“My back has been bothering me….” William C. Scott, D.O. Louisiana State University Health Sciences Center Physical Medicine and Rehabilitation The Agenda • Case Presentation • Discuss pertinent physical exam findings. • Discuss three syndromes described in the literature. • Review a treatment plan for one of those syndromes which may involve physiatric, interventional, and Osteopathic techniques. Case Presentation • An 32 year old male “weekend warrior”, was playing flag football with his college buddies. • His team was down by 6 points and they needed a touchdown to win the game. • The patient was open for the reception and running towards the end zone when he awkwardly stepped with his left foot into a depression in the ground that was on the field. • He did not injure his ankle, but felt his outstretched left leg push up into his pelvis with an associated jolt of pain in his left low back that resolved temporarily several minutes later. • Over the next several days, the pain from his bumps and bruises during the game resolved, but a nagging focal left low back pain developed and persisted. • Two weeks later, he went to his primary physician with his dramatic and traumatic tale of the football tragedy What did the primary doc do? – Imaging – • X-ray of L/S –Spine read “mild degenerative changes of the Lumbosacral spine” • MRI or the L Spine showed, “bulging of L4/5 and L5/S1 discs without stenosis of the central canal or Neuronal foramen. Mild degenerative facet arthropathy of b/l L4/5 L5/S1 facets.” PMD DX? • PMD diagnosed the patient with “mechanical low back pain” • Prescribed – Motrin 600mg po 6h prn – Flexeril 10mg po qhs – Diazepam 5mg po q6h prn • The patient followed up with his PMD 4 weeks later with no significant relief of his symptoms. • He stated that he went to the ER on two occasions because of pain and received Demerol with short term relief. • The PMD is now referring this patient to you for his low back pain • He is obviously frustrated, and has missed several days of work already….. What do you want to do next? • TAKE A HISTORY! …Ask Questions – Describe the pain. – Started 2 months ago shortly after the football game – The pain is located over the left posterior iliac crest in the region of the Posterior Superior Iliac Spine (PSIS) – It feels focal and sharply tender pain to palpation – Now a 5/10 – Range of 4-8/10 , does not wake him from sleep – Worse with SB R>L, and a little worse with Flexion – Slightly better with supine position and Icy-hot What do you want to do next? • Ask more questions – Does it limit his function? • The patient tries to go to work, but has called in 14 sick days over the past 2 months • Hurts after walking a few blocks, standing, and sitting. – Any neurological changes? • No weakness • No numbness or tingling • No bowel or bladder incontinence What do you want to do next? • Ask more questions! – PMH – none – Surgeries – Denies – Allergies - None – Family history – Non-contributory What do you want to do next? • Ask more questions! – Social History • Denies any history of TOB, ETOH, or drug use/abuse • He is a machine worker for several years which requires him to lift 30-50lbs. He is happy with his job, likes his boss, and was recently promoted 6 months ago. • Happily married with two children. – Medications: • • • • Motrin 600mg 6-7 times a day Tylenol 650mg 8-10x a day Icy – hot Ben gay What do you want to do next? • Ask more questions! – Review of systems – • Unremarkable except for his back pain, which is getting worse while sitting in the chair and answering all these questions. So, what’s the differential diagnosis? • • • • • • • • • Discal and segmental degeneration May include facet arthropathy from osteoarthritis Myofascial, muscle spasm, or other soft-tissue injury/disorders Disc herniation - May include radiculopathy Radiographic spinal instability with possible fracture or spondylolisthesis May be due to trauma or degeneration Fracture of bony vertebral body or trijoint complex - May not reveal overt radiographic instability Spinal canal or lateral recess stenosis Primary of