Biochemistry 2 (Medicine) Enrolment code: CBA200

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Unit details [CBA]
Biochemistry 2 (Medicine)
Enrolment code: CBA200
Offered: Hbt: (fy) ie sem 1 & 2
Special note: restricted to students enrolled in Medicine; taught by Discipline of Biochemistry
Unit description:
Provides medical students an understanding of: (a) structure and function of important
biological macromolecules, such as nucleic acids and proteins; (b) structure, function and
metabolism of amino acids, carbohydrates and lipids; (c) the integration and control of
metabolism, by hormonal and other means; (d) nutrition – roles of macro- and
micro-nutrients in health and disease, dietary guidelines, food composition; (e) basic
human genetics; (f) human molecular biology in health and disease; (g) metabolic and
genetic basis of disease states. Relevance to human health and disease is highlighted.
Staff: Dr DR Woodward (Coordinator), Dr SM Richards, Dr AK West, Dr AF Holloway
Unit weight: 20%
Teaching pattern: 59 hrs lectures; 13 hrs tutorials
Prereq: 1st year Medicine
Coreq: CHG210
Assess: 2-hr written paper at end of sem 1 (45%); 2-hr written paper at end of sem 2 (35%);
assessments during sem (20%)
Required: either
Meisenberg G & Simmons WH, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN 0815144105
or
Elliott WH & Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001, ISBN
0198700458
Recommend: Mann J & Truswell AS, Essentials of Human Nutrition, 2nd edn, OUP, Oxf, 2002,
ISBN 0198508611.
Courses: [M3J] [M3B] [M4B]
Faculty website: <www.healthsci.utas.edu.au>
Biochemistry (Pharmacy)
Enrolment code: CBA220
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University of Tasmania unit details for 2004 academic year
July 11, 2016, 18:55 PM, page –1
Unit details [CBA]
Offered: Hbt: (fy) ie sem 1 & 2
Unit description:
Gives pharmacy students an understanding of the following core areas of biochemistry
and molecular biology: (a) structure and function of important biological macromolecules,
such as nucleic acids and proteins; (b) structure, function and metabolism of amino acids,
carbohydrates and lipids; (c) the integration and control of metabolism, by hormonal and
other means; (d) nutrition – role of macro- and micro-nutrients in health and disease, food
composition, dietary guidelines; (e) basic human genetics; (f) human molecular biology in
health and disease; (g) metabolic and genetic basis of disease states. Relevance to human
health and disease is highlighted.
Staff: Dr AF Holloway, Dr SM Richards, Dr AK West, Dr DR Woodward (Coordinator)
Unit weight: 12.5%
Teaching pattern: 2–3x1-hr lectures weekly; 1-hr tutorial fortnightly
Prereq: KRA160, CHG101
Assess: 2-hr written paper at end of sem 1 (45%), 2-hr written paper at end of sem 2 (35%),
assessments during sem (20%)
Required: either
Meisenberg G & Simmons WH, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN 0815144105
or
Elliott WH & Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001, ISBN
0198700458
Recommend: Berg JM, Tymoczko JL & Stryer L, Biochemistry, 5th edn, Freeman, NY, 2002,
ISBN 0716746840
Murray RK, Granner DK, Mayes PA & Rodwell VW, Harper’s Biochemistry, 25th edn,
McGraw-Hill, NY, ISBN 0838536905
Courses: [M3F]
Faculty website: <www.healthsci.utas.edu.au>
Biochemistry (Agriculture)
Enrolment code: CBA235
Offered: Hbt: sem 1
Special note: restricted to Agricultural Science students; taught by Discipline of Biochemistry
Unit description:
Gives agricultural science students an introduction to: (a) structure and function of
important biological macromolecules, such as nucleic acids and proteins; (b) structure,
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University of Tasmania unit details for 2004 academic year
July 11, 2016, 18:55 PM, page –2
Unit details [CBA]
function and metabolism of amino acids, carbohydrates and lipids; (c) the integration and
control of metabolism, by hormonal and other means; (d) molecular biology; (e) nutrition.
