1. Describe the division of the Nervous system? 2. Differentiate between the functions of the sympathetic parasympathetic divisions of the autonomic nervous system 3. Identify the source gland for adrenalin and explain its role in the “fight or flight” response. 4. Differentiate between sympathetic and parasympathetic neurons? 5. List the important function of sympathetic and parasympathetic nervous system? 6. Identify and give the functions for each of the following Medulla oblongata Cerebrum Thalamus Cerebellum Hypothalamus Corpus callosum 7. Explain how the hypothalamus and pituitary gland interact as the neuroendocrine control centre (p. 371-373). and 1. Your brain uses 20% of your body's energy, but it makes up only 2% of your body's weight. 2. Your cerebral cortex is about as thick as a tongue depressor. It grows thicker as you learn and use it. 3. Your brain is about the size of a cantaloupe and wrinkled like a walnut. 4. Your brain generates 25 watts of power while you're awake--enough to illuminate a light bulb. 5. A newborn baby’s brain grows almost 3 times in course of first year . 6. Toxins in commonplace items such as carpeting and shower curtains may be contributing to memory loss over time? And overexposure to aluminum compounds—in foil, cookware, deodorants, antacids, and toothpaste—can affect brain function 7. Lavender can help you sleep. A cooked potato can jump-start your brain when you're feeling foggy. The essential oil of jasmine can restore mental alertness 8. Eating foods rich in vitamins E and C, & beta-carotene may help lower your risk of Alzheimer’s disease. 9. The human brain is ~75% water. 10. Neurons multiply at a rate 250,000 neurons per minute during early pregnancy. The nervous system is not a ‘normal’ system. It is made up of neurons (3 types) not organs. It controls almost every organ system through negative and positive feedback loops. involuntary voluntary The Central Nervous System (CNS) integrates the information it receives from all over the body in order to make decisions. CNS composed of the brain and spinal cord. The CNS is entirely enclosed 3 layers of membranes (meninges) and in bone: the skull and vertebrae. Cerebral Spinal Fluid and tissue also insulate the brain and spinal cord. After puberty, we lose ~10,000 neurons in the CNS every day, and no new neurons are made. During embryonic development, the brain forms as a tube (neural cord). 1. Anterior becomes the brain. 2. Posterior becomes the spinal cord. The brain has 3 main parts: 1. The Cerebrum 2. The Cerebellum 3. The Medulla oblongata The cerebrum is the largest portion of the brain. It is divided into a right and left cerebral hemispheres, which are separated by the corpus callosum. The hemispheres are covered by a thin layer known as the cerebral cortex, which is the most recently evolved part of the brain. It is responsible for intelligence The cerebrum coordinates sensory data and motor functions. It is where memory is kept; where conscious thought processes are made; where a lot of interneural connections are made. When impulses require some processing before responses are made, this is where they go (ie: responding to a verbal question). Overall, the cerebrum governs intelligence and reasoning, planning, learning, memory, and personality. The cerebrum is divided into 4 lobes. 1. Frontal Lobe 2. Parietal Lobe 3. Occipital Lobe 4. Temporal Lobe No region of the brain functions alone, although the major functions of the lobes are: 1. The occipital lobe (back of the head) receives and processes visual information. 2. The temporal lobe receives auditory signals, olfactory signals, processing language and the meaning of words. 3. The parietal lobe is associated with the sensory cortex and processes information about touch, taste, pressure, pain, and heat/cold. 4. The frontal lobe conducts 3 functions: a) Motor activity & integration of muscle activity b) Speech c) Thought processes The corpus callosum is the dense tissue that holds the two hemispheres of the cerebrum together. It also conducts impulses from one side of the brain to the other. It is through this part of the brain that coordinates the activities of the two sides of the brain. The cerebellum is the 2nd largest part of the brain. This is the place where the impulses that give rise to movements are coordinated. The cerebellum coordinates small, smooth movements (as in fine motor control). The cerebellum also maintains normal muscle tone & posture, and coordinates balance (proprioception). The brain stem is the smallest and the oldest and most primitive part of the brain. The brain stem is continuous with the spinal cord, and is composed of: 1. Medulla oblongata 2. Pons The medulla oblongata is closest to the spinal cord, and is involved with the regulation of heartbeat, breathing, vasoconstriction (blood pressure). It also has reflex centers for vomiting, coughing, sneezing, swallowing, and hiccuping. The medulla oblongata contains receptors that are receptive to the conditions of the blood (such as too much CO2 which causes inhalation). Has control over the internal organs; it is the ‘unconscious’ part of the brain. The midbrain connects the hindbrain and forebrain. It controls our eye reflexes. The Thalamus directs the impulses that travel up the spinal cord to the correct region of the cerebrum. It is often referred to as the ‘sorting centre’ or ‘gatekeeper of the cerebrum’. It filters out extraneous and unimportant sensory stimuli to the higher brain. The Hypothalamus regulates homeostasis. It has regulatory areas for thirst, hunger, body temperature, water balance, and blood pressure. It