Publications for Michael Kassiou
Publications for Michael Kassiou
2016
Thomas, C., Vercouillie, J., Domene, A., Tauber,
C., Kassiou, M., Guilloteau, D., Destrieux, C.,
Serriere, S., Chalon, S. (2016). Detection of
neuroinflammation in a rat model of
subarachnoid hemorrhage using [18F]DPA-714
PET imaging. Molecular Imaging, 15, 1-8. <a
href="http://dx.doi.org/10.1177/1536012116639
189">[More Information]</a>
Jorgensen, W., Gulliver, D., Werry, E., Reekie,
T., Connor, M., Kassiou, M. (2016). Flexible
analogues of WAY-267,464: Synthesis and
pharmacology at the human oxytocin and
vasopressin 1a receptors. European Journal of
Medicinal Chemistry, 108, 730-740. <a
href="http://dx.doi.org/10.1016/j.ejmech.2015.11
.050">[More Information]</a>
Coughlin, J., Wang, Y., Ambinder, E., Ward, R.,
Minn, I., Vranesic, M., Kim, P., Ford, C., Higgs,
C., Hayes, L., Kassiou, M., et al (2016). In vivo
markers of inflammatory response in
recent-onset schizophrenia: a combined study
using [11C]DPA-713 PET and analysis of CSF
and plasma. Translational Psychiatry, 6,
e777-1-e777-8. <a
href="http://dx.doi.org/10.1038/tp.2016.40">[M
ore Information]</a>
Dupont, A., Guilloteau, D., Kassiou, M., Ribeiro,
M., Vercouillie, J., Katsifis, A., Arlicot, N.
(2016). Radiopharmaceuticals for PET imaging
of neuroinflammation. Medecine Nucleaire,
40(1), 72-81. <a
href="http://dx.doi.org/10.1016/j.mednuc.2016.0
1.001">[More Information]</a>
Longworth, M., Banister, S., Mack, J., Glass, M.,
Connor, M., Kassiou, M. (2016). The
2-alkyl-2H-indazole regioisomers of synthetic
cannabinoids AB-CHMINACA,
AB-FUBINACA, AB-PINACA, and
5F-AB-PINACA are possible manufacturing
impurities with cannabimimetic activities.
Forensic Toxicology, 34(2), 286-303. <a
href="http://dx.doi.org/10.1007/s11419-016-031
6-y">[More Information]</a>
Katte, T., Reekie, T., Jorgensen, W., Kassiou, M.
(2016). The formation of seven-membered
heterocycles under mild Pictet-Spengler
conditions: A route to
pyrazolo[3,4]benzodiazepines. The Journal of
Organic Chemistry, 81(11), 4883-4889. <a
href="http://dx.doi.org/10.1021/acs.joc.6b00710"
>[More Information]</a>
Beinat, C., Banister, S., Herrera, M., Kassiou, M.
(2016). The recent development of α7 nicotinic
acetylcholine receptor (nAChR) ligands as
therapeutic candidates for the treatment of
central nervous system (CNS) diseases. Current
Pharmaceutical Design, 22(14), 2134-2151. <a
href="http://dx.doi.org/10.2174/1381612822666
160127114125#sthash.Bm5P9qQ9">[More
Information]</a>
2015
Serriere, S., Tauber, C., Vercouillie, J., Mothes,
C., Pruckner, C., Guilloteau, D., Kassiou, M.,
Domene, A., Garreau, L., Page, G., et al (2015).
Amyloid load and translocator protein 18 kDa in
APPswePS1-dE9 mice: a longitudinal study.
Neurobiology of Aging, 36(4), 1639-1652. <a
href="http://dx.doi.org/10.1016/j.neurobiolaging.
2014.11.023">[More Information]</a>
Wilkinson, S., Banister, S., Kassiou, M. (2015).
Bioisosteric fluorine in the clandestine design of
synthetic cannabinoids. Australian Journal of
Chemistry, 68(1), 4-8. <a
href="http://dx.doi.org/10.1071/CH14198">[Mor
e Information]</a>
Austin, C., Moir, M., Kahlert, J., Smith, J.,
Jamie, J., Kassiou, M., Rendina, L. (2015).
Carborane-containing hydroxyamidine scaffolds
as novel inhibitors of indoleamine
2,3-dioxygenase 1 (IDO1). Australian Journal of
Chemistry, 68(12), 1866-1870. <a
href="http://dx.doi.org/10.1071/CH15489">[Mor
e Information]</a>
Abbassi, R., Johns, T., Kassiou, M., Munoz, L.
(2015). DYRK1A in neurodegeneration and
cancer: Molecular basis and clinical implications.
Pharmacology & Therapeutics, 151, 87-98. <a
href="http://dx.doi.org/10.1016/j.pharmthera.201
5.03.004">[More Information]</a>
Banister, S., Stuart, J., Kevin, R., Edington, A.,
Longworth, M., Wilkinson, S., Beinat, C.,
Buchanan, A., Hibbs, D., Glass, M., McGregor,
I., Kassiou, M., et al (2015). Effects of
Bioisosteric Fluorine in Synthetic Cannabinoid
Designer Drugs JWH-018, AM-2201, UR-144,
XLR-11, PB-22, 5F-PB-22, APICA, and
STS-135. ACS Chemical Neuroscience, 6(8),
1445-1458. <a
href="http://dx.doi.org/10.1021/acschemneuro.5
b00107">[More Information]</a>
Banister, S., Beinat, C., Wilkinson, S., Shen, B.,
Bartoli, C., Selleri, S., Da Pozzo, E., Martini, C.,
Chin, F., Kassiou, M. (2015). Ether analogues of
DPA-714 with subnanomolar affinity for the
translocator protein (TSPO). European Journal
of Medicinal Chemistry, 93, 392-400.
Santiago-Ribeiro, M., Vercouillie, J., Cottier, J.,
Debiais, S., Bonnaud, I., Annan, M., Maia, S.,
Kassiou, M., Arlicot, N., Guilloteau, D. (2015).
Evaluation en TEP de l'activation microgliale
apres un accident vasculaire cerebral. Medecine
Nucleaire, 39(3), 210-210. <a
Publications for Michael Kassiou
href="http://dx.doi.org/10.1016/j.mednuc.2015.0
3.017">[More Information]</a>
href="http://dx.doi.org/10.1016/j.bcp.2015.10.01
4">[More Information]</a>
Narlawar, R., Werry, E., Scarf, A., Hanani, R.,
Chua, S., King, V., Barron, M., Martins, R.,
Ittner, L., Rendina, L., Kassiou, M. (2015). First
demonstration of positive allosteric-like
modulation at the human wild type translocator
protein (TSPO). Journal of Medicinal Chemistry,
58(21), 8743-8749. <a
href="http://dx.doi.org/10.1021/acs.jmedchem.5b
01288">[More Information]</a>
Manohar, M., Banister, S., Beinat, C.,
O'Brien-Brown, J., Kassiou, M. (2015). Recent
advances in the development of sigma-1 receptor
ligands. Australian Journal of Chemistry, 68,
600-609. <a
href="http://dx.doi.org/10.1071/CH14590">[Mor
e Information]</a>
Lee, D., Yue, X., Ibrahim, W., Lentz, M.,
Peterson, K., Jagoda, E., Kassiou, M., Maric, D.,
Reid, W., Hammoud, D. (2015). Lack of
neuroinflammation in the HIV-1 transgenic rat:
an [18F]-DPA714 PET imaging study. Journal
of Neuroinflammation, 12(171), 1-11. <a
href="http://dx.doi.org/10.1186/s12974-015-039
0-9">[More Information]</a>
Coughlin, J., Wang, Y., Munro, C., Ma, S., Yue,
C., Chen, S., Airan, R., Kim, P., Adams, A.,
Garcia, C., Kassiou, M., et al (2015).
Neuroinflammation and brain atrophy in former
NFL players: An in vivo multimodal imaging
pilot study. Neurobiology of Disease, 74, 58-65.
<a
href="http://dx.doi.org/10.1016/j.nbd.2014.10.01
9">[More Information]</a>
Munoz, L., Kavanagh, M., Phoa, A., Heng, B.,
Dzamko, N., Chen, E., Doddareddy, M.,
Guillemin, G., Kassiou, M. (2015). Optimisation
of LRRK2 inhibitors and assessment of
functional efficacy in cell-based models of
neuroinflammation. European Journal of
Medicinal Chemistry, 95, 29-34. <a
href="http://dx.doi.org/10.1016/j.ejmech.2015.03
.003">[More Information]</a>
Banister, S., Moir, M., Stuart, J., Kevin, R.,
Wood, K., Longworth, M., Wilkinson, S., Beinat,
C., Buchanan, A., Glass, M., McGregor, I.,
Kassiou, M., et al (2015). Pharmacology of
indole and indazole synthetic cannabinoid
designer drugs AB-FUBINACA,
ADB-FUBINACA, AB-PINACA,
ADB-PINACA, 5F-AB-PINACA,
5F-ADB-PINACA, ADBICA, and 5F-ADBICA.
ACS Chemical Neuroscience, 6(9), 1546-1559.
<a
href="http://dx.doi.org/10.1021/acschemneuro.5
b00112">[More Information]</a>
Phoa, A., Brown, S., Gurgis, F., Akerfeldt, M.,
Döbber, A., Renn, C., Peifer, C., Stringer, B.,
Day, B., Wong, C., Chircop (nee Fabbro), M.,
Kassiou, M., Munoz, L., et al (2015).
