Midwest Regional Chapter Society of Toxicology Spring 2004 Newsletter Join Your Colleagues at the May 14th Conference! Inside the Newsletter Spring Conference on Contemporary Issues in Toxicology …….. 2 Directions to the Spring Conference and Registration Form…….. 3 Business Opportunities for the Entrepreneur…………………….. 4 Two Outstanding Nominees for 2004 DuBois Award………..…....5 Invitation to Join Midwest’s Dynamic SOT Chapter……………...6 Application for Renewal of MRC-SOT Membership……………...7 Application for Membership in MRC-SOT………………………..8 2003 Young Investigator Award Recipient’s Abstract..…..……….9 Call for Posters for 2004 Victor Drill Award………………….…..10 Student Activity Committee Report & Your 2004 Candidates……11 Photo of Officers at MRC-SOT Breakfast at SOT Baltimore……..12 Your Officers & Committee Chairs…...…………………………...13 1 Contemporary Issues In Toxicology Friday, May 14, 2004 ~PROGRAM~ Registration 7:30 AM – 8:00 AM GABA Disorder, PCBs, and Autism: Possible Interplay of Genes and Environment 11:45 AM – 12:30 PM Issac Pessah, Ph.D. U. C. Davis Autism Center Davis, CA Welcome Introduction 8:00 AM – 8:15 AM Dr. Reid Patterson President, MRC/SOT Reid Patterson Consulting, Inc. Luncheon*, Exhibitors Displays & Business Meeting Presentation of the DuBois Award For an Outstanding Career in Toxicology by a Prominent Midwest Scientist Introduction of 2004-2005 Officers 12:45 AM – 2:30 PM *MORNING PROGRAM* Vaccines & Autism 8:15 AM – 11:45 AM Chair: Dr. Bruce Trela Vice President, MRC-SOT Abbott Laboratories *AFTERNOON PROGRAM* Clinical Overview of Autism 8:15 AM – 9:00 AM Glenis Benson, Ph.D. Autism Spectrum Disorders Madison, WI Development of Biologicals & Immunotoxicology 2:30 PM – 3:00 PM Chair: Dr. Bruce Trela Abbott Laboratories Does the MMR Vaccine Cause Autistic Spectrum Disorder? 9:00 AM – 9:45 AM Kumanan Wilson, M.D., M.SC. Toronto General Research Institute Toronto, Ontario Biologics Safety Assessment Strategy 2:30 PM – 3:15 PM Lauren Black, Ph.D. Charles River Laboratories Reno, NV Immunomodulation in Non-Human Primates 3:15 PM – 4:00 PM Jeanine Bussiere, Ph.D. Amgen Thousand Oaks, CA Refreshment Break 9:45 AM – 10:15 AM Neurodevelopmental Disorders Following Childhood Vaccines 10:15 AM – 11:45 AM Mark Geier, M.D., Ph.D. with son David Genetic Centers of America and MedCon Closing Remarks Dr. Bruce Trela President-Elect, MRC-SOT 4:00 PM Reception/Poster Session/Exhibits Tisha Heiden, 2003 Young Investigator, and other student presentations 4:00 PM – 6:00 PM *Lunch is assured only to those who pre-register by May 7, 2004 2 MEETING INFORMATION Fees Hotel Rooms Regular Member: $90 Non-Member: $120 Full-Time Students: $10 Rooms are not being held for this conference Reservations can be made by calling: (847) 634-0100 Directions to Conference Site Lincolnshire Marriott Resort 10 Marriott Drive Lincolnshire, Illinois 60069 (847) 634-0100 From the North: I-94 south; exit Half Day Road; turn right (west); turn left on Milwaukee Avenue; turn left on Marriott Drive. From the South: I-94 north; exit Half Day Road; turn left (west); turn left on Milwaukee Avenue; turn left on Marriott Drive From the West: I-90 east; I-294 north; I-94 north; exit Half Day Road; turn left (west); turn left on Milwaukee Avenue; turn left on Marriott Drive Registration Form: Return the form below with payment to MRC-SOT by 5/7/03 to: Ms. Linda Tam, Treasurer MRC-SOT, 1228 Sherwood Rd., Glenview, IL 60025 ------------------------------------------------------------------------------------------------------------------------------------MRC/SOT 2004 Spring Meeting Registration Form Name_________________________________ Vegetarian Meal? _____Yes _____No Title/Position/Company______________________________________________________ Phone Number____________________E-mail address ____________________________ Address___________________________________________________________________ City______________________________________State_____________Zip____________ 3 Business Opportunities for the Entrepreneur With the MRC-SOT Exhibition Tables: New this year is the opportunity to display your services and benefits to the over 100 attendees that typically support the Spring MRC-SOT conference. A limited number of tables will be available for your pamphlets, materials, demonstrations, etc. for only $300. Attendees will be able to visit the exhibits during the lunch, business meeting, coffee breaks and the afternoon reception. Build your business, market your products and services, recruit key professionals, or whatever will help you be an even greater success! Conference