LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 M.Sc. DEGREE EXAMINATION - MEDICAL SOCIOLOGY. THIRD SEMESTER – November 2009 SO 3803 - COMMUNITY HEALTH AND SOCIAL MEDICINE Date : 11/10/2009 Time : 9:00 - 12:00 Dept. No. Max. : 100 Marks SECTION-A Answer ALL questions [10 x2 =20 marks] 1. Distinguish between pluripotent and multipotent stemcells. 2. Define the following a). Ovasome. b). Neurotranmitters 3. Mention the sources of stemcells for Alzheimer disease and liver failure. 4. Briefly explain cellcycle regulators. 5. Differentiate pronuclei from germinal vesicle. 6. Define muscular and hematological disorders. 7. What are scaffolds? 8. Define primordial germcells migration 9. What are stemcell banks? 10. Comment on the role of federal agencies promoting stemcell research. SECTION-B Answer ANY FOUR questions. [4X10 =40 marks] 11. Discuss the developmental potential of transplanted nuclei in mammalian zygote and cleaving blastomeres. 12. Elaborate on the process and applications of tissue engineering in the treatment of cardiovascular diseases. 13. Give an account of therapeutic cloning, Bring out its merits and demerits? 14. Explain the process of embryonic and adult stemcell differentiation giving examples. 15. Describe the organogenesis of an embryo during fifth and sixth week of development. 16. Write a comparative account on fetal tissue stemcells and adult stemcells. SECTION-C Answer ANY TWO questions. [2X20 =40 marks] 17. Write an essay on the promises of stem cells in the treatment of neurodegenerative diseases. 18. Explain the various types of egg activation and comment on their applications in stem cell research. 19. Describe the technology of assisted reproduction emphasizing their merits in human infertility. 20. Describe the mechanism and factors involved in oocyte maturation. ********