Pharmacology of novel small-molecule tubulin
inhibitors in glioblastoma cells with enhanced
EGFR signalling. Biochemical Pharmacology,
98(4), 587-601. <a
Beinat, C., Reekie, T., Banister, S.,
O'Brien-Brown, J., Xie, T., Olson, T., Xiao, Y.,
Harvey, A., O'Connor, S., Coles, C., Kassiou,
M., et al (2015). Structure-activity relationship
studies of SEN12333 analogues: Determination
of the optimal requirements for binding affinities
at alpha7 nAChRs through incorporation of
known structural motifs. European Journal of
Medicinal Chemistry, 95, 277-301. <a
href="http://dx.doi.org/10.1016/j.ejmech.2015.03
.025">[More Information]</a>
Banister, S., Stuart, J., Conroy, T., Longworth,
M., Manohar, M., Beinat, C., Wilkinson, S.,
Kevin, R., Hibbs, D., Glass, M., McGregor, I.,
Kassiou, M., et al (2015). Structure-activity
relationships of synthetic cannabinoid designer
drug RCS-4 and its regioisomers and C4
homologues. Forensic Toxicology, 33(2),
355-366. <a
href="http://dx.doi.org/10.1007/s11419-015-028
2-9">[More Information]</a>
Beinat, C., Banister, S., Herrera, M., Law, V.,
Kassiou, M. (2015). The therapeutic potential of
alpha7 nicotinic acetylcholine receptor (apha7
nAChR) agonists for the treatment of the
cognitive deficits associated with schizophrenia.
CNS Drugs.
Werry, E., Barron, M., Kassiou, M. (2015).
TSPO as a target for glioblastoma therapeutics.
Biochemical Society Transactions, 43, 531-536.
<a
href="http://dx.doi.org/10.1042/BST20150015">
[More Information]</a>
Hicks, C., Ramos, L., Reekie, T., Narlawar, R.,
Kassiou, M., McGregor, I. (2015). WAY
267,464, a non-peptide oxytocin receptor
agonist, impairs social recognition memory in
rats through a vasopressin 1A receptor antagonist
action. Psychopharmacology, 232, 2659-2667.
<a
href="http://dx.doi.org/10.1007/s00213-015-390
2-5">[More Information]</a>
2014
Medran-Navarrete, V., Bernards, N., Kuhnast,
B., Damont, A., Pottier, G., Peyronneau, M.,
Kassiou, M., Marguet, F., Puech, F., Boisgard,
R., et al (2014). [18F]DPA-C5yne, a novel
fluorine-18-labelled analogue of DPA-714:
Publications for Michael Kassiou
radiosynthesis and preliminary evaluation as a
radiotracer for imaging neuroinflammation with
PET. Journal of Labelled Compounds and
Radiopharmaceuticals, 57(6), 410-418. <a
href="http://dx.doi.org/10.1002/jlcr.3199">[Mor
e Information]</a>
Liang, V., Ullrich, M., Lam, H., Chew, Y.,
Banister, S., Song, X., Zaw, T., Kassiou, M.,
Goetz, J., Nicholas, H. (2014). Altered
proteostasis in aging and heat shock response in
C. elegans revealed by analysis of the global and
de novo synthesized proteome. Cellular and
Molecular Life Sciences, 71(17), 3339-3361. <a
href="http://dx.doi.org/10.1007/s00018-014-155
8-7">[More Information]</a>
Ullrich, M., Liang, V., Chew, Y., Banister, S.,
Song, X., Zaw, T., Lam, H., Berber, S., Kassiou,
M., Nicholas, H., Goetz, J. (2014).
Bio-orthogonal labeling as a tool to visualize and
identify newly synthesized proteins in
Caenorhabditis elegans. Nature Protocols, 9(9),
2237-2255. <a
href="http://dx.doi.org/10.1038/nprot.2014.150"
>[More Information]</a>
Hicks, C., Ramos, L., Reekie, T., Misagh, G.,
Narlawar, R., Kassiou, M., McGregor, I. (2014).
Body temperature and cardiac changes induced
by peripherally administered oxytocin,
vaspressin and the non-peptide oxytocin receptor
agonist WAY 267, 464: a biotelemetry study in
rats. British Journal of Pharmacology, 171(11),
2868-2887. <a
href="http://dx.doi.org/10.1111/bph.12613">[Mo
re Information]</a>
Ribeiro, M., Vercouillie, J., Debiais, S., Cottier,
J., Bonnaud, I., Camus, V., Banister, S., Kassiou,
M., Arlicot, N., Guilloteau, D. (2014). Could 18F
DPA 714 PET imaging be interesting to use in
the early post-stroke period? European Journal
of Nuclear Medicine and Molecular Imaging,
4(28), 1-8. <a
href="http://dx.doi.org/10.1186/s13550-014-002
8-4">[More Information]</a>
Zavitsanou, K., Lim, C., Purves-Tyson, T., Karl,
T., Kassiou, M., Banister, S., Guillemin, G.,
Shannon Weickert, C. (2014). Effect of maternal
immune activation on the kynurenine pathway in
preadolescent rat offspring and on
MK801-induced hyperlocomotion in adulthood:
Amelioration by COX2 inhibition. Brain,
Behavior, and Immunity, 41, 173-181. <a
href="http://dx.doi.org/10.1016/j.bbi.2014.05.01
1">[More Information]</a>
Beinat, C., Reekie, T., Hibbs, D., Xie, T., Olson,
T., Xiao, Y., Harvey, A., O'Connor, S., Coles,
C., Tsanaktsidis, J., Kassiou, M. (2014).
Investigations of amide bond variation and biaryl
modification in analogues of alpha7 nAChR
agonist SEN12333. European Journal of
Medicinal Chemistry, 84, 200-205. <a
href="http://dx.doi.org/10.1016/j.ejmech.2014.07
.029">[More Information]</a>
Barron, M., Werry, E., McGregor, I., Kassiou,
M. (2014). P2X7 in Bipolar and Depressive
Disorders. In Norbert Weiss, Alexandra
Koschak (Eds.), Pathologies of Calcium
Channels, (pp. 635-661). Berlin:
Springer-Verlag.
Gent, Y., Weijers, K., Molthoff, C., Windhorst,
A., Huisman, M., Kassiou, M., Jansen, G.,
Lammertsma, A., van der Laken, C. (2014).
Promising potential of new generation
translocator protein tracers providing enhanced
contrast of arthritis imaging by positron emission
tomography in a rat model of arthritis. Arthritis
Research & Therapy, 16(2), 1-9. <a
href="http://dx.doi.org/10.1186/ar4509">[More
Information]</a>
Reekie, T., McGregor, I., Kassiou, M. (2014).
Pyrazolo 1,4 diazepines as non-peptidic probes
of the oxytocin and vasopressin receptors.
Tetrahedron Letters, 55(33), 4568-4571. <a
href="http://dx.doi.org/10.1016/j.tetlet.2014.06.0
22">[More Information]</a>
Coughlin, J., Wang, Y., Ma, S., Yue, C., Kim, P.,
Adams, A., Roosa, H., Gage, K., Stathis, M.,
Rais, R., Kassiou, M., et al (2014). Regional
brain distribution of translocator protein using
11C DPA-713 PET in individuals infected with
HIV. Journal of neurovirology, 20(3), 219-232.
<a
href="http://dx.doi.org/10.1007/s13365-014-023
9-5">[More Information]</a>
Beinat, C., Banister, S., Hoban, J., Tsanaktsidis,
J., Metaxas, A., Windhorst, A., Kassiou, M.
(2014). Structure-activity relationships of
N-substituted 4-(trifluoromethoxyl)benzamidines
with affinity for GluN2B-containing NMDA
receptors. Bioorganic & Medicinal Chemistry
Letters, 24(3), 828-830. <a
href="http://dx.doi.org/10.1016/j.bmcl.2013.12.0
87">[More Information]</a>
Wilkinson, S., Gunosewoyo, H., Barron, M.,
Boucher, A., McDonnell, M., Turner, P.,
Morrison, D., Bennett, M., McGregor, I.,
Rendina, L., Kassiou, M. (2014). The first
CNS-active carborane: A novel P2X7 receptor
antagonist with antidepressant activity. ACS
Chemical Neuroscience, 5(5), 335-339. <a
href="http://dx.doi.org/10.1021/cn500054n">[M
ore Information]</a>
Chua, S., Kassiou, M., Ittner, L. (2014). The
translocator protein as a drug target in
Alzheimer's disease. Expert Review of
Neurotherapeutics, 14(4), 439-448. <a
href="http://dx.doi.org/10.1586/14737175.2014.
Publications for Michael Kassiou
896201">[More Information]</a>
2013
Boutin, H., Prenant, C., Maroy, R., Galea, J.,
Greenhalgh, A., Smigova, A., Cawthorne, C.,
Julyan, P., Wilkinson, S., Banister, S., Kassiou,
M., et al (2013). [(18)F]DPA-714: Direct
comparison with [(11)C]PK11195 in a model of
cerebral ischemia in rats. PloS One, 8673 (2),
1-9. <a
href="http://dx.doi.org/10.1371/journal.pone.005
6441">[More Information]</a>
Beinat, C., Banister, S., McErlean, C., Kassiou,
M. (2013). A practical synthesis of
(1S,4S)-2,5-diazabicyclo[2.2.1]heptane.
Tetrahedron Letters, 54(39), 5345-5347. <a
href="http://dx.doi.org/10.1016/j.tetlet.2013.07.0
92">[More Information]</a>
Ramos, L., Hicks, C., Kevin, R., Caminer, A.,
Narlawar, R., Kassiou, M., McGregor, I. (2013).