Sponsorships: Show the toxicology community throughout the Midwest that your firm is a key contributor to the growth of knowledge in toxicology through your products and services. Become a Platinum Sponsor with a tax-deductible contribution of $2,500 or more, a Gold Sponsor with a contribution of $1,000 to $2,499, a Silver Sponsor with a contribution of $500 to $999, or a Bronze Sponsor with a contribution of $200 to $499. Contributors will be recognized on conference materials, MRC-SOT publications and during the conference. Donations under $200 will be recognized as Contributors. Award Sponsorships: The MRC-SOT provides several awards each year. A regional scientist, who has dedicated his/her career to the management, education, and/or research in toxicology, contributing significantly to our knowledge in hazard assessment and risk management, is honored each year as the DuBois Award recipient with an accompanying $500 honorarium. The student presenting the best poster at our spring meeting receives expenses to travel to the next annual SOT meeting, up to $1,500. The winner of our Young Investigator Award is provided $1,500 to support research and other expenses. If you wish to recognize these important efforts by sponsoring an award, you may donate the amount of one or more awards. Meeting fees alone cannot offset the cost of the quality symposia with nationallyrecognized speakers that characterize the Spring Conference of the MRC-SOT. Consider supporting this effort! Contact Ms. Linda Tam or other officer of MRC-SOT. THANKS! Reid Patterson, President, MRC-SOT (2003-2004) reidpattersonconsulting@comcast.net 847-548-7549 4 Two Outstanding Nominations for the 2004 DuBois Award from MRCSOT [The award consists of an engraved plaque and an honorarium, both presented at the annual Spring Meeting of the MRC/SOT] Richard E. Peterson, Ph.D. Dr. Peterson is has spent over 30 years in association with the University of Wisconsin, educating 23 Ph.D. students and over 25 post-doctoral students in toxicology and pharmacology. A prominent teacher and researcher, the latter focusing on the mechanism of dioxin and PCB toxicity in laboratory animal models and its risk extrapolation to humans and freshwater fish populations in the environment. Dr. Peterson is a Professor, Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, where he has taught and led research since 1984. Dr. Peterson also is the Director, Endocrine Disruption International Cooperative Research (EDICOR) program at the University of Wisconsin (2003-present), a member of the External Advisory Board, NIEHS Marine and Freshwater Biomedical Center, Oregon State University, a member of the Expert Registry, NIEHS, National Toxicology Program, Center for the Evaluation of Risks to Human Reproduction (1998-Present), a member of the External Advisory Board, NIEHS Superfund Program Project, Duke University (2001-present) and Chairman, Board of Publications, Society of Toxicology (2002-present). Dr. Peterson is a toxicology consultant for the Science Advisory Board, U.S. Environmental Protection Agency (1986-present), Coordinator, Biotechnology Subprogram, Sea Grant Institute, University of Wisconsin (1996-present), and on the External Advisory Board, NIEHS Superfund Program Project, Health Effects of Chlorinated Compounds, University of Florida-Gainesville (1997-present). From 1998-2002, Dr. Peterson was Deputy Director, NIEHS Center, Developmental and Molecular Toxicology, University of Wisconsin. Other previous responsibilities included membership on the Board of Scientific Counselors, National Toxicology Program (1997-9), Chairman, Pharmacology/Toxicology Division, School of Pharmacy, University of Wisconsin (1993-5), Director, BS program in Pharmacology & Toxicology, School of Pharmacy, University of Wisconsin (1985-2002), Associate Professor (1979-84) and Assistant Professor (1975-9), Pharmacology/Toxicology Division, School of Pharmacy, University of Wisconsin, Instructor (1973-5), Research Associate (1972-3) and NIH Pre-doctoral Trainee (1967-72), Department of Pharmacology, Medical College of Wisconsin. Dr. Peterson received his B. S. from the University of Wisconsin in Madison and his Ph.D. in Pharmacology from the Marquette University Medical School in Milwaukee. Dr. Peterson’s research and teaching have been recognized by his receipt of the Research Career Development Award – NIEHS, the Frank R. Blood Award - Society of Toxicology, the Merit Award - Society of Technical Communication and the MERIT Award – NIEHS. Dr. Peterson has served on the editorial boards of the