metastatic neoplasm, including myeloma Osseous, discal, or epidural infection Primary of metastatic neoplasm, including myeloma Inflammatory spondyloarthropathy • Referred pain • Gastrointestinal disorders • Genitourinary disorders, including nephrolithiasis, prostatitis, and pyelonephritis • Gynecologic disorders, including ectopic pregnancy and pelvic inflammatory disease • Abdominal aortic aneurysm • Hip pathology • Somatoform pain disorder • Psychiatric syndromes, including delusional pain • Drug seeking • Abusive relationships • Seeking disability or out-of-work status Physical Exam • 6’2 120lb male who is pleasant, cooperative, well groomed, a good historian, and appears in moderate distress and can’t seem to sit still secondary to pain. • No neurological findings were appreciated. – – – – No Atrophy Sensation intact to LT and PP Normal reflexes Strength of left hip flexion/extension limited by pain, otherwise strength testing is normal • The rest of the findings were unremarkable except for the musculoskeletal exam Surface Anatomy of the Sacrum and Pelvis Surface Anatomy of the Sacrum and Pelvis (Lateral) The postero-anterior lumbar spine X rays of 163 patients undergoing investigation for back pain were reviewed and the spinal level marking the intersection of a line joining the iliac crests was determined. This point coincided with the L4 spinous process or the L4-5 interspace in 78.6% • Anesthesia. 1996 Nov;51(11):1070-1. The reproducibility of the iliac crest as a marker of lumbar spine level. Render CA. Musculoskeletal Exam - Standing • - Left iliac crest was slightly HIGHER THAN the Right – Increased lumbar lordosis – Painful to palpation over LEFT medial iliac crest – Forward flexion was associated with some pain, but the ROM was not limited. – Pain with lateral bending towards the RIGHT – Standing flexion test was positive on the LEFT – PSIS was higher on the LEFT – Functional “S” curve of the spine (In group curves SB/Rot are to opposite sides!) • Lumbar Convex right (Lumbar is rotated RIGHT side bent LEFT) • Thoracic Convex left (Thoracic area is rotated LEFT side bent RIGHT) Musculoskeletal Exam - Supine – The ASIS is Lower on the Left – The pubic tubercle is Lower on the Left – Palpating the medial Malleoli, the left leg appeared longer • 3 test maneuvers cause low back pain on the left side – Straight leg raising – Pain is reported in the distribution of the Left iliac crest or slightly below – FABER – Causes low back pain on the left side – Hip flexion with the knees flexed through full ROM – causes pain on the left side – If root compression was suspected this test would be negative as the maneuver should relax the sciatic nerve Ligament Anatomy of the Sacrum and Pelvis Biomechanics of Pelvic Motion • Pelvic position and motion is influenced by the mechanics of the lower extremities • Pelvic motion/position may then influence spinal motion/position in part via the iliolumbar ligament because of it’s attachments to the L5 (L4) TP Biomechanics of Pelvic Motion • Physical exam of the Pelvis • Step 1 – – Standing flexion test – Side that moves the furthest is positive (your reference) • Step 2 – – Anterior landmarks – ASIS and Pubic Tubercle • Step 3 – – Posterior landmarks – PSIS – Foundations for Osteopathic Medicine, 1997 Biomechanics of Pelvic Motion and the Influence on Leg Length • Anterior pelvic tilt and inferior pelvic shear both result in a ipsilateral increase in functional leg length • Posterior tilt and superior shear both result in a ipsilateral decrease in leg length Functional Leg Length Discrepancy Influences Lumbar Mechanics • Functional Leg length discrepancy- – Results from muscular imbalance causing pelvic tilt – Reversible with balanced mechanics – Long leg side • Elevated iliac crest • Side bending of lumbar spine to the same side • Compensatory scoliosis at thoracic and cervical spine. Effect of Pelvic Obliquity on the Iliolumbar Ligament • Functional or anatomic leg length discrepancies may cause a stressed iliolumbar ligament • Calcification may be seen in one or both of these ligaments with longstanding