The trouble with the integers is that we have examined only the
small ones. Maybe all the exciting stuff happens at really big
numbers, ones we can't get our hands on or even begin to think
about in any very definite way. So maybe all the action is
really inaccessible and we're just fiddling around. Our brains
have evolved to get us out of the rain, find where the berries
are, and keep us from getting killed. Our brains did not evolve
to help us grasp really large numbers or to look a things in a
hundred thousand dimensions.
--Ron Graham,
from preface of Wonders of Numbers: Adventures in Mathematics,
Mind and Meaning" by Clifford Pickover, Oxford Univ Pr 2000,
ISBN: 0195133420