Publications for Ky-Anh Nguyen
Publications for Ky-Anh Nguyen
2016
de Diego, I., Ksiazek, M., Mizgalska, D.,
Koneru, L., Golik, P., Szmigielski, B., Nowak,
M., Nowakowska, Z., Potempa, B., Gao, J.,
Kwan, A., Trewhella, J., Nguyen, K., et al
(2016). The outer-membrane export signal of
Porphyromonas gingivalis type IX secretion
system (T9SS) is a conserved C-terminal
β-sandwich domain. Scientific Reports, 6, 1-17.
<a
href="http://dx.doi.org/10.1038/srep23123">[Mo
re Information]</a>
2015
Ramos-Junior, E., Morandini, A., Almeida da
Silva, C., Franco, E., Potempa, J., Nguyen, K.,
Oliveira, A., Zamboni, D., Ojcius, D.,
Scharfstein, J., et al (2015). A Dual Role for
P2X7 Receptor during Porphyromonas gingivalis
Infection. Journal of Dental Research, 94(9),
1233-1242. <a
href="http://dx.doi.org/10.1177/0022034515593
465">[More Information]</a>
Nadkarni, M., Chhour, K., Browne, G., Byun, R.,
Nguyen, K., Chapple, C., Jacques, N., Hunter, N.
(2015). Age-dependant changes in
porphyromonas gingivalis and prevotella
species/phylotypes in healthy gingiva and
inflamed/diseased sub-gingival sites. Clinical
Oral Investigations, 19(4), 911-919. <a
href="http://dx.doi.org/10.1007/s00784-014-130
1-7">[More Information]</a>
Veillard, F., Potempa, B., Guo, Y., Ksiazek, M.,
Sztukowska, M., Houston, J., Koneru, L.,
Nguyen, K., Potempaa, J. (2015). Purification
and characterisation of recombinant His-tagged
RgpB gingipain from Porphymonas gingivalis.
Biological Chemistry, 396(4), 377-384. <a
href="http://dx.doi.org/10.1515/hsz-2014-0304"
>[More Information]</a>
2014
Kianoush, N., Adler, C., Nguyen, K., Browne,
G., Simonian, M., Hunter, N. (2014). Bacterial
Profile of Dentine Caries and the Impact of pH
on Bacterial Population Diversity. PloS One,
9(3), 1-10. <a
href="http://dx.doi.org/10.1371/journal.pone.009
2940">[More Information]</a>
Siddiqui, H., Yoder-Himes, D., Mizgalska, D.,
Nguyen, K., Potempa, J., Olsen, I. (2014).
Genome Sequence of Porphyromonas gingivalis
Strain HG66 (DSM 28984). Genome
Announcements, 2(5), 1-2. <a
href="http://dx.doi.org/10.1128/genomeA.00947
-14">[More Information]</a>
Kianoush, N., Nguyen, K., Browne, G.,
Simonian, M., Hunter, N. (2014). pH gradient
and distribution of streptococci, lactobacilli,
prevotellae, and fusobacteria in carious dentine.
Clinical Oral Investigations, 18(2), 659-669. <a
href="http://dx.doi.org/10.1007/s00784-013-100
9-0">[More Information]</a>
Morandini, A., Ramos-Junior, E., Potempa, J.,
Nguyen, K., Oliveira, A., Bellio, M., Ojcius, D.,
Scharfstein, J., Coutinho-Silva, R. (2014).
Porphyromonas gingivalis Fimbriae Dampen
P2X7-Dependent Interleukin-1B Secretion.
Journal of Innate Immunity, 6(6), 831-845. <a
href="http://dx.doi.org/10.1159/000363338">[M
ore Information]</a>
Nadkarni, M., Chhour, K., Chapple, C., Nguyen,
K., Hunter, N. (2014). The profile of
Porphyromonas gingivalis kgp biotype and
firmA genotype mosaic in subgingival plaque
samples. FEMS Microbiology Letters, 361(2),
190-194. <a
href="http://dx.doi.org/10.1111/1574-6968.1263
1">[More Information]</a>
2013
Nguyen, K., Potempa, J. (2013). Gingipain R.