postural strain – Wolfe’s Law – Calcium is laid down along lines of stress Wolf’s Law Exemplified by Chronic Iliolumbar Strain • Calcification of the iliolumbar ligament is an excellent example of structural change resulting from excessive functional demand. Iliolumbar Ligament Anatomy The development of the iliolumbar ligament and its anatomy and histology were studied in cadavers from the newborn to the ninth decade The structure was entirely muscular in the newborn and became ligamentous only from the second decade, being formed by metaplasia from fibers of the quadratus lumborum muscle • J Bone Joint Surg Br. 1986 Mar;68(2):197-200. The iliolumbar ligament. A study of its anatomy, development and clinical significance. Luk KD, Ho HC, Leong JC. Iliolumbar Ligament Anatomy By the third decade, the definitive ligament was well formed; degenerative changes were noted in older specimens The iliolumbar ligament may have an important role in maintaining lumbosacral stability in patients with lumbar disc degeneration, degenerative spondylolisthesis and pelvic obliquity secondary to neuromuscular scoliosis. J Bone Joint Surg Br. 1986 Mar;68(2):197-200. The iliolumbar ligament. A study of its anatomy, development and clinical significance. Luk KD, Ho HC, Leong JC. The Role of the Iliolumbar Ligament Iliolumbar ligament is important in restraining flexion, extension, and lateral bending of L5 on S1 The results indicated that the ligament was important in maintaining torsional stability of the lumbosacral junction • Spine. 1989 Jun;14(6):611-5. Torsional stability of the lumbosacral junction. Significance of the iliolumbar ligament. Chow DH, Luk KD, Leong JC, Woo CW. Biomechanical Functions of the Iliolumbar Ligament Five fresh cadaver specimens were used. In L5 spondylolysis, flexion and axial rotation of L5 on S1 are significantly regulated by the anterior and posterior bands of the iliolumbar ligaments The integrity of the ligament may determine the stability of the lumbosacral junction and the amount of forward slipping of the L5 vertebra. • J Orthop Sci. 2000;5(3):238-42. Biomechanical functions of the iliolumbar ligament in L5 spondylolysis. Aihara T, Takahashi K, Yamagata M Iliolumbar Ligament Anatomy The anatomy of the ligament and its orientation with respect to the sacroiliac joints were studied in 17 cadavers. Dissection showed the existence of several distinct parts of the iliolumbar ligament, among which is a sacroiliac part. This sacroiliac part originates on the sacrum and blends with the interosseous sacroiliac ligaments. Together with the ventral part of the iliolumbar ligament it inserts on the medial part of the iliac crest, separate from the interosseous sacroiliac ligaments. • The existence of this sacroiliac part of the iliolumbar ligament supports the assumption that the iliolumbar ligament has a direct restraining effect on movement in the sacroiliac joints. • J Anat. 2001 Oct;199(Pt 4):457-63.The sacroiliac part of the iliolumbar ligament.PoolGoudzwaard AL, Kleinrensink GJ, Snijders CJ, Entius C, Stoeckart R. Iliolumbar Ligament Anatomy found the ligament to consist of only two parts: the anterior part and the posterior part, both attaching to the L5 transverse process Both parts of the ligament were found to insert to the upper part of the iliac tuberosity, significantly lower than the iliac crest. also found no evidence of any ligament part attaching to the L4 transverse process • Arch Phys Med Rehabil. 1994 Nov;75(11):1245-6. The anatomy of the iliolumbar ligament. Hanson P, Sonesson B. Iliolumbar Ligament Anatomy Thirty iliolumbar ligaments of 15 volunteers were analyzed with magnetic resonance The portion of the iliolumbar ligament originating from the L-5 transverse process is made up of two bands (anterior and posterior). This posterior band is thinner than the anterior, with a smaller insertional base on the iliac crest, which explains its lesser resistance to torsional overloading and also explains the frequency of this painful syndrome. • Am J Phys Med Rehabil. 