Publications for Ky-Anh Nguyen Publications for Ky-Anh Nguyen 2016 de Diego, I., Ksiazek, M., Mizgalska, D., Koneru, L., Golik, P., Szmigielski, B., Nowak, M., Nowakowska, Z., Potempa, B., Gao, J., Kwan, A., Trewhella, J., Nguyen, K., et al (2016). The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domain. Scientific Reports, 6, 1-17. <a href="http://dx.doi.org/10.1038/srep23123">[Mo re Information]</a> 2015 Ramos-Junior, E., Morandini, A., Almeida da Silva, C., Franco, E., Potempa, J., Nguyen, K., Oliveira, A., Zamboni, D., Ojcius, D., Scharfstein, J., et al (2015). A Dual Role for P2X7 Receptor during Porphyromonas gingivalis Infection. Journal of Dental Research, 94(9), 1233-1242. <a href="http://dx.doi.org/10.1177/0022034515593 465">[More Information]</a> Nadkarni, M., Chhour, K., Browne, G., Byun, R., Nguyen, K., Chapple, C., Jacques, N., Hunter, N. (2015). Age-dependant changes in porphyromonas gingivalis and prevotella species/phylotypes in healthy gingiva and inflamed/diseased sub-gingival sites. Clinical Oral Investigations, 19(4), 911-919. <a href="http://dx.doi.org/10.1007/s00784-014-130 1-7">[More Information]</a> Veillard, F., Potempa, B., Guo, Y., Ksiazek, M., Sztukowska, M., Houston, J., Koneru, L., Nguyen, K., Potempaa, J. (2015). Purification and characterisation of recombinant His-tagged RgpB gingipain from Porphymonas gingivalis. Biological Chemistry, 396(4), 377-384. <a href="http://dx.doi.org/10.1515/hsz-2014-0304" >[More Information]</a> 2014 Kianoush, N., Adler, C., Nguyen, K., Browne, G., Simonian, M., Hunter, N. (2014). Bacterial Profile of Dentine Caries and the Impact of pH on Bacterial Population Diversity. PloS One, 9(3), 1-10. <a href="http://dx.doi.org/10.1371/journal.pone.009 2940">[More Information]</a> Siddiqui, H., Yoder-Himes, D., Mizgalska, D., Nguyen, K., Potempa, J., Olsen, I. (2014). Genome Sequence of Porphyromonas gingivalis Strain HG66 (DSM 28984). Genome Announcements, 2(5), 1-2. <a href="http://dx.doi.org/10.1128/genomeA.00947 -14">[More Information]</a> Kianoush, N., Nguyen, K., Browne, G., Simonian, M., Hunter, N. (2014). pH gradient and distribution of streptococci, lactobacilli, prevotellae, and fusobacteria in carious dentine. Clinical Oral Investigations, 18(2), 659-669. <a href="http://dx.doi.org/10.1007/s00784-013-100 9-0">[More Information]</a> Morandini, A., Ramos-Junior, E., Potempa, J., Nguyen, K., Oliveira, A., Bellio, M., Ojcius, D., Scharfstein, J., Coutinho-Silva, R. (2014). Porphyromonas gingivalis Fimbriae Dampen P2X7-Dependent Interleukin-1B Secretion. Journal of Innate Immunity, 6(6), 831-845. <a href="http://dx.doi.org/10.1159/000363338">[M ore Information]</a> Nadkarni, M., Chhour, K., Chapple, C., Nguyen, K., Hunter, N. (2014). The profile of Porphyromonas gingivalis kgp biotype and firmA genotype mosaic in subgingival plaque samples. FEMS Microbiology Letters, 361(2), 190-194. <a href="http://dx.doi.org/10.1111/1574-6968.1263 1">[More Information]</a> 2013 Nguyen, K., Potempa, J. (2013). Gingipain R. In Neil D. Rawlings, Guy Salvesen (Eds.), Handbook of Proteolytic Enzymes: Volume 3, (pp. 2328-2336). London, United Kingdom: Elsevier. Pyrc, K., Milewska, A., Kantyka, T., Sroka, A., Maresz, K., Koziel, J., Nguyen, K., Enghild, J., Knudsen, A., Potempaa, J. (2013). Inactivation of Epidermal Growth Factor by Porphyromonas gingivalis as a Potential Mechanism for Periodontal Tissue Damage. Infection and Immunity, 81(1), 55-64. <a href="http://dx.doi.org/10.1128/IAI.00830-12">[ More Information]</a> Veillard, F., Sztukowska, M., Mizgalska, D., Ksiazek, M., Houston, J., Potempa, B., Enghild, J., Thogersen, I., Gomis-Ruth, F., Nguyen, K., et al (2013). Inhibition of gingipains by their profragments as the mechanism protecting porphyromonas gingivalis against premature activation of secreted proteases. Biochimica et Biophysica Acta. General Subjects, 1830 (8), 4218-4228. <a href="http://dx.doi.org/10.1016/j.bbagen.2013.04 .005">[More Information]</a> Maresz, K., Hellvard, A., Sroka, A., Adamowicz, K., Bielecka, E., Koziel, J., Gawron, K., Mizgalska, D., Marcinska, K., Benedyk, M., Nguyen, K., et al (2013). Porphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD). PLoS Pathogens, 9(9), 1-10. <a