IEEE TRANSACTIONS ON INDUSTRY APPLICATIONS, VOL. 51, NO. 1, JANUARY/FEBRUARY 2015 Esteban J. Pino, Senior Member, IEEE, Astrid Dörner De la Paz, Student Member, IEEE, and Pablo Aqueveque, Member, IEEE Presenter: Kai-Min Liang Advisor: Dr. Chun-Ju Hou Date:2015/12/16 Outline Introduction Research motivation Sleep Disturbances In Miners Measurement System Signal Processing And Analysis Results Conclusion 2 Introduction Mining has rapidly grown because of globalization Having extended hard working shifts Without specialized medical supervision These conditions prevent having a restful sleep, affect a worker’s job performance. 3 Introduction During sleep The body restores main nervous system functions to successfully perform daily activities. Memory Learning Reaction time among others 4 Introduction Twenty-eight percent of the world population suffer from nocturnal diseases Sleep apnea hypopnea syndrome (SAHS) 9% woman 24% man Brain damage Cardiovascular problems Hypertension and arrhythmia 5 Introduction Polysomnography (PSG) Different signals are recorded simultaneously Airflow, SpO2 Respiratory effect EEG, ECG, EMG Expensive and time-consuming Unsuitable for continuous monitoring 6 Introduction Actigraphy Measure sleep parameters and estimate sleep problems Unobtrusive method The hardware is too simple and only considers sleep efficiency to estimate sleep quality. 7 Introduction Pressure sensor arrays Record the time in bed (TB) and the BMs and respiratory signal Noninvasive monitoring Installed in standard beds Continuous monitoring of sleep quality 8 Research motivation Portable and noninvasive device based on pressure sensors to monitor sleep parameters Time in bed(TB) Body movements(BMs) Respiratory rate (RR) Apneas 9 Research motivation From these parameters, possible to report the sleep interval duration Sleep intervals longer than 20 min(SI>20) Sleep intervals short than 20 min(SI <20 ) From six volunteers and one SAHS-diagnosed patient show the potential 10 Sleep Disturbances In Miners Miners are long hour shifts and high-altitude efforts The shift work at Chilean mines Four days of work at a mining facility and three days to rest Seven days of work at a mining facility and seven days to rest Some accident caused by fatigue is higher in shift workers than nonshift workers 11 Sleep Disturbances In Miners The most innovative system considers EEG to estimate the alertness status of an operator. Scan the workers and try to predict an alertness status when people are working Do not collect any information of fatigue or somnolence Need an objective system to improvements on a worker’s sleep quality 12 Measurement System The system is divided into five stages 13 Measurement System A. Sensor Array 24 force sensor resistors (FSRs) Placed into three rows and eight columns Active area of each sensor is 38.1 mm × 38.1 mm Total sensing area of the array is 300 mm × 900 mm Must cover the width of the thorax Comfortable to the patient Safe to use 14 Measurement System B. Analog Signal Multiplexing Three eight-channel multiplexers Reduce the size of the hardware Multiple ADC ports available in the microcontroller C. Resistance –Voltage Transducer An inverting amplifier produces the resistance– voltage transduction. 15 Measurement System D. ADC Three ADC channels of the microcontroller are configured with 8 bits of conversion. Sampling frequency of each channel is 250 Hz Sampling rate per sensor is 31.25 Hz E. Serial Communication Serial communication at 38.4 K baud to a 2-GB microSD card 16 Signal Processing And Analysis A. Sleep Parameters Fig. 5. Twenty-four signals obtained from the pressure sensor array. The BMs and the apnea episodes appear in most of the signals. 17 Signal Processing And Analysis A. Sleep Parameters TB calculation: indicates the time spent or devoted to sleep BM detection: during sleep change in position or the movement of an extremity Remove those sections for the respiratory algorithm Appear as high frequency and high amplitude signals Detected by observing amplitude changes in a 2-s window At least three signals have to large amplitude change over a threshold 18 Signal Processing And Analysis A. Sleep Parameters a. Full-night-sleep record b. Vertical red lines represent the BM detections along the record. 19 Signal Processing And Analysis A. Sleep Parameters Automatic signal selection: changes position, channel that detects the best respiratory signal Rejecting saturated signals, discarding the channels with a mean above or below a previously determined threshold, and leaving only valid signals. Selection of the signal with the smallest kurtosis along the segment. 