1996 Nov-Dec;75(6):451-5. Anatomy of the iliolumbar ligament: a review of its anatomy and a magnetic resonance study. Rucco V, Basadonna PT, Gasparini D. Iliolumbar Ligament Anatomy The insertion manner of iliolumbar ligament posterior band in the iliac crest allows us to confirm the possibility of existence of the lumbar painful syndrome termed iliolumbar syndrome and confirms the possibility of examining its insertional site manually Am J Phys Med Rehabil. 1996 Nov-Dec;75(6):451-5. Anatomy of the iliolumbar ligament: a review of its anatomy and a magnetic resonance study. Rucco V, Basadonna PT, Gasparini D. Iliolumbar Anatomy Affecting Disc Degeneration Dissected 25 male and 27 female cadavers and measured the length and cross-sectional area of the anterior and posterior bands of the iliolumbar ligament If the iliolumbar ligaments (especially the posterior band of the ligament) are short and have a large cross-sectional area – 1) the lumbosacral junction can be stabilized by the ligaments, with the L5-S1 disc being protected from degeneration • The L4-L5 disc may be prone to degeneration. – Spine. 2002 Jul 15;27(14):1499-503. Does the morphology of the iliolumbar ligament affect lumbosacral disc degeneration? Aihara T, Takahashi K, Ono Y, Moriya H. Iliolumbar Ligament Causing Back Pain The iliolumbar ligament appears to be a major stabilizing component between the vertebral spine and the pelvis It is the weakest component of the multifidus triangle There is increased susceptibility to injury due to its angulated attachment It is a primary inhibitor of excess sacral flexion It is a highly innervated nociceptive tissue It plays an increased role with progressive disc degeneration. • Med Hypotheses. 1996 Jun;46(6):511-5.The role of the iliolumbar ligament in low back pain. Sims JA, Moorman SJ. Iliolumbar Syndrome • First Described by Gerald G. Hirschberg, MD • “In our experience the chronic iliolumbar syndrome is the most common cause of permanent or recurrent low back disability” • Iliolumbar Syndrome As a Common Cause of Low Back Pain: Diagnosis and Prognosis Hirschberg G., Arch Phys Med Rehabil; Vol 60, pp 415-419. Sept 1979 Research in Iliolumbar Syndrome The authors studied the files of 440 patients with low back pain over a period of 8 years The constant absence of signs of lumbar sciatica led them to study the etiology of such a pain Pain in the ilio-lumbar ligament is due to the development of a syndesmo-periostitis (syndesmos = ligament) from the ligaments continual traction on the postero-medial iliac crest Iliolumbar syndrome. A syndesmoperiostitis of the iliac crest. Clinical, radiologic and therapeutic summary. Diagnosis with lumbar sciatica. 440 cases]Rev Rhum Mal Osteoartic. 1982 Oct;49(10):6938. Broudeur P, Larroque CH, Passeron R, Pellegrino J. British Literature In 100 patients with mainly chronic low back pain (LBP) signs and symptoms were evaluated prospectively Characterized by 'typical local tenderness' and associated with specific clinical features Iliolumbar Syndrome occurred in 43% of the patients Br J Rheumatol. 1990 Oct;29(5):354-7. Clinical epidemiological study in low back pain. Description of two clinical syndromes. Collee G, Dijkmans BA More Foreign Literature • Domljan Z, Curkovic The iliolumbar syndrome] Lijec Vjesn. 1983 Jul-Aug;105(7-8):287-9. Croatian. • Schapira D. [The iliolumbar syndrome] Harefuah. 1987 Dec 1;113(11):352-4. Review. Hebrew. • Broadhurst N. The iliolumbar ligament syndrome. Aust Fam Physician. 1989 May;18(5):522. Onset Mechanism of Iliolumbar Syndrome • Ex #1 – Lifting Accidents – frequently present with acutely disabling pain, unable to walk or move • Ex # 2 – Patients are immediately aware of a pull or snap in the low back and then the pain remits, and later it reoccurs more or less severe • Ex #3 – Patients may have no immediate awareness of a back injury, and then gradually increases in severity. – falls or rear end collisions – Ex #4 • The patient does not recall any injury and the pain starts insidiously • Iliolumbar Syndrome As a Common Cause of Low Back Pain: Diagnosis and Prognosis Hirschberg G., Arch Phys Med Rehabil; Vol 60, pp 