Biochemistry Notes

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Biochemistry

Notes

Biochemistry

Biochemistry

Study of science that explores how properties of

CHEMICALS make life possible

Inorganic

Biochemistry

Compounds

 Compounds that do not contain carbon

Organic

Compounds

 Compounds that do contain carbon

 All living organisms are made of carbon

Biochemistry

Inorganic Compound

 Water

Most important inorganic compound for living organisms

Excellent solvent

Polar compound : opposite charges at each end of the molecule

High heat capacity : can absorb and release a lot of heat/energy before changing temperatures

Biochemistry

Organic Compounds

 Carbon

 Carbon forms the structural backbone of all organic molecules.

 Can bond with 4 other atoms OR can bond with other carbons to form long chains or rings .

Biochemistry

Organic Compounds

 Monomers

 Basic units that repeat over and over

 Polymer

 large compound formed from combinations of many monomers

Biochemistry

Four major kinds of polymers

(macromolecules)…

1)

Carbohydrates

2)

Lipids

3)

Proteins

4)

Nucleic acids

Biochemistry

1)Carbohydrates

 Contain C , H

2

, and O in the same ratio as in water

 Used for

 Basic Monomer

 Energy source (sugars and starches)

 Structural and cellular support

 Monosaccharide

Biochemistry

Monosaccharide

 Simple sugars

 Glucose and Fructose

 Same molecular formula

 C

6

H

12

O

6

Biochemistry

Disaccharide  Double sugar molecule

Polysaccharide

 Largest carbohydrate

 Starch : Stored food

(glucose)

 Sugar : Quick energy source

Biochemistry

2)Lipids

* Basic Monomer

 Fats , Oils , and

Waxes

 Contains C

2

, H

2

, and

O

2

 Insoluble in water

 Storage of energy

 Helps make up the cell membrane

 Glycerol + Fatty Acid

3)Proteins

Biochemistry

 Basic building material of all living things

 Examples : hair , nails , blood, muscle , skin

 Sources : egg whites , gelatin, meat

*Basic Monomer

 Amino Acid

Biochemistry

Amino Acids (aa)

 Each has a distinctive characteristic

 Same basic structure:

 Four groups attached to a central carbon atom

 Acid Group (COO)

 Amino Group (NH

3

)

 Hydrogen Atom (H + )

 “R-Group”  Determines the amino acid

Biochemistry

Amino Acids (aa)  20 different naturally occurring amino acids

 10 produced by the human body

 Held together by peptide bonds

 Polypeptide : 3 or more amino acids bonded together

Enzymes

Biochemistry

 They are proteins

 Like a key that fits into only one lock

 The lock is the substrate

 The key is the enzyme

 Active Site : Place where the enzyme and substrate bond

 Catalyst : Enzymes that speeds up a reaction

Biochemistry

4) Nucleic Acids

 Carry instructions for cellular activity

*Basic Monomer

 Nucleotide

Biochemistry

Deoxyribonucleic Acid  DNA

 Blueprint of instructions that get transmitted from generation to generation

 Found in the nucleus only (of eukaryotic cells)!!!

Biochemistry

Ribonucleic Acid  RNA

 Transfers and reads the instructions  then makes proteins

 Found in both the nucleus and the cytoplasm

Biochemistry

Three types of RNA:

 mRNA

 tRNA

 rRNA

 Messenger RNA

 Transfer RNA

 Ribosomal RNA

Biochemistry

There are four main  Adenine (A) bases in nucleic acids:  Guanine (G)

 Thymine (T)

 Cytosine (C)

But…in RNA, Thymine is replaced with…

 Uracil (U)

Biochemistry

 Now play the Jeopardy game (link on websites for Biochemistry webquest)

 Write out a summary of the question with the answer on your chart.

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