LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
B.Sc. DEGREE EXAMINATION – ADVANCED ZOOLOGY & BIOTECH.
FIFTH SEMESTER – NOVEMBER 2012
AZ 5513 - GENETICS
Date : 06/11/2012
Time : 9:00 - 12:00
Dept. No.
Max. : 100 Marks
PART - A
ANSWER ALL QUESTIONS:
(10 x 2 = 20)
1. Differentiate between Auto and Allo polyploidy.
2. What is test cross? Give its significance.
3. What blood phenotypes would you expect among the offspring of the following cross?
IA i X IB i.
4. Give an example for each of the following:
a) Sex linked inheritance
b) Incomplete dominance.
5. Define the following:
a) Nondisjunction
b) Allosomes.
6. Highlight the significance of Amniocentesis.
7. Draw a neat labeled diagram of tRNA.
8. Comment on Lethal genes.
9. Distinguish Lytic from lysogenic cycles.
10. State Hardy-Weinberg principle.
PART - B
ANSWER ANY FOUR OF THE FOLLOWING:
(4 x 10 = 40)
11. When will the dihybrid cross ratio, 9:3:3:1 get modified to 9:7? Explain with a suitable example.
12. Describe the mode of inheritance of skin colour in man.
13. Explain the process of replication of DNA.
14. “Shell coiling in Limnaea is an example for Cytoplasmic inheritance”. Justify.
15. Discuss the advantages and disadvantages of Inbreeding and Outbreeding.
16. Give a brief account on Eugenics.
PART - C
ANSWER ANY TWO OF THE FOLLOWING:
(2 x 20 = 40)
17. Give an account of Inborn Errors of Metabolism.
18. With suitable diagrams describe the Operon model for the genetic control of lactose metabolism.
19. Explain the three different mechanisms for transfer of genetic material and recombination in Bacteria.
20. Discuss in detail the principle, procedure, applications and ethical implications of genetic engineering.
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