Obsessions and addictions – what do they tell us about normal behaviour? FREDERICK TOATES S–R link Stimulus Response CNS (a) State S–R link Stimulus State Stimulus Response CNS (b) Cognition S–R link Response CNS (c) Changing Weight a) The properties of behaviour depend upon the particular relative weight attached to the factors. b) The relative weight of these factors that is necessary for optimal performance differs according to circumstances. c) Changing performance under changing conditions often reflects such a shift; and d) Under sub-optimal conditions the weight distorts, such as to lead to behavioural pathology. Factors that Change the Weight of Offline/On-line Controls a) Development b) Learning c) Phylogeny d) Brain damage e) Chemical influences Type of obsession Harm/ aggressive threat (fears about one’s own well-being and that of loved ones or of inflicting damage) Type of compulsion Intrusive thoughts related Seek physical proximity; to harm/ loss check on well-being of loved one; take preemptive action, e.g. to avoid possible triggers, accidents; seek evidence that one has not performed some awful deed in the past Moral threat Intrusive thoughts /images about a morally unacceptable sexual behaviour Avoid possible triggers/ seek reassurance Cleanliness threat (fears about contamination) Intrusive thoughts that hands are not clean or that germs might contaminate oneself or others Washing and cleansing behaviour Religious threat Blasphemous thoughts Reassurance/ protracted religious rituals A sequence of OCD logic • The photographer must have been close to Hudson because the photo was a “close up” • So the photographer himself might have been contaminated. • So, when he developed the negative, he could have contaminated it. • The negative was in contact with the print of the photograph and so could have contaminated it. • The man in charge of printing the newspaper used the photograph, and so, he could have passed its contamination on to the newspaper’s printer. • The printing press could have passed the contamination on to the picture in every newspaper. • So, when I touched the newspaper, I too might have been contaminated. Addictive substances/activities • Food • Sex • • • • • Drugs Alcohol Heroin Cocaine Nicotine • Gambling • Shopping • Internet • Oil Comparison of OCD and addiction OCD addiction Motivational direction of underlying process avoid approach Perception of quality of intrusion negative Positive/negative External stimuli Can set off/ salience increase Can set off/ salience increase Head-on confrontation To be avoided To be avoided Behaviour therapy of exposure effective inappropriate Chemical interventions SSRIs effective in some cases SSRIs effective in some cases Role of stress Makes worse (increased distress by intrusions) Increased danger of relapse Makes worse (increased distress by intrusions) Increased danger of relapse Psychological treatment Guided diversion/challenge interpretation Guided diversion Abnormal Brain mechanisms Frontal cortex-striatum Frontal cortex-striatum T E N D E N C Y AVOID APPROACH DISTANCE APPROACH T E N D E N C Y AVOID DISTANCE