Acute Prosocial Effects of Oxytocin and
Vasopressin When Given Alone or in
Combination with
3,4-Methylenedioxymethamphetamine in Rats:
Involvement of the VI(A) Receptor.
Neuropsychopharmacology, 38(11), 2249-2259.
<a
href="http://dx.doi.org/10.1038/npp.2013.125">[
More Information]</a>
Ribeiro, M., Vercouillie, J., Corcia, P., Arlicot,
N., Erra, B., Maia, S., Bonnaud, I., Debiais, S.,
Kassiou, M., Guilloteau, D. (2013). Cerebral
biodistribution of the PET TSPO radioligand,
(18)F-DPA-714, in acute and chronic brain
diseases. Journal of Labelled Compounds and
Radiopharmaceuticals, 56(S1), P219-P219.
Wilkinson, S., Price, J., Kassiou, M. (2013).
Improved accessibility to the desoxy analogues
of delta(9)-tetrahydrocannabinol and
cannabidiol. Tetrahedron Letters, 54(1), 52-54.
<a
href="http://dx.doi.org/10.1016/j.tetlet.2012.10.0
80">[More Information]</a>
Schollhorn-Peyronneau, M., Saba, W., Goutal,
S., Damont, A., Dolle, F., Kassiou, M.,
Bottlaender, M., Valette, H. (2013). Metabolism
and quantification of [(18)F]DPA-714, a new
TSPO positron emission tomography
radioligand. Drug Metabolism and Disposition,
41(1), 122-131. <a
href="http://dx.doi.org/10.1124/dmd.112.046342
">[More Information]</a>
Santiago-Ribeiro, M., Vercouillie, J., Cottier, J.,
Debiais, S., Bonnaud, I., Arlicot, N., Erra, B.,
Maia, S., Kassiou, M., Guilloteau, D. (2013).
Microglia activation after acute stroke
demonstrated using 18F-DPA-714 PET.
Correlation with MRI. European Journal of
Nuclear Medicine and Molecular Imaging,
40(S2), S208-S208. <a
href="http://dx.doi.org/10.1007/s00259-013-253
5-3">[More Information]</a>
Banister, S., Manoli, M., Barron, M., Werry, E.,
Kassiou, M. (2013). N-substituted
8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]un
decanes as sigma receptor ligands with potential
neuroprotective effects. Bioorganic and
Medicinal Chemistry, 21(19), 6038-6052. <a
href="http://dx.doi.org/10.1016/j.bmc.2013.07.0
45">[More Information]</a>
Reekie, T., Kavanagh, M., Longworth, M.,
Kassiou, M. (2013). Synthesis of Biologically
Active Seven-Membered-Ring Heterocycles.
Synthesis: journal of synthetic organic chemistry,
45(23), 3211-3227. <a
href="http://dx.doi.org/10.1055/s-0033-1338549
">[More Information]</a>
Kavanagh, M., Doddareddy, M., Kassiou, M.
(2013). The development of CNS-active LRRK2
inhibitors using property-directed optimisation.
Bioorganic & Medicinal Chemistry Letters,
23(13), 3690-3696. <a
href="http://dx.doi.org/10.1016/j.bmcl.2013.04.0
86">[More Information]</a>
Banister, S., Manoli, M., Kassiou, M. (2013).
The development of radiotracers for imaging
sigma receptors in the central nervous system
(CNS) using positron emission tomography
(PET). Journal of Labelled Compounds and
Radiopharmaceuticals, 56(3-4), 215-224. <a
href="http://dx.doi.org/10.1002/jlcr.3010">[Mor
e Information]</a>
Kahlert, J., Austin, C., Kassiou, M., Rendina, L.
(2013). The fifth element in drug design: Boron
in medicinal chemistry. Australian Journal of
Chemistry, 66(10), 1118-1123. <a
href="http://dx.doi.org/10.1071/CH13256">[Mor
e Information]</a>
Banister, S., Wilkinson, S., Longworth, M.,
Stuart, J., Apetz, N., English, K., Brooker, L.,
Goebel, C., Hibbs, D., Glass, M., McGregor, I.,
Kassiou, M., et al (2013). The Synthesis and
Pharmacological Evaluation of
Adamantane-Derived Indoles: Cannabimimetic
Drugs of Abuse. ACS Chemical Neuroscience,
4(7), 1081-1092. <a
href="http://dx.doi.org/10.1021/cn400035r">[M
ore Information]</a>
Austin, C., Kahlert, J., Kassiou, M., Rendina, L.
(2013). The translocator protein (TSPO): A
novel target for cancer chemotherapy. The
International Journal of Biochemistry and Cell
Biology, 45(7), 1212-1216. <a
href="http://dx.doi.org/10.1016/j.biocel.2013.03.
004">[More Information]</a>
Publications for Michael Kassiou
Kassiou, M., James, M., Luus, C. (2013).
Translocator Protein Ligands (USA). Patent
No. 8492379.
2012
Banister, S., Rendina, L., Kassiou, M. (2012).
7-azabicyclo[2.2.1]heptane as a scaffold for the
development of selective sigma-2 (sigma-2)
receptor ligands. Bioorganic and Medicinal
Chemistry Letters: the tetrahedron journal for
research at the interface of chemistry and
biology, 22(12), 4059-4063. <a
href="http://dx.doi.org/10.1016/j.bmcl.2012.04.0
77">[More Information]</a>
Banister, S., Wilkinson, S., Hanani, R.,
Reynolds, A., Hibbs, D., Kassiou, M. (2012). A
practical, multigram synthesis of the
2-(2-(4-alkoxyphenyl)-5,7-dimethylpy-razolo[1,5
-a]pyrimidin-3-yl)acetamide (DPA) class of high
affinity translocator protein (TSPO) ligands.
Tetrahedron Letters, 53(29), 3780-3783. <a
href="http://dx.doi.org/10.1016/j.tetlet.2012.05.0
44">[More Information]</a>
Banister, S., Manoli, M., Doddareddy, M.,
Hibbs, D., Kassiou, M. (2012). A σ1 receptor
pharmacophore derived from a series of
N-substituted
4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,1
1)]dodecan-3-ols (AHDS). Bioorganic &
Medicinal Chemistry Letters, 22(19), 6053-6058.
<a
href="http://dx.doi.org/10.1016/j.bmcl.2012.08.0
46">[More Information]</a>
Beinat, C., Banister, S., Prehn, S., Doddareddy,
M., Hibbs, D., Sako, M., Chebib, M., Tran, T.,
Al-Muhtasib, N., Xiao, Y., Kassiou, M. (2012).
Consequences of linker length alteration of the
alpha7 nicotinic acetylcholine receptor (nAChR)
agonist, SEN12333. Bioorganic and Medicinal
Chemistry Letters: the tetrahedron journal for
research at the interface of chemistry and
biology, 22(7), 2380-2384. <a
href="http://dx.doi.org/10.1016/j.bmcl.2012.02.0
52">[More Information]</a>
Leaver, K., Reynolds, A., Bodard, S., Guilloteau,
D., Chalon, S., Kassiou, M. (2012). Effects of
Translocator Protein (18 kDa) Ligands on
Microglial Activation and Neuronal Death in the
Quinolinic-Acid-Injected Rat Striatum. ACS
Chemical Neuroscience, 3(2), 114-119. <a
href="http://dx.doi.org/10.1021/cn200099e">[M
ore Information]</a>
Scarf, A., Luus, C., Da Pozzo, E., Selleri, S.,
Guarino, C., Martini, C., Ittner, L., Kassiou, M.
(2012). Evidence for complex binding profiles
and species differences at the translocator protein
(TSPO) (18 kDa). Current Molecular Medicine,
12(4), 488-493. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=22348617">[More Information]</a>
Moussa, I., Banister, S., Manoli, M.,
Doddareddy, M., Cui, J., Mach, R., Kassiou, M.
(2012). Exploration of ring size in a series of
cyclic vicinal diamines with sigma(1)
receptor-affinity. Bioorganic & Medicinal
Chemistry Letters, 22(17), 5493-5497. <a
href="http://dx.doi.org/10.1016/j.bmcl.2012.07.0
26">[More Information]</a>
Gilmore, A., Heblinski, M., Reynolds, A.,
Kassiou, M., Connor, M. (2012). Inhibition of
human recombinant T-type calcium channels by
N-arachidonoyl 5-HT. British Journal of
Pharmacology, 167(5), 1076-1088. <a
href="http://dx.doi.org/10.1111/j.1476-5381.201
2.02047.x">[More Information]</a>
Arlicot, N., Vercouillie, J., Ribeiro, M., Tauber,
C., Venel, Y., Baulieu, J., Maia, S., Corcia, P.,
Stabin, M., Reynolds, A., Kassiou, M., et al
(2012). Initial evaluation in healthy humans of
[18F]DPA-714, a potential PET biomarker for
neuroinflammation. Nuclear Medicine and
Biology, 39(4), 570-578. <a
href="http://dx.doi.org/10.1016/j.nucmedbio.201
1.10.012">[More Information]</a>
Scarf, A., Aumann, K., Kassiou, M. (2012). Is
there any correlation between binding and
functional effects at the translocator protein
(TSPO) (18 kDa)? Current Molecular Medicine,
12(4), 387-397. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=22348609">[More Information]</a>
Corcia, P., Tauber, C., Vercoullie, J., Arlicot, N.,
Prunier, C., Praline, J., Nicolas, G., Venel, Y.,
Hommet, C., Baulieu, J., Kassiou, M., et al
(2012). Molecular imaging of microglial
activation in amyotrophic lateral sclerosis. PloS
One, 7(12), 1-7. <a
href="http://dx.doi.org/10.1371/journal.pone.005
2941">[More Information]</a>
Endres, C., Coughlin, J., Gage, K., Watkins, C.,
Kassiou, M., Pomper, M. (2012). Radiation
dosimetry and biodistribution of the TSPO ligand
(11)C-DPA-713 in humans. The Journal of
Nuclear Medicine, 53(2), 330-335. <a
href="http://dx.doi.org/10.2967/jnumed.111.094
565">[More Information]</a>
Gosling, J., Baker, S., Haynes, J., Kassiou, M.,
Pouton, C., Warfe, L., White, P., Scammells, P.
