Publications for Neil Hunter
Publications for Neil Hunter
2015
Nadkarni, M., Chhour, K., Browne, G., Byun, R.,
Nguyen, K., Chapple, C., Jacques, N., Hunter, N.
(2015). Age-dependant changes in
porphyromonas gingivalis and prevotella
species/phylotypes in healthy gingiva and
inflamed/diseased sub-gingival sites. Clinical
Oral Investigations, 19(4), 911-919. <a
href="http://dx.doi.org/10.1007/s00784-014-130
1-7">[More Information]</a>
Dingsdag, S., Yap, B., Hunter, N., Crossley, M.
(2015). Amino acid-linked
porphyrin-nitroimidazole antibiotics targeting
Porphyromonas gingivalis. Organic and
Biomolecular Chemistry, 13(1), 98-109. <a
href="http://dx.doi.org/10.1039/c4ob01841a">[
More Information]</a>
2014
Kianoush, N., Adler, C., Nguyen, K., Browne,
G., Simonian, M., Hunter, N. (2014). Bacterial
Profile of Dentine Caries and the Impact of pH
on Bacterial Population Diversity. PloS One,
9(3), 1-10. <a
href="http://dx.doi.org/10.1371/journal.pone.009
2940">[More Information]</a>
Guo, W., Ye, P., Yu, H., Liu, Z., Yang, P.,
Hunter, N. (2014). CD24 activates the NLRP3
inflammasome through c-Src kinase activity in a
model of the lining epithelium of inflamed
periodontal tissues. Immunity, Inflammation and
Disease, 2(4), 239-253.
Nadkarni, M., Chen, Z., Wilkins, M., Hunter, N.
(2014). Comparative Genome Analysis of
Lactobacillus rhamnosus Clinical Isolates from
Initial Stages of Dental Pulp Infection:
Identification of a New Exopolysaccharide
Cluster. PloS One, 9(3), 1-14. <a
href="http://dx.doi.org/10.1371/journal.pone.009
0643">[More Information]</a>
Ye, P., Yu, H., Simonian, M., Hunter, N. (2014).
Expression patterns of tight junction components
induced by CD24 in an oral epithelial
cell-culture model correlated to affected
periodontal tissues. Journal of Periodontal
Research, 49(2), 253-259. <a
href="http://dx.doi.org/10.1111/jre.12102">[Mor
e Information]</a>
Houshmandi, M., Ye, P., Hunter, N. (2014).
Glial Network Responses to Polymicrobial
Invasion of Dentin. Caries Research, 48,
534-548.
Kianoush, N., Nguyen, K., Browne, G.,
Simonian, M., Hunter, N. (2014). pH gradient
and distribution of streptococci, lactobacilli,
prevotellae, and fusobacteria in carious dentine.
Clinical Oral Investigations, 18(2), 659-669. <a
href="http://dx.doi.org/10.1007/s00784-013-100
9-0">[More Information]</a>
Nadkarni, M., Chhour, K., Chapple, C., Nguyen,
K., Hunter, N. (2014). The profile of
Porphyromonas gingivalis kgp biotype and
firmA genotype mosaic in subgingival plaque
samples. FEMS Microbiology Letters, 361(2),
190-194. <a
href="http://dx.doi.org/10.1111/1574-6968.1263
1">[More Information]</a>
2013
Ye, P., Harty, D., Commandeur, Z., Hunter, N.
(2013). Binding of Streptococcus gordonii to oral
epithelial monolayers increases paracellular
barrier function. Microbial Pathogenesis, 56,
53-59. <a
href="http://dx.doi.org/10.1016/j.micpath.2012.1
1.004">[More Information]</a>
Chen, Z., Wilkins, M., Hunter, N., Nadkarni, M.