20 Signal Processing And Analysis A. Sleep Parameters RR calculation: corresponds to the number of respiratory cycles per minute Change with sex, age, or the wake/sleep stage Calculated by inverting the time intervals between two consecutive peaks in the selected respiratory signal. 21 Signal Processing And Analysis A. Sleep Parameters Apnea detection: defined as the absence of airflow for at least 10s Between two BMs, all the valid signals are added together, and the standard deviation is calculated. Compared with its moving average Current value is less than 40%, it is marked as a possible apnea event. After that, a 10-s window adds the events. Best in terms of the sensitivity to detect the events (Se) and the positive predictivity (+P) to avoid false alarms. 22 Signal Processing And Analysis B. Sleep Quality Indexes During sleep, the subject goes through different stages. Rapid eye movement (REM) Deepest stage of sleep Muscle atony Lasts between 20 and 30 min Non-rapid eye movement (NREM) Characterized absence of REM Shallow stages of sleep Muscle contraction A typical sleep cycle lasts about 90 min. 23 Signal Processing And Analysis B. Sleep Quality Indexes Sleep interval duration: sleep interval duration is calculated between two consecutive BMs SI > 20: deep-sleep stage (REM) SI < 20: shallow-sleep quality 24 Signal Processing And Analysis B. Sleep Quality Indexes Sleep depth from BMs: BMs may be used as an estimate of the sleep depth A 20-min sliding window adds the number of BMs along the measurement. Low number of added BMs indicates a deeper sleep stage. A moving average helps visualize the sleep cycles. 25 Signal Processing And Analysis B. Sleep Quality Indexes Sleep depth from the RR variability: respiratory variability is also associated with the sleep stage Low RR variability is associated with a deeper sleep stage Sleep depth is predicted with the standard deviation of the RR series (RRsd) in 20-min windows. Fig. 7. (a) Instantaneous RR. (b) RRsd computed in a 20-min sliding window. 26 Results A. Respiratory Signal Validation Fifteen volunteers between 50 and 90 kg are measured for 6 min a. Signals obtained from the pressure sensor array b. Signal obtained with the airflow sensor 27 Results A. Respiratory Signal Validation Pearson’s correlation coefficient, obtaining ρ = 0.904 T-test for pressure sensor array and airflow sensor signals are different is less than α = 0.001. Fig. 10. Airflow sensor signal and the pressure sensor signals have a positive linear correlation of ρ = 0.904 28 Results B. Evaluation of BM Detection Algorithm Fifteen volunteers evaluate the BM algorithm Three position changes : supine, lateral, and prone Compared with the known body position changes Se = 100% +P = 100% 29 Results C. Evaluation of Apnea Detection Algorithm Apnea detection algorithm, using a PSG and the implemented device simultaneously. Se = 71% and +P = 76% Fig. 11. Segment of a PSG record. The red marks represent the neurologist’s classification of an obstructive sleep apnea. Fig. 12. Segment of Fig. 11 obtained with the pressure sensors. The blue rectangular signal represents the apnea detection algorithm. 30 Results D. Evaluation of Automatic Signal Selection Algorithm Analyzed 485 segments processed by the algorithm In 86.6% of the cases, the algorithm agreed with at least one expert. 31 Results E. Analysis of Full-Night-Sleep Records Rec TB[min] BM SI>20 [min] SI<20 [min] Apenalike events V1n1 389.47 42 5 37 15 V1n2 369.35 28 7 21 16 V1n3 438.09 32 7 25 13 V2n1 300.77 28 5 23 56 V2n2 420.03 70 3 67 13 V3n1 415.02 97 3 94 35 V4n1 434.95 67 3 64 8 V5n1 553.95 63 9 54 34 V6n1 435.61 66 3 63 31 P1n1 537.42 151 4 147 288 32 Results E. Analysis of Full-Night-Sleep Records The worst case (p1n1) spent 87% of the time in short sleep intervals. The best case (v1n2) spent 37% of the time in short sleep intervals. Fig. 13 shows the cumulative frequency of the sleep interval duration. 33 Results E. Analysis of Full-Night-Sleep Records Number of sleep apneas provides information about SAHS Can be used as a parameter to estimate sleep quality Table I shows healthy volunteers have much lower apnea like events than the p1n1, who has 288 apnea like events 34 Conclusion This paper has presented a noninvasive monitoring device for sleep studies. Using simple sensor sheet Contain relevant information such as BMs and the respiratory signal Sleep parameters can be then obtained by processing those signals. This can prove to be a highly valuable tool to evaluate corrective actions to ensure the restful sleep of mine workers. 35 Thanks for your attention. 36