In Neil D. Rawlings, Guy Salvesen (Eds.),
Handbook of Proteolytic Enzymes: Volume 3,
(pp. 2328-2336). London, United Kingdom:
Elsevier.
Pyrc, K., Milewska, A., Kantyka, T., Sroka, A.,
Maresz, K., Koziel, J., Nguyen, K., Enghild, J.,
Knudsen, A., Potempaa, J. (2013). Inactivation
of Epidermal Growth Factor by Porphyromonas
gingivalis as a Potential Mechanism for
Periodontal Tissue Damage. Infection and
Immunity, 81(1), 55-64. <a
href="http://dx.doi.org/10.1128/IAI.00830-12">[
More Information]</a>
Veillard, F., Sztukowska, M., Mizgalska, D.,
Ksiazek, M., Houston, J., Potempa, B., Enghild,
J., Thogersen, I., Gomis-Ruth, F., Nguyen, K., et
al (2013). Inhibition of gingipains by their
profragments as the mechanism protecting
porphyromonas gingivalis against premature
activation of secreted proteases. Biochimica et
Biophysica Acta. General Subjects, 1830 (8),
4218-4228. <a
href="http://dx.doi.org/10.1016/j.bbagen.2013.04
.005">[More Information]</a>
Maresz, K., Hellvard, A., Sroka, A., Adamowicz,
K., Bielecka, E., Koziel, J., Gawron, K.,
Mizgalska, D., Marcinska, K., Benedyk, M.,
Nguyen, K., et al (2013). Porphyromonas
gingivalis facilitates the development and
progression of destructive arthritis through its
unique bacterial peptidylarginine deiminase
(PAD). PLoS Pathogens, 9(9), 1-10. <a
href="http://dx.doi.org/10.1371/journal.ppat.100
3627">[More Information]</a>
Publications for Ky-Anh Nguyen
Zhou, X., Gao, J., Hunter, N., Potempa, J.,
Nguyen, K. (2013). Sequence-independent
processing site of the C-terminal domain (CTD)
influences maturation of the RgpB protease from
Porphyromonas gingivalis. Molecular
Microbiology, 89(5), 903-917. <a
href="http://dx.doi.org/10.1111/mmi.12319">[M
ore Information]</a>
2012
Sztukowska, M., Veillard, F., Potempa, B.,
Bogyo, M., Enghild, J., Thogersen, I., Nguyen,
K., Potempa, J. (2012). Disruption of gingipain
oligomerization into non-covalent cell-surface
attached complexes. Biological Chemistry,
393(9), 971-977. <a
href="http://dx.doi.org/10.1515/hsz-2012-0175"
>[More Information]</a>
Nadkarni, M., Browne, G., Chhour, K., Byun, R.,
Nguyen, K., Chapple, C., Jacques, N., Hunter, N.
(2012). Pattern of distribution of Prevotella
species/phylotypes associated with healthy
gingiva and periodontal disease. European
Journal of Clinical Microbiology and Infectious
Diseases, 31(11), 2989-2999. <a
href="http://dx.doi.org/10.1007/s10096-012-165
1-5">[More Information]</a>
Gao, J., Lu, Y., Browne, G., Yap, B., Trewhella,
J., Hunter, N., Nguyen, K. (2012). The role of
heme-binding by DNA-protective protein from
starved-cells (Dps) in the tolerance of
Porphyromonas gingivalis to heme toxicity.
