General & Comparative Animal Physiology (PCB 4723) Spring 2001 Subject Area: Comparative Physiology is the study of the physiological and biochemical mechanisms of adaptation of animals to their micro-habitats. When faced with common problems (heat stress, osmotic shock etc.), different animal groups often acquire highly divergent physiological solutions. Furthermore, it is quite common for unrelated groups to evolve similar adaptive solutions to common problems by convergence. In this course we will explore physiological & biochemical processes in a range of animals focusing on invertebrate and lower vertebrate systems. Emphasis will be placed on aquatic species. Objectives: 1. Familiarize students with basic physiological processes in a range of animals living in different habitats. 2. Develop critical thinking skills. 3. Improve written communication skills. 4. Familiarize students with graphical representation of experimental data. 5. Develop familiarity with the primary scientific literature. Meeting Time and Place: T,R 8-9:15, 208 Bio Unit I. Instructor: W. Ross Ellington, Professor & Director, Institute of Molecular Biophysics and the Structural Biology Program. I was trained as a card-carrying comparative physiologist and still serve on the editorial boards of American Journal of Physiology, Comparative Physiology & Biochemistry and Journal of Comparative Physiology B. However, roughly 10 years ago I reinvented myself scientifically shifting my research efforts to more biophysical/biochemical issues, primarily the study of the structure, function and evolution of enzymes. Office hours: Thursdays 9:30 –11:00 (Bio 239) or by appointment (644-5406; elling@bio.fsu.edu); I always respond within 24 hours to email questions. WEB Resources: Various resources for PCB 4723 will be posted on my website. Go to the following web address: http://www.bio.fsu.edu/faculty-ellington_undergradteaching.htm and choose PCB 4723. STUDENTS WITH DISABILITIES: If you have any kind of disability that impacts your learning and/or test-taking, please bring this to my attention as soon as possible. I will be happy to accommodate your needs. 1 Grading: Three equally weighted (100 points each) discussion-type exams (2 during the semester) and a research paper (100 pts); total of 400 pts. A 370 pts or higher A- 360 pts B+ 350 pts B 330 pts B- 320 pts C+ 310 pts C 290 pts C- 280 pts D+ 270 pts D 250 pts D- 240 pts F below 240 pts (Note: minor adjustments may be made to the scale based on class performance; it will never be made more stringent) Research Paper: You will be required to write a research paper. Details about the paper and format can be found on the course website. Course Policy: 1. If you are going to miss an exam, you MUST CONTACT ME IN ADVANCE by phone (I have voicemail) or email. At this time I will schedule a make-up exam which must be taken no later than 48 hours after the regularly scheduled exam. 2. If you believe that I made a mistake grading your exam, please – (a) look over the posted key, (b) write down your concerns on a separate sheet of paper, (c) attach this to your exam and give it to me and (d) I will promptly review your concerns. 3. The Academic Honor System of the Florida State University is based on the premise that each student has the responsibility a) to uphold the highest standards of academic integrity in the student’s own work, b) to refuse to tolerate violations of academic integrity in the University community, and c) to foster a high sense of integrity and social responsibility on the part of the University community. You are expected to adhere to all aspects of the Academic Honor Code in this course. 4. Grades will note be posted nor am I permitted to communicate these by email or telephone. 2 Textbook: Knut Schmidt-Nielson, Animal Physiology (5th Ed); Readings are listed in the course schedule. The textbook is there to provide background and clarification. Succeeding in this Course: 1. Do text readings in advance. 2. Come to class. 3. The night after each lecture, make a second set of abbreviated notes which highlight the major points that I covered. 4. You can use the full notes, abbreviated notes and text for study. 5. Study in groups. Ask each other to explain particular mechanisms and processes. 6. Practice interpreting graphs. Course Schedule: Topic Text 1/9 1/11 1 2 Introduction; Gas exchange Physical aspects of gas exchange 1/16 1/18 1/30 2/1 2/6 2/8 2/13 3 4 5 6 7 8 2/15 2/20 2/22 2/27 3/1 3/6 3/8 3/13 9 10 11 12 13 14 Gas exchange- water Gas exchange-bimodal & air Gas transport Gas transport Hypoxia Hypoxia Exam # 1; 100 pts, lectures 1-8 ***RESEARCH PAPER TOPIC FORM DUE*** Diving Physiology Buoyancy Acid-base balance Physical aspects of temperature change Poikilothermy Poikilothermy Spring Break Spring Break 3 5-17; 585-587 17-25 36-61 61-82 173-178 178-192 442--458 82-87 217-225 232-238 3/15 3/20 3/22 3/27 15 16 17 Homeothermy Heterothermy Exam # 2: 100 pts, lectures 9-16 Introduction to water & ion balance 3/29 18 Freshwater 4/3 4/5 4/10 19 20 No Class- WRE at Experimental Biology meetings Estuarine Marine ***RESEARCH PAPER DUE IN CLASS*** 4/11 4/17 4/19 4/26 21 22 23 Terrestrial Hypersaline & anhydrobiosis Nitrogen excretion and environment Final Exam (Exam4; lectures 17-22), Thursday, 3-5 PM 4 241-277 284-293 301-305; 591-594 310-314, 320-323 309-310 305-309, 314-320, 343-351 366-377 378-388