(2012). Synthesis and Biological Evaluation of
Adenosines with
Heterobicyclic and Polycyclic N6-Substituents as
Adenosine A1 Receptor Agonists.
ChemMedChem: chemistry enabling drug
discovery, 7(7), 1191-1201. <a
Publications for Michael Kassiou
href="http://dx.doi.org/10.1002/cmdc.201200208
">[More Information]</a>
Fulham, M., Kassiou, M., Greguric, I., Thomson,
S., Eberl, S., Tiam, P., Mattner, F., Henderson,
D., Fulton, R., Katsifis, A., et al (2012).
Synthesis and in vivo evaluation of arylalkyl
4-benzyl piperidines as radioligands for sigma
receptors. 16th International Symposium on
Radiopharmaceutical Chemistry, United
Kingdom: Wiley.
Behavior, and Immunity, 25(6), 1113-1122. <a
href="http://dx.doi.org/10.1016/j.bbi.2011.02.00
8">[More Information]</a>
Dolle, F., Le Helleix, S., Schollhorn-Peyronneau,
M., Saba, W., Banister, S., Tournier, N., Valette,
H., Kassiou, M. (2011). Carbon-11-labelling of a
novel, trishomocubane-derived, high affinity and
selectivity DAT ligand. Journal of Labelled
Compounds and Radiopharmaceuticals, 54(1),
S276-S276.
Hicks, C., Jorgensen, W., Brown, C., Fardell, J.,
Koehbach, J., Gruber, C., Kassiou, M., Hunt, G.,
McGregor, I. (2012). The Nonpeptide Oxytocin
Receptor Agonist WAY 267,464:
Receptor-Binding Profile, Prosocial Effects and
Distribution of c-Fos Expression in Adolescent
Rats. Journal of Neuroendocrinology, 24(7),
1012-1029. <a
href="http://dx.doi.org/10.1111/j.1365-2826.201
2.02311.x">[More Information]</a>
Moussa, I., Banister, S., Akladios, F., Chua, S.,
Kassiou, M. (2011). Effects of linker elongation
in a series of
N-(2-benzofuranylmethyl)-N'-(methoxyphenylal
kyl)piperazine sigma(1) receptor ligands.
Bioorganic and Medicinal Chemistry Letters: the
tetrahedron journal for research at the interface
of chemistry and biology, 21(19), 5707-5710. <a
href="http://dx.doi.org/10.1016/j.bmcl.2011.08.0
29">[More Information]</a>
Banister, S., Kassiou, M. (2012). The
Therapeutic Potential of Sigma (sigma)
Receptors for the Treatment of Central Nervous
System Diseases: Evaluation of the Evidence.
Current Pharmaceutical Design, 18(7), 884-901.
<a
href="http://dx.doi.org/10.2174/1381612127994
36539">[More Information]</a>
Banister, S., Moussa, I., Jorgensen, W., Chua, S.,
Kassiou, M. (2011). Molecular hybridization of
4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,1
1)]dodecane-3-ol with sigma (σ) receptor ligands
modulates off-target activity and subtype
selectivity. Bioorganic and Medicinal Chemistry
Letters: the tetrahedron journal for research at
the interface of chemistry and biology, 21(12),
3622-3626. <a
href="http://dx.doi.org/10.1016/j.bmcl.2011.04.0
98">[More Information]</a>
2011
Dolle, F., Kuhnast, B., Damont, A., van Camp,
N., Kassiou, M., Tavitian, B., Boisgard, R.
(2011). [18F]DPA-716 as a candidate for
imaging the TSPO 18 kDa with PET:
Radiosynthesis and comparative evaluation
([11C]DPA-713/[18F]DPA-714) in a rat model
of neuroinflammation. Journal of Labelled
Compounds and Radiopharmaceuticals, 54(1),
S275-S275.
Vercouillie, J., Ribeiro, M., Tauber, C., Venel,
Y., Baulieu, J., Maia, S., Reynolds, A., Kassiou,
M., Guilloteau, D., Corcia, P. (2011).
Biodistribution of the TSPO radioligand
(18)F-DPA-714 in healthy volunteers. Journal of
Labelled Compounds and Radiopharmaceuticals,
54(1), S255-S255.
Issa, F., Kassiou, M., Rendina, L. (2011). Boron
in drug discovery: Carboranes as unique
pharmacophores in biologically active
compounds. Chemical Reviews, 111(9),
5701-5722. <a
href="http://dx.doi.org/10.1021/cr2000866">[M
ore Information]</a>
Drake, C., Boutin, H., Jones, M., Denes, A.,
McColl, B., Selvarajah, J., Hulme, S., Georgiou,
R., Hinz, R., Gerhard, A., Kassiou, M., et al
(2011). Brain inflammation is induced by
co-morbidities and risk factors for stroke. Brain,
Banister, S., Yoo, D., Chua, S., Cui, J., Mach, R.,
Kassiou, M. (2011).
N-arylalkyl-2-azaadamantanes as cage-expanded
polycarbocyclic sigma (sigma) receptor ligands.
Bioorganic and Medicinal Chemistry Letters: the
tetrahedron journal for research at the interface
of chemistry and biology, 21(18), 5289-5292. <a
href="http://dx.doi.org/10.1016/j.bmcl.2011.07.0
28">[More Information]</a>
Ribeiro, M., Vercouillie, J., Tauber, C., Venel,
Y., Baulieu, J., Maia, S., Reynolds, A., Kassiou,
M., Guilloteau, D., Corcia, P. (2011). P-167 The
potential interest of the PET radioligand
(18)F-DPA-714 in neuroinflammation. Journal
of Labelled Compounds and
Radiopharmaceuticals, 54(1), S256-S256.
Martin, A., Boisgard, R., Kassiou, M., Dolle, F.,
Tavitian, B. (2011). Reduced PBR/TSPO
Expression After Minocycline Treatment in a Rat
Model of Focal Cerebral Ischemia: A PET
Study Using [(18)F]DPA-714. Molecular
Imaging and Biology, 13(1), 10-15. <a
href="http://dx.doi.org/10.1007/s11307-010-032
4-y">[More Information]</a>
Boucher, A., Arnold, J., Hunt, G., Spiro, A.,
Spencer, J., Brown, C., McGregor, I., Bennett,
M., Kassiou, M. (2011). Resilience and Reduced
Publications for Michael Kassiou
C-FOS Expression in P2X7 Receptor Knockout
Mice Exposed to Repeated Forced Swim Test.
Neuroscience, 189, 170-177. <a
href="http://dx.doi.org/10.1016/j.neuroscience.2
011.05.049">[More Information]</a>
Crossley, E., Issa, F., Scarf, A., Kassiou, M.,
Rendina, L. (2011). Synthesis and cellular uptake
of boron-rich pyrazolopyrimidines: exploitation
of the translocator protein for the efficient
delivery of boron into human glioma cells.
Chemical Communications, 47(44),
12179-12181. <a
href="http://dx.doi.org/10.1039/c1cc14587h">[
More Information]</a>
Moussa, I., Banister, S., Giboureau, N., Meikle,
S., Kassiou, M. (2011). Synthesis and in vivo
evaluation of
[18F]N-(2-benzofuranylmethyl)-N'-[4-(2-fluoroe
thoxy)benzyl]piperazine, a novel σ1 receptor
PET imaging agent. Bioorganic and Medicinal
Chemistry Letters: the tetrahedron journal for
research at the interface of chemistry and
biology, 21(22), 6820-6823. <a
href="http://dx.doi.org/10.1016/j.bmcl.2011.09.0
28">[More Information]</a>
Damont, A., Boisgard, R., Kuhnast, B., Lemee,
F., Raggiri, G., Scarf, A., Da Pozzo, E., Selleri,
S., Martini, C., Tavitian, B., Kassiou, M., et al
(2011). Synthesis of 6-[(18)F]fluoro-PBR28, a
novel radiotracer for imaging the TSPO 18 kDa
with PET. Bioorganic and Medicinal Chemistry
Letters: the tetrahedron journal for research at
the interface of chemistry and biology, 21(16),
4819-4822. <a
href="http://dx.doi.org/10.1016/j.bmcl.2011.06.0
48">[More Information]</a>
Scarf, A., Kassiou, M. (2011). The translocator
protein. The Journal of Nuclear Medicine, 52(5),
677-680. <a
href="http://dx.doi.org/10.2967/jnumed.110.086
629">[More Information]</a>
Banister, S., Moussa, I., Beinat, C., Reynolds,
A., Schiavini, P., Jorgensen, W., Kassiou, M.
(2011). Trishomocubane as a Scaffold for the
Development of Selective Dopamine Transporter
(DAT) Ligands. Bioorganic and Medicinal
Chemistry Letters: the tetrahedron journal for
research at the interface of chemistry and
biology, 21(1), 38-41. <a
href="http://dx.doi.org/10.1016/j.bmcl.2010.11.0
75">[More Information]</a>
2010
Banister, S., Clegg, J., Hanani, R., Kassiou, M.
