ANNUAL REPORT 2012 Name of Department: LIFE SCIENCES The University of Calicut, while submitting the developmental proposal to the UGC, put a proposal to establish a new department of Life Sciences to teach Physiology, Biochemistry and Microbiology in an integrated manner during the fifth plan period. The UGC review committee strongly recommended for the same and consequently this department came into being, towards the fag end of the fifth plan period in February 1978. The department was started with three Readers, one each in Physiology, Biochemistry and Microbiology and has grown into eight in terms of staff strength. Initially M.Sc. Courses in Microbiology and Physiology were offered. Msc in Life Sciences was run for a few years and, on recognizing the significance, specialisation in Physiology, Biochemistry and Microbiology were introduced subsequently. At present, along with the three M.Sc. Courses, M. Phil. is also offered in these subjects. Students getting M.Sc. Degree in these areas from this Department have been finding employment and research placements in academic/professional institutions such as Medical colleges, apex institutes such as the Defence Institute of Physiology and Allied Sciences, Institute of Nuclear Medicine and Allied Sciences, National Institute of Mental Health and Neurosciences, All India Institute of Medical Sciences as well as Pharmaceutical industries. Also considerable number of our students had obtained admission to M.Tech. through entrance examination, after their MSc. Many students of this department have attained their Ph.D degrees from reputed Universities and Research Institutes within the country and abroad. At a time, 6 of them had been working in various Institutes of Germany in subjects like Neurophysiology, Molecular Biology and Biochemistry, and all are engaged now in Post-doctoral research work in those Institutes. Besides teaching M.Sc. Courses, the department also embarked on research training at Ph.D level from the very inception, in all the three areas. Till now, 22 candidates have taken Ph.D from this department and 16 more are working for the doctoral degree under various research guides, some of whom are teachers in the nearby Institutes like Medical College, Amala Cancer Centre, Trichur etc, but having guideship through this department. One unique feature of the Ph.D training in this department has been the registrations sought for Ph.D by the members of the faculty in Medical colleges after taking M.D degree in medicine, surgery, pathology etc. Five candidates have been awarded Ph.D in Medical faculty so far and four more are working for the same. The department is now set to develop the infrastructure in cell culture, protein chemistry and molecular biology in accordance to the demands of the day. For, that we are planning to submit project proposals to various funding agencies in this regard. 1. Divisions in the Department, if any Microbiology, Biochemistry and Human Physiology 2. Faculty in the Department Nos Name Designati on 1 Professor Dr. K. Fathimathu Zuhara.K Gender Specialization SC/ST/OBC Female Medical Microbiology & Immunology OBC 2 Dr. B.S Harikumaran Thampi Reader ( HOD) Male Nutritional Biochemistry FC 3 Dr. E Sreekumaran Reader Male Electrophysiology and Stem cells. SC 4 Dr. Denoj Sebastian Asst.Prof. Male Animal Cell culture & Virus Culture, Bioinformatics, Bioremediation FC 5 Mr.. Emmanuel Simon Asst.Prof 6 Dr. D Gayathri Asst.Prof Devi Male Cancer biology &LC Drug design. Female Cancer Biology OBC 3. Brief account of the major activities during 2012PG Results have been published in time , Registered a total pass in the fourth semester examination. Monthly seminars by research scholars. Conducted Prof. V K Sasidharan award function and lecture. Participation and presentation of posters by Faculties in International and National Seminars. 4. Details of the Externally Funded Projects - Two Name of PI Title Prof.K F Zuhara Amount Duratio Date of Closure Objectives and n commenci date Relevance ng Isolation, Rs. 2 years screening and 1,45,000 optimisation /-. of some microorganis ms for fibrinolytic enzymes. 01/02/11 01/02/ The topic is of high 13 relevance because fibrinolytic enzymes have significant role in treating cardiovascular diseases. Currently used agents against thrombosis possess adverse side effects and also they are expensive. Different fibrinolytic microorganisms were isolated from various sources in this study. Optimization of the organisms were done to develop better and efficient production of the enzyme. Dr. E Potential of Two Sreekumara stem cell lakhs n therapy for diabetes: a study on Wistar albino rats. Two years 01/07/12 30/06/1 Stem cell 4 research is a very relevant field in these days as it can be an effective treatment in almost all diseases. Here, the incorporation of stem cells for diabetes treatment is being studied. 