following journals: Journal of Applied Toxicology, Journal of Biochemical Toxicology, Toxicology and Applied Pharmacology, and Chemosphere. He is presently associate editor for Birth Defects Research, Part A: Clinical & Molecular Teratology. Dr. Peterson has presented 116 invited presentations, 282 scientific abstracts at scientific symposia, 206 publications in the scientific literature, and has authored 28 book chapters and edited one textbook. Frederick M. Radzialowski, Ph.D. Dr. Radzialowski is President of FMR Research Associates, which he formed in 1993. Dr. Radzialowski provides scientific and management consultation to the Pharmaceutical Industry in the areas of R&D Discovery and Development strategy, IND and NDA registration strategy, IND and NDA document review, Expert opinion and Executive Summary preparation, training in the Drug Development Process and R&D Management- issue diagnosis and problem solving. From 1989 to 1993, Dr. Radzialowski served as Vice President, Product Safety and Metabolism for G.D. Searle’s R&D organization in Skokie. During these 4 years, he directed and managed a worldwide function of about 250 scientists and professionals. Administrative responsibilities 5 included Toxicology, Pathology, Drug Metabolism and Pharmacokinetics and Laboratory Animal Resources in the U.S. and Belgium. He had preclinical scientific safety oversight worldwide and was responsible for a $25,000,000 operating and $2,900,000 capital budget, as well as being involved in R&D executive committee activities (e.g., LRP, EM, Program reviews, IND and NDA reviews). Dr. Radzialowski developed a worldwide team operation to allow work to be shared between groups in the U.S. and Europe providing efficiency, flexibility and rapid response, and expanded scientific capability to state-of-the-art by careful staff selection, equipment, purchases and scientific contact with experts in the field. Earlier responsibilities with Searle included Senior Director for Product Safety Assessment (1985-89), Director, Biological Research (1980-5), Section Head, Cardiovascular & Renal Diseases (1976-80), Group Leader in Metabolic & Endocrine Diseases (1975-6) Senior Research Investigator (1974-5) and Research Investigator (1967-74). Dr. Radzialowski received a B.S. in Pharmacy and a M.S. degree in Pharmacology from Wayne State University and his Ph.D. in Pharmacology from Purdue University. Dr. Radzialowski is or has been a reviewer for the following professional journals: Biochemical Pharmacology, J. Medicinal Chemistry, Life Sciences and Toxicology & Applied Pharmacology. Dr. Radzialowski has been a recipient of the Rexall Outstanding Achievement Award, the McKesson & Robbins President Award, a Distinguished Alumnus Award - Purdue University and Wayne State University, plus memberships in the Omicron Delta Kappa Honor Society, Rho Chi Honor Society and the Sigma Xi Honor Society. Dr. Radzialowski has presented at a dozen invited lectures, 15 platform presentations, 12 publications and was a coeditor for 2 books. Invitation to Join or Renew Membership with Midwest’s Dynamic SOT Chapter Membership Committee Update As most of the MRC/SOT communications are now electronic, please make sure that you update your contact information if applicable. This can be done via the National SOT website (www.toxicology.org) or by contacting the Membership Chair: Robin Guy (rcg@robinguy.com). If you need to renew your membership, you can either use the attached renewal form, or renew over the website. Keeping membership at the level that we are used to will require a group effort. Please take the time to copy the attached Membership Application and circulate it to those who you think would benefit from MRC/SOT membership. For those of you who are already members, please renew promptly after receiving the renewal instructions. You can renew membership at any time by logging in to the National SOT website. Credit cards are now accepted on the website! We will miss our friends and colleagues who will be relocating. If you are planning on relocating, and would like to keep in touch with current MRC activities, consider keeping your MRC membership. It is not a requirement to live or work in the MRC area. All you need to do is keep your contact information up-todate, and we will continue to send you newsletters and meeting information as they are published. If you have any questions on membership, please contact Robin Guy at the e-mail address above, or call (847) 295-9250. 