415-419. Sept 1979 Symptoms of Iliolumbar Syndrome • Pain localized at the posterior portion of one iliac crest. • The patient is typically able to put their finger on the exact site of the low back pain • At times patients present with pain across the iliolumbar area bilaterally • Iliolumbar Syndrome As a Common Cause of Low Back Pain: Diagnosis and Prognosis Hirschberg G., Arch Phys Med Rehabil; Vol 60, pp 415-419. Sept 1979 Symptoms of Iliolumbar Syndrome • Pain may be extremely severe or a constant dull ache aggravated by activity • Some complain of pain with prolonged standing or sitting • Pain may radiate into the hip, groin, anterior, lateral, or posterior aspects of the thigh • Iliolumbar Syndrome As a Common Cause of Low Back Pain: Diagnosis and Prognosis Hirschberg G., Arch Phys Med Rehabil; Vol 60, pp 415-419. Sept 1979 Findings of Iliolumbar Syndrome • On exam while standing – – – – One iliac crest is frequently higher than the other A discrepancy of leg length may be seen Usually, the painful crest is the higher one Forward flexion is usually associated with some pain, but frequently the ROM is not limited. – Pain with lateral bending. • Usually, the pain is worse when laterally bending away from the painful side • Iliolumbar Syndrome As a Common Cause of Low Back Pain: Diagnosis and Prognosis Hirschberg G., Arch Phys Med Rehabil; Vol 60, pp 415-419. Sept 1979 Findings of Iliolumbar Syndrome • On exam in the supine position – 3 test maneuvers cause low back pain on the involved side – Straight leg raising – Pain is reported in the distribution of the iliac crest or slightly below – FABER – Causes low back pain on involved side – Hip flexion with the knees flexed through full ROM – causes pain on involved side – If root compression was suspected this test would be negative as the maneuver should relax the sciatic nerve • Iliolumbar Syndrome As a Common Cause of Low Back Pain: Diagnosis and Prognosis Hirschberg G., Arch Phys Med Rehabil; Vol 60, pp 415-419. Sept 1979 Findings of Iliolumbar Syndrome • Examination in the prone position – The most typical sign is tenderness to palpation of the iliac crest on the involved side – Tenderness is usually limited to the insertion of the iliolumbar ligament, but at times may be across the whole length of the crest with maximum tenderness in the posterior third • Iliolumbar Syndrome As a Common Cause of Low Back Pain: Diagnosis and Prognosis Hirschberg G., Arch Phys Med Rehabil; Vol 60, pp 415-419. Sept 1979 X-ray in Iliolumbar Syndrome • X-rays of the lumbosacral spine are frequently normal or show degenerative changes of the lumbar spine. – Iliolumbar Syndrome As a Common Cause of Low Back Pain: Diagnosis and Prognosis Hirschberg G., Arch Phys Med Rehabil; Vol 60, pp 415-419. Sept 1979 Imaging of the Iliolumbar Ligament Studied MRI of iliolumbar ligaments in cadavers • Routine imaging of the intervertebral disc region as well as contiguous axial imaging of the spine depicted only limited segments of the iliolumbar ligament. • Only images of the iliolumbar ligament obtained through computer reformatting of three-dimensional volume averaging from L3 to the sacral ala correlated with the ligament's structural characteristics. – The Iliolumbar Ligament: Three-Dimensional Volume Imaging and Computer Reformatting by Magnetic Resonance: A Technical Note. Spine. 25(9):1098-1103, May 1, 2000. Hartford, James M. MD *; McCullen, Geoffrey M. MD +; Harris, Robert MD ++; Brown, Cameron C. MD [S] Iliolumbar Syndrome – Injection to Confirm the Diagnosis • X-rays after infiltration of the iliac crest with a few cc’s of lidocaine and radiopaque material showed it spread all along the iliolumbar ligament from the iliac crest to the transverse process of L-4 and L5. This resulted in relief of all signs and symptoms. • Iliolumbar Syndrome As a Common Cause of Low Back Pain: Diagnosis and Prognosis Hirschberg G., Arch Phys Med Rehabil; Vol 60, pp 415-419. Sept 1979 Treatment of Iliolumbar Syndrome • Not many studies on this specifically. • Based on what has been presented, treatment should involve: – A) Patient