5. Current Status –Ongoing, Completed, Forwarded for grant Ongoing - Two Projects, Forwarded For grant – One Dr. E Sreekumara n ( PI) & Co Investigat or Dr B S Harikumara n Thampi Antihyper 13 glycaemic lakhs effects of some Ayurvedic preparation: A prospective study on rats. 36 months Ayurveda has relevance in Kerala as it being the place of origin. It has been seen that there is some antihyperglycaemi c effect of some ayurvedic formulations, so the method of its action is to be studied. 6. Publications of the Faculty Members and Research Scholars (please separately in the below format) 1. RESEARCH PAPERS IN INTERNATIONAL JOURNALS S Name and Short Title Co Journal Date of l. Designatio author if Publicati N n any on o 1 Dr. 1.Chromatographic K.M. Asian 2012, 2 Fathimathu profiling using RP- Thara Journal of (1):54-57. Zuhara K. HPLC and Plant Estimation of Science and Biochemical Research. Parameters of Saussurea lappa. European 2.Comprehensive K.M. Journal of In-vitro Thara Experimenta 2012, 2 pharmacological l Biology. (2):417activities of different 420 extracts of Saussurea lappa. Journal of 2012,5(3), 3.Confertin, K.M. Pharmacy 1559myricetin and Thara Research. 1564. diaminobutryic acid are found to be present in the methanol extract of Saussurea lappa and it showed antiproliferative effect on DLA cell lines and inhibitory effect on the growth of microbial organisms. 4.Biochemical analysis and biological activities of Embelia ribes. K.M. Thara International Journal of Applied Biochemistr y and provide Impact Factor 0.2 0.2 1.2 ACCEPT ED TO 0.5 PUBLIS H IN February 2 1.Management of Dr. E. Beenar Sreekuma elevated liver ani K enzymes in ran geriatric diabetes by yogic practice 2.Yogic Practice and Diabetes Mellitus in Geriatric Patients Sl. No Beenara ni K Biotechnolo gy. -2013. Internationa l Multidiscipl inary Research Journal. Vol 2, No 8 (2012) Internation al Journal of Yoga (In press) 2. RESEARCH PAPERS IN NATIONAL JOURNALS - Nil Name and Short Co Journal Date Designation Title author Publication if any 3. BOOKS/EDITED VOLUMES - Nil Sl. Name and Short Publisher No Designation Title ISSN: 22316302 Availabl e Online: http://irjs .info/ Date Publication of Impact Factor of Impact Factor Note: Average Impact Factor of the Dept: (AIF= Sum of Impact Factors of all publications by all faculty members/Total No of Publications) 7. Articles in Popular Weekly/News Papers -Nil 8. Papers Presented 1. Inter National Conferences- Nil 2. National Conferences ( Posters ) - 3 Nos 9. 10. Extension Lectures Delivered by Faculty Members - 5 11. Academic Awards Conferred on Faculty - Nil 12. Ph.D Awarded during 2012 - Nil 13. Details of Research Guides re inducted in the Dept. Nil Details of research guides and students Sl No 1. Name of Name of Research Student Guide Dr. 1.Thara Fathimathu K.M. Zuhara K. (parttime) Title of Ph.D 1. Screening of some Indian Medicinal plants for Antimicrobial activity. 2.Reshma C.V. (full-time) 2.Isolation, creening and optimisation of some m icroorganisms 3.Deepa for fibrinolytic K.S. enzymes. (full-time) 3.Screening, isolation and Male /Fem ale F F Year of Status Registerati on Completed continuing ” F 4.Shiji Thomas (parttime) optimisation of oleaginous microorganisms for single cell oil. 4. A study on the 5.N.S.Ravi synergistic effect chandran of some (partantimicrobial time) agents. 2 Dr E Beena Sreekumaran Rani, K Greeshma C Deepthi Mahesan Rahmath A Effect antioxdants Diabetes mellitus. of F in Application of F stem cells for the treatment of some induced disorders. Studies on the F therapeutic properties of some herbal formulations on peripheral neuropathy. F Comparative study of the effect of selected herbs, biomolecules and modern medicines in dementia induced rats F “ M “ Re registered CDC/B3/155 /2009 dated 29/04/2009 . Compeleted Continuing 01/07/09 “ 16/06/10 “ 16/06/10 Seena T P Ahamed Shahal M Sreejesh P G F Antihyperglycemic effect of some ayurvedic preparations: A prospective study on rats. Role of M selected herbal preparations in the management of parkinsonism in rats. M Detrimental effect of food additives in different parts of brain and the antidotal effect of “ 16/06/10 2012 “ 2012 “ Myristica fragrans and Annona muricata 3 3 Dr Harikumaran Thampi compared to modern medicine. 1 Mrs. A study on F Anshida, Dietary KA Polyphenols. 2, Mr, Studies on M Kishore Bioactive MH compunds from marine organisms Dr Denoj1, Mr. BijeshExploitation ofM Sebastian K genetically modified microorganisms for pectinase production from agro-waste 2012 “ 2012 “ 2012 “ 2. Production of M Shinilkuma improved amylase rS from agro-waste using genetically modified bacteria 3. C.P. Improvement of F Sreena biocatalytic efficacy of cellulases from indigenous microorganisms for bioconversion of agro-waste 2012 2012 “ “ 14. External Scholarships/Fellowships awarded to Scholars in the Dept. Nil 15. Contributions of the Faculty- Invited Lectures in ASC, University of Calicut By Dr.E Sreekumaran and Dr Denoj Sebastian Seminars/Workshops/Conferences/ organized in the Dept 1. International Nil 2. National 1 Prof. V K Sasidharan endowment lecture By Dr Retna Raj, Asso.Prof NIIT Calicut. 16. Patents Granted/Filled Nil ------------------------