href="http://dx.doi.org/10.1371/journal.ppat.100 3627">[More Information]</a> Publications for Ky-Anh Nguyen Zhou, X., Gao, J., Hunter, N., Potempa, J., Nguyen, K. (2013). Sequence-independent processing site of the C-terminal domain (CTD) influences maturation of the RgpB protease from Porphyromonas gingivalis. Molecular Microbiology, 89(5), 903-917. <a href="http://dx.doi.org/10.1111/mmi.12319">[M ore Information]</a> 2012 Sztukowska, M., Veillard, F., Potempa, B., Bogyo, M., Enghild, J., Thogersen, I., Nguyen, K., Potempa, J. (2012). Disruption of gingipain oligomerization into non-covalent cell-surface attached complexes. Biological Chemistry, 393(9), 971-977. <a href="http://dx.doi.org/10.1515/hsz-2012-0175" >[More Information]</a> Nadkarni, M., Browne, G., Chhour, K., Byun, R., Nguyen, K., Chapple, C., Jacques, N., Hunter, N. (2012). Pattern of distribution of Prevotella species/phylotypes associated with healthy gingiva and periodontal disease. European Journal of Clinical Microbiology and Infectious Diseases, 31(11), 2989-2999. <a href="http://dx.doi.org/10.1007/s10096-012-165 1-5">[More Information]</a> Gao, J., Lu, Y., Browne, G., Yap, B., Trewhella, J., Hunter, N., Nguyen, K. (2012). The role of heme-binding by DNA-protective protein from starved-cells (Dps) in the tolerance of Porphyromonas gingivalis to heme toxicity. Journal of Biological Chemistry, 287(50), 42243-42258. <a href="http://dx.doi.org/10.1074/jbc.M112.39278 7">[More Information]</a> 2011 Rapala-Kozik, M., Bras, G., Karkowska-Kuleta, J., Sroka, A., Herwald, H., Nguyen, K., Eick, S., Potempa, J., Kozik, A. (2011). Adsorption of Components of the Plasma Kinin-forming System on the Surface of Porphyromonas gingivalis Involves Gingipains as the Major Docking Platforms. Infection and Immunity, 79(2), 797-805. <a href="http://dx.doi.org/10.1128/IAI.00966-10">[ More Information]</a> Cerda-Costa, N., Guevara, T., Karim, A., Ksiazek, M., Nguyen, K., Arolas, J., Potempa, J., Gomis-Ruth, F. (2011). The structure of the catalytic domain of Tannerella forsythia karilysin reveals it is a bacterial xenologue of animal matrix metalloproteinases. Molecular Microbiology, 79(1), 119-132. <a href="http://dx.doi.org/10.1111/j.1365-2958.201 0.07434.x">[More Information]</a> 2010 Karim, A., Kulczycka, M., Kantyka, T., Dubin, G., Jabaiah, A., Daugherty, P., Thogerson, I., Enghild, J., Nguyen, K., Potempa, J. (2010). A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037. Biological Chemistry, 391(1), 105-117. <a href="http://dx.doi.org/10.1515/BC.2010.009">[ More Information]</a> Mostofi Zadeh Farahani, R., Nguyen, K., Simonian, M., Hunter, N. (2010). Adaptive calcified matrix response of dental pulp to bacterial invasion in associated with establishment of a network of Glial Fibrillary Acidic Protein+/Glutamine Synthetase+ Cells. The American Journal of Pathology, 177(4), 1901-1914. <a href="http://dx.doi.org/10.2353/ajpath.2010.1000 73">[More Information]</a> Gao, J., Nguyen, K., Hunter, N. (2010). Characterization of a hemophore-like protein from Porphyromonas gingivalis. Journal of Biological Chemistry, 285(51), 40028-40038. <a href="http://dx.doi.org/10.1074/jbc.M110.16353 5">[More Information]</a> Guo, Y., Nguyen, K., Potempa, J. (2010). Dichotomy of gingipains action as virulance factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins. Periodontology 2000, 54, 15-44. <a href="http://dx.doi.org/10.1111/j.1600-0757.201 0.00377.x">[More Information]</a> Wegner, N., Wait, R., Sroka, A., Eick, S., Nguyen, K., Lundberg, K., Kinloch, A., Culshaw, S., Potempa, J., Venables, P. (2010). Peptidylarginine Deiminase From Porphyromonas gingivalis Citrullinates Human Fibrinogen and alpha-Enolase. Arthritis & Rheumatology, 62(9), 2662-2672. <a href="http://dx.doi.org/10.1002/art.27552">[Mor e Information]</a> Koziel, J., Karim, A., Przbyszewska, K., Ksiazek, M., Rapala-Kozik, M., Nguyen, K., Potempa, J. (2010). Proteolytic inactivation of LL-37 by Karilysin, a Novel Virulence Mechanism of Tannerella forsythia. Journal of Innate Immunity, 2(3), 288-293. <a href="http://dx.doi.org/10.1159/000281881">[M ore Information]</a> Li, N., Yun, P., Nadkarni, M., Nazila, B., Nguyen, K., Lee, M., Hunter, N., Collyer, C. (2010). Structure determination