(2010).
11-[2-(3-fluorophenyl)ethyl](methyl)-aminopent
acyclo[5.4.0.0(2,6).0(3,10).0(5,9)]-undecan-8-on
e. Acta Crystallographica. Section E: Structure
Reports Online, 66(10), o2693-o2693.
Kassiou, M., James, M. (2010).
2-Arylpyrazolo[L,5-a]Pyrimidin-3-yl Acetamide
Deriv As Ligands For Translocator Protein.
Patent No. 2008/10473. South Africa.
Naidoo (Naidoo-Variawa), S., Lehnert, W.,
Kassiou, M., Banati, R., Meikle, S. (2010).
Attenuation correction for the large non-human
primate brain imaging using microPET. Physics
in Medicine and Biology, 55(8), 2351-2363. <a
href="http://dx.doi.org/10.1088/0031-9155/55/8/
015">[More Information]</a>
Morrison, D., Issa, F., Bhadbhade, M., Groebler,
L., Witting, P., Kassiou, M., Rutledge, P.,
Rendina, L. (2010). Boronated phosphonium
salts containing arylboronic acid,
closo-carborane, or nido-carborane: synthesis,
X-ray diffraction, in vitro cytotoxicity, and
cellular uptake. Journal of Biological Inorganic
Chemistry, 15(8), 1305-1318. <a
href="http://dx.doi.org/10.1007/s00775-010-069
0-6">[More Information]</a>
Moussa, I., Banister, S., Beinat, C., Giboureau,
N., Reynolds, A., Kassiou, M. (2010). Design,
synthesis, and structure-affinity relationships of
regioisomeric N-benzyl alkyl ether piperazine
derivatives as sigma-1 receptor ligands. Journal
of Medicinal Chemistry, 53(16), 6228-6239. <a
href="http://dx.doi.org/10.1021/jm100639f">[M
ore Information]</a>
Giboureau, N., Aumann, K., Beinat, C., Kassiou,
M. (2010). Development of vesicular
acetylcholine transporter ligands: Molecular
probes for Alzheimer's disease. Current
Bioactive Compounds, 6(3), 129-155. <a
href="http://dx.doi.org/10.2174/1573407107932
37353">[More Information]</a>
Abraham, M., Boisgard, R., Theze, B., Van
Camp, N., Kuhnast, B., Damont, A., Kassiou,
M., Dolle, F., Tavitian, B. (2010). Evaluation of
the PBR/TSPO radioloigand [18F]DPA-714 in a
rat model of focal cerebral ischemia. Journal of
Cerebral Blood Flow and Metabolism, 30(1),
230-241. <a
href="http://dx.doi.org/10.1038/jcbfm.2009.205"
>[More Information]</a>
Banister, S., Roeda, D., Dolle, F., Kassiou, M.
(2010). Fluorine-18 chemistry for PET: A
concise introduction. Current
Radiopharmaceuticals, 3(2), 68-80. <a
href="http://dx.doi.org/10.2174/1874471011003
020068">[More Information]</a>
Beinat, C., Banister, S., Moussa, I., Reynolds,
A., McErlean, C., Kassiou, M. (2010). Insights
into structure-activity relationships and CNS
therapeutic applications of NR2B selective
antagonists. Current Medicinal Chemistry,
17(34), 4166-4190. <a
href="http://dx.doi.org/10.2174/0929867107933
Publications for Michael Kassiou
48572">[More Information]</a>
Fulton, R., Meikle, S., Kyme, A., Zhou, W.,
Popovic, K., Kassiou, M., Akhtar, M. (2010).
Motion-corrected microPET brain imaging of
conscious rats. 2009 World Molecular Imaging
Conference, USB drive/online: Online.
Banister, S., Moussa, I., Jordan, M., Coster, M.,
Kassiou, M. (2010). Oxo-bridged isomers of
aza-trishomocubane sigma (o) receptor
ligands: Synthesis, in vitro binding, and
molecular modeling. Bioorganic and Medicinal
Chemistry Letters: the tetrahedron journal for
research at the interface of chemistry and
biology, 20(1), 145-148. <a
href="http://dx.doi.org/10.1016/j.bmcl.2009.11.0
19">[More Information]</a>
Gunosewoyo, H., Kassiou, M. (2010). P2X
purinergic receptor ligands: Recently patented
compounds. Expert Opinion on Therapeutic
Patents, 20(5), 625-646. <a
href="http://dx.doi.org/10.1517/1354377100370
2424">[More Information]</a>
Giboureau, N., Mat Som, I., Boucher, A.,
Guilloteau, D., Kassiou, M. (2010). PET
Radioligands for the Vesicular Acetylcholine
Transporter (VAChT). Current Topics in
Medicinal Chemistry, 10(15), 1569-1583. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=20583990">[More Information]</a>
Reynolds, A., Hanani, R., Hibbs, D., Damont,
A., Da Pozzo, E., Selleri, S., Dolle, F., Martini,
C., Kassiou, M. (2010).
Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl
alkyl ether derivatives as potent ligands for the
18 kDa translocator protein (TSPO). Bioorganic
and Medicinal Chemistry Letters: the
tetrahedron journal for research at the interface
of chemistry and biology, 20(19), 5799-5802. <a
href="http://dx.doi.org/10.1016/j.bmcl.2010.07.1
35">[More Information]</a>
Luus, C., Hanani, R., Reynolds, A., Kassiou, M.
(2010). The development of PET radioligands
for imaging the translocator protein (18 kDa):
What have we learned? Journal of Labelled
Compounds and Radiopharmaceuticals, 53(7),
501-510. <a
href="http://dx.doi.org/10.1002/jlcr.1752">[Mor
e Information]</a>
2009
Valette, H., Xiao, Y., Schollhorn-Peyronneau,
M., Damont, A., Kosikowski, A., Wei, Z.,
Kassiou, M., Kellar, K., Dolle, F., Bottlaender,
M. (2009). 18F-ZW-104: A New Radioligand for
Imaging Neuronal Nicotinic Acetylcholine
Receptors-In Vitro Binding Properties and PET
Studies in Baboons. The Journal of Nuclear
Medicine, 50(8), 1349-1355. <a
href="http://dx.doi.org/10.2967/jnumed.108.061
374">[More Information]</a>
Doorduin, J., Klein, H., Dierckx, R., James, M.,
Kassiou, M., De Vries, E. (2009).
[11C]-DPA-713 and [18F]-DPA-714 as new
PET tracers for TSPO: A comparison with
[11C]-(R)-PK11195 in a rat model of herpes
encephalitis. Molecular Imaging and Biology,
11(6), 386-398. <a
href="http://dx.doi.org/10.1007/s11307-009-021
1-6">[More Information]</a>
Damont, A., van Camp, N., Kuhnast, B., Hinnen,
F., Boisgard, R., Chauveau, F., Boutin, H.,
Probst, K., Clark, J., Katsifis, A., Kassiou, M.
(2009). [18F]DPA-714, [18F]PBR111 and
[18F]FEDAA1106 as potent PBR pet-imaging
candidates: Radiosynthesis and comparative
studies. Journal of Labelled Compounds and
Radiopharmaceuticals, 52(S1), S122-S122.
Banister, S., Coster, M., Kassiou, M. (2009). A
versatile polycyclic scaffold for the discovery of
selective sigma (sigma) receptor ligands. 7th
AFMC International Medicinal Chemistry
Symposium, Cairns.
Truong, L., Allbutt, H., Coster, M., Kassiou, M.,
Henderson, J. (2009). Behavioural effects of a
selective NMDA NR1A/2B receptor antagonist
in rats with unilateral 6-OHDA+ parafascicular
lesions. Brain Research Bulletin, 78(2-3), 91-96.
<a
href="http://dx.doi.org/10.1016/j.brainresbull.20
08.10.004">[More Information]</a>
Kassiou, M., Banati, R., Holsinger, D., Meikle,
S. (2009). Challenges in molecular imaging of
Parkinson's disease: A brief overview. Brain
Research Bulletin, 78(2-3), 105-108. <a
href="http://dx.doi.org/10.1016/j.brainresbull.20
08.08.006">[More Information]</a>
Chauveau, F., Van Camp, N., Dolle, F., Kuhnast,
B., Hinnen, F., Damont, A., Boutin, H., James,
M., Kassiou, M., Tavitian, B. (2009).
Comparative evaluation of the translocator
protein radioligands (11)C-DPA-713,
(18)F-DPA-714, and (11)C-PK11195 in a rat
model of acute neuroinflammation. The Journal
of Nuclear Medicine, 50(3), 468-476. <a
href="http://dx.doi.org/10.2967/jnumed.108.058
669">[More Information]</a>
Kassiou, M. (2009). Discovery of new
therapeutic immunomodulator drugs as a
pathway for treating brain disease. Plant
Nutraceuticals and Bioactive Molecules: A
Growth Opportunity for the Pharmaceutical
Industry in Australia and India, N/A: N/A.
Warraich, S., Allbutt, H., Billing, R., Radford, J.,
Coster, M., Kassiou, M., Henderson, J. (2009).
Publications for Michael Kassiou
Evaluation of behavioural effects of a selective
NMDA NR1A/2B receptor antagonist in the
unilateral 6-OHDA lesion rat model. Brain
Research Bulletin, 78(2-3), 85-90. <a
href="http://dx.doi.org/10.1016/j.brainresbull.20
08.08.023">[More Information]</a>
Edington, A., McKinzie, A., Reynolds, A.,
Kassiou, M., Ryan, R., Vandenberg, R. (2009).
