013). Shark bites and public attitudes: Policy implications from the first before and after shark bite survey. Marine Policy, 38, 545-547. <a href="http://dx.doi.org/10.1016/j.marpol.2012.06 .017">[More Information]</a> Jayaswal, V., Schramm, S., Mann, G., Wilkins, M., Yang, J. (2013). VAN: an R package for identifying biologically perturbed networks via differential variability analysis. BMC Research Notes, 6(1), 1-9. <a href="http://dx.doi.org/10.1186/1756-0500-6-43 0">[More Information]</a> Yang, J., Markus, A., Mangs, A., Raitskin, O., Sperling, R., Morris, B. (2013). ZRANB2 localizes to supraspliceosomes and influences the alternative splicing of multiple genes in the transcriptome. Molecular Biology Reports, 40(9), 5381-5395. <a href="http://dx.doi.org/10.1007/s11033-013-263 7-9">[More Information]</a> 2012 Yang, P., Ma, J., Wang, P., Zhu, Y., Zhou, B., Yang, J. (2012). Improving X!Tandem on peptide identification from mass spectrometry by self-boosted percolator. IEEE - ACM Transactions on Computational Biology and Bioinformatics, 9(5), 1273-1280. <a href="http://dx.doi.org/10.1109/TCBB.2012.86" >[More Information]</a> Jayaswal, V., Lutherborrow, M., Yang, J. (2012). Measures of Association for Identifying MicroRNA-mRNA Pairs of Biological Interest. PloS One, 7(1), e29612-1-e29612-10. <a href="http://dx.doi.org/10.1371/journal.pone.002 9612">[More Information]</a> Bryant, A., Palma, C., Jayaswal, V., Yang, J., Lutherborrow, M., Ma, D. (2012). miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death. Molecular Cancer, 11(8), 1-9. <a href="http://dx.doi.org/10.1186/1476-4598-11-8" >[More Information]</a> Wang, P., Yang, P., Yang, J. (2012). OCAP: an open comprehensive analysis pipeline for iTRAQ. Bioinformatics, 28(10), 1404-1405. <a href="http://dx.doi.org/10.1093/bioinformatics/bt s150">[More Information]</a> Yang, P., Humphrey, S., Fazakerley, D., Prior, M., Yang, G., James, D., Yang, J. (2012). Re-Fraction: A machine learning approach for deterministic identification of protein homologues and splice variants in large-scale MS-based proteomics. Journal of Proteome Research, 11(5), 3035-3045. <a href="http://dx.doi.org/10.1021/pr300072j">[Mo re Information]</a> Schramm, S., Campain, A., Scolyer, R., Yang, J., Mann, G. (2012). Review and Cross-Validation of Gene Expression Signatures and Melanoma Prognosis. Journal of Investigative Dermatology, 132(2), 274-283. <a href="http://dx.doi.org/10.1038/jid.2011.305">[ Publications for Jean Yang More Information]</a> .00009.2011">[More Information]</a> 2011 Jayaswal, V., Lutherborrow, M., Ma, D., Yang, J. (2011). Identification of microRNA-mRNA modules using microarray data. BMC Genomics, 12(138), 1-32. <a href="http://dx.doi.org/10.1186/1471-2164-12-1 38">[More Information]</a> Loi, T., Campain, A., Bryant, A., Molloy, T., Lutherborrow, M., Turner, J., Yang, J., Ma, D. (2011). Discriminating lymphomas and reactive lymphadenopathy in lymph node biopsies by gene expression profiling. BMC Medical Genomics, 4(27), 1-10. <a href="http://dx.doi.org/10.1186/1755-8794-4-27" >[More Information]</a> Lutherborrow, M., Bryant, A., Jayaswal, V., Agapiou, D., PALMA, C., Yang, J., Ma, D. (2011). Expression Profiling of Cytogenetically Normal Acute Myeloid Leukemia Identifies MicroRNAs that Target Genes Involved in Monocytic Differentiation. American Journal Of Hematology, 86(1), 2-11. <a href="http://dx.doi.org/10.1002/ajh.21864">[Mo re Information]</a> Marques, F., Campain, A., Tomaszewski, M., Zukowska-Szczechowska, E., Yang, J., Charchar, F., Morris, B. (2011). Gene Expression Profiling Reveals Renin mRNA Overexpression in Human Hypertensive Kidneys and a Role for MicroRNAs. Hypertension, 58(6), 1093-1098. <a href="http://dx.doi.org/10.1161/HYPERTENSIO NAHA.111.180729">[More