Staff: Dr SM Richards, Dr DR Woodward (Coordinator)
Unit weight: 12.5%
Teaching pattern: 3x1-hr lectures weekly; 1-hr tutorial fortnightly
Prereq: KRA120 and KPZ162 and KZA160; students who do not have these prereqs should
consult unit coordinator
M.excl: may not be included in BAgSc with CBA230
Assess: 3-hr written paper at end of sem 1 (80%); assessments during sem (20%)
Required: Elliott WH & Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf,
2001, ISBN 0198700458
Recommend: Campbell MK & Farrell SO, Biochemistry, 4th edn, Thomson, 2003, ISBN:
0030348498
Gilbert HF, Basic Concepts in Biochemistry, 2nd edn, McGraw-Hill, NY, 2000, 0071356576
Courses: [S3A]
Faculty website: <www.healthsci.utas.edu.au>
Biochemistry: Metabolism & Nutrition
Enrolment code: CBA260
Offered: Hbt: sem 1
Special note: restricted to students enrolled in Science
Unit description:
Provides students with a broad introduction to metabolic and nutritional aspects of
biochemistry. Major topics include structure, function and metabolism of amino acids,
carbohydrates and lipids; the integration and control of metabolism, by hormonal and
other means; roles of selected nutrients in health and disease.
Students whose career aspirations are in the biomedical area are encouraged to include
both KZA150 and CHG100, as well as a first-year chemistry unit. Students whose career
aspirations are in the life sciences area are strongly encouraged to include both KZA151
and KPA150, as well as a first-year chemistry unit. (Please note that BSc rules do not allow
students to include both KZA150 and KPA150)
Students who do not have these prerequisites MAY be accepted after consultation with the
unit coordinator; for example, a student who has not done a first-year chemistry unit will
be considered if they have good marks in TCE Chemistry 12C, and have done one of the
prerequisite first-year biology units.
Staff: Dr AF Holloway, Dr SM Richards, Dr DR Woodward (Coordinator)
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University of Tasmania unit details for 2004 academic year
July 11, 2016, 18:55 PM, page –3
Unit details [CBA]
Unit weight: 12.5%
Teaching pattern: 2–3x1hr lectures, 3hrs lab weekly; 1-hr tutorial fortnightly
Prereq: ONE of (KRA110 Chemistry IA, KRA130 Chemistry IB) and ONE of (KZA150
Zoology IG, KPA150 Botany 1 G). See note above.
M.excl: this unit may NOT be included in BSc with CBA250 or CBA211
Assess: 3-hr written end-of-sem paper (80%), practicals (10%), tests during sem (10%)
Required: either
Elliott WH & Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001, ISBN
0198700458
or
Meisenberg G & Simmons YM, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN: 0815144105
Recommend: Mann J & Truswell AS, Essentials of Human Nutrition, 2nd edn, OUP, Oxf, 2002,
ISBN 0198508611
Courses: [S3G] [S3Gc1] [S3Gc2]
Faculty website: <www.healthsci.utas.edu.au>
Molecular Biology in Health & Disease
Enrolment code: CBA265
Offered: Hbt: sem 2
Special note: restricted to students enrolled in Science
Unit description:
Provides students with a broad introduction to molecular biology. The focus is primarily
on humans and other mammals, but most of the matters discussed apply to a much
broader range of species. Major topics include protein structure and function; DNA
structure, replication and transcription; protein synthesis; molecular biology of cancer;
genetics of human disease; DNA technology and its applications.
Students whose career aspirations are in the biomedical area are encouraged to include
both KZA150 and CHG100, as well as a first-year chemistry unit. Students whose career
aspirations are in the life sciences area are strongly encouraged to include both KZA151
and KPA150, as well as a first-year chemistry unit. (Please note that BSc rules do not allow
students to include both KZA150 and KPA150)
Students who do not have these prerequisites MAY be accepted after consultation with the
unit coordinator; for example, a student who has not done a first-year chemistry unit will
be considered if they have good marks in TCE Chemistry 12C, and have done one of the
prerequisite first-year biology units.