6 MIDWEST REGIONAL CHAPTER OF THE SOCIETY OF TOXICOLOGY MEMBERSHIP RENEWAL FORM The MRC-SOT was formed in 1981 and was one of the first regional chapters chartered by the Society of Toxicology. If you have an active and professional interest in toxicology, you may become a member of MRC-SOT. The annual fee for full membership is $25.00 and the annual fee for student membership is $10.00. The objectives of the MRC-SOT are: 1. To serve as the focal point for toxicological interests in the Midwest. 2. To encourage interactions among toxicologists in government, industry, and academia. 3. To sponsor scientific and educational programs in toxicology. The MRC-SOT sponsors at least two annual scientific meetings (Spring and Fall). These have included the successful "Contemporary Topics in Toxicology" Symposia which attract speakers and participants nationwide. The chapter also confers the annual Kenneth P. Dubois Award to an outstanding toxicologist in the Midwest. Please complete this form in its entirety. Membership in the Midwest Regional Chapter does not constitute membership in the national Society of Toxicology. Send this form, and a check in the appropriate amount (made payable to "MRC-SOT") to: Robin Guy, MS, DABT MRC-SOT Membership Chair Robin Guy Consulting, Toxicology and Product Safety Assessment, P.O. Box 830, Lake Forest, IL 60045 Name: ___________________________________________________________________________________ Employer (School): _________________________________________________________________________ Business (School) Address: __________________________________________________________________ ________________________________________________________________________________________ Telephone: ________________________ Fax: _______________________ E-mail _____________________ Home Address (optional): ____________________________________________________________________ Home Telephone (optional): __________________________________________________________________ Title (Year of School): ______________________________________________________________________ Are you a member of National SOT? (circle one) Yes No Name: ____________________________________________________________________________ Signature: _________________________________________________ Date: ___________________ *Note: School information applies to full-time students only. 7 MIDWEST REGIONAL CHAPTER OF THE SOCIETY OF TOXICOLOGY APPLICATION FOR MEMBERSHIP The MRC-SOT was formed in 1981 and was one of the first regional chapters chartered by the Society of Toxicology. If you have an active and professional interest in toxicology, you may become a member of MRC-SOT. The annual fee for full membership is $25.00 and the annual fee for student membership is $10.00. The objectives of the MRC-SOT are: 1. To serve as the focal point for toxicological interests in the Midwest. 2. To encourage interactions among toxicologists in government, industry, and academia. 3. To sponsor scientific and educational programs in toxicology. The MRC-SOT sponsors at least two annual scientific meetings (Spring and Fall). These have included the successful "Contemporary Topics in Toxicology" Symposia which attract speakers and participants nationwide. The chapter also confers the annual Kenneth P. Dubois Award to an outstanding toxicologist in the Midwest. Please complete this application in its entirety; do not cross reference to the curriculum vitae. Membership in the Midwest Regional Chapter does not constitute membership in the national Society of Toxicology. The membership fee will be refunded if the application for membership is not accepted. Send this application, your curriculum vitae (if available), and a check in the appropriate amount (made payable to "MRC-SOT") to: Robin Guy, MS, DABT MRC-SOT Membership Chair Robin Guy Consulting, Toxicology and Product Safety Assessment, P.O. Box 830, Lake Forest, IL 60045 Name: ___________________________________________________________________________________ Employer (School): _________________________________________________________________________ Business (School) Address: __________________________________________________________________ ________________________________________________________________________________________ Telephone: ________________________ Fax: _______________________ E-mail _____________________ Home Address (optional): ____________________________________________________________________ Home Telephone (optional): __________________________________________________________________ Title (Year of School): ______________________________________________________________________ Job Description (Area