LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION - MEDICAL LAB. TECH.
SECOND SEMESTER – APRIL 2008
LM 07
ML 2809 - IMMUNOLOGY
Date : 22/04/2008
Time : 1:00 - 4:00
Dept. No.
Max. : 100 Marks
SECTION A
Answer ALL the questions:
(10 x 2 = 20 Marks)
1. What is MALT?
2. What are super antigens?
3. What are Freund’s complete and incomplete antigens?
4. Mention the biological activities of the subclasses of IgG.
5. How are grafts classified?
6. What are the three categories of disease treatable by bone marrow transplantations?
7. Differentiate attenuated and inactivated vaccines.
8. What are subunit vaccines?
9. Define anti idiotype antibody.
10. What are thymus dependent antigens?
SECTION B
Answer any FOUR of the following
(4 x 10 = 40 Marks)
11. Write briefly on primary lymphoid organs.
12. Give an account on the structure of MHC molecules.
13. Give a brief account on monoclonal antibody production. Add a note on its applications.
14. Give a descriptive account of immune response against protozoan parasites.
15. Write briefly on the immunosuppressive therapies during transplantation.
16. Write briefly on the different types of ELISA test.
SECTION C
Answer any TWO of the following
(2 x 20 = 40 Marks)
17. Define interleukins. Give an account of the source and functions of IL-1 to IL-20
18. What is hypersensitivity? Write in detail on IgE mediated hypersensitivity?
19. Give a detailed schedule of vaccination in childhood and adults.
20. Explain in detail the different methods involved in demonstration of agglutination reaction.
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