Infectious Process Principles of Immunology

Principles of Immunology Infectious Process 4/13/06 ”If we had no winter, the spring would not be so pleasant: if we did not sometimes taste of adversity, prosperity would not be so welcome” Anne Bradstreet Word/Terms List         Antigenemia Antigenic drift Antigenic shift Disease Infection Intoxication Normal flora Toxoid Infectious Process  Infectious Disease Triangle  Microbe/Agent  Host  Environmental conditions Categories of Microbes/Agents      Viruses Bacteria Fungi Parasites Prions Pathogenicity      Virulence factors Infectious Dose Route of infection Mode of transmission Microbe stability Host Defenses  Innate  Adaptive Things to remember  Host range  Infectious process as direct or indirect cause of disease  Infection vs. disease Pathogenicity      Virulence factors Infectious Dose Route of infection Mode of transmission Microbe stability Viral diseases       Obligate intracellular parasites Enveloped vs. non enveloped Latency Host range Tissue/cell specificity Antigenic changes Immunity to Viral diseases       Interferon NK cells Neutralizing Ab Secretory IgA C fixation Cell mediated immunity Bacterial diseases  Extracellular vs. intracellular  Toxins  Cell associated  Extracellular  Enzymes  Capsules  Fimbriae/pili Immunity to Bacterial Diseases     Antibodies Opsonization Phagocytes Cell-mediated immunity Fungal diseases  Opportunism  Capsules  Spores Immunity to Fungal diseases     Innate Normal flora Antibodies Cell mediated immunity Parasitic diseases     Large complex agents Range of diseases Environmental factors Immunity is complex

Infectious Process Principles of Immunology

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