Sex Differences and Defects Menstruation Circumcision Disorders of the Male Sex Organs Disorders of the Female Sex Organs Menstruation The sloughing off of built-up uterine lining that recurs in non pregnant women from menarche to menopause. The time from the beginning of one menstrual period to the beginning of the next (typically 28 days) Menarche: First menstrual cycle. Menopause: Last menstrual cycle. ___________________________________________________ • A woman who has two pregnancies will average about 500 menstrual cycles in her lifetime. • Menstrual fluid is a mix of blood, mucus, and cells from the endometrium (the lining of the uterus) • If fertilization does not occur, the uterine lining sheds off and is discharged as menstrual flow. Menstruation I. Menarche: • The initial onset of menstruation in life and signals the beginning of puberty. • Average age is about 12 years. ____________________________________________________________ II. Length and Frequency of the Menstrual cycle: • • • • Measured from the first day of menstrual flow to the day before the next flow begins. 24 to 42 days, Average of 28 days. Vary for a number of reasons: ▫ Travel to a different time zone. ▫ Sleep deprivation. ▫ Stress. ▫ Changes in diet and exercise. Menstruation Menstrual synchrony in humans is the convergence over several months of the dates of onset of menstrual periods among women who are in close contact with each other. Circumcision: Male • Surgical removal of the prepuce or foreskin of the penis. • For more than 3,000 years, Jewish families have been circumcising their newborn males on the eighth day after birth as a sign of their covenant with God. • Early 80’s-90’s: 84-91% • Today: 60% Medical value: • Uncircumcised boys have four times the risk of getting urinary tract infections in their first year. (the risk is still only 1 in 100) • Studies suggest that circumcised men have a reduced risk of contracting HIV and spreading the disease. Circumcision: Male • Others oppose what they see as an unnecessary, traumatic surgical procedure that poses possible complications including hemorrhage, infections, mutilation, shock, psychological trauma, and even death in rare cases. Circumcision: Male Historically: • The only surgical procedure that is routinely performed without first administering analgesia or anesthesia. Circumcision: Female Defined: Ritual excision of the vulva. • Misnomer- The vulva is not a foreskin. • More correctly referred to as Female Genital Mutilation. • This would be better compared with a complete removal of all the sexually sensitive skin on the male penis which is far more drastic than male circumcision. Disorders of the Male Sex Organs Prostate Cancer: Second only to skin cancer as a leading cancer killer among American men. • One in six American men will develop prostate cancer. • More than 80% of men with prostate cancer are over the age of 65. Prostatitis: Inflammation of the prostate gland, common disorder that may occur in men of any age. Disorders of the Male Sex Organs Benign Prostatic Hyperplasia (BPH): Noncancerous enlargement of the prostate. • Happens naturally with ageing. • As the prostate enlarges, the surrounding capsule stops it from expanding, causing the gland to press against the urethra. Testicular Cancer: Cancer of the testis. • Relatively few men routinely perform self-examination. Disorders of the Male Sex Organs Testicular Torsion: Occurs when a testis is rotated, twisting the spermatic cord. • May cut off blood flow to the testicles and surrounding structures. Epididymitis: Inflammation of the epididymis. • Infection is the most common causal factor. Disorders of the Male Sex Organs Penile Cancer: Cancer cells are found on the skin and in the tissues of the penis. • Very rare: Accounts for less than ½ percent of all malignancies in the United States. • Occurs in men over the age of 50 Peyronie’s Disease: Characterized by a bending or curving of the erect penis. • Many researchers believe it is caused by damage to the erectile bodies. Disorders of the Female Sexual Organs Endometriosis: Condition in which endometrial tissue grows in pelvic regions outside the uterus. • Non-life-threatening condition. • Typically the tissue growth occurs in the pelvic area. • 10 to 20% of women during their reproductive years. • 15-50% among infertile women. Endometrial Cancer: Cancer originating in the lining of the uterus. • Nearly all of these life-threatening cancers occur in the form of adenocarcinomas (tumors of glandular cells). • Most common malignancy of the female reproductive organs. Endometriosis Disorders of the Female Sexual Organs Uterine Fibroids: Balls of solid tissue that can grow inside the uterus, within the uterine wall, or outside the uterine wall. • Can range in size from a grain of rice to a basketball. • Affects up to 25% of women over the age of 30. • African American women are three to nine times more likely to be affected. • Cancerous in less than 1% of the cases. Cervical Cancer: Cancer of the lower portion of the uterus, begins in the lining of the cervix and does not form suddenly. Uterine Fibroids Disorders of the Female Sexual Organs Ovarian Cysts: Balloonlike swellings of fluid contained within an envelope of ovarian tissue. • Most are harmless and will go away without any treatment. Ovarian Cancer: Most common ovarian cancer in women age 55-80 is adenocarcinoma. Disorders of the Female Sexual Organs Vulvar Cancer: Most often affects the inner edges of the labia majora or the labia minora. • Less often vulvar cancer occurs on the clitoris or the Bartholin’s glands. • Second most common type of vulvar cancer (4%) is melanoma, the deadliest type of skin cancer. Disorders of the Female Sexual Organs Vaginitis: Inflammation of the vagina, typically caused by bacteria or yeast infection. Breast cancer: Breast cancer represents 30% of all female cancers, affecting approximately 110 women per 100,000.