Extracellular loops 2 and 4 of GLYT2 are
required for N-arachidonylglycine inhibition of
glycine transport. Journal of Biological
Chemistry, 284(52), 36424-36430. <a
href="http://dx.doi.org/10.1074/jbc.M109.01750
9">[More Information]</a>
Kassiou, M. (2009). Imaging immune response
in the CNS - Applications for therapeutic
development. 7th AFMC International Medicinal
Chemistry Symposium, Cairns.
Endres, C., Pomper, M., James, M., Uzuner, O.,
Hammoud, D., Watkins, C., Reynolds, A.,
Hilton, J., Dannals, R., Kassiou, M. (2009).
Initial evaluation of 11C-DPA-713, a novel
TSPO PET ligand, in humans. The Journal of
Nuclear Medicine, 50(8), 1276-1282. <a
href="http://dx.doi.org/10.2967/jnumed.109.062
265">[More Information]</a>
Leaver, K., Allbutt, H., Creber, N., Kassiou, M.,
Henderson, J. (2009). Oral pre-treatment with
epigallocatechin gallate in 6-OHDA lesioned rats
produces subtle symptomatic relief but not
neuroprotection. Brain Research Bulletin, 80(6),
397-402. <a
href="http://dx.doi.org/10.1016/j.brainresbull.20
09.08.013">[More Information]</a>
Kassiou, M., James, M., Luus, C. (2009).
Patent No. WO2009079683 (A1).
Gunosewoyo, H., Coster, M., Bennett, M.,
Kassiou, M. (2009). Purinergic P2X(7) receptor
antagonists:Chemistry and fundamentals of
biological screening. Bioorganic and Medicinal
Chemistry, 17(14), 4861-4865. <a
href="http://dx.doi.org/10.1016/j.bmc.2009.05.0
83">[More Information]</a>
Dolle, F., Luus, C., Reynolds, A., Kassiou, M.
(2009). Radiolabelled molecules for imaging the
translocator protein (18 kDa) using positron
emission tomography. Current Medicinal
Chemistry, 16(22), 2899-2923. <a
href="http://dx.doi.org/10.2174/0929867097888
03150">[More Information]</a>
Reynolds, A., Kassiou, M. (2009). Recent
advances in the Mitsunobu reaction:
Modifications and applications to biologically
active molecules. Current Organic Chemistry,
13(16), 1610-1632. <a
href="http://dx.doi.org/10.2174/1385272097895
78144">[More Information]</a>
Moussa, I., Coster, M., Kassiou, M. (2009).
Synthesis and pharmacological evaluation of
novel sigma receptor ligands. 7th AFMC
International Medicinal Chemistry Symposium,
Cairns.
Scarf, A., Ittner, L., Kassiou, M. (2009). The
translocator protein (18 kDa): Central nervous
system disease and drug design. Journal of
Medicinal Chemistry, 52(3), 581-592. <a
href="http://dx.doi.org/10.1021/jm8011678">[M
ore Information]</a>
Ioppolo, J., Kassiou, M., Rendina, L. (2009).
Water-soluble phosphonium salts containing
1,12-dicarba-closo-dodecaborane(12).
Tetrahedron Letters, 50(47), 6457-6461. <a
href="http://dx.doi.org/10.1016/j.tetlet.2009.08.1
12">[More Information]</a>
Dolle, F., Damont, A., Valette, H., Hinnen, F.,
Kuhnast, B., Saba, W., Schollhorn-Peyronneau,
M., Kozikowski, A., Bottlaender, M., Kassiou,
M. (2009). ZW-102 and ZW-104, two novel
fluorine-18 labelled radioligands for imaging
nicotinic acetylcholine receptors with PET.
Journal of Labelled Compounds and
Radiopharmaceuticals, 52(S1), S364.
2008
van Dijk, A., Johnston, C., Allbutt, H., Kassiou,
M., Henderson, J. (2008). Behavioural effects of
trishomocubanes in rats with unilateral
6-hydroxydopamine lesions. Behavioural Brain
Research, 190(1), 14-21. <a
href="http://dx.doi.org/10.1016/j.bbr.2008.02.03
4">[More Information]</a>
Gunosewoyo, H., Liu, G., Bennett, M., Coster,
M., Kassiou, M. (2008). Cubyl amides: Novel
P2X(7) receptor antagonists. Bioorganic and
Medicinal Chemistry Letters: the tetrahedron
journal for research at the interface of chemistry
and biology, 18(13), 3720-3723. <a
href="http://dx.doi.org/10.1016/j.bmcl.2008.05.0
62">[More Information]</a>
Besret, L., Dolle, F., Herard, A., Guillermier, M.,
Demphel, S., Hinnen, F., Coulon, C., Ottaviani,
M., Bottlaender, M., Hantraye, P., Kassiou, M.
(2008). Dopamine D1 Receptor Imaging in the
Rodent and Primate Brain Using the Isoquinoline
(+)-[(11)C]A-69024 and Positron Emission
Tomography. Journal of Pharmaceutical
Sciences, 97(7), 2811-2819. <a
href="http://dx.doi.org/10.1002/jps.21168">[Mor
e Information]</a>
James, M., Fulton, R., Vercoullie, J., Henderson,
D., Garreau, L., Chalon, S., Dolle, F., Selleri, S.,
Guilloteau, D., Kassiou, M. (2008). DPA-714, a
New Translocator Protein-Specific Ligand:
Synthesis, Radiofluorination, and Pharmacologic
Characterization. The Journal of Nuclear
Publications for Michael Kassiou
Medicine, 49(5), 814-822. <a
href="http://dx.doi.org/10.2967/jnumed.107.046
151">[More Information]</a>
Leaver, K., Allbutt, H., Creber, N., Kassiou, M.,
Henderson, J. (2008). Neuroprotective effects of
a selective N-methyl-D-aspartate NR2B receptor
antagonist in the 6-hydroxydopamine rat model
of Parkinson's disease. Clinical and
Experimental Pharmacology and Physiology,
35(11), 1388-1394. <a
href="http://dx.doi.org/10.1111/j.1440-1681.200
8.05046.x">[More Information]</a>
Henderson, J., Lanciego, J., Smith, Y., Gundlach,
A., Kassiou, M. (2008). Proceedings of the 2007
International Brain Research Organisation
Satellite Meeting "Movement Disorders: Focus
on the Thalamus and Basal Ganglia" held in
Sydney, Australia, 10-11 July, 2007. Brain
Research Bulletin, 78(2-3), 53-54. <a
href="http://dx.doi.org/10.1016/j.brainresbull.20
08.09.015">[More Information]</a>
Fulton, R., Kyme, A., Zhou, V., Leaver, K.,
Kassiou, M., Lehnert, W., Meikle, S. (2008).
Progress towards microPET imaging of small,
awake laboratory animals. 2008 World
Molecular Imaging Congress, Europe: World
Molecular Imaging Congress.
Guenther, K., Hambley, T., Kassiou, M. (2008).
Radiolabelled probes for imaging multidrug
resistance using single photon emission
tomography (SPECT) and positron emission
tomography (PET). In Nicola Antonio Colabufo
(Eds.), Multidrug Resistance: Biological and
Pharmaceutical Advances in Antitumour
Treatment, (pp. 291-320). India: Research
Signpost.
Damont, A., Hinnen, F., Kuhnast, B.,
Schollhorn-Peyronneau, M., James, M., Luus, C.,
Tavitian, B., Kassiou, M., Dolle, F. (2008).
Radiosynthesis of [(18)F]DPA-714, a selective
radioligand for imaging the translocator protein
(18 kDa) PET. Journal of Labelled Compounds
and Radiopharmaceuticals, 51(7-8), 286-292. <a
href="http://dx.doi.org/10.1002/jlcr.1523">[Mor
e Information]</a>
Dolle, F., Langle, S., Roger, G., Fulton, R.,
Lagnel, B., Henderson, D., Hinnen, F., Paine, T.,
Coster, M., Valette, H., Kassiou, M., et al (2008).
Synthesis and In-Vivo Evaluation of
[(11)C]p-PVP-MEMA as a PET Radioligand for
Imaging Nicotinic Receptors. Australian Journal
of Chemistry, 61(6), 438-445. <a
href="http://dx.doi.org/10.1071/CH08083">[Mor
e Information]</a>
2007
Doorduin, J., Klein, H., James, M., Kassiou, M.,
Dierckx, R., Vries, E. (2007). (18F)DPA-714 as
a novel PET tracer for PBR: A comparison with
(11C)PK11195 in a rat model of HSV
encephalitis. 17th International Symposium on
Radiopharmaceutical Sciences. John Wiley &
Sons.
Banister, S., Clegg, J., Coster, M., Jolliffe, K.,
Kassiou, M. (2007).
(1R,2S,3R,6S,7R,8S)-Tricyclo[6.2.1.02,7]-undec
a-4,9-diene-3,6-diol. Acta Crystallographica.
Section E: Structure Reports Online, E63,
o92-o93.
Emond, P., Mavel, S., Zea-Ponce, Y., Kassiou,
M., Garreau, L., Bodard, S., Drossard, M.,
Chalon, S., Guilloteau, D. (2007).
(E)-[125I]-5-AOIBV: a SPECT radioligand for
the vesicular acetylcholine transporter. Nuclear
Medicine and Biology, 34(8), 967-971.