Journal of Biological Chemistry, 287(50),
42243-42258. <a
href="http://dx.doi.org/10.1074/jbc.M112.39278
7">[More Information]</a>
2011
Rapala-Kozik, M., Bras, G., Karkowska-Kuleta,
J., Sroka, A., Herwald, H., Nguyen, K., Eick, S.,
Potempa, J., Kozik, A. (2011). Adsorption of
Components of the Plasma Kinin-forming
System on the Surface of Porphyromonas
gingivalis Involves Gingipains as the Major
Docking Platforms. Infection and Immunity,
79(2), 797-805. <a
href="http://dx.doi.org/10.1128/IAI.00966-10">[
More Information]</a>
Cerda-Costa, N., Guevara, T., Karim, A.,
Ksiazek, M., Nguyen, K., Arolas, J., Potempa, J.,
Gomis-Ruth, F. (2011). The structure of the
catalytic domain of Tannerella forsythia karilysin
reveals it is a bacterial xenologue of animal
matrix metalloproteinases. Molecular
Microbiology, 79(1), 119-132. <a
href="http://dx.doi.org/10.1111/j.1365-2958.201
0.07434.x">[More Information]</a>
2010
Karim, A., Kulczycka, M., Kantyka, T., Dubin,
G., Jabaiah, A., Daugherty, P., Thogerson, I.,
Enghild, J., Nguyen, K., Potempa, J. (2010). A
novel matrix metalloprotease-like enzyme
(karilysin) of the periodontal pathogen
Tannerella forsythia ATCC 43037. Biological
Chemistry, 391(1), 105-117. <a
href="http://dx.doi.org/10.1515/BC.2010.009">[
More Information]</a>
Mostofi Zadeh Farahani, R., Nguyen, K.,
Simonian, M., Hunter, N. (2010). Adaptive
calcified matrix response of dental pulp to
bacterial invasion in associated with
establishment of a network of Glial Fibrillary
Acidic Protein+/Glutamine Synthetase+ Cells.
The American Journal of Pathology, 177(4),
1901-1914. <a
href="http://dx.doi.org/10.2353/ajpath.2010.1000
73">[More Information]</a>
Gao, J., Nguyen, K., Hunter, N. (2010).
Characterization of a hemophore-like protein
from Porphyromonas gingivalis. Journal of
Biological Chemistry, 285(51), 40028-40038. <a
href="http://dx.doi.org/10.1074/jbc.M110.16353
5">[More Information]</a>
Guo, Y., Nguyen, K., Potempa, J. (2010).
Dichotomy of gingipains action as virulance
factors: from cleaving substrates with the
precision of a surgeon's knife to a meat
chopper-like brutal degradation of proteins.
Periodontology 2000, 54, 15-44. <a
href="http://dx.doi.org/10.1111/j.1600-0757.201
0.00377.x">[More Information]</a>
Wegner, N., Wait, R., Sroka, A., Eick, S.,
Nguyen, K., Lundberg, K., Kinloch, A.,
Culshaw, S., Potempa, J., Venables, P. (2010).
Peptidylarginine Deiminase From
Porphyromonas gingivalis Citrullinates Human
Fibrinogen and alpha-Enolase. Arthritis &
Rheumatology, 62(9), 2662-2672. <a
href="http://dx.doi.org/10.1002/art.27552">[Mor
e Information]</a>
Koziel, J., Karim, A., Przbyszewska, K.,
Ksiazek, M., Rapala-Kozik, M., Nguyen, K.,
Potempa, J. (2010). Proteolytic inactivation of
LL-37 by Karilysin, a Novel Virulence
Mechanism of Tannerella forsythia. Journal of
Innate Immunity, 2(3), 288-293. <a
href="http://dx.doi.org/10.1159/000281881">[M
ore Information]</a>
Li, N., Yun, P., Nadkarni, M., Nazila, B.,
Nguyen, K., Lee, M., Hunter, N., Collyer, C.
(2010). Structure determination and analysis of a
haemolytic gingipain adhesin domain from
Porphyromonas gingivalis. Molecular
Microbiology, 76(4), 861-873. <a
href="http://dx.doi.org/10.1111/j.1365-2958.201
0.07123.x">[More Information]</a>
Publications for Ky-Anh Nguyen
2009
Gao, J., Nguyen, K., Hunter, N. (2009). A novel
haem uptake in Porphyromonas gingivalis.
Journal of Dental Research.
Potempa, M., Potempa, J., Kantyka, T., Nguyen,
K., Wawrzonek, K., Manandhar, S., Popadiak,
K., Riesbeck, K., Eick, S., Blom, A. (2009).
Interpain A, a Cysteine Proteinase from
Prevotella intermedia, Inhibits Complement by
Degrading Complement Factor C3. P L o S
Pathogens, 5(2), e1000316-1-e1000316-14. <a
href="http://dx.doi.org/10.1371/journal.ppat.100
0316">[More Information]</a>
Monteiro, A., Scovino, A., Raposo, S., Gaze, V.,
Cruz, C., Svensjo, E., Narciso, M., Colombo, A.,
Pesquero, J., Feres-Filho, E., Nguyen, K. (2009).