(2013). Draft genome sequences of two clinical
isolates of Lactobacillus rhamnosus initial stages
of dental pulp infection. Genome
Announcements, 1(1), e00073-12. <a
href="http://dx.doi.org/10.1128/genomeA.00073
-12">[More Information]</a>
Zhou, X., Gao, J., Hunter, N., Potempa, J.,
Nguyen, K. (2013). Sequence-independent
processing site of the C-terminal domain (CTD)
influences maturation of the RgpB protease from
Porphyromonas gingivalis. Molecular
Microbiology, 89(5), 903-917. <a
href="http://dx.doi.org/10.1111/mmi.12319">[M
ore Information]</a>
Charadram, N., Austin, C., Trimby, P.,
Simonian, M., Swain, M., Hunter, N. (2013).
Structural analysis of reactionary dentin formed
in response to polymicrobial invasion. Journal of
Structural Biology, 181(3), 207-222. <a
href="http://dx.doi.org/10.1016/j.jsb.2012.12.005
">[More Information]</a>
2012
Martin, E., Hunter, N., Jacques, N., Nadkarni, M.
(2012). A Method of Detecting Microorganisms
(Japan). Patent No. 1311706, 2001276180,
516360, 7244480. Austria, Belgium, Cyprus,
Denmark, Finland, France, Germany, Greece,
Ireland, Italy, Luxembourg, Monaco,
Netherlands, Portugal, Spain, Sweden,
Switzerland, Turkey, United Kingdom.
Hunter, N., Collyer, C., De Carlo, A. (2012). A
Method Of Prophylaxis And Treatment And
Agents Useful For Same (Canada). Patent No.
2375269, 515853, 7319086, 781704. Canada,
New Zealand.
Mostofi Zadeh Farahani, R., Sarrafpour, B.,
Publications for Neil Hunter
Simonian, M., Li, Q., Hunter, N. (2012).
Directed glia-assisted angiogenesis in a mature
neurosensory structure: Pericytes mediate an
adaptive response in human dental pulp that
maintains blood-barrier function. The Journal of
Comparative Neurology, 520(17), 3803-3826. <a
href="http://dx.doi.org/10.1002/cne.23162">[Mo
re Information]</a>
Nadkarni, M., Browne, G., Chhour, K., Byun, R.,
Nguyen, K., Chapple, C., Jacques, N., Hunter, N.
(2012). Pattern of distribution of Prevotella
species/phylotypes associated with healthy
gingiva and periodontal disease. European
Journal of Clinical Microbiology and Infectious
Diseases, 31(11), 2989-2999. <a
href="http://dx.doi.org/10.1007/s10096-012-165
1-5">[More Information]</a>
Charadram, N., Mostofi Zadeh Farahani, R.,
Harty, D., Rathsam, C., Swain, M., Hunter, N.
(2012). Regulation of reactionary dentin
formation by odontoblasts in response to
polymicrobial invasion of dentin matrix. Bone,
50(1), 265-275. <a
href="http://dx.doi.org/10.1016/j.bone.2011.10.0
31">[More Information]</a>
Harty, D., Mostofi Zadeh Farahani, R.,
Simonian, M., Hunter, L., Hunter, N. (2012).
Streptococcus gordonii FSS2 Challisin affects
fibrin clot formation by digestion of the aC
region and cleavage of the N-terminal region of
the BB chains of fibrinogen. Thrombosis and
Haemostasis, 108(2), 236-246. <a
href="http://dx.doi.org/10.1160/TH12-01-0032"
>[More Information]</a>
Yun, P., Li, N., Collyer, C., Hunter, N. (2012).
The K1K2 Region of Lys-Gingipain of
Porphyromonas gingivalis Blocks Induction of
HLA Expression by Gamma Interferon. Infection
and Immunity, 80(10), 3733-3741. <a
href="http://dx.doi.org/10.1128/IAI.00528-12">[
More Information]</a>
Gao, J., Lu, Y., Browne, G., Yap, B., Trewhella,
J., Hunter, N., Nguyen, K. (2012). The role of
heme-binding by DNA-protective protein from
starved-cells (Dps) in the tolerance of
Porphyromonas gingivalis to heme toxicity.