Boutin, H., Chauveau, F., Thominiaux, C.,
Gregoire, M., James, M., Trebossen, R.,
Hantraye, P., Dolle, F., Tavitian, B., Kassiou, M.
(2007). 11C-DPA-713: A novel peripheral
benzodiazepine receptor PET ligand for in vivo
imaging of neuroinflammation. The Journal of
Nuclear Medicine, 48(4), 573-581.
Kozikowski, A., Chellappan, S., Henderson, D.,
Fulton, R., Giboureau, N., Xiao, Y., Wei, Z.,
Guilloteau, D., Emond, P., Dolle, F., Kassiou,
M., et al (2007). Acetylenic pyridines for use in
PET imaging of nicotinic receptors.
ChemMedChem: chemistry enabling drug
discovery, 2, 54-57. <a
href="http://dx.doi.org/10.1002/cmdc.200600220
">[More Information]</a>
Quinlivan, M., Chalon, S., Vergote, J.,
Henderson, J., Katsifis, A., Kassiou, M.,
Guilloteau, D. (2007). Decreased vesicular
acetylcholine transporter and alpha-4beta-2
nicotinic receptor density in the rat brain
following 192 IgG-saporin immunolesioning.
Neuroscience Letters, 415, 97-101. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17339079">[More Information]</a>
James, M., Fulton, R., Vercouille, J., Henderson,
D., Garreau, L., Eberl, S., Chalon, S., Selleri, S.,
Dolle, F., Guilloteau, D., Kassiou, M. (2007).
DPA-714 A new translocator protein (18kDa)
ligand: Synthesis, radiofluorination and
pharmacological characterisation. 17th
International Symposium on
Radiopharmaceutical Sciences. John Wiley &
Sons.
Mavel, S., Zea-Ponce, Y., Garreau, L., Chalon,
S., Kassiou, M., Guilloteau, D., Emond, P.
(2007). E-((R,R) and (S,S))-5-(125I)-AOIBV:
Potential SPECT tracers in vivo studies of the
vesicular AcetylCholine Transporter (VACht).
17th International Symposium on
Publications for Michael Kassiou
Radiopharmaceutical Sciences. John Wiley &
Sons.
Giboureau, N., Emond, P., Fulton, R.,
Henderson, D., Chalon, S., Garreau, L., Roselt,
P., Eberl, S., Mavel, S., Bodard, S., Fulham, M.,
Kassiou, M., et al (2007). Ex vivo and in vivo
evaluation of (2R,3R)-5-[18F]-fluoroethoxy- and
fluoropropoxy-benzovesamicol, as PET
radioligands for the vesicular acetylcholine
transporter. Synapse (New York), 61(12),
962-670. <a
href="http://dx.doi.org/10.1002/syn.20450">[Mo
re Information]</a>
Naidoo (Naidoo-Variawa), S., Hey Cunningham,
A., Lehnert, W., Kench, P., Kassiou, M., Banati,
R., Meikle, S. (2007). High-resolution imaging
of the large non-human primate brain using
microPET: a feasibility study. Physics in
Medicine and Biology, 52(22), 6627-6638. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17975287">[More Information]</a>
Collier, T., Waterhouse, R., Kassiou, M. (2007).
Imaging sigma receptors: Applications in drug
development. Current Pharmaceutical Design,
13, 51-72. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17266588">[More Information]</a>
Kassiou, M. (2007). Molecular imaging in drug
development (EDITORIAL). Current
Pharmaceutical Design, 13(1), 1-1.
Gunosewoyo, H., Coster, M., Kassiou, M.
(2007). Molecular probes for P2X7 receptor
studies. Current Medicinal Chemistry, 14(14),
1505-1523. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17584060">[More Information]</a>
Cagnin, A., Kassiou, M., Meikle, S., Banati, R.
(2007). Positron emission tomography imaging
of neuroinflammation. Neurotherapeutics, 4(3),
443-452. <a
href="http://dx.doi.org/10.1016/j.nurt.2007.04.00
6">[More Information]</a>
Kassiou, M., Chellappan, S., Henderson, D.,
Fulton, R., Giboureau, N., Xiao, Y., Wei, Z.,
Guilloteau, D., Emond, P., Dolle, F., et al (2007).
Radiosynthesis and preliminary evaluation of
ZW-90 and ZW-110, two novel acetylenic
pyridines for imaging nicotonic receptors. 17th
International Symposium on
Radiopharmaceutical Sciences. John Wiley &
Sons.
Giboureau, N., Chalon, S., Garreau, L., Kassiou,
M., Emond, P., Guilloteau, D. (2007). Rat
distribution of (18F)-Fuoropropoxy- and
(18F)-Fluoroethoxybenzovesamicol, as PET
radioligands for the vesicular acetylcholine
transporter (VACht). 17th International
Symposium on Radiopharmaceutical Sciences.
John Wiley & Sons.
Creelman, A., Thominiaux, C., Chauveau, F.,
Fulton, R., Kuhnast, B., Henderson, D., Boutin,
H., Selleri, S., McGregor, I., Hantraye, P.,
Kassiou, M., et al (2007). Synthesis and
evaluation of the translocator protein (18kDa)
(TSPO) ligand (11C)DPA0715 in rat and
non-human primate. 17th International
Symposium on Radiopharmaceutical Sciences.
John Wiley & Sons.
Langley, S., Roger, G., Fulton, R., Lagnel, B.,
Henderson, D., Hinnen, F., Bottlaender, M.,
Dolle, F., Kassiou, M. (2007). Synthesis and in
vivo evaluation of (11c)P-PVP-MEMA as a PET
radioligand for Imaging nicotonic receptors. 17th
International Symposium on
Radiopharmaceutical Sciences. John Wiley &
Sons.
Liu, X., Banister, S., Christie, M., Banati, R.,
Meikle, S., Coster, M., Kassiou, M. (2007).
Trishomocubanes: Novel sigma ligands
modulate cocaine-induced behavioural effects.
European Journal of Pharmacology, 555(1),
37-42.
2006
Truong, L., Allbutt, H., Kassiou, M., Henderson,
J. (2006). Developing a preclinical model of
Parkinson's disease: a study of behaviour in rats
with graded 6-OHDA lesions. Behavioural Brain
Research, 169(1), 1-9. <a
href="http://dx.doi.org/10.1016/j.bbr.2005.11.02
6">[More Information]</a>
James, M., Selleri, S., Kassiou, M. (2006).
Development of ligands for the peripheral
benzodiazepine receptor. Current Medicinal
Chemistry, 13(17), 1991-2001. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16842193">[More Information]</a>
Thominiaux, C., Dolle, F., James, M.,
Bramoulle, Y., Boutin, H., Besret, L., Gregoire,
M., Valette, H., Bottlaender, M., Tavitian, B.,
Kassiou, M., et al (2006). Improved synthesis of
the peripheral benzodiazepine receptor ligand
C-11 DPA-713 using C-11 methyl triflate.
Applied Radiation and Isotopes, 64(5), 570-573.
<a
href="http://dx.doi.org/10.1016/j.apradiso.2005.1
2.003">[More Information]</a>
Cagnin, A., Kassiou, M., Meikle, S., Banati, R.
(2006). In vivo evidence for microglial activation
in neurodegenerative dementia. Acta
Neurologica Scandinavica, 114(Supplement
Publications for Michael Kassiou
185), 107-114.
Thominiaux, C., de Bruin, B., Bramoulle, Y.,
Hinnen, F., Demphel, S., Valette, H.,
Bottlaender, M., Besret, L., Kassiou, M., Dolle,
F. (2006). Radiosynthesis of (E)-N-(2- C-11
methoxybenzyl)-3-phenyl-acrylamidine, a novel
subnanomolar NR2B subtype-selective NMDA
receptor antagonist. Applied Radiation and
Isotopes, 64(3), 348-354. <a
href="http://dx.doi.org/10.1016/j.apradiso.2005.0
8.005">[More Information]</a>
Assaad, T., Mavel, S., Parsons, S., Kruse, S.,
Galineau, L., Allouchi, H., Kassiou, M., Chalon,
S., Guilloteau, D., Emond, P. (2006). Synthesis
and in vitro evaluation of N-substituted
aza-trozamicol analogs as vesicular acetylcholine
transporter ligands. Bioorganic and Medicinal
Chemistry Letters: the tetrahedron journal for
research at the interface of chemistry and
biology, 16(10), 2654-2657. <a
href="http://dx.doi.org/10.1016/j.bmcl.2006.02.0
33">[More Information]</a>
Vercouillie, J., Mavel, S., Galineau, L., Ragusa,
T., Innis, R., Chalon, S., Kassiou, M., Dolle, F.,
Besnard, J., Guilloteau, D., et al (2006).
Synthesis and in vitro evaluation of novel
derivatives of diphenylsulfide as serotonin
transporter ligands. Bioorganic and Medicinal
Chemistry Letters: the tetrahedron journal for
research at the interface of chemistry and
biology, 16(5), 1297-1300. <a
href="http://dx.doi.org/10.1016/j.bmcl.2005.11.0
66">[More Information]</a>
Brain. Medicinal Chemistry, 1(1), 31-38. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16789883">[More Information]</a>
Kassiou, M., Meikle, S., Banati, R. (2005).
Ligands for peripheral benzodiazepine binding
sites in glial cells. Brain Research Reviews,
48(2), 207-210. <a
href="http://dx.doi.org/10.1016/j.brainresrev.200
4.12.010">[More Information]</a>
Kassiou, M., Bruin, B., Demphel, S., Besret, L.,
Hinnen, F., Dolle, F., Bramoulle, Y.,
Thominiaux, C., Bottlaender, M. (2005).
