Biochemistry 2 (Medicine)

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CBA Unit Details as at 13th June, 2002
Biochemistry 2 (Medicine)
Enrolment code: CBA200
Offered: Hobart: semesters 1 & 2
Special note: restricted to students enrolled in Medicine; taught by Discipline of Biochemistry
Gives medical students an understanding of: (a) structure and function of important
biological macromolecules, such as nucleic acids and proteins; (b) structure, function and
metabolism of amino acids, carbohydrates and lipids; (c) the integration and control of
metabolism, by hormonal and other means; (d) nutrition – energy, roles of macro- and
micro-nutrients, dietary guidelines; (e) metabolic and genetic basis of disease states.
Relevance to human health and disease is highlighted.
Staff Dr SM Richards, Dr AK West, Dr DR Woodward (Coordinator)
Unit weight 25%
Teaching pattern 2–3x1-hr lectures weekly, 1-hr tutorial fortnightly focusing on integrative
problems; 3 to 4 hrs of self-directed learning projects fortnightly
Prerequisites 1st year Medicine
Corequisites CHG210, CJA212, CAM205
Assessment mode 3-hr written paper at end of sem 1; 3-hr written paper and a 10-min viva
voce at end of sem 2; self-directed learning projects will also be assessed
Required texts etc
either
Meisenberg G and Simmons WH, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN 0815144105
or
Elliott WH and Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001,
ISBN 0198700458
Recommended texts etc
Alberts B, Bray D, Johnson S, et al, Essential Cell Biology: An Introduction to Molecular Biology
of the Cell, Garland, NY, 1998, ISBN 0815329717
Brownie AC and Kernohan JC, Biochemistry: A Core Text with Self-Assessment, Churchill
Livingstone, Edin, 1999, ISBN 0443056935
Garrow JS, James WPT and Ralph A, Human Nutrition and Dietetics, 10th edn, Churchill
Livingstone, Edin, 2000, ISBN 0443056277
Marks DB, Marks AD and Smith CM, Basic Medical Biochemistry: A Clinical Approach,
Williams & Wilkins, Baltimore, 1996, ISBN 0683230107
Stryer L, Biochemistry, 4th edn, Freeman, NY, 1995, ISBN 0716720094
Mueller RF, Young ID, Emery’s Elements of Medical Genetics, 11th edn, Churchill
Livingstone, Edin, 2000, ISBN 044307125X
Nelson DL and Cox MM, Lehninger Principles of Biochemistry, 3rd edn, Worth, NY, 2000,
ISBN 1572599316
Courses [M3A] [M3B] [M4B]
Faculty website <http://www.healthsci.utas.edu.au/>
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University of Tasmania unit details
July 11, 2016, 18:39 PM, page –1
CBA Unit Details as at 13th June, 2002
Biochemistry (Pharmacy)
Enrolment code: CBA220
Offered: Hobart: semesters 1 & 2
Gives pharmacy students an understanding of the following core areas of biochemistry
and molecular biology: (a) structure and function of important biological macromolecules,
such as nucleic acids and proteins; (b) structure, function and metabolism of amino acids,
carbohydrates and lipids; (c) the integration and control of metabolism, by hormonal and
other means; (d) nutrition – energy, macro- and micro-nutrients, dietary guidelines; (e)
metabolic and genetic basis of disease states. Relevance to human health and disease is
highlighted.