and analysis of a haemolytic gingipain adhesin domain from Porphyromonas gingivalis. Molecular Microbiology, 76(4), 861-873. <a href="http://dx.doi.org/10.1111/j.1365-2958.201 0.07123.x">[More Information]</a> Publications for Ky-Anh Nguyen 2009 Gao, J., Nguyen, K., Hunter, N. (2009). A novel haem uptake in Porphyromonas gingivalis. Journal of Dental Research. Potempa, M., Potempa, J., Kantyka, T., Nguyen, K., Wawrzonek, K., Manandhar, S., Popadiak, K., Riesbeck, K., Eick, S., Blom, A. (2009). Interpain A, a Cysteine Proteinase from Prevotella intermedia, Inhibits Complement by Degrading Complement Factor C3. P L o S Pathogens, 5(2), e1000316-1-e1000316-14. <a href="http://dx.doi.org/10.1371/journal.ppat.100 0316">[More Information]</a> Monteiro, A., Scovino, A., Raposo, S., Gaze, V., Cruz, C., Svensjo, E., Narciso, M., Colombo, A., Pesquero, J., Feres-Filho, E., Nguyen, K. (2009). Kinin Danger Signals Proteolytically Released by Gingipain Induce Fimbriae-Specific IFN-and IL-17-Producing T Cells in Mice Infected Intramucosally with Porphyromonas Gingivalis. The Journal of Immunology, 183(183), 3700-3711. <a href="http://dx.doi.org/10.4049/jimmunol.09008 95">[More Information]</a> Nguyen, K., Zylicz, J., Szczesny, P., Sroka, A., Hunter, N., Potempa, J. (2009). Verification of a topology model of PorT as an integral outer-membrane protein in Porphyromonas gingivalis. Microbiology, 155(2), 328-337. <a href="http://dx.doi.org/10.1099/mic.0.024323-0" >[More Information]</a> 2008 Potempa, M., Potempa, J., Okroj, M., Popadiak, K., Eick, S., Nguyen, K., Riesbeck, K., Blom, A. (2008). Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis. The Journal of Immunology, 181(8), 5537-5544. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=18832711">[More Information]</a> Gao, J., Xie, H., Nguyen, K., Hunter, N. (2008). Detection and characterization of novel outer membrane proteins involved in heme binding by Porphyromonas gingivalis. Journal of Biotechnology, 136, S88. <a href="http://dx.doi.org/10.1016/j.jbiotec.2008.07 .199">[More Information]</a> 2007 Nguyen, K., Travis, J., Potempa, J. (2007). Does the importance of the c-terminal residues in the maturation of RgpB from Porphryomonas gingivalis reveal a novel mechanism for protein export in a subgroup of gram-negative bacteria? Journal of Bacteriology, 189(3), 833-843. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17142394">[More Information]</a> Potempa, J., Nguyen, K. (2007). Purification and characterisaztion of gingipains. Current Protocols in Protein Science, 21.20(Supplement 49), 1-27. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=18429320">[More Information]</a> Potempa, J., Nguyen, K. (2007). Purification and Characterization of Gingipains. In unknown (Eds.), Current Protocols in Protein Science Supplement 49, (pp. 21.21.1-21.20.27). online: John Wiley & Sons. 2006 Mydel, P., Takahashi, Y., Yumoto, H., Sztukowska, M., Kubica, M., Gibson III, F., Kurtz Jr, D., Travis, J., Collins, L., Nguyen, K., et al (2006). Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection. P L o S Pathogens, 2(7, e76), 0712-0725. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=16895445">[More Information]</a> 2004 Nadkarni, M., Nguyen, K., Chapple, C., DeCarlo, A., Jacques, N., Hunter, N. (2004). Distribution Of Porphyromonas Gingivalis Biotypes Defined By Alleles Of The Kgp (Lys-Gingipain) Gene. Journal of Clinical Microbiology, 42(8), 3873-3876. Nguyen, K., DeCarlo, A., Paramaesvaran, M., Collyer, C., Langley, D., Hunter, N. (2004). Humoral Responses To Porphyromonas gingivalis Gingipain Adhesin Domains In Subjects With Chronic Periodontitis. Infection and Immunity, 72(3), 1374-1382. 2003 Paramaesvaran, M., Nguyen, K., Caldon, E., McDonald, J., Najdi, S., Gonzaga, G., Langley, D., DeCarlo, A., Hunter, N., Crossley, M., Collyer, C. (2003). Porphyrin-mediated cell surface heme capture from hemoglobin by Porphyromanas gingivalis. Journal of Bacteriology, 185(8), 2528-2537. 2002 Hunter, N., Nguyen, K., McDonald, J., Quinn, M., Langley, D., Crossley, M., Collyer, C. (2002). Structural requirements for recognition of essential porphyrin by Porphyromonas gingivalis. Journal of Porphyrins and Phthalocyanines, 6(12), 774-782.