Journal of Biological Chemistry, 287(50),
42243-42258. <a
href="http://dx.doi.org/10.1074/jbc.M112.39278
7">[More Information]</a>
2011
Zou, W., Hunter, N., Swain, M. (2011).
Application of Polychromatic muCT for Mineral
Density Determination. Journal of Dental
Research, 90(1), 18-30. <a
href="http://dx.doi.org/10.1177/0022034510378
429">[More Information]</a>
Mostofi Zadeh Farahani, R., Simonian, M.,
Hunter, N. (2011). Blueprint of an Ancestral
Neurosensory Organ
Revealed in Glial Networks in Human Dental
Pulp. The Journal of Comparative Neurology,
519(16), 3306-3326. <a
href="http://dx.doi.org/10.1002/cne.22701">[Mo
re Information]</a>
Harty, D., Hunter, N. (2011). Carboxypeptidase
activity common to viridans group steptococci
cleaves angiotensin I to angiotensin II: an
activity homologous to angiotensin-converting
enzyme (ACE). Microbiology, 157(7),
2143-2151. <a
href="http://dx.doi.org/10.1099/mic.0.048710-0"
>[More Information]</a>
Ye, P., Yu, H., Simonian, M., Hunter, N. (2011).
Ligation of CD24 expressed by oral eipithelial
cells induced kinase dependent decrease in
paracellular permeability mediated by tight
junction proteins. Biochemical and Biophysical
Research Communications, 412(1), 165-169. <a
href="http://dx.doi.org/10.1016/j.bbrc.2011.07.0
67">[More Information]</a>
Li, N., Yun, P., Jeffries, C., Langley, D.,
Gamsjaeger, R., Church, W., Hunter, N., Collyer,
C. (2011). The modular structure of
haemagglutinin/adhesin regions in gingipains of
Porphyromonas gingivalis. Molecular
Microbiology, 81(5), 1358-1373. <a
href="http://dx.doi.org/10.1111/j.1365-2958.201
1.07768.x">[More Information]</a>
2010
Mostofi Zadeh Farahani, R., Nguyen, K.,
Simonian, M., Hunter, N. (2010). Adaptive
calcified matrix response of dental pulp to
bacterial invasion in associated with
establishment of a network of Glial Fibrillary
Acidic Protein+/Glutamine Synthetase+ Cells.
The American Journal of Pathology, 177(4),
1901-1914. <a
href="http://dx.doi.org/10.2353/ajpath.2010.1000
73">[More Information]</a>
Gao, J., Nguyen, K., Hunter, N. (2010).
Characterization of a hemophore-like protein
from Porphyromonas gingivalis. Journal of
Biological Chemistry, 285(51), 40028-40038. <a
href="http://dx.doi.org/10.1074/jbc.M110.16353
5">[More Information]</a>
Nadkarni, M., Simonian, M., Harty, D., Zoellner,
H., Jacques, N., Hunter, N. (2010). Lactobacilli
Are Prominent in the Initial Stages of
Polymicrobial Infection of Dental Pulp. Journal
of Clinical Microbiology, 48(5), 1732-1740. <a
href="http://dx.doi.org/10.1128/JCM.01912-09"
>[More Information]</a>
Hunter, N., Collyer, C., De Carlo, A. (2010).
Publications for Neil Hunter
Prophylaxis And Treatment Of P. Gingivalis
Infection. Patent No. 1189630, 60043936.4-08.
Germany.
Li, N., Yun, P., Nadkarni, M., Nazila, B.,
Nguyen, K., Lee, M., Hunter, N., Collyer, C.
(2010). Structure determination and analysis of a
haemolytic gingipain adhesin domain from
Porphyromonas gingivalis. Molecular
Microbiology, 76(4), 861-873. <a
href="http://dx.doi.org/10.1111/j.1365-2958.201
0.07123.x">[More Information]</a>
2009
Gao, J., Nguyen, K., Hunter, N. (2009). A novel
haem uptake in Porphyromonas gingivalis.
Journal of Dental Research.