Information]</a> Yang, P., Ho, J., Yang, J., Zhou, B. (2011). Gene-gene interaction filtering with ensemble of filters. BMC Bioinformatics, 12(Supp 1: S10), 1-10. <a href="http://dx.doi.org/10.1186/1471-2105-12-S 1-S10">[More Information]</a> Marques, F., Campain, A., Davern, P., Yang, J., Head, G., Morris, B. (2011). Genes Influencing Circadian Differences in Blood Pressure in Hypertensive Mice. PloS One, 6(4), e19203-1-e19203-9. <a href="http://dx.doi.org/10.1371/journal.pone.001 9203">[More Information]</a> Wu, J., Dwyer, D., Dyer, W., Yang, J., Wang, B., Saksena, N. (2011). Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease. Retrovirology, 8(18), 1-21. <a href="http://dx.doi.org/10.1186/1742-4690-8-18" >[More Information]</a> Marques, F., Campain, A., Davern, P., Yang, J., Head, G., Morris, B. (2011). Global identification of the genes and pathways differentially expressed in hypothalamus in early and established neurogenic hypertension. Physiological Genomics, 43(12), 766-771. <a href="http://dx.doi.org/10.1152/physiolgenomics Collinson, E., Wimmer-Kleikamp, S., Gerega, S., Yang, J., Parish, C., Dawes, I., Stocker, R. (2011). The Yeast Homolog of Heme Oxygenase-1 Affords Cellular Antioxidant Protection via the Transcriptional Regulation of Known Antioxidant Genes. Journal of Biological Chemistry, 286(3), 2205-2214. <a href="http://dx.doi.org/10.1074/jbc.M110.18706 2">[More Information]</a> Peters, T., Bulger, D., Loi, T., Yang, J., Ma, D. (2011). Two-Step Cross-Entropy Feature Selection For Microarrays-Power Through Complementarity. IEEE - ACM Transactions on Computational Biology and Bioinformatics, 8(4), 1148-1151. <a href="http://dx.doi.org/10.1109/TCBB.2011.30" >[More Information]</a> 2010 Wang, P., Yang, P., Arthur, J., Yang, J. (2010). A dynamic wavelet-based algorithm for pre-processing tandem mass spectrometry data. Bioinformatics, 26(18), 2242-2249. <a href="http://dx.doi.org/10.1093/bioinformatics/bt q403">[More Information]</a> Yang, P., Yang, J., Zhou, B., Zomaya, A. (2010). A Review of Ensemble Methods in Bioinformatics. Current Bioinformatics, 5(4), 296-308. <a href="http://dx.doi.org/10.2174/1574893107940 72508">[More Information]</a> Jensen, S., Apisiridej, S., Kwong, S., Yang, J., Skurray, R., Firth, N. (2010). Analysis of the prototypical Staphylococcus aureus multiresistance plasmid pSK1. Plasmid, 64(3), 135-142. <a href="http://dx.doi.org/10.1016/j.plasmid.2010.0 6.001">[More Information]</a> Campain, A., Yang, J. (2010). Comparison study of microarray meta-analysis methods. BMC Bioinformatics, 11(408), 1-11. <a href="http://dx.doi.org/10.1186/1471-2105-11-4 08">[More Information]</a> Marques, F., Campain, A., Yang, J., Morris, B. (2010). Meta-Analysis of Genome-Wide Gene Expression Differences in Onset and Maintenance Phases of Genetic Hypertension. Hypertension, 56(2), 319-324. <a href="http://dx.doi.org/10.1161/HYPERTENSIO NAHA.110.155366">[More Information]</a> Publications for Jean Yang Karim, R., Gerega, S., Yang, J., Spillane, A., Carmalt, H., Scolyer, R., Lee, C. (2010). p16 and pRb immunohistochemical expression increases with increasing tumour grade in mammary phyllodes tumours. Histopathology, 56(7), 868-875. <a href="http://dx.doi.org/10.1111/j.1365-2559.201 0.03562.x">[More Information]</a> 2009 Jayaswal, V., Lutherborrow, M., Ma, D., Yang, J. (2009). Identification of microRNAs with regulatory potential using a matched microRNA -mRNA time-course data. Nucleic Acids Research, 37(8), e60-e60. <a href="http://dx.doi.org/10.1093/nar/gkp153">[M ore Information]</a> Karim, R., Gerega, S., Yang, J., Spillane, A., Carmalt, H., Scolyer, R., Lee, C. (2009). Phyllodes tumours of the breast: a clinicopathological analysis of 65 cases from a single institution. The Breast, 18(3), 165-170. <a href="http://dx.doi.org/10.1016/j.breast.2009.03. 