Weapons of Mass Destruction & Bioterrorism

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Weapons of Mass

Destruction

&

Bioterrorism

Ronald R. Blanck, D.O.

LTG, USA (Retired)

“…any explosive, incendiary, or poison gas, bomb, grenade, rocket having propellant charge more than four ounces, missile having an explosive charge of more than one quarter ounce, mine or device similar to the above…poison gas…disease organism…radiation.”

“…any weapon or device that is intended, or has the capability, to cause death or serious bodily injury…through the release of…poisonous chemicals…disease…or radiation….”

WMD :

Significant casualties from terrorist use of:

 Nuclear Device

 Chemical Device

Tabun (GA)

Sarin (GB)

 Soman (GD)

 Biological Device

Botulism Toxin

Anthrax

Plague

Ricin

 Large Conventional

Explosive Device

Terrorism Is…

“Warfare deliberately waged against civilians with the purpose of destroying their will to support either leaders or policies that the agents of such violence find objectionable.”

Lessons of Terror

- Caleb Cobb

KILL ONE

FRIGHTEN 10,000

-- Tom Clancy

The Sum of All Fears

Presidential Decision Directive 39

U.S. Policy on Counterterrorism

June 21, 1995

PRESIDENT

HOMELAND DEFENSE

Governor Tom Ridge

NATIONAL SECURITY COUNCIL

Coordination of Federal Agencies

FEMA

FBI

INCIDENT

CONTINGENCY PLANS

Crisis Management

FEDERAL

RESPONSE PLAN

Consequence Management

Definitions

• Crisis Management

– Measures to anticipate, prevent, and/or resolve a terrorist threat or incident

• Primary Responsibility: Federal Government

• Lead Federal Agency: FBI

• Consequence Management

– Measures to alleviate the damage, loss, hardship, or suffering caused by incident

• Primary Responsibility: State/Local Government

• Lead Federal Agency: FEMA, coordinating Federal

Consequence Management support to the state

Programs

• Domestic Preparedness

 Interagency effort directed by Congress

 AKA: Nunn-Lugar-Domenici City Training

• Consequence Management Program

Integration

 DoD efforts directed by SECDEF (DRID #25)

 Improve DoD Support for Response to WMD attacks

 Integrate National Guard and Reserve

Components

Purpose of Nunn-Lugar-

Domenici

• To enhance the capability of the Federal

Government to prevent and respond to terrorist incidents involving weapons of mass destruction

• To provide enhanced support to improve the capabilities of state and local emergency response agencies to prevent and respond to such incidents at both the national and local levels

Domestic Emergency Continuum

Greatest

Most Likely

Probability

IED --

Least Likely

-- IND

IBD --

ICD --

Impact

Civil Demo --

HURRICANE

Civil Disturbance --

HAZMAT --

Severe T-Storm --

MAJOR

FLOODING

-- Aircraft Accident

STATE & LOCAL FEDERAL

WMD

Tiered Disaster/Emergency Response

Federal Response

State Response

Local Response

Incident Commander

• Full response requires local, state, and federal assets

• State response includes National Guard

• Military support requires Total Force involvement

Federal WMD Response Assessment

Scenario

Radiological Threat

(Plutonium)

Summary: Terrorists place a radiation Dispersal Device which distributes plutonium over a populated area.

Nuclear Explosion Threat

(Uranium)

Summary: An improvised nuclear device (1.5KT) is exploded at midday in the vicinity of a state capitol building.

Biological Agent Threat

(Anthrax)

Summary: 100 grams of anthrax released into the air distribution system at a major airport.

Chemical Nerve Agent

Threat (GB)

Summary: 10 Gallons of Sarin is released on a busy morning in trash canisters at 5 Subway stations in a major city.

Chemical Nerve Agent

Threat (VX) (Persistent)

Summary: M23 Land mines (.8lb) placed in suitcases at major airport and exploded at midday

It’s not IF, It’s WHEN and WHERE?

* Bottom Line - we are not ready!

Biological Warfare

The intentional use of microorganisms or toxins derived from living organisms to produce death or disease in humans, animals, or plants

Biological Warfare

History

• 14th Century: plague at Kaffa

• 18th Century: smallpox blankets

• 1943: USA program established

• 1953: Defensive program established

• 1969: Offensive program disestablished

• 1979: Sverdlovsk Anthrax incident

• SE Asia: Yellow Rain

• London, Virginia: Ricin

BW Agreements

• 1925 Geneva Protocol

• 1969 Nixon renounces BW

• 1972 Biological Weapons Convention

• 1975 Geneva Conventions Ratified

Biological Weapons Policy

• No use under any circumstance

• Research limited to defensive measures

• We possess NO weaponized biologicals

• Previous weapons stocks destroyed

• Destruction supervised:

– USDA

– Dept of HEW

– DNR of AR, CO, MD

Destroyed U.S. Biological

Warfare Agents

• Lethal

– B. anthracis

– Botulinum toxins

– F. tularensis

• Anticrop

– wheat stem rust

– rye stem rust

– rice blast

• Incapacitating

– Brucella suis

– VEE virus

– SEB

– Q fever agent

The Sverdlovsk Incident

• April-May 1979

– 66 Anthrax fatalities

• 1988

– Soviets present data:

• 96 cases

• 79 gastrointestinal

• May 1992

– Yeltsin admits

“military developments”

Soviet BW Priorities

“Agents Likely to be Used”

• Smallpox

• Plague

• Anthrax

• Botulism

• VEE

• Tularemia

• Q Fever

• Marburg

• Influenza

• Melioidosis

• Typhus

“There were more

INSTITUTES working on

Plague in the USSR than

PERSONNEL working on

Plague in the USA”

-- Dr Ken Alibek

Advantages of BW:

Are Biologicals the Ultimate Weapon?

• agents easy to procure

• inexpensive to produce

• can disseminate at great distance

• agent clouds invisible

• detection quite difficult

• first sign is illness

• overwhelms medical capabilities

• simple threat creates panic

• perpetrators escape before effects

• ideal terrorist weapon

Acquisition of Etiologic Agents

• Multiple Culture Collections

• Universities

• Commercial Supply Houses

• Foreign Laboratories

• Field Samples or Clinical Specimens

Hypothetical Dissemination

50 kg agent, 2 km front, upwind of city of 500,000

Agent

RVF

TBE

Reach

1

1

Typhus

Brucella

5

10

Q fever >20

Tularemia >20

Anthrax >>20

KIA

400

9500

19000

500

150

30000

95000

WIA

35000

35000

85000

100000

125000

125000

125000

Hazardous Biologic Material

• Letters

• Packages

• Cultures

• Person – to - Person

Response

• Not Typical First Responders

• BIO First Responders

- Physician’s Office

- ER

- Clinics

• All Organizations Involved

Issues

• Rapid Detection

• Public Health

• Hospital Capacity

• Stockpiling

• Vaccine Production

Health Providers’

Responsibilities

 Awareness

 Presumptive Diagnosis

 Reporting

 Epidemiology

 Response

– Triage

– Prophylaxis

– Immunizations

– Treatment

 Risk Communications

It’s not a question of if...

26 February 1993, New York

20 March 1995, Tokyo

It’s not even a question of when…

11 September 2001, New York

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