education on back saving practices, i.e. proper lifting technique, work modification, HEP, smoking cessation etc. – B) Relief of symptoms with NSAIDS, PT, modalities, interventional techniques, RF?. – C) Restoration of body mechanics • Address muscle imbalance between anterior and posterior musculature • Treat pelvic obliquity Treatment of Iliolumbar Syndrome Thirty patients with low-back pain of at least one month's duration were included in a double-blind controlled study and treated with either methylprednisolone mixed with lidocaine or isotonic saline, injected at the site of the iliolumbar ligament. In the methylprednisolone group, significant decreases in pain score and in patients' self-assessments were found. The range of spinal flexion did not undergo any significant change. No significant changes were found in the control group • Scand J Rheumatol. 1985;14(4):343-5. Injection of steroids and local anesthetics as therapy for low-back pain. Sonne M, Christensen K, Hansen SE, Jensen EM. Osteopathic Manipulation for Pelvic Obliquity • Rationale based on anatomy supports a restoration of a level pelvis to decrease strain on the iliolumbar ligament. • Treatment of L4 and L5 rotation and SB along with lumbar and thoracic compensatory curves should also be addressed. • The following techniques are helpful – Muscle Energy – High Velocity Low Amplitude Muscle Energy-How Does It Work? • A patient provides a contraction in a already tight muscle, acting against equal resistance provided by the physician, results in pulling on the Golgi tendon receptors producing a reflex relaxation of that muscle’s extrafusal muscle mass through the Golgi tendon reflex mechanism. • When the patient is completely relaxed, the operator advances the joint to the new restrictive barrier. At each new length, the Golgi receptor is stretched again and the muscle’s length is again increased. Muscle Energy Schematic Research in Osteopathy • OMT in low back pain appears to decrease the need for other co-treatment modalities such as medications – Anderson GB, Lucente T, Davis AM, Kappler RE, Lipton JA, Leurgans S. A comparison of osteopathic spinal manipulation with standard care for patients with low back pain. N Engl J Med.1999; 341:1426 -1431. – Williams NH, Wilkinson C, Russell I, et al. Randomized osteopathic manipulation study (ROMANS): pragmatic trial for spinal pain in primary care. Fam Pract.2003; 20:662 -669. – Licciardone JC, Stoll ST, Fulda KG, Russo DP, Siu J, WinnW, et al. Osteopathic manipulative treatment for chronic low back pain: a randomized controlled trial. Spine.2003; 28:1355 -1362 • “In the absence of consensus as to the etiology of nonspecific low back pain, it seems important for us to rely on clinical data to identify specific syndromes” • Iliolumbar Syndrome As a Common Cause of Low Back Pain: Diagnosis and Prognosis Hirschberg G., Arch Phys Med Rehabil; Vol 60, pp 415-419. Sept 1979 A Word About Iliac Crest Syndrome • Pain is usually of sudden onset after repeated flexion/extension activity. • Characterized by an extremely discrete localized area of pain without radiation. No associated thoracolumbar pain. – Location corresponds to the lateral border of the origins of the gluteus maximus and sacrospinalis Spine 1983 vol 8, The iliac crest syndrome JT Fairbank • Magnetic resonance imaging is normal in the iliac crest pain syndrome – J Rheumatol. 1993 Feb;20(2):407-8. Magnetic resonance imaging is normal in the iliac crest pain syndrome. Reynierse M, Dijkmans BA, Collee G, Bloem JL, Kroon HM. A Word on Iliac Crest Syndrome Prospectively studied 204 consecutive patients with LBP from a general practice (n = 40), an occupational health service (n = 124) and a rheumatology clinic (n = 40). ICPS was found in 53%, 33% and 58%, respectively (41% of the total group). Typical was local tenderness over the medial part of the iliac crest • J Rheumatol. 