001">[More Information]</a> Karim, R., Gerega, S., Yang, J., Horvath, L., Spillane, A., Carmalt, H., Scolyer, R., Lee, C. (2009). Proteins from the Wnt pathway are involved in the pathogenesis and progression of mammary phyllodes tumours. Journal of Clinical Pathology, 62(11), 1016-1020. <a href="http://dx.doi.org/10.1136/jcp.2009.066977 ">[More Information]</a> Karim, R., Li, W., Sanki, A., Colman, M., Yang, J., Thompson, J., Scolyer, R. (2009). Reduced p16 and increased cyclin D1 and pRb expression are correlated with progression in cutaneous melanocytic tumors. International Journal of Surgical Pathology, 17(5), 361-367. <a href="http://dx.doi.org/10.1177/1066896909336 177">[More Information]</a> 2008 Genomics, 9(SUPPL. 2, Article number 551), 1-15. <a href="http://dx.doi.org/10.1186/1471-2164-9-55 1">[More Information]</a> Wu, J., Dwyer, D., Dyer, W., Yang, J., Wang, B., Saksena, N. (2008). Transcriptional profiles in CD8+ T cells from HIV+ progressors on HAART are characterized by coordinated up-regulation of oxidative phosphorylation enzymes and interferon responses. Virology, 380(1), 124-135. <a href="http://dx.doi.org/10.1016/j.virol.2008.06.0 39">[More Information]</a> 2007 Xiao, Y., Segal, M., Yang, J., Yeh, R. (2007). A multi-array multi-SNP genotyping algorithm for Affymetrix SNP microarrays. Bioinformatics, 23(12), 1459-1467. Winn, V., Haimov-Kochman, R., Paquet, A., Yang, J., Madhusudhan, M., Gormley, M., Feng, K., Bernlohr, D., McDonagh, S., Pereira, L., et al (2007). Gene expression profiling of the human maternal-fetal interface reveals dramatic changes between midgestation and term. Endocrinology, 148(3), 1059-1079. Woodruff, P., Boushey, H., Dolganov, G., Barker, C., Yang, J., Donnelly, S., Ellwanger, A., Sidhu, S., Dao-Pick, T., Pantoja, C., et al (2007). Genome-wide profiling identifies elpithelial cell genes associated with asthma and with treatment response to corticosteroids. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 104(40), 15858-15863. Williams, E., Xiao, Y., Sickles, H., Shafer, P., Yona, G., Yang, J., Lin, D. (2007). Novel subdomains of the mouse olfactory bulb defined by molecular heterogeneity in the nascent external plexiform and glomerular layers. BMC Developmental Biology, 7(article no. 48), 1-15. Lewis, C., Yang, J., Huang, X., Banerjee, S., Balckburn, M., Baluk, P., McDonald, D., Blackwell, T., Nagabhushanam, V., Peters, W., et al (2008). Disease specific gene expression profiling in multiple models of lung disease. American Journal of Respiratory and Critical Care Medicine, 177(4), 376-387. <a href="http://dx.doi.org/10.1164/rccm.200702-33 3OC">[More Information]</a> 2005 Yang, J. (2008). Microarrays - Planning your experiment. In Ronald J.A. Trent (Eds.), Clinical Bioinformatics: Methods in Molecular Medicine, (pp. 71-85). New Jersey: Humana Press. Xiao, Y., Yang, J., Burckin, T., Shiue, L., Hartzog, G., Segal, M. (2005). Analysis of a Splice Array Experiment Elucidates Roles of Chromatin Elongation Factor Spt4-5 in Splicing. PLoS Computational Biology, 1(4), e39-0276-e39-0288. <a href="http://dx.doi.org/10.1371/journal.pcbi.001 0039">[More Information]</a> Kechris, K., Yang, J., Yeh, R. (2008). Prediction of alternatively skipped exons and splicing enhancers from exon junction arrays. BMC Woodruff, P., Koth, L., Yang, J., Rodriguez, M., Favoreto, S., Dolganov, G., Paquet, A., Erle, D. (2005). A distinctive alveolar macrophage activation state induced by cigarette smoking. American Journal of Respiratory and Critical Care Medicine, 172(11), 1383-1392. Publications for Jean Yang Kuperman, D., Lewis, C., Woodruff, P., Rodriguez, M., Yang, J., Dolganov, G., Fahy, J., Erle, D. (2005). Dissecting asthma using focused transgenic