of Study): ______________________________________________________________ ________________________________________________________________________________________ Professional (Academic) Experience: ___________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ Academic Training *(including institution name, dates of attendance, major and minor subject, and degrees): 1. Undergraduate: __________________________________________________________________________ ________________________________________________________________________________________ 2. Graduate: ______________________________________________________________________________ ________________________________________________________________________________________ Are you a member of National SOT? (circle one) Yes No Name one person who can attest to your interest in Toxicology: Name: ________________________________________ Telephone Number: __________________________ Signature of Applicant: _____________________________________________ Date: ___________________ *Note: School information applies to full-time students only. 8 Research Contributions of Your 2003 Young Investigator Awardee, Tisha Heiden, Who Will Present During May 14th Reception: Chronic Exposure to Low Doses of TCDD Alters Reproductive Success of Zebrafish. Tisha King Heiden, Barbara Wimpee, Reinhold Hutz, and Michael J Carvan, III. UW-Milwaukee Great Lakes WATER Inst. and Department of Biological Sciences. Dioxins are prevalent within the environment and are formed as by-products from several anthropogenic processes. 2,3,7,8-tetrachloro-dibenzo-p-dioxin (TCDD) in particular is especially toxic, and has been shown to act as a teratogen, embryotoxin, carcinogen, immune system suppressor, and endocrine disruptor. TCDD has the potential to modulate several biological processes that impact growth and development, and fish are among the most sensitive vertebrates to its developmental toxic effects. Wild fish populations exposed to high levels of TCDD have reduced reproductive success, which is thought to be the result of reduced egg production and poor offspring survival. The long-range goal of this project is to gain a better understanding of the mechanisms by which TCDD modulates reproductive function in fishes, using zebrafish (Danio rerio) as a model organism. Adult female zebrafish were fed different concentrations of TCDD (10 – 100 ng TCDD/g food, ppb) for several weeks, and subsequently spawned with untreated males to determine effects of TCDD exposure on egg production and survival of offspring. Females did not exhibit an overt toxic response (i.e., reduced condition factor, arrest of spawning, uncoordinated fin movements, fin necrosis, or skin discoloration or lesions), but exposure to TCDD did affect the ovary. There was a significant decrease in the ovosomatic index of females from all treatment groups compared to control (p<0.001), and many females from the highest treatment group (100 ppb) showed severe ovarian necrosis. However, only females from the highest treatment group showed a significant decrease in egg production (p<0.05). On average, females from this group produced 50% fewer eggs than normal (as assessed during baseline experiments). Since egg production was highly variable between treatment groups, even prior to TCDD exposure, lack of an observed effect on egg production in the lower treatment groups could be due to small sample size. Maternal transfer of TCDD resulted in a significant decrease in the survival of offspring (24 hpf and 6 dpf), and surviving larva from females in the two highest treatment groups (60 and 100 ppb) showed a significant increase in the incidence of early life stage (ELS) toxicity (toxic response resembled blue-sac disease and was accompanied by erratic swimming behaviors). ELS toxicity was first observed at 4 dpf, and the incidence increased over time in a dose-dependent manner. Preliminary tissue distribution and translocation studies using 3H-TCDD (270 ng TCDD/g food) reveal that TCDD accumulates in ovary and brain, reaching steady state after three weeks of exposure. While TCDD accumulates in digestive tract organs (including the liver), the carcass (including muscle tissue) did not accumulate appreciable concentrations of TCDD perhaps due to the small amount of adipose tissue present in zebrafish muscle. Maternal transfer results in the accumulation of TCDD in eggs, and there is no appreciable loss of TCDD from embryonic tissues between 2 hpf and 7 dpf. Following three weeks maternal exposure, the average TCDD concentration in eggs was 1.3 0.05 