1991 Jul;18(7):1064-7. Iliac crest pain syndrome in low back pain: frequency and features. Collee G, Dijkmans BA, Vandenbroucke JP, Cats A. Treatment of Iliac Crest Pain Syndrome 41 patients with the iliac crest pain syndrome (ICPS), In a 2-week, double blind, randomized study, the authors compared the efficacy of a single local injection of 5 ml lidocaine, 0.5% with 5 ml isotonic saline Effect of a local injection with lidocaine - 53% improved, versus 8% with saline • J Rheumatol. 1991 Jul;18(7):1060-3. Iliac crest pain syndrome in low back pain. A double blind, randomized study of local injection therapy. Jollee G, Dijkmans BA, Vandenbroucke JP, Cats A. A Word on Cluneal Nerve Entrapment The authors describe a case of longstanding low back pain related to entrapment neuropathy of the L1-L2 dorsal ramus (innervates posterior somatic structures) over the iliac crest. 3 local anesthetic pain blocks (at the trigger point, 7 cm left of the L5 spine process and just above the iliac crest) were successful for 3 weeks each. A surgical procedure was then performed which corrected patient stricture of a voluminous dorsal ramus within a rigid osteofibrous orifice between the upper rim of the iliac crest and the thoracolumbar fascia Pain decreased dramatically the same day and disappeared completely within less than a week. • J Rheumatol. 1996 Dec;23(12):2179-81. A potentially under recognized and treatable cause of chronic back pain: entrapment neuropathy of the cluneal nerves. Berthelot JM, Delecrin J, Maugars Y, Caillon F, Prost A. A Word About Maigne Syndrome The diagnosis is made on pure clinical grounds Classic signs are: a positive "iliac-crest point" test, a positive skinrolling test, localized tenderness over a certain spinous process at the thoracolumbar junction and tenderness over the involved apophyseal joint. The diagnosis is confirmed by a periapophyseal joint block using a local anesthetic • Arch Phys Med Rehabil. 1980 Sep;61(9):389-95.Low back pain of thoracolumbar origin. Maigne R. A Word About Maigne Syndrome Of 350 patients seen in a back pain clinic, 40% were found to have pain of thoracolumbar origin Treatment included manipulation, infiltration with corticosteroids, electrocoagulation and/or surgical denervation of the involved apophyseal joint. Arch Phys Med Rehabil. 1980 Sep;61(9):389-95.Low back pain of thoracolumbar origin. Maigne R. A Word About Maigne Syndrome The authors performed 37 dissections The authors claim the iliac insertion of the iliolumbar ligament is inaccessible to palpation, being shielded by the iliac crest The dorsal rami of L1 or L2 nerve roots, however, cross the crest at 7 cm from the midline, and this distance closely correlates with the dorsal projection of the iliolumbar ligament insertion Arch Phys Med Rehabil. 1991 Sep;72(10):734-7.Trigger point of the posterior iliac crest: painful iliolumbar ligament insertion or cutaneous dorsal ramus pain? An anatomic study. Maigne JY, Maigne R. A Word About Maigne Syndrome In two of the 37 dissections performed, some rami were found to be narrowed as they crossed through an osteofibrous orifice over the crest, thus being susceptible to an entrapment neuropathy The authors conclude that the trigger point sometimes localized over the iliac crest at 7 cm from the midline likely corresponds to elicited pain from a cutaneous dorsal ramus originating from the thoracolumbar junction rather than from the iliac insertion of the iliolumbar ligament. Arch Phys Med Rehabil. 1991 Sep;72(10):734-7.Trigger point of the posterior iliac crest: painful iliolumbar ligament insertion or cutaneous dorsal ramus pain? An anatomic study. Maigne JY, Maigne R. • “…the question is whether that pain is the cause, the consequence, or simply one of the features, of the dysfunction” • Robert Maigne Conclusion • The diagnosis of “Mechanical Low Back Pain” may be too vague given the surfacing of specific back pain etiology. • While pain generators may be identified and important to treat, broader biomechanical factors must also be addressed to aim for a potentially sustained therapeutic solution. • Studies have yet to link and fully explain the complex interrelationships of biomechanical models and musculoskeletal pathology as it relates to onset of various pain generators. • More research is needed