LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
B.Sc. DEGREE EXAMINATION – ADVANCED ZOOLOGY & BIOTECH.
FIFTH SEMESTER – APRIL 2008
AZ 5501 / ZO 5501 - GENETICS
Date : 28/04/2008
Time : 1:00 - 4:00
Dept. No.
DE 39
Max. : 100 Marks
PART – A
Answer ALL:
(10 x 2 = 20)
1. Distinguish inbreeding from out breeding
2. Define Amniocentesis.
3. What is Trisomy. 21
4. Comment on Wiener’s hypothesis.
5. Comment on chargaff rule.
6. Comment on Random genetic drift.
7. Differentiate virulent phage from non-virulent phage.
8. Comment on Germ-line mosaicism.
9. What is cistron?
10. What is Law of Independent assortment?
PART – B
Answer any FOUR:
(4 x 10 = 40)
11. State the Hardy Weinberg Law of Equilibrium.
12. Explain in what respect the discovery of Multiple alleles contribute to concept of the gene.
13. Give an account on chromosomal aberration and categorise numerical and structural aberration.
14. Describe the Operon concept in bacteria with its significance and genetic properties.
15. Give an account on sex linked inheritance with a suitable example.
16. Write a note on inherited metabolic disorders in man.
PART – C
Answer any TWO
(2 x 20 = 40)
17. DNA is genetic material in bacteria and most viruses. Discuss.
18. Give an illustrative account of bacterial conjugation, transformation and transduction with
suitable diagrams.
19. Why did Mendel choose pea as the experimental material in his hybridization experiment? Give
an account of the Procedure and methods of drawing the conclusion from the result of the
experiment.
20. Write an essay on genetic counselling in rare diseases and its complication.
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