Staff: Dr AF Holloway, Dr SM Richards, Dr AK West, Dr DR Woodward (Coordinator)
________________________________________
University of Tasmania unit details for 2004 academic year
July 11, 2016, 18:55 PM, page –4
Unit details [CBA]
Unit weight: 12.5%
Teaching pattern: 2x1-hr lectures, 3 hrs lab weekly; 1-hr tutorial fortnightly
Prereq: ONE of (KRA110 Chemistry IA, KRA130 Chemistry IB) and ONE of (KZA150
Zoology IG, KPA150 Botany 1 G).
M.excl: This unit may not be included in BSc with CBA250 or CBA211
Assess: 3-hr written end-of-sem paper (90%), practicals, tests during sem (10%)
Required: either
Elliott WH & Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001, ISBN
0198700458
or
Meisenberg G & Simmons YM, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN: 0815144105
Recommend: Alberts B, Bray D, Johnson S, et al, Essential Cell Biology: An Introduction to
Molecular Biology of the Cell, Garland, NY, 1998, ISBN 0815329717
Courses: [S3G] [S3Gc1] [S3Gc2]
Faculty website: <www.healthsci.utas.edu.au>
Molecular Biochemistry: Techniques and Theory
Enrolment code: CBA327
Offered: Hbt: (fy) ie sem 1 & 2
Unit description:
Provides students with (i) an understanding and application of contemporary techniques
in protein biochemistry and molecular biology and (ii) an understanding of contemporary
developments in the areas of biochemistry relating to hormones, signal transduction and
molecular biology, particularly advanced related to genomics, transgenesis, cloning and
the Human Genome Project. Lectures cover: techniques in protein biochemistry and
molecular biology including isolation of organelles and membrane proteins; predictive
and actual structure of membrane proteins; measurement of membrane transport
processes; relationship of structure and function of membrane proteins; isolation and
purification of proteins and enzymes; proteomics; determination of kinetic constants of
enzymes; isolation of nucleic acids (DNA and RNA) from cells; in vitro manipulation of
nucleic acids, including PCR, site-directed mutagenesis, sequencing; cDNA libraries;
detection of sequences of defined composition and reintroduction of genes into bacterial
and eukaryotic cells; transformation, transfection, transgenic animals, microarrays,
bioinformatics, mammalian cloning by nuclear transfer; mechanisms of gene regulation;
programmed cell death in development and disease; hormonal control systems; signal
transduction. Practicals emphasise ‘hands-on’ experience with contemporary biochemical
techniques. The unit features a 10-week research project in the second semester.
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University of Tasmania unit details for 2004 academic year
July 11, 2016, 18:55 PM, page –5
Unit details [CBA]
Staff: Prof MG Clark, Dr AF Holloway, Dr SM Richards, Dr AK West
Unit weight: 50%
Teaching pattern: 3 lectures, 1-hr tutorial, 11 hrs practicals weekly
Prereq: CBA260 and CBA265
Assess: 2-hr written exam in June, 3-hr written exam in Nov, with 30% of final mark from
practical assignments and projects
Required: Alberts B, Johnson A, Lewis J, RaffM, Roberts K & Walter P, Molecular Biology of
the Cell, 4th edn. Garland NY, 2002, ISBN 0815340729
Recommend: Rapley R & Walker JM, Molecular Biomethods Handbook, Humana Press, Totowa
NJ, ISBN 0896035018
Courses: [S3G]
Faculty website: <www.healthsci.utas.edu.au>
Biochemistry for Biotechnology
Enrolment code: CBA330
Offered: Hbt: sem 1
Unit description:
Provides students with an understanding and application of contemporary techniques in
protein biochemistry and molecular biology central to biotechnology, eg, genomics,
transgenesis, cloning and the Human Genome project. Lectures cover: techniques in
protein biochemistry and molecular biology including isolation of organelles and
membrane proteins; predictive and actual structure of membrane proteins; measurement
of membrane transport processes; relationship of structure and function of membrane
proteins; isolation and purification of proteins and enzymes; proteomics; determination of
kinetic constants of enzymes; isolation of nucleic acids (DNA and RNA) from cells; in vitro
manipulation of nucleic acids, including PCR, site-directed mutagenesis, sequencing;
cDNA libraries; detection of sequences of defined composition and reintroduction of genes
into bacterial and eukaryotic cells; transformation, transfection; microarrays,
bioinformatics. Practicals emphasise ‘hands-on’ experience with contemporary
biochemical techniques.