Staff Dr SM Richards, Dr AK West, Dr DR Woodward (Coordinator)
Unit weight 12.5%
Teaching pattern 2–3x1-hr lectures weekly; 1-hr tutorial fortnightly
Prerequisites KRA160, CHG101
Assessment mode 3-hr written paper at end of sem 1, 2-hr written paper at end of sem 2
Required texts etc
either
Meisenberg G and Simmons WH, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN 0815144105
or
v
Recommended texts etc
Alberts B, Bray D, Johnson S, et al, Essential Cell Biology: An Introduction to Molecular Biology
of the Cell, Garland, NY, 1998, ISBN 0815329717
Brownie AC and Kernohan JC, Biochemistry: A Core Text with Self-Assessment, Churchill
Livingstone, Edin, 1999, ISBN 0443056935
Garrow JS, James WPT and Ralph A, Human Nutrition and Dietetics, 10th edn, Churchill
Livingstone, Edin, 2000, ISBN 0443056277
Marks DB, Marks AD and Smith CM, Basic Medical Biochemistry: A Clinical Approach,
Williams & Wilkins, Baltimore, 1996, ISBN 0683230107
Stryer L, Biochemistry, 4th edn, Freeman, NY, 1995, ISBN 0716720094
Mueller RF, Young ID, Emery’s Elements of Medical Genetics, 11th edn, Churchill
Livingstone, Edin, 2000, ISBN 044307125X
Nelson DL and Cox MM, Lehninger Principles of Biochemistry, 3rd edn, Worth, NY, 2000,
ISBN 1572599316
Courses [M3F]
Faculty website <http://www.healthsci.utas.edu.au/>
Biochemistry (Agriculture)
Enrolment code: CBA235
Offered: Hobart: semester 1
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University of Tasmania unit details
July 11, 2016, 18:39 PM, page –2
CBA Unit Details as at 13th June, 2002
Special note: restricted to Agricultural Science students; taught by Discipline of Biochemistry
Gives agricultural science students an introduction to: (a) structure and function of
important biological macromolecules, such as nucleic acids and proteins; (b) structure,
function and metabolism of amino acids, carbohydrates and lipids; (c) the integration and
control of metabolism, by hormonal and other means; (d) molecular biology; (e) nutrition.
Staff Dr SM Richards, Dr DR Woodward (Coordinator)
Unit weight 12.5%
Teaching pattern 3x1-hr lectures weekly; 1-hr tutorial fortnightly
Prerequisites KRA120 and KPZ120
Mutual exclusions may not be included in BAgSc with CBA230
Assessment mode 3-hr written paper at end of sem 1
Required texts etc
Elliott WH and Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001,
ISBN 0198700458
Recommended texts etc
Alberts B, Bray D, Johnson S, et al, Essential Cell Biology: An Introduction to Molecular Biology
of the Cell, Garland, NY, 1998, ISBN 0815329717
Campbell MK, Biochemistry, 3rd edn, Saunders, Philadelphia, 1999, ISBN 0030244269
Hanes BD and Hooper NM, Instant Notes Biochemistry, 2nd edn, Bios, Oxf, 2000, ISBN
1859961428
Stryer L, Biochemistry, 4th edn, Freeman, NY, 1995, ISBN 0716720094
Brownie AC and Kernohan JC, Biochemistry: A Core Text with Self-Assessment, Churchill
Livingstone, Edin, 1999, ISBN 0443056935
Nelson DL and Cox MM, Lehninger Principles of Biochemistry, 3rd edn, Worth, NY, 2000,
ISBN 1572599316
Courses [S3A]
Faculty website <http://www.healthsci.utas.edu.au/>
Biochemistry: Metabolism & Nutrition
Enrolment code: CBA260
Offered: Hobart: semester 1
Special note: restricted to students enrolled in Science
Provides students with a broad introduction to metabolic and nutritional aspects of
biochemistry. Major topics include structure, function and metabolism of amino acids,
carbohydrates and lipids; the integration and control of metabolism, by hormonal and
other means; roles of selected nutrients in health and disease.
Students whose career aspirations are in the biomedical area are encouraged to include
both KZA150 and CHG100, as well as a first-year chemistry unit. Students whose career
aspirations are in the life sciences area are strongly encouraged to include both KZAI 51
and KPA150, as well as a first-year chemistry unit. (Please note that BSc rules do not allow
students to include both KZA150 and KPA150)
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University of Tasmania unit details
July 11, 2016, 18:39 PM, page –3
CBA Unit Details as at 13th June, 2002
Students who do not have these prerequisites MAY be accepted after consultation with the
unit coordinator; for example, a student who has not done a first-year chemistry unit will
be considered if they have good marks in TCE Chemistry 12C, and have done one of the
prerequisite first-year biology units.