Kinin Danger Signals Proteolytically Released
by Gingipain Induce Fimbriae-Specific IFN-and IL-17-Producing T Cells in Mice Infected
Intramucosally with Porphyromonas Gingivalis.
The Journal of Immunology, 183(183),
3700-3711. <a
href="http://dx.doi.org/10.4049/jimmunol.09008
95">[More Information]</a>
Nguyen, K., Zylicz, J., Szczesny, P., Sroka, A.,
Hunter, N., Potempa, J. (2009). Verification of a
topology model of PorT as an integral
outer-membrane protein in Porphyromonas
gingivalis. Microbiology, 155(2), 328-337. <a
href="http://dx.doi.org/10.1099/mic.0.024323-0"
>[More Information]</a>
2008
Potempa, M., Potempa, J., Okroj, M., Popadiak,
K., Eick, S., Nguyen, K., Riesbeck, K., Blom, A.
(2008). Binding of complement inhibitor
C4b-binding protein contributes to serum
resistance of Porphyromonas gingivalis. The
Journal of Immunology, 181(8), 5537-5544. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=18832711">[More Information]</a>
Gao, J., Xie, H., Nguyen, K., Hunter, N. (2008).
Detection and characterization of novel outer
membrane proteins involved in heme binding by
Porphyromonas gingivalis. Journal of
Biotechnology, 136, S88. <a
href="http://dx.doi.org/10.1016/j.jbiotec.2008.07
.199">[More Information]</a>
2007
Nguyen, K., Travis, J., Potempa, J. (2007). Does
the importance of the c-terminal residues in the
maturation of RgpB from Porphryomonas
gingivalis reveal a novel mechanism for protein
export in a subgroup of gram-negative bacteria?
Journal of Bacteriology, 189(3), 833-843. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17142394">[More Information]</a>
Potempa, J., Nguyen, K. (2007). Purification and
characterisaztion of gingipains. Current
Protocols in Protein Science, 21.20(Supplement
49), 1-27. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=18429320">[More Information]</a>
Potempa, J., Nguyen, K. (2007). Purification and
Characterization of Gingipains. In unknown
(Eds.), Current Protocols in Protein Science
Supplement 49, (pp. 21.21.1-21.20.27). online:
John Wiley & Sons.
2006
Mydel, P., Takahashi, Y., Yumoto, H.,
Sztukowska, M., Kubica, M., Gibson III, F.,
Kurtz Jr, D., Travis, J., Collins, L., Nguyen, K.,
et al (2006). Roles of the host oxidative immune
response and bacterial antioxidant rubrerythrin
during Porphyromonas gingivalis infection. P L
o S Pathogens, 2(7, e76), 0712-0725. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16895445">[More Information]</a>
2004
Nadkarni, M., Nguyen, K., Chapple, C.,
DeCarlo, A., Jacques, N., Hunter, N. (2004).
Distribution Of Porphyromonas Gingivalis
Biotypes Defined By Alleles Of The Kgp
(Lys-Gingipain) Gene. Journal of Clinical
Microbiology, 42(8), 3873-3876.
Nguyen, K., DeCarlo, A., Paramaesvaran, M.,
Collyer, C., Langley, D., Hunter, N. (2004).
Humoral Responses To Porphyromonas
gingivalis Gingipain Adhesin Domains In
Subjects With Chronic Periodontitis. Infection
and Immunity, 72(3), 1374-1382.
2003
Paramaesvaran, M., Nguyen, K., Caldon, E.,
McDonald, J., Najdi, S., Gonzaga, G., Langley,
D., DeCarlo, A., Hunter, N., Crossley, M.,
Collyer, C. (2003). Porphyrin-mediated cell
surface heme capture from hemoglobin by
Porphyromanas gingivalis. Journal of
Bacteriology, 185(8), 2528-2537.
2002
Hunter, N., Nguyen, K., McDonald, J., Quinn,
M., Langley, D., Crossley, M., Collyer, C.
(2002). Structural requirements for recognition
of essential porphyrin by Porphyromonas
gingivalis. Journal of Porphyrins and
Phthalocyanines, 6(12), 774-782.