Radiosynthesis of
(E)-N-(2-[11C]methoxybenzyl)-3-phenyl-acryla
midine, a novel subnanomolar NR2B
subtype-selective NMDA receptor ligand. 16th
International Symposium on
Radiopharmaceutical Chemistry, United
Kingdom: Wiley.
Mohamed, A., Eberl, S., Fulham, M., Kassiou,
M., Zaman, A., Henderson, D., Beveridge, S.,
Constable, C., Lo, S. (2005). Sequential
123I-iododexetimide scans in temporal lobe
epilepsy: comparison with neuroimaging scans
(MR imaging and F-18-FDG PET imaging).
European Journal of Nuclear Medicine and
Molecular Imaging, 32(2), 180-185. <a
href="http://dx.doi.org/10.1007/s00259-004-165
4-2">[More Information]</a>
Issa, F., Kassiou, M., Chan, K., McLeod, M.
(2006). Synthesis and radiolabelling of
ipratropium and tiotropium for use as PET
ligands in the study of inhaled drug deposition.
Australian Journal of Chemistry, 59(1), 53-58.
Meikle, S., Kench, P., Kassiou, M., Banati, R.
(2005). Small animal SPECT and its place in the
matrix of molecular imaging technologies.
Physics in Medicine and Biology, 50(22),
R45-R61. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16264248">[More Information]</a>
Liu, X., Banister, S., Christie, M., Banati, R.,
Meikle, S., Coster, M., Kassiou, M. (2006).
Trishomocubanes: Novel Sigma ligands
modulate cocaine-induced behavioural effects.
European Journal of Pharmacology, 555(1),
37-42. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17113074">[More Information]</a>
Zea-Ponce, Y., Mavel, S., Assaad, T., Kruse, S.,
Parsons, S., Emond, P., Chalon, S., Giboureau,
N., Kassiou, M., Guilloteau, D. (2005). Synthesis
and in vitro evaluation of new benzovesamicol
analogues as potential imaging probes for the
vesicular acetylcholine transporter. Bioorganic
and Medicinal Chemistry, 13(3), 745-753. <a
href="http://dx.doi.org/10.1016/j.bmc.2004.10.0
43">[More Information]</a>
2005
Kassiou, M., Dannals, R., Liu, X., Wong, D.,
Ravert, H., Scheffel, U. (2005). Synthesis and in
vivo evaluation of a new PET radioligand for
studying sigma-2 receptors. Bioorganic and
Medicinal Chemistry, 13(11), 3623-3626. <a
href="http://dx.doi.org/10.1016/j.bmc.2005.03.0
39">[More Information]</a>
Kassiou, M. (2005). Capabilities of PET and
SPECT in pre-clinical and clinical research.
Current Pharmaceutical Design, 11(25),
3201-3201.
Liu, X., Mattner, F., Katsifis, A., Christie, M.,
Kassiou, M. (2005). Influence of
Trishomocubanes on Sigma Receptor Binding of
N-(1-Benzylpiperidin4-yl)-4-[123I]iodobenzamide In Vivo in the Rat
Fulham, M., Kassiou, M., Dolle, F., Thomson,
S., Henderson, D., James, M., Eberl, S., Fulton,
R., Allan, R. (2005). Synthesis and In Vivo
Evaluation of a Novel Peripheral Benzodiazepine
Publications for Michael Kassiou
Receptor PET Radioligand. 16th International
Symposium on Radiopharmaceutical Chemistry,
United Kingdom: Wiley.
James, M., Fulton, R., Henderson, D., Eberl, S.,
Meikle, S., Thomson, S., Allan, R., Dolle, F.,
Fulham, M., Kassiou, M. (2005). Synthesis and
in vivo evaluation of a novel peripheral
benzodiazepine receptor PET radioligand.
Bioorganic and Medicinal Chemistry. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16039131">[More Information]</a>
2004
Henderson, D., Eberl, S., Thomson, S., Smith,
A., Allan, R., Fulham, M., Loiacono, R.,
Kassiou, M. (2004). 3-Pyridyl Ethers As Spect
Radioligands For Imaging Nicotinic
Acetylcholine Receptors. Applied Radiation and
Isotopes, 60(5), 669-676. <a
href="http://dx.doi.org/10.1016/j.apradiso.2004.0
1.002">[More Information]</a>
Katsifis, A., Kassiou, M. (2004). Development
Of Radioligands For In Vivo Imaging Of
Gaba(A)-Benzodiazepine Receptors. Mini Reviews in Medicinal Chemistry, 4(8), 909-921.
Dolle, F., Valette, H., Demphel, S., Coulon, C.,
Ottaviani, M., Bottlaender, M., Kassiou, M.
(2004). Radiosynthesis And In Vivo Evaluation
Of [11C]Ro-547312: A Novel Nr1/2B Subtype
Selective Nmda Receptor Radioligand. Journal
of Labelled Compounds and
Radiopharmaceuticals, 47(13), 911-920. <a
href="http://dx.doi.org/10.1002/jlcr.877">[More
Information]</a>
Roger, G., Dolle, F., de Bruin, B., Liu, X.,
Besret, L., Bramoulle, Y., Coulon, C., Ottaviani,
M., Bottlaender, M., Valette, H., Kassiou, M.
(2004). Radiosynthesis And Pharmacological
Evaluation Of [11C]Emd-95885: A High
Affinity Ligand For Nr2B-Containing Nmda
Receptors. Bioorganic and Medicinal Chemistry,
12(12), 3229-3237. <a
href="http://dx.doi.org/10.1016/j.bmc.2004.03.0
65">[More Information]</a>
Roselt, P., Meikle, S., Kassiou, M. (2004). The
Role Of Positron Emission Tomography In The
Discovery And Development Of New Drugs; As
Studied In Laboratory Animals. European
Journal of Drug Metabolism and
Pharmacokinetics, 29(1), 1-6.
2003
Kassiou, M., Katsifis, A. (2003). PET
radiochemistry in drug development and
evaluation. Chemistry in Australia, 70(5), 10-12.
Katsifis, A., Mardon, K., Mattner, F., Loc'h, C.,
McPhee, M., Dikic, B., Kassiou, M., Ridley, D.
(2003). Pharmacological evaluation of
(S)-8-[123I]iodobretazenil: a radioligand for in
vivo studies of central benzodiazepine receptors.
Nuclear Medicine and Biology, 30(2), 191-198.
Feng, D., Kassiou, M., Fulham, M., Wong, K.,
Elberl, S. (2003). Quantification of
5-[123I]iodo-A-85380 in nonhuman primates
using spect: parameter identifiability and
stabilitty. Modelling and Control in Biomedical
Systems 2003 (Including Biological Systems),
UK: Pergamon.
Quinlivan, M., Mattner, F., Papazian, V., Zhou,
J., Katsifis, A., Emond, P., Chalon, S.,
Kozikowski, A., Guilloteau, D., Kassiou, M.
(2003). Synthesis and evaluation of iodine-123
labelled tricyclic tropanes as radioligands for the
serotonin transporter. Nuclear Medicine and
Biology, 30(7), 741-746.
Roger, G., Lagnel, B., Besret, L., Bramoulle, Y.,
Coulon, C., Ottaviani, M., Kassiou, M.,
Bottlaender, M., Valette, H., Dolle, F. (2003).
Synthesis, radiosynthesis and In Vivo evaluation
of 5-[3-(4-Benzylpiperidin-1-yl) prop-1-ynyl]-1,
3-dihydrobenzoimidazol-2-[11C] one, as a potent
NR 1A/2B subtype selective NMDA PET
radiotracer. Bioorganic and Medicinal
Chemistry, 11, 5401-5408. <a
href="http://dx.doi.org/10.1016/j.bmc.2003.09.0
36">[More Information]</a>
2002
Kassiou, M., Loc'h, C., Bottlaender, M., Mardon,
K., Ottaviani, M., Coulon, C., Katsifis, A.,
Maziere, B. (2002). (+)-[76Br]A-69024: a
non-benzazepine radioligand for studies of
dopamine D1 receptors using PET. Nuclear
Medicine and Biology, 29(3), 295-302.
Kassiou, M., Bottlaender, M., Loc'h, C., Dolle,
F., Musachio, J., Coulon, C., Ottaviani, M.,
Dannals, R., Maziere, B. (2002).
Pharmacological evaluation of a Br-76 analog of
epibatidine: a potent ligand for studying brain
nicotinic acetylcholine receptors. Synapse (New
York), 45(2), 95-104. <a
href="http://dx.doi.org/10.1002/syn.10087">[Mo
re Information]</a>
Kassiou, M., Loc'h, C., Dolle, F., Musachio, J.,
Dolci, L., Crouzel, C., Dannals, R., Maziere, B.
(2002). Preparation of a bromine-76 labelled
analogue of epibatidine: a potent ligand for
nicotinic acetylcholine receptor studies. Applied
Radiation and Isotopes, 57(5), 713-717.
2001
Kassiou, M., Eberl, S., Meikle, S., Birrell, A.,
Constable, C., Fulham, M., Wong, D., Musachio,
J. (2001). In vivo imaging of nicotinic receptor
upregulation following chronic (-)-nicotine
treatment in baboon using SPECT. Nuclear
Publications for Michael Kassiou
Medicine and Biology, 28, 165-175.
Kassiou, M., Mardon, K., Mattner,, F., Katsifis,
A., Dikic, B. (2001). Pharmacological evaluation
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