Staff Dr SM Richards, Dr DR Woodward (Coordinator)
Unit weight 12.5%
Teaching pattern 2–3x1hr lectures, 3hrs lab weekly; 1-hr tutorial fortnightly
Prerequisites ONE of (KRA110 Chemistry IA, KRA130 Chemistry IB) and ONE of (KZA150
Zoology IG, KPA150 Botany 1 G)
Mutual exclusions this unit may NOT be included in BSc with CBA250 or CBA211
Assessment mode 3-hr written end-of-sem paper (90%), practicals (10%)
Required texts etc
either
Elliott WH and Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001,
ISBN 0198700458
or
Meisenberg G and Simmons YM, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN: 0815144105
Recommended texts etc
All of the above, plus
Campbell MYC, Biochemistry, 3rd edn, Saunders, Philadelphia, 1999, ISBN: 0030244269
Garrow JS, James WPT and Ralph A, Human Nutrition and Dietetics, 10th edn, Churchill
Livingstone, Edin, 2000 ISBN: 0443056277
Stryer L, Biochemistry, 4th edn, Freeman, NY, 1995, ISBN: 0716720094
Wahl.qvist ML, Food and Nutrition: Australia Asia and the Pacific, Allen & Unwin, St
Leonards, 1997, ISBN: 1864482206
Brownie AC and Kernohan JC, Biochemistry: A Core Text with Self-Assessment, Churchill
Livingstone, Edin, 1999, ISBN: 0443056935
Nelson DL and Cox IM, Lehninger Principles of Biochemistry, 3nd edn, Worth, NY, 2000,
ISBN: 1572599316
Courses [S3G] [S3Gc1] [S3Gc2]
Faculty website <http://www.healthsci.utas.edu.au/>
Molecular Biology in Health & Disease
Enrolment code: CBA265
Offered: Hobart: semester 2
Special note: restricted to students enrolled in Science
Provides students with a broad introduction to molecular biology. The focus is primarily
on humans and other mammals, but most of the matters discussed apply to a much
broader range of species. Major topics include protein structure and function; DNA
structure, replication and transcription; protein synthesis; molecular biology of cancer;
genetics of human disease; DNA technology and its applications.
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University of Tasmania unit details
July 11, 2016, 18:39 PM, page –4
CBA Unit Details as at 13th June, 2002
Students whose career aspirations are in the biomedical area are encouraged to include
both KZA150 and CHG100, as well as a first-year chemistry unit. Students whose career
aspirations are in the life sciences area are strongly encouraged to include both KZA151
and KPAI 50, as well as a first1year chemistry unit. (Please note that BSc rules do not allow
students to include both KZA150 and KPA150)
Students who do not have these prerequisites MAY be accepted after consultation with the
unit coordinator; for example, a student who has not done a first-year chemistry unit will
be considered if they have good marks in TCE Chemistry 12C, and have done one of the
prerequisite first-year biology units.
Staff Dr SM Richards, Dr AK West, Dr DR Woodward (Coordinator)
Unit weight 12.5%
Teaching pattern 2x1-hr lectures, 3 hrs lab weekly; 1-hr tutorial fortnightly
Prerequisites ONE of (KRA110 Chemistry IA, KRA130 Chemistry IB) and ONE of (KZA150
Zoology IG, KPA150 Botany 1 G).