Staff: Prof MG Clark, Dr AF Holloway, Dr AK West
Unit weight: 25%
Teaching pattern: 3 lectures, 1-hr tutorial, 11 hrs practicals weekly
Prereq: CBA260 and CBA265
M.excl: CBA327
Assess: 2-hr written exam in June (70%), practicals (30%)
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University of Tasmania unit details for 2004 academic year
July 11, 2016, 18:55 PM, page –6
Unit details [CBA]
Required: Alberts B, Johnson A, Lewis J, Raff M, Roberts K & Walter P, Molecular Biology of
the Cell, 4th edn, Garland NY, 2002, ISBN 0815340729
Recommend: Rapley R & Walker JM, Molecular Biomethods Handbook, Humana Press, Totowa
NJ, 1998, ISBN 0896035018
Other appropriate material will be indicated during the year.
Courses: [S3V]
Faculty website: <www.healthsci.utas.edu.au>
Advanced Biochemistry for Biotechnology
Enrolment code: CBA335
Offered: Hbt: sem 2
Unit description:
Provides students with in-depth coverage of selected topics relevant to biotechnology,
with a major emphasis on research laboratory experience. This unit is an excellent
preparation for students wishing to undertake a biomedically-oriented Honours degree.
Lectures cover: transgenic animals; mammalian cloning by nuclear transfer, human gene
therapy, stem cell technology; mechanisms of gene regulation; programmed cell death in
development and disease; hormonal control systems; signal transduction. The practical
component comprises a major research project which may be selected from any of the
research themes in the Discipline of Biochemistry.
Staff: Dr AF Holloway, Dr SM Richards, Dr AK West
Unit weight: 25%
Teaching pattern: 3 lectures, 1-hr tutorial, 11 hrs practicals weekly
Prereq: CBA260 and CBA265 and CBA330
M.excl: CBA327
Required: Alberts B, Johnson A, Lewis J, Raff M, Roberts K & Walter P, Molecular Biology of
the Cell, 4th edn, Garland NY, 2002, ISBN 0815340729
Recommend: Rapley R & Walker JM, Molecular Biomethods Handbook, Humana Press, Totowa
NJ, 1998, ISBN 0896035018
Other appropriate material will be indicated during the year.
Courses: [S3V]
Faculty website: <www.healthsci.utas.edu.au>
Biochemistry 4 (BSc Honours)
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University of Tasmania unit details for 2004 academic year
July 11, 2016, 18:55 PM, page –7
Unit details [CBA]
Enrolment code: CBA410
Offered: Hbt: (fy) ie sem 1 & 2
Special note: for Science students only
Unit description:
Aims: (a) to provide students with the opportunity to plan, execute, interpret and analyse
purposeful experiments, appropriate to their research project, and to communicate their
results; and to investigate and present on two areas, unrelated to their own research topic,
but representing important contemporary biochemical research in order to demonstrate
their skills in providing a condensed account of these areas of research and in
communicating their essential features in written and oral form; and (b) to provide a year’s
training in research, in order to give successful students a competitive edge in seeking
employment in biochemical research laboratories. The unit tests abilities which were
largely ignored in the earlier years. Students who excel in this Honours year are well
organised, plan carefully, are intensely motivated, are innovative thinkers, and express
their ideas and findings clearly.
Staff: Prof MG Clark, Dr AK West, Dr DR Woodward, Dr AF Holloway, Dr SM Richards
(Coordinator)
Unit weight: 100%
Prereq: BSc including CBA327 or equiv
Assess: the year’s performance is assessed from the research topic (thesis, 60%; project
seminar, 10%), and 2 assignments (10% for the essay and 10% for the reading topic
seminar presentation), supervisor’s assessment (10%). There are no written exams or
lectures, but students are expected to attend Discipline of Biochemistry seminars and those
of their own research group
Courses: [S4E]
Faculty website: <www.healthsci.utas.edu.au>
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University of Tasmania unit details for 2004 academic year
July 11, 2016, 18:55 PM, page –8
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