Nadkarni, M., Martin, E., Jacques, N., Hunter, N.
(2009). Caries. Encyclopedia of Molecular
Mechanisms of Disease. (Vol. 1, pp. 279-280).
Berlin: Springer.
Ye, P., Nadkarni, M., Simonian, M., Hunter, N.
(2009). CD24 regulated gene expression and
distribution of tight junction proteins is
associated with altered barrier function in oral
epithelial monolayers. BMC Cell Biology, 10,
1-16. <a
href="http://dx.doi.org/10.1186/1471-2121-10-2"
>[More Information]</a>
Zou, W., Gao, J., Jones, A., Hunter, N., Swain,
M. (2009). Characterization of a novel
calibration method for mineral density
determination of dentine by x-ray
micro-tomography. The Analyst, 134(1), 72-79.
<a
href="http://dx.doi.org/10.1039/b806884d">[Mo
re Information]</a>
Nadkarni, M., Chhour, K., Browne, G., Jacques,
N., Hunter, N. (2009). Lysine gingipain (kgp)
biovars of Porphyromonas gingivalis exhibit
differential distribution on oral mucosal sites.
Journal of Clinical Microbiology, 47(10),
3350-3352. <a
href="http://dx.doi.org/10.1128/JCM.00753-09"
>[More Information]</a>
Nadkarni, M., Martin, E., Hunter, N., Jacques, N.
(2009). Methods for optimizing DNA extraction
before quantifying oral bacterial numbers by
real-time PCR. FEMS Microbiology Letters, 296,
45-51. <a
href="http://dx.doi.org/10.1111/j.1574-6968.200
9.01629.x">[More Information]</a>
Yap, B., Simpkins, G., Collyer, C., Hunter, N.,
Crossley, M. (2009). Porphyrin-linked
nitroimidazole antibiotics targeting:
Prophyromonas gingivalis. Organic and
Biomolecular Chemistry, 7(14), 2855-2863. <a
href="http://dx.doi.org/10.1039/b904340c">[Mo
re Information]</a>
Nguyen, K., Zylicz, J., Szczesny, P., Sroka, A.,
Hunter, N., Potempa, J. (2009). Verification of a
topology model of PorT as an integral
outer-membrane protein in Porphyromonas
gingivalis. Microbiology, 155(2), 328-337. <a
href="http://dx.doi.org/10.1099/mic.0.024323-0"
>[More Information]</a>
2008
Gao, J., Xie, H., Nguyen, K., Hunter, N. (2008).
Detection and characterization of novel outer
membrane proteins involved in heme binding by
Porphyromonas gingivalis. Journal of
Biotechnology, 136, S88. <a
href="http://dx.doi.org/10.1016/j.jbiotec.2008.07
.199">[More Information]</a>
Smith-Vaughan, H., Byun, R., Halpin, S.,
Nadkarni, M., Jacques, N., Hunter, N., Morris,
P., Leach, A. (2008). Interventions for
prevention of otitis media may be most effective
if implemented in the first weeks of life.
International Journal of Pediatric
Otorhinolaryngology, 72, 57-61. <a
href="http://dx.doi.org/10.1016/j.ijporl.2007.09.0
12">[More Information]</a>
Langley, D., Harty, D., Jacques, N., Hunter, N.,
Guss, M., Collyer, C. (2008). Structure of
N-acetyl-B-D-glucosaminidase (GcnA) from the
Endocarditis Pathogen Streptococcus gordonii
and its Complex with the Mechanism-based
Inhibitor NAG-thiazoline. Journal of Molecular
Biology, 377, 104-116. <a
href="http://dx.doi.org/10.1016/j.jmb.2007.09.02
8">[More Information]</a>
2007
Yun, P., DeCarlo, A., Hunter, N. (2007).
Blockade of protese-activated receptors on T
cells corelated with altered proteloysis of CD27
by gingipains of porphyromonas gingivalis.
Clinical and Experimental Immunology, 150(2),
217-229. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17937677">[More Information]</a>
Fong, M., Darendeliler, M., Hunter, N., Shen, G.