Mutual exclusions This unit may not be included in BSc with CBA250 or CBA211
Assessment mode 3-hr written end-of-sem paper (90%), practicals (10%)
Required texts etc
either
Elliott WH and Elliott DC, Biochemistry and Molecular Biology, 2nd edn, OUP, Oxf, 2001,
ISBN 0198700458
or
Meisenberg G and Simmons YM, Principles of Medical Biochemistry, Mosby, St Louis, 1998,
ISBN: 0815144105
Recommended texts etc
All of the above, plus
Campbell MYC, Biochemistry, 3rd edn, Saunders, Philadelphia, 1999, ISBN: 0030244269
Garrow JS, James WPT and Ralph A, Human Nutrition and Dietetics, 10th edn, Churchill
Livingstone, Edin, 2000 ISBN: 0443056277
Stryer L, Biochemistry, 4th edn, Freeman, NY, 1995, ISBN: 0716720094
Wahl.qvist ML, Food and Nutrition: Australia Asia and the Pacific, Allen & Unwin, St
Leonards, 1997, ISBN: 1864482206
Brownie AC and Kernohan JC, Biochemistry: A Core Text with Self-Assessment, Churchill
Livingstone, Edin, 1999, ISBN: 0443056935
Nelson DL and Cox IM, Lehninger Principles of Biochemistry, 3nd edn, Worth, NY, 2000,
ISBN: 1572599316
Courses [S3G] [S3Gc1] [S3Gc2]
Faculty website <http://www.healthsci.utas.edu.au/>
Molecular Biochemistry: Techniques and Theory
Enrolment code: CBA327
Offered: Hobart: semesters 1 & 2
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University of Tasmania unit details
July 11, 2016, 18:39 PM, page –5
CBA Unit Details as at 13th June, 2002
Provides students with (i) an understanding and application of contemporary techniques
in protein biochemistry and molecular biology and (ii) an understanding of contemporary
developments in the areas of biochemistry relating to hormones, signal transduction and
molecular biology, particularly advanced related to geneomics, transgenesis, cloning and
the Human Genome Project Lectures cover: techniques in protein biochemistry and
molecular biology including isolation of organelles and membrane proteins; measurement
of membrane transport processes; isolation and purification of proteins and enzymes;
determination of kinetic constants of enzymes; isolation of nucleic acids (DNA and RNA)
from cells; in vitro manipulation of nucleic acids; detection of sequences of defined
composition and reintroduction of genes into bacterial and eukaryotic cells;
transformation, transfection, transgenic animals, microarrays, bioninformatics, control of
gene expression; mechanisms of free radical action in cells and its consequences;
mammalian cloning by nuclear transfer; hormonal control systems; adrenergic control
systems; insulin and insulin-like growth factors; receptors; phosphoinositol turnover and
control of intracellular calcium; protein kinases; phosphoprotein phosphatases; covalent
modification. Practicals emphasise ‘hands-on’ experience with contemporary biochemical
techniques. The unit features a 10-week research project in the second semester.
Staff Prof MG Clark, Dr AK West
Unit weight 50%
Teaching pattern 3 lectures, 1-hr tutorial, 11 hrs practicals weekly
Prerequisites CBA250 or equiv
Assessment mode 2-hr written exam in June, 3-hr written exam in Nov, with 30% of final
mark from practical assignments and projects
Required texts etc
Rapley R, Walker JM, Molecular Biomethods Handbook, ISBN 0896035018
Recommended texts etc
Alberts B, Bray D, Lewis J, Raff M, Roberts K and Watson J, Molecular Biology of the Cell,
ISBN 0815316208
Lewin B, Genes VII, ISBN 0198792778
other appropriate material will be indicated during the year.
Courses [S3G]
Faculty website <http://www.healthsci.utas.edu.au/>
Biochemistry 4 (BSc Honours)
Enrolment code: CBA410
Offered: Hobart: semesters 1 & 2
Special note: for Science students only
Aims: (a) to provide students with the opportunity to plan, execute, interpret and analyse
purposeful experiments, appropriate to their research project, and to communicate their
results; and to investigate and present on two areas, unrelated to their own research topic,
but representing important contemporary biochemical research in order to demonstrate
their skills in providing a condensed account of these areas of research and in
communicating their essential features in written and oral form; and (b) to provide a year’s
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University of Tasmania unit details
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CBA Unit Details as at 13th June, 2002
training in research, in order to give successful students a competitive edge in seeking
employment in biochemical research laboratories. The unit tests abilities which were
largely ignored in the earlier years. Students who excel in this Honours year are well
organised, plan carefully, are intensely motivated, are innovative thinkers, and express
their ideas and findings clearly.
Staff Prof MG Clark, Dr AK West, Dr DR Woodward, Dr SM Richards (Coordinator)
Unit weight 100%
Prerequisites BSc including CBA327 or equiv
Assessment mode the year’s performance is assessed from the research topic (thesis, 60%;
project seminar, 10%), and 2 assignments (10% for the essay and 10% for the reading
topic seminar presentation), supervisor’s assessment (10%). There are no written
exams or additional lectures, but students are expected to attend Discipline of
Biochemistry seminars and those of their own research group
Courses [S4E]
Faculty website <http://www.healthsci.utas.edu.au/>
________________________________________
University of Tasmania unit details
July 11, 2016, 18:39 PM, page –7
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