KASPER/MOLTZAN QUIZ October 23, 2007 1) Dr. El-Gabalawy’s Connective Tissue Disease Dr. Targownik’s PUD Dr. Silver’s Psorias Reading Article: The Use of DXA Scans in the Diagnosis and Treatment of Osteoporosis Cystic Fibrosis (article) Which of the following is not associated with scleroderma a) telangiectasia b) small bowel bacterial overgrowth c) calcinosis d) increased risk of malignancy e) cardiac conduction defects Answer d 2) Which of the following investigations are rarely useful in the diagnosis and management of polymyositis a) MRI b) EMG c) muscle biopsy d) abdominal CT scanning e) pulmonary function tests Answer d 3) Which of the following is not an acceptable gastroprotective strategy in high-risk NSAID users a) PPIs b) H2-receptor antagonists c) Misoprostol d) COX-2 inhibitors e) Avoidance of NSAIDs Answer: b 4) Which of the following is TRUE: a) All dyspeptic patients who do not respond to a trial of empiric antisecretory therapy and HP eradication should undergo upper endoscopy b) A normal upper endoscopy may improve patient satisfaction in patients with non-ulcer dyspepsia c) Eradication of HP in HP+ patients is associated with a 50% absolute reduction in dyspepsia when compared to placebo d) PPIs are not effective for patients with non-ulcer dyspepsia e) The majority of patients with dyspeptic symptoms will have underlying peptic ulcer disease Answer: b 5) Which medication is containdicated in the treatment of psoriasis? a) cyclosporin b) soriatiane c) prednisone d) mycophenolate mofetil e) methotrexate Answer: c 6) True or false: Methotrexate alters the progression of joint disease in psoriasis Answer is false 7) Which of the following medications can exacerbate psoriasis a) metoprolol b) amoxicillin c) hydroxychloroquine d) a and c e) all of the above Answer is d 8) Which statement is false regarding the genetics of cystic fibrosis? a. Numerous mutations can effect the CFTR channel; all are on chromosome 7 b. The disease is inherited autosomal recessive (2 genes required) c. Carriers of one gene can express some phenotypic abnormalities d. Whites are more likely to acquire Cystic fibrosis then all other ethnicities Answer: C 9) Your convinced that your patient has Cystic Fibrosis. The Sweat Test is negative (can occur in 2% of patients). What other test can one do to make the diagnosis? a. 1) Answer: Genotype the chromosome 7 looking for mutations 10) The current medial survival age for patients with cystic fibrosis is? a. 18 years of age b. 25 years of age c. 35 years of age d. 50 years of age. Answer: C 11) Which of the following modalities is not recommended to be used in chronic cystic fibrosis therapy a. Nebulized Tobramycin every other month b. Azithromycin c. Oral Ciprofloxacin “ no stop” d. Inhaled Hypertonic Saline Answer: C 12) Which of the following is the optimum bone mineral density site for assessing a patients response to treatment? a. Total Hip b. Lumbar spine c. Total Body d. One third (33%) radius Answer: B 13) Which of the following BMD findings is sufficient for a diagnosis of Osteoporosis a. Both Spine or Hip T-Score between -1 and -2.5 b. Either Spine or hip T-score <-2.5