pg TCDD/mg egg. While this is less than the LC50 for zebrafish eggs (2.5 pg TCDD/mg egg), it is sufficient to induce ELS toxic response and reduce offspring survival. In summary, reproductive success of female zebrafish was significantly impacted when they were fed concentrations of TCDD that did not induce an acute toxic response or alter spawning activity. These results support hypotheses that maternal transfer of low levels of toxicants such as TCDD can affect recruitment in natural populations due to their negative effects on offspring survival, even when overall egg production is not greatly impacted. On-going investigations into the molecular mechanisms by which TCDD exerts its reproductive toxic effects will hopefully contribute to our understanding of the dangers that endocrine disrupting chemicals such as TCDD have on vertebrates systems, and provide insight into ways that we can protect wildlife, and ourselves, from such toxicants. Since it is often the disruption of 9 normal cellular and molecular pathways that lead to a chemical’s toxic effect, we are using cDNA microarray technologies, with the aid of bioinformatics tools, for global analysis of changes in gene expression due to TCDD exposure. Patterns of gene expression from TCDD-treated and normal states will be compared to identify differentially expressed genes that may play a key role in the reproductive toxic effects of TCDD. Additionally, since it is known that TCDD disrupts serum estrogen levels, and that the ovary is a major target site of TCDD toxicity, I will also use real time RT-PCR to determine the effects of exposure to TCDD on the expression of genes important in estrogen biosynthesis. These results will then be compared to whole-body estradiol and vitellogenin concentrations to further characterize the mechanisms by which TCDD disrupts estrogen biosynthesis in zebrafish. These experiments provide the necessary framework for testing a number of emerging hypotheses regarding the mechanisms by which TCDD exerts its reproductive toxic effects by integrating the physiological hormonal endpoints with the global analysis of gene expression. VICTOR A. DRILL AWARD **Call for Abstracts** The Spring Meeting Poster Session provides an opportunity for toxicologists to present research that might be outside the scope of the symposium. The Victor A. Drill Award is bestowed upon the first author of the best poster presentation. In line with our charter, the objective of the poster session and the award is to encourage toxicology research and education. The recipient can be a student, post-doctoral fellow or industry professional from any academic, governmental or industrial institution in the Midwest. The recipient must be a member of the MRC/SOT or in the process of applying for membership. Junior staff and students are particularly encouraged to participate. Consequently, preference will be given to participants 35 years of age or younger. The Awards Committee will judge the posters and the winner will be announced at the conclusion of the poster session. Announcements will also appear in the MRC/SOT newsletter. Since many MRC/SOT meeting attendees do not regularly attend the national meetings, it is permissible to present a poster that has been previously presented there. The first place prize is a trip to next year’s Society of Toxicology meeting (March 21-25, 2004) in Baltimore, Maryland (up to $1500 for registration, airfare and lodging). The second place prize is up to $100 towards the toxicology textbook of your choice. If you are interested in presenting a poster at this year’s meeting, fill out the enclosed abstract form and submit it to: Charles Mattis Abbott Laboratories Dept. R468, Building AP13-A 100 Abbott Park Road Abbott Park, IL 60064-6103 *If you want to be considered for the Victor A. Drill Award, make sure to mark the appropriate box on the abstract form. 10 THE STUDENT ADVISORY COMMITTEE Greetings everyone! The MRC-SOT will be searching for a new Regional Chapter student representative to serve on the Student Advisory Committee (SAC). As an ad hoc committee of the National Society of Toxicology, the SAC was created to serve as student liaisons between the Regional and National SOT in order to promote student participation and membership. In order to encourage student participation in the MRC-SOT, our Regional chapter is exploring the possibility of establishing university-based clubs and potentially launching an MRC-SOT website link where students can interact with toxicologists in our chapter. If you are interested in applying for the