also links the Nervous System to the Endocrine System. This part of the brain also has control over the internal organs. The hypothalamus samples the blood that travels through it and responds, either through the initiation of nerve impulses or by causing the pituitary gland to release hormones. The Pituitary Gland is also known as the ‘Master Gland’. This is a small gland with two parts: the anterior and posterior lobes. It produces a large number of hormones, many of which control the release of hormones from other glands in the body. Posterior Pituitary: This part of the gland releases the hormones that are made in the Hypothalamus, but are stored in the Posterior Pituitary. The hormones are transferred and stored in special hollow nerve fibres that run from the hypothalamus to the posterior pituitary. Examples of hormones: (eg. ADH and Oxytocin) Anterior Pituitary: This part of the gland makes and releases its own hormones. It is stimulated to release its hormones by the hypothalamus. There is a blood connection between the hypothalamus and the anterior pituitary. Examples of hormones: Growth hormone, Prolactin, FSH & LH, Thyroid Stimulating Hormone (TSH), Adrenal Cortex Stimulating Hormone (ACTH), Melatonin The spinal cord (dorsal nerve cord) runs along the dorsal side of the body and links the brain to the rest of the body. Vertebrates have their spinal cords encased in a series of (usually) bony vertebrae. Some tracts nerves are ascending (carrying messages to the brain), others are descending (carrying messages from the brain). The spinal cord is also involved in reflexes that do not immediately involve the brain. The spinal cord has 4 parts: Cervical: the neck region. *No peripheral nerves originate from this region. Thoracic: the thoracic cavity (lungs etc…) Lumbar: the abdominal cavity (guts, kidneys, liver…) Saccral: the tail bone area The Peripheral Nervous System (PNS) contains only nerves. It connects the brain and spinal cord (central nervous system) to the rest of the body. There are 12 pairs of Cranial nerves in the PNS that take impulses to and from the brain (CNS). These Cranial nerves can be either sensory (optic/olfactory) or motor (facial nerves) or a mixture of the two (tongue, facial skin). There are also 31 pairs of Spinal nerves which take impulses to and away from the spinal cord. There are 2 main components of the Peripheral Nervous System: 1. Somatic Nervous System 2. Autonomic Nervous System This system includes all of the nerves controlling: a) Voluntary musculo-skeletal region b) Exterior sense organs (with cranial nerves) c) Reflex arcs These are primarily under VOLUNTARY control. Most sensory input carried in the PNS remains below the level of conscious awareness. Input that does reach the conscious level contributes to perception of our external environment. Senses: Input to the nervous system is in the form of our five special senses: touch, vision, taste, smell, and hearing. There are also the somatic senses: Pain, temperature, and pressure. Sensory input begins with sensors that react to stimuli in the form of energy that is transmitted into an action potential and sent to the CNS. This system is made up of smooth muscle, cardiac muscle, and glands. The autonomic nervous system is that part of PNS consisting of motor neurons that control internal organs (ie: heart, intestine, bladder, uterus…) These are all under involuntary control; they happen automatically and without awareness. The autonomic nervous system is divided into 2 parts: 1. Sympathetic Nervous System 2. Parasympathetic Nervous System Sympathetic involves expenditure of energy (“fight or flight”) Parasympathetic restores or conserves energy (“return to normal”) Involved in the ‘fight or flight’ response. This system is stimulatory and prepares the body for action. These nerves come off the ganglia from the mid-region of the spinal cord. Sudden, simultaneous release of noradrenalin from all the sympathetic neurons (as in times of fright) has a critical effect. It causes the release of the hormone adrenalin from the medulla of the adrenal glands (located on top of the kidneys). The noradrenalin and adrenalin prepare the body for fight or flight in the following ways: 1. Increases heart rate & BP; more blood supplied to the body quickly 2. Widens air passageways so more air can be exchanged each breath 3. Sudden contraction of muscles to tense the body up for action. Included in this is the contraction of the diaphragm causing a ‘gasp’. 4. Iris of the eye contracts & widens pupil = maximum visual alertness. 5. Increased blood flow to skeletal muscles so they are more able to act. 6. Decreased digestive activity, circulation and control. The parasympathetic nervous system is involved in relaxation. The nerves come off the ganglia in the upper & lower parts of the spinal cord. It releases acetylcholine to return the body to its normal state after stress. It maintains a relaxed state. It has the exact opposite effect than the sympathetic NS. 1. 2. 3. 4. 5. 6. Decreases heart rate & BP to normal (120/80). Constricts air passageways back to normal. Relaxation of muscles. Iris of the eye relaxes and pupil returns to its normal size. Decreased blood flow to skeletal muscles. Increased digestive activity, circulation and control. Basis of Comparison Sympathetic Neurons Parasympathetic Neurons Effect Active body function Spinal origin Thoracic and lumbar Vegetative body function Cranial and sacral Neurotransmitter Noradrenalin Acetylcholine Restoring enzyme Monoamine oxidase Acetylcholinesterase Location of motor ganglion Closer to the CNS Farther from the CNS