(2007). Epithelial cells in PDL are critical in
resuming the integral relation between tooth root
and supporting bone after trauma - A
transplantation experiment. Archives of Oral
Biology, 52(2), 182-188. <a
href="http://dx.doi.org/10.1016/j.archoralbio.200
6.08.017">[More Information]</a>
Byun, R., Carlier, J., Jacques, N., Marchandin,
H., Hunter, N. (2007). Veillonella denticariosi
sp. nov., isolated from human carious dentine.
International Journal of Systematic and
Evolutionary Microbiology, 57(12), 2844-2848.
<a
Publications for Neil Hunter
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=18048736">[More Information]</a>
2006
Yun, P., DeCarlo, A., Hunter, N. (2006).
Gingipains of porphyromonas gingivalis
modulate leukocyte adhesion molecule
expression induced in human endothelial cells by
ligation of CD99. Infection and Immunity, 74(3),
1661-1672. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16495537">[More Information]</a>
Smith-Vaughan, H., Byun, R., Nadkarni, M.,
Jacques, N., Hunter, N., Halpin, S., Morris, P.,
Leach, A. (2006). Measuring nasal bacterial load
and its association with otitis media. B M C Ear
Nose and Throat Disorders, 6(1), 10. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16686940">[More Information]</a>
Ye, P., Nadkarni, M., Hunter, N. (2006).
Regulation of E-cadherin and TGF-β3 expression
by CD24 in cultured oral epithelial cells.
Biochemical and Biophysical Research
Communications, 349(1), 229-235. <a
href="http://dx.doi.org/10.1016/j.bbrc.2006.08.0
33">[More Information]</a>
2005
Yun, P., DeCarlo, A., Chapple, C., Collyer, C.,
Hunter, N. (2005). Binding of Porphyromonas
gingivalis gingipains to human CD4(+) T cells
preferentially down-regulates surface CD2 and
CD4 with little affect on co-stimulatory molecule
expression. Microbial Pathogenesis, 38(2-3),
85-96. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15748810">[More Information]</a>
Yun, P., DeCarlo, A., Chapple, C., Hunter, N.
(2005). Functional implication of the hydrolysis
of platelet endothelial cell adhesion molecule 1
(CD31) by gingipains of porphyromonas
gingivalis for the pathology periodontal disease.
Infection and Immunity, 73(3), 1386-1398. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15731036">[More Information]</a>
Ye, P., Simonian, M., Nadkarni, M., DeCarlo,
A., Chapple, C., Hunter, N. (2005). Identification
of epithelial auto-antigens associated
with periodontal disease. Clinical and
Experimental Immunology, 139(2), 328-337. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15654832">[More Information]</a>
Chhour, K., Nadkarni, M., Byun, R., Martin, E.,
Jacques, N., Hunter, N. (2005). Molecular
Analysis of Microbial Diversity in Advanced
Caries. Journal of Clinical Microbiology, 43(2),
843-849. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15695690">[More Information]</a>
2004
Nadkarni, M., Caldon, E., Chhour, K., Fisher, I.,
Martin, E., Jacques, N., Hunter, N. (2004).
Carious Dentine Provides a Habitat for a
Complex Array of Novel Prevotella-Like
Organisms. Journal of Clinical Microbiology,
42(11), 5238-5244.
Harty, D., Chen, Y., Simpson, C., Berg, T.,
Cook, S., Mayo, J., Hunter, N., Jacques, N.
(2004). Characterisation Of A Novel
Homodimeric N-Acetyl-B-D-Glucosaminidase
From Streptococcus Gordonii. Biochemical and
Biophysical Research Communications, 319(2),
439-447. <a
href="http://dx.doi.org/10.1016/j.bbrc.2004.05.0
15">[More Information]</a>
Langley, D., Harty, D., Graham, S., Guss, M.,
Hunter, N., Collyer, C. (2004). Crystallization Of
Gcna, An N-Acetyl-β-D-Glucosaminidase, From
Streptococcus Gordonii. Acta Crystallographica.