MRC-SOT student representative position and are excited about promoting student involvement and participation in our Regional Chapter, please feel free to contact me or any of the MRC-SOT Executive Committee Members listed in this newsletter. Speaking from experience, I can honestly say that being the student representative for the MRC-SOT has been the highlight of my graduate school career! It is a great way to interact with other students, develop leadership skills, and play an important role in student initiatives of our Regional chapter. Don’t miss out on this fantastic opportunity! If you have any questions regarding applying for the MRC-SOT student representative or are interested in becoming a student member, I would be glad to talk with you! See you on May 14th! Christina Wilson MRC-SOT Student Representative Purdue University 406 South University West Lafayette, IN 47907 (765) 494-7466 wilsonc@purdue.edu EXECUTIVE COUNCIL ELECTIONS COMING UP! Nominations have been submitted for the upcoming MRC/SOT Executive Council election. The offices that are being filled during this spring’s election are President-Elect, Treasurer and two Councilor positions. The President-Elect serves as a member of the Executive Council and as Chairperson of the Program Committee and will accede to the Presidency the following year. The Treasurer keeps accurate records of all transactions and provides regular updates to the Executive Council and the chapter members. Councilors assist in governing the affairs of the MRC/SOT and act as Chairpersons for the Standing Committees (Membership, Nominating, Education, Awards, Audit and Communications). The candidates in the running are: President-Elect: Don Korte, Concordia University Kevin Williams, Covance Secretary: Councilor Nabil Al-Humadi, IIT Research Institute Steve Hooser, Purdue University Bill Johnson, IIT Research Institute Chuck Mattis, Abbott Laboratories Robin Guy, Robin Guy Consulting Barbara Struthers, BJ Struthers Consulting Ballots will be sent out shortly. Please make your voting selections and return your ballot as soon as possible. These elections are held every spring, so if you’re interested in running for office next year or know someone who might be, more opportunities are on the way! Simply access our web page and download the nomination form. It is a great opportunity to get involved and meet your fellow toxicologists! 11 MRC/SOT BREAKFAST AT NATIONAL MEETING IN BALTIMORE The MRC/SOT informal breakfast gathering at the Marriott Hotel on Wednesday morning March 24th was a great success! It was a wonderful opportunity to catch up with acquaintances from the chapter and meet new toxicologists from both the Midwest area and across the country. As a result of the positive response we had to this event, we plan to continue to make this an annual tradition. Thanks to all of you who were able to come by and have breakfast with us! Front (Lt. to Rt.): Robin Guy, Reid Patterson, Dan McLain; Rear: Bruce Trela, Randy White, Don Korte. Not shown are: Sue Schantz, Mike Schlosser, Linda Tam, Christina Wilson VISIT YOUR CHAPTER ONLINE! www.toxicology.org/memberservices/regionalchapter/midwest/ (update your bookmarks) 12 2003-2004 MRC-SOT EXECUTIVE COUNCIL President: Reid Patterson Telephone: (847) 548-7549 Student Representative Christina Wilson Telephone: (765) 494-7466 President-Elect: Bruce Trela Telephone: (847) 937-8106 Councilors: Robin Guy Telephone: (847) 295-9250 Past President: Michael Schlosser Telephone: 847-682-6141 Dan McLain Telephone: 608-824-3730 x 203 Secretary: Don Korte Telephone: (262) 243-4268 Susan Schantz 217-333-6230 Treasurer: Linda Tam Telephone: (847) 998-4712 Randy White Telephone: (847) 270-5459 2003 - 2004 COMMITTEE ASSIGNMENTS (Thanks to everyone for your support!) Program Committee Chair: Bruce Trela Membership Committee Chair: Robin Guy Audit Committee Chair: Dan McLain Nominating Committee Chair: Mike Schlosser Awards Committee Chair: Sue Schantz Charles Mattis Communications Committee Chair: Reid Patterson Randy White Finance Committee Chair: Linda Tam SAC Representative Christina Wilson (Purdue) The MRC-SOT Newsletter is published biannually in both print and electronic formats as a service to the toxicology community of the Midwest. Contributions are welcome! Please address any questions, comments or contributions to: Reid Patterson, Editor President, Reid Patterson Consulting, Inc. 32768 N. Stone Manor Drive Grayslake, IL 60030-3053 Phone: 847-548-7549 Fax: 847-548-7594 Email: reid@reidpattersonconsulting.com Website: www.reidpattersonconsulting 13 14