modeling and functional genomics. Journal of Allergy and Clinical Immunology, 116(2), 305-311. <a href="http://dx.doi.org/10.1016/j.jaci.2005.03.02 4">[More Information]</a> Gonzalez, R., Griffin, C., Yang, J., Allen, L., Tigue, Z., Dobbs, L. (2005). Freshly isolated rat alveolar type I cells, type II cells, and cultured type II cells have distinct molecular phenotypes. American Journal of Physiology: Lung Cellular and Molecular Physiology, 288(1), L179-L189. Yang, J., Xiao, Y., Segal, M. (2005). Identifying differentially expressed genes from microarray experiments via statistic synthesis. Bioinformatics, 21(7), 1084-1093. Barker, C., Griffin, C., Dolganov, G., Hanspers, K., Yang, J., Erle, D. (2005). Increased DNA microarray hybridization specificity using sscDNA targets. BMC Genomics, 6(57), 571-57- 8. Yang, J., Paquet, A. (2005). Preprocessing Two-Color Spotted Arrays. In R. Gentleman, V. Carey, S. Dudoit, R. Irizarry, W. Huber (Eds.), Bioinformatics and Computational Biology Solutions using R and Bioconductor, (pp. 49-70). New York: Springer. Xiao, Y., Segal, M., Yang, J. (2005). Stepwise Normalization of Two-Channel Spotted Microarrays. Statistical Applications in Genetics and Molecular Biology, 4(1), 4-1-4-29. 2004 Gentleman, R., Carey, V., Bates, D., Bolstad, B., Dettling, M., Dudoit, S., Ellis, B., Gautier, L., Ge, Y., Gentry, J., Yang, J., et al (2004). Bioconductor: open software development for computational biology and bioinformatics. Genome Biology, 5(10), R80.1-R80.16. Rodriguez, M., Paquet, A., Yang, J., Erle, D. (2004). Differential gene expression by integrin ß7+ and ß7-memory T helper cells. BMC Immunology, 5(13), 1-11. Lin, D., Yang, J., Scolnick, J., Brunet, L., Marsh, H., Peng, V., Okazaki, Y., Hayashizaki, Y., Speed, T., Ngai, J. (2004). Spatial patterns of gene expression in the olfactory bulb. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 101(34), 12718-12723. 2003 Diaz, E., Yang, J., Ferreira, T., Loh, K., Okazaki, Y., Hayashizaki, Y., Tessier-Lavigne, M., Speed, T., Ngai, J. (2003). Analysis of gene expression in the developing mouse retina. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 100(9), 5491-5496. Erle, D., Yang, J. (2003). Asthma investigators begin to reap the fruits of genomics. Genome Biology, 4(11), 232.1-232.3. Yang, J., Speed, T. (2003). Bioconductor R packages for exploratory analysis and normalization of cDNA microarray data. In G. Parmigiani, E. S. Garrett, R. A. Irizarry and S. L. Zeger (Eds.), The Analysis of Gene Expression Data: Methods and Software, (pp. 73-101). New York: Springer. Yang, J., Speed, T. (2003). Design and Analysis of Comparative Microarray Experiments. In T. P. Speed (Eds.), Statistical Analysis of Gene Expression Microarray Data, (pp. 35-92). 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Design issues for cDNA microarray experiments. Nature Reviews Genetics, 3(8), 579-588. Speed, T., Yang, J. (2002). Direct versus indirect designs for cDNA microarray experiments. Sankhya: The Indian Journal of Statistics, 64(Series A, Pt. 3), 707-721. Diaz, E., Ge, Y., Yang, J., Loh, K., Serafini, T., Okazaki, Y., Hayashizaki, Y., Speed, T., Ngai, J., Scheiffele, P. (2002). Molecular Analysis of Gene Expression in the Developing Pontocerebellar Projection System. Neuron, 36(3), 417-434. Publications for Jean Yang Yang, J., Dudoit, S., Luu, P., Lin, D., Peng, V., Ngai, J., Speed, T. (2002). Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Research, 30(4), e15. Dudoit, S., Yang, J., Callow, M., Speed, T. (2002). Statistical methods for identifying differentially expressed genes in replicated cDNA microarray experiments. Statistica Sinica, 12, 111-139. Dudoit, S., Yang, J., Bolstad, B. (2002). 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