The Danish Invasion The Danish National Hypothermia Team Use of portable ECMO-device in hypothermic patients and alternative applications C. Simonsen1,, B. Kjærgaard1,2 Danish Armed Forces Health Services 1. Dept. of Cardiothoracic surgery, Center for Cardiovascular Research, Aalborg University Hospital. Royal Danish Armed Forces Health Service, RDAF SAR SQN 722 2. Biomedical Research Laboratory, Aalborg University Hospital. 1 Disclamers The authors of this presentation has no commercial or financial interest in the matters discussed. Opinions expressed in this presentation are personal opinions of the authors and do not necessarily reflect the policy of the Royal Danish Air Force. Danish Armed Forces Health Services 2 Overview • The team – organisation • Hypothermia – The Danish approach • Case with ECMO treated severe hypothermia • Case with ECMO used in a trauma setting Danish Armed Forces Health Services 3 Location 1 hour xxx Danish Armed Forces Health Services 4 The Team • 1 Thoracic Surgeon • 1 Perfusionist • Team is alerted by Request from other hospital or AMK (Acute Medical Coordination). • If needed AMK Request Helicoptor assistance via Joint Rescue Coordination Centre (JRCC) Danish Armed Forces Health Services 5 ECMO Danish Armed Forces Health Services 6 How did it start? 1999: Research started for the implementation of ECMO 300-400 kg 40 kg First patient treated in 2004 Danish Armed Forces Health Services 7 Hypothermia: The Danish approach Focuses on the clinical condition and not solely on the core temperature 1. Mild hypothermic patient: Below 35°C. Awake (Glasgow Coma Scale > 8). 2. Moderate hypothermic patient: Below 32°C and unconscious. 3. Severe Hypothermic patient: Below 32°C, unconscious and abscent respiration/ circulation. Danish Armed Forces Health Services 8 Treatment: Strategies 1. Mild hypothermic patient: Below 35°C. Awake (Glasgow Coma Scale > 8). Treatment: ABC, External warming 2. Moderate hypothermic patient: Below 32°C and Unconscious. Treatment: ABC, rewarmed by pleural lavage. 3. Severe Hypothermic patient: Below 32°C, unconscious and abscent respiration/circulation. Treatment: ABC including CPR. Rewarming can be established by extra corporeal circulation Unless patient is dead! Danish Armed Forces Health Services 9 Oxygen need 37 ºC = 100 % 20 ºC = 20 % Some die of hypothermia Some survive because of hypothermia Cooling to 20 ºC and 2 hours without circulation: Rewarming….. Danish Armed Forces Health Services 10 Treatment: When to stop As a guideline the following criteria are used when deciding to terminate resuscitation: • Asystole and P-potassium > 10 mmol/l • Asystole and temperature > 32 oC • Cadaverositas – (NOT rigor mortis/livor mortis) Danish Armed Forces Health Services 11 The Præstø Case Water temperature: 2oC Air temperature: 4 oC Wind: 7-13 m/s (14-25 knots) Danish Armed Forces Health Services 12 The Præstø Case February 2011: 13 teenagers and 2 teachers in a little boat 14 were rescued Danish Armed Forces Health Services 13 The Præstø Case 7 of the rescued teenagers suffered from cardiac arrest. • Dilated unresponsive pupils • The core temperature 15,5-20,2 °C • pH-level between 6.43–6.94 • ECMO established 178–241 min after the accident. Danish Armed Forces Health Services 14 The Præstø Case 6 was transferred to Copenhagen University Hospital Rigshospitalet and treated with ECMO Danish Armed Forces Health Services 15 The Præstø Case Andreas Danish Armed Forces Health Services 16 The Præstø Case 4 months later Danish Armed Forces Health Services 17 The Præstø Case Boring but important Table Patient Danish Armed Forces Health Services M/F Age EMS Temp. pH CC GCS ECG ECMO 1 M 15 121 16,0 6,59 57 3 VF 178 2 M 16 121 20,2 6,62 56 3 VF 179 3 M 15 168 18,4 6,43 65 3 AS 233 4 F 16 153 15,5 6,61 88 3 PEA 241 5 F 15 168 19,4 6,90 58 3 VF 226 6 M 16 108 17,5 6,52 120 3 VF 228 7 M 17 108 20,0 6,94 ? 3 AS 233 8 M 16 106 34,2 ND ND 15 SR ND 9 F 16 108 23,0 7,00 2 3 PVC ND 10 F 16 91 36,4 ND ND 15 SR ND 11 F 16 104 27,5 7,27 ND 12 SR ND 12 F 17 96 37,5 ND ND 15 SR ND 13 F 16 113 35,9 7,33 ND 15 SR ND 14 F 33 96 28,0 ND ND 12 SR ND EMS= time for first contact with emergency medical services, CC=duration of chectcompression 18 The Præstø Case Outcome Danish Armed Forces Health Services 19 Tractor incident 18. september 2014 67 years old farmer run over by tractor. Danish Armed Forces Health Services 20 Tractor incident • • • • • • • Multiple rib fractures Pneumothorax Hemothorax Lung contusion Crushed pelvis Intra abdominal injuries GCS 3 Danish Armed Forces Health Services 21 Tractor incident Needed emergency surgery • Insufficient oxygenation • Bleeding • Cold Danish Armed Forces Health Services 22 Tractor incident Veno-venous ECMO Danish Armed Forces Health Services 23 Tractor incident Danish Armed Forces Health Services 24 Tractor incident Discharged after 4 months • Ileostomy • Cerebral- and kidney function was intact • No major disabilities Danish Armed Forces Health Services 25 ECMO: Alternative applications Buy time for • Diagnostics (e.g. CT-scan, CAG) • Intervention (PCI, surgery) • Recovery Danish Armed Forces Health Services 26 Hypothermia Team Activities 2004-2015 270 cases Danish Armed Forces Health Services 27 Perspective Long distance evacuation (2006) Danish Armed Forces Health Services 28 Perspective Potential for further advanced methods • Novalung (pumpless ECMO) • Impella • Even smaller ECMO-machine (standard equipment?) Prototype: 4 kg Danish Armed Forces Health Services 29 Conclusion As with the hypothermic patient, huge benefits can be achieved when bringing portable ECMO-device and capable personnel to other types of critical illness/traumas e.g. • • • • • Danish Armed Forces Health Services Asthma attacks Heart attacks Pulmonary embolism Severe pneumonias Blast lungs Long distance evacuation while patient is on ECMO is possible. 30 Thank You! Denmark offers excellent conditions for further research in MEDEVAC using cardio-pulmonary assist • Experience with porcine models • Tradition for civil/military cooperation • Legislation regarding research animals International cooperation within this field of research is welcomed! Danish Armed Forces Health Services 31