Chapter 45 Nursing Assessment Urinary System S. Buckley, RN, MS ( adapted from Mosby pp) Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Renal A & P websites 1. A & P http://www.youtube.com/watch?v=cc8sUv2SuaY&feature=related another animated a&p http://www.youtube.com/watch?v=aQZaNXNroVY&feature=related 1. urine formation http://health.howstuffworks.com/human-body/systems/kidneyurinary/adam-200032.htm 2. kidney anatomy http://www.youtube.com/watch?v=SVl81H7H5J4&feature=related http://www.youtube.com/watch?v=vEXx5YLcGmQ&feature=related Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Structures and Functions of the Urinary System Kidneys Macrostructure Microstructure Blood supply Primary function of kidneys: 1. regulate volume and composition of extracellular fluid (ECF) 2. excrete waste products from body. Physiology of urine formation • Glomerular function • Tubular function Other functions of the kidney; control blood pressure, produce erythropoietin, activate vitamin D, regulate acid-base balance. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Fig. 45-1 Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Fig. 45-2 Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Nephron Basic function is to clean or clear blood plasma of unnecessary substances Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Fig. 45-3 Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Physiology of urine formation * Primary function of kidneys: filter blood, maintain body’s internal homeostasis. * Multistep process of: filtration, reabsorption, secretions, excretion of water, electrolytes and metabolic waste. * Urine formation begins at glomerulus (blood filtered) * Glomerular filtration rate (GFR)-amount of blood filtered by the glomeruli in a given time, normal is ~ 125ml/min. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Water balance, acid-base balance Function of: 1. ADH 2. Aldosterone 3. HCO3 and H+ (acid/base balance) 4. ANP Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Antidiuretic hormone (ADH)-required for water reabsorption in the kidney , important in fluid balance. makes tubules and collecting ducts permeable to water, allowing water to be reabsorbed into the peritubular capillaries and returned to the circulation. Functions in concert with hypothalamus and neural input as loop mechanism decreases urine output Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. aldosterone Released from adrenal cortex, acts on distal tubule to cause reabsorption of Na+ and water. Influenced by blood concentrations of Na+ and K+ In exchange for Na+ reabsorption, potassium ions (K+) are excreted. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Acid base regulation Reabsorbing and conserving bicarbonate (HCO3) and secreting Hydrogen (H+) in response ph of ECF Distal tubule functions to maintain the ph of ECF within range of 7.35-7.45. Metabolic response to ph along with respiratory acid/base balance. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Atrial Natriuretic peptide (ANP) Hormone secreted from cells in R atrium in response to atrial distention due to an increase in plasma volume. Acts on kidneys to increase Na+ excretion. Inhibits renin, ADH and action of angiotensinII on the adrenal glands, thus suppresses aldosterone secretion. ANP causes relaxation of afferent arteriole, thus increasing the GFR Combined effects of ANP=production of large volume of dilute urine Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Fig. 45-4 Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Other Kidney functions (continued) Erythropoietin-stimulates the production of red blood cells (RBCs) in bone marrow produced and released in response to hypoxia and decreased renal blood flow. In renal failure, a deficiency of erythropoietin occurs leading to anemia Vitamin D-hormone obtained in diet and sun. requires metabolism in liver and kidney to be “activated”, essential for absorption of Ca+ from GI tract. In renal failure manifestation of problems of altered Ca+ and PO2 balance. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Other Kidney functions Calcium balance -parathyroid hormone (PTH) is released from parathyroid gland in response to low serum ca+ levels. PTH works by causing increased tubular reabsorption of CA2+ and decreased tubular reabsorption of phosphate ions (PO4 2-) In renal disease, the effects of PTH may have major effect on bone metabolism. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Other Kidney functions (continued) Renin-regulates BP, involved in splitting of angiotensin cascade (p. 1138). Angiotensin II stimulates release of aldosterone (causes Na+ and water retention leading to increased ECF volume) Also causes peripheral vasoconstriction. (both increase BP) Produced and secreted by cells in kidneys, released into blood in response to decreased; renal perfusion, arterial BP, ECF, Na+ Released into blood in response to increased urinary Na+ concentration Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Other kidney functions (continued) Prostaglandins (PGs)- involved in the regulation of cell function and host defenses PG synthesis occurs in the medullla of the kidney. PGs increase renal blood flow and promote Na+ excretion. Counteract the vasoconstrictor effect of angiotensin and norepinephrine =decreased systemic vascular resistance= decreased BP. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Structures and Functions of the Urinary System (cont’d) Ureters-~12 inches, carry urine from renal pelvis to bladder, can become obstructed with calculi (resulting in renal colic). Bladder Urethra-conduit for urine from bladder neck to outside body, external sphincter; rhabdosphincter Female-1-2 in. , male-8-10in. Urethrovesical unit-consists of bladder, urethra, pelvic floor muscles, normal voluntary control is defied as continence. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Urinary Bladder Serves as reservoir for urine Bladder muscle-detrusor muscle Normal urine output, ~1500ml/day, varies with intake of food and water, diurnal pattern. ~250ml of urine in bladder cause moderate distention and urge to urinate. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Fig. 45-5 Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Female/Male anatomy Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Gerontologic Considerations Effects of Aging on the Urinary System 20-30% decrease in size with aging, by 70 yrs old, 30-50% of glomeruli have lost function. Decreased renal blood flow, decreased GFR, alterations in hormone levels (ADH, aldosterone, ANP=decreased urinary concentration, limitations in excretion of water, Na+, K+ and acid). Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Benign prostatic hyperplasia (BPH) 1. Enlargement of prostate Prevalence-50% of men over 50 yrs, 90% of men over 80 yrs. Symptoms result from urinary obstruction; Obstructive symptoms-decrease in caliber and force of urinary stream, difficulty initiating voiding, intermittency, dribbling 2. Irritative symptoms- (associated with inflammation or infection)- frequency, urgency, dysuria, nocturia, incontinence Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. BPH (continued) Complications-urinary retention, UTI; potential sepsis, urinary calculi, hydronephrosis leading to renal failure, pyelonephritis, bladder damage. Diagnostic-DRE (digital rectal exam), PSA ( prostatespecific antigen-blood level associated with ca and BPH) Collaborative care-drug therapy, diet, catheterization, surgery (TURP), laser prostatectomy, stent placement, monitor for infection, hemorrhage, education, emotional support. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Incontinence in elderly DESIGN OF STUDY: Cross-sectional survey to measure prevalence of urinary incontinence, the impact on people's lives, use of protection, and health services. SETTING: Stratified random sample of 2000 community-living elderly (equal numbers of men and women, aged 65 to 74 years and over 75 years) in 11 general practices in a British city. RESULTS: The response rate was 79%. The overall prevalence of incontinence in the previous month was 31% for women and 23% for men. Women generally had more severe frequency of incontinence and a greater degree of wetness than men. Protection use was greater in women than in men. Br J Gen Pract. 2001 July; 51(468): 548–552. PMCID: PMC1314046Copyright notice Urinary incontinence in older people in the community: a neglected problem? H Stoddart, J Donovan, E Whitley, D Sharp, and I Harvey Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Women’s gerontological urinary issues Urethrovesical unit undergoes loss of elasticity, vascularity and structure, may result in incontinence (stress), irritation, bladder infections, prolapse Hormonal changes result in decrease in estrogen, mucosal dryness and irritation (cystitis) Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Women’s gerontological issues Research: Incidence of urinary incontinence in postmenopausal women treated with raloxifene or estrogen Goldstein, Steven R. MD; Johnson, Susan MD; Abstract Objective: Determine the effect of raloxifene or estrogen, as compared with placebo, on the reporting of urinary incontinence in postmenopausal women participating in an osteoporosis prevention trial. Conclusion: During 3 years of follow-up, conjugated equine estrogen was associated with an increased incidence of reports of urinary incontinence in women with a prior hysterectomy and this was significantly greater than both placebo and raloxifene. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Incidence of uti Most common bacterial infection, not reportable (US) 7 million office visits, 1million ER visits, 100,000 hospitalizations. 1in 3 women will have 1 episode requiring antibiotics by age 24, ½ of all women in lifetime Increased in pts with; infants, pregnancy, aids, ms, dm, BPH Catheter associated uti: most common nosocomial, >1million cases a year. Costs: 1.6 billion. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Conditions impacting voiding Any disease or trauma that affects function of the brain, spinal cord, nerves that innervate bladder, sphincter or pelvic floor can affect bladder function. These include: DM, MS, paraplegia, quadriplegia, spinal problems, drugs affecting nerve transmission. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Assessment of the Urinary System Subjective data Important health information • Past health history-related diseases, surgeries, include family hx, occupation/environment, diet, water intake, exercise, elimination pattern • Smoking hx; major factor in risk for bladder ca. tumors occur 4x more frequently . • Medications • Surgery or other treatments Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Assessment terms (p.1145) Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Assessment of the Urinary System (cont’d) Functional health patterns • Health Perception–Health Management Pattern • Nutritional-Metabolic Pattern • Elimination Pattern • Activity-Exercise Pattern • Sleep-Rest Pattern • Cognitive-Perceptual Pattern • Self-Perception–Self-Concept Pattern • Role-Relationship Pattern • Sexuality-Reproductive Pattern Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Assessment of the Urinary System (cont’d) Objective data Physical examination • Inspection • Palpation • Percussion • Auscultation Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Fig. 45-6 Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Diagnostic Studies of the Urinary System Urine studies- accuracy of results influenced by: proper procedure, pt. cooperation, often require bowel prep (KUB, IVP). Urinalysis; 1st test done, best obtained in am, Creatinine clearance- Creatinine: waste product produced by muscle breakdown, most accurate indicator of renal function Normal value: 85-135 ml/min Serum creatinine: 0.5-1.5mg/dl BUN-10-30gm/dl Urodynamics; measures urinary tract function Specific gravity; 1.003-1.030 Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Fig. 45-7 Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Fig. 45-8 Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Fig. 45-9 Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.