Section D: Biological Crystallography, D60,
1910-1911.
Nadkarni, M., Nguyen, K., Chapple, C.,
DeCarlo, A., Jacques, N., Hunter, N. (2004).
Distribution Of Porphyromonas Gingivalis
Biotypes Defined By Alleles Of The Kgp
(Lys-Gingipain) Gene. Journal of Clinical
Microbiology, 42(8), 3873-3876.
Nguyen, K., DeCarlo, A., Paramaesvaran, M.,
Collyer, C., Langley, D., Hunter, N. (2004).
Humoral Responses To Porphyromonas
gingivalis Gingipain Adhesin Domains In
Subjects With Chronic Periodontitis. Infection
and Immunity, 72(3), 1374-1382.
Byun, R., Nadkarni, M., Chhour, K., Martin, E.,
Jacques, N., Hunter, N. (2004). Quantitative
Analysis Of Diverse Lactobacillus Species
Present In Advanced Dental Caries. Journal of
Clinical Microbiology, 42(7), 3128-3136.
DeCarlo, A., Nadkarni, M., Paramaesvaran, M.,
Yun, P., Collyer, C., Hunter, N. (2004). Serum
Antibodies Against The Hemoglobin-Binding
Domain (HA2) Of Porphyromonas Gingivalis.
Journal of Periodontal Research, 39(4),
228-235.
2003
Ye, P., Simonian, M., Chapple, C., Gibbins, J.,
Kumar, R., Hunter, N. (2003). Differential
Publications for Neil Hunter
expression of transforming growth factors-beta1,
-beta2, -beta3 and the type I, II, II receptors in
the linng epithelia of inflamed gingiva.
Pathology, 35(5), 384-392.
Paramaesvaran, M., Nguyen, K., Caldon, E.,
McDonald, J., Najdi, S., Gonzaga, G., Langley,
D., DeCarlo, A., Hunter, N., Crossley, M.,
Collyer, C. (2003). Porphyrin-mediated cell
surface heme capture from hemoglobin by
Porphyromanas gingivalis. Journal of
Bacteriology, 185(8), 2528-2537.
Ye, P., Harty, D., Chapple, C., Nadkarni, M.,
DeCarlo, A., Hunter, N. (2003). Streptococci and
Actinomyces induce antibodies which cross react
with epithelial antigens in periodontitis. Clinical
and Experimental Immunology, 131(3), 468-476.
2002
Nadkarni, M., Martin, E., Jacques, N., Hunter, N.
(2002). Determination of bacterial load by
real-time PCR using a broad-range (universal)
probe and primers set. Microbiology, 148(1),
257-266.
Zoellner, H., Chapple, C., Hunter, N. (2002).
Microvasculature in gingivitis and chronic
periodontitis: disruption of vascular networks
with protracted inflammation. Microscopy
Research and Technique, 56(1), 15-31. <a
href="http://dx.doi.org/10.1002/jemt.10009">[M
ore Information]</a>
Yun, P., DeCarlo, A., Collyer, C., Hunter, N.
(2002). Modulation of an interleukin-12 and
interferon gamma synergistic feedback
regulatory cycle of T-cell/monocyte co-cultures
by Porphyromonas gingivalis lipopolysaccharide
in the absence or presence of cysteine
proteinases. Infection and Immunity, 70(10),
5695-5705.
Martin, E., Nadkarni, M., Jacques, N., Hunter, N.
(2002). Quantitative microbiological study of
human carious dentine by culture and real-time
PCR: association of anaerobes with
histopathological changes in chronic pulpitis.
Journal of Clinical Microbiology, 40(5),
1698-1704.
Hunter, N., Nguyen, K., McDonald, J., Quinn,
M., Langley, D., Crossley, M., Collyer, C.
(2002). Structural requirements for recognition
of essential porphyrin by Porphyromonas
gingivalis. Journal of Porphyrins and
Phthalocyanines, 6(12), 774-782.