Optimization of Protection in Computed Tomography (CT) Introduction • The subject matter: CT scanner and related image quality considerations • The importance of the technological improvement made in this field • The quality criteria system developed to optimize the CT procedure • Background: medical doctor, medical physicist 2 Topics CT equipment and technology Radiation protection rules and operational consideration Quality criteria for CT images 3 Overview • To understand the principles and the technology of CT • To be able to apply the principle of radiation protection to CT scanner including design, Quality Control and dosimetry. 4 Optimization of protection in CT scanner Topic 1: CT equipment and technology Introduction • Computed Tomography (CT) was introduced into clinical practice in 1972 and revolutionized X Ray imaging by providing high quality images which reproduced transverse cross sections of the body. • Tissues are not superimposed on the image as they are in conventional projections • The CT provides improved low contrast resolution for better visualization of soft tissue, but with relatively high radiation dose, i.e. CT is a high dose procedure 6 Computed Tomography • CT uses a rotating X Ray tube, with the beam in the form of a thin slice (about 1 - 10 mm) • The “image” is a simple array of X Ray intensities, and many hundreds of these are used to make the CT image, which is a “slice” through the patient 7 The CT Scanner 8 A look inside a rotate/rotate CT Detector Array and Collimator X Ray Tube 9 Helical (spiral) CT • If the X Ray tube can rotate constantly, the patient can then be moved continuously through the beam, making the examination much faster 10 Helical Scan Principle • Scanning Geometry X Ray beam Direction of patient movement • Continuous Data Acquisition and Table Feed 11 Helical CT Scanners • For helical scanners, the X Ray tube rotates continuously • This is obviously not possible with a cable combining all electrical sources and signals • A “slip ring” is used to supply power and to collect the signals 12 A Look Inside a Slip Ring CT X Ray Tube Detector Array Note: how most of the electronics are placed on the rotating gantry Slip Ring 13 New CT Features • The new helical scanning CT units allow a range of new features, such as: – CT fluoroscopy, where the patient is stationary, but the tube continues to rotate – multislice CT, where up to 128 slices can be collected simultaneously – 3-dimensional CT and CT endoscopy 14 CT Fluoroscopy • Real Time Guidance (up to 8 fps) • Great Image Quality • High Dose Rate • Faster Procedures (up to 66% faster than non-fluoroscopic procedures) • Approx. 80 kVp, 30 mA 15 Multi slice CT collimation 5mm 2,5mm 1mm 0,5mm 16 3D Stereo Imaging 17 CT Endoscopy 18 CT Scanner – Generator • High frequency, 30 - 70 kW – X Ray tube • Rotating anode, high thermal capacity: 3-7 MHU • Dual focal spot sizes: about 0.8 and 1.4 – Gantry • • • • • Aperture: > 70 cm of diameter Detectors: gas or solid state; > 600 detectors Scanning time: <1 s, 1 - 4 s Slice thickness: 1 - 10 mm Spiral scanning: up to 1400 mm 19 Image processing Reconstruction time: Reconstruction matrix: 256x256 – 1024x1024 Reconstruction algorithms: 0.5 - 5 s/slice Bone, Standard, High resolution, etc Special image processing software: 3D reconstruction Angio CT with MIP Virtual endoscopy CT fluoroscopy 20 Spiral (helical) CT Spiral CT and Spiral multislice CT: Volume acquisition may be preferred to serial CT • Advantages: dose reduction: • reduction of single scan repetition (shorter examination times) • replacement of overlapped thin slices (high quality 3D display) by the reconstruction of one helical scan volume data • use of pitch > 1 no data missing as in the case of inter-slice interval shorter examination time • to acquire data during a single breath-holding period avoiding respiratory disturbances • disturbances due to involuntary movements such as peristalsis and cardiovascular action are reduced 21 Spiral (helical) CT Drawbacks – Increasing of dose: • equipment performance may tempt the operator to extend the examination area – Use of a pitch > 1.5 and an image reconstruction at intervals equal to the slice width results in lower diagnostic image quality due to reduced low contrast resolution – Loss of spatial resolution in the z-axes unless special interpolation is performed – Technique inherent artifact 22 Optimization of protection in CT scanner Topic 2: Radiation protection rules and operational consideration Contribution to collective dose (I) • As a result of such technological improvements, the number of examinations have markedly increased • Today CT procedures contribute for up to 40% of the collective dose from diagnostic radiology in all developed countries • Special protection measures are therefore required 24 Examination Mean effective dose (mSv) Routine head 1.8 Posterior fossa 0.7 Orbits 0.6 Cervical spine 2.6 Chest 7.8 Abdomen 7.6 Liver 7.2 Pelvis 7.1 Lumbar spine 3.3 CT scanners in clinical use in UK Contribution to collective dose (II) 500 400 300 200 100 0 70 75 80 85 90 95 Years 25 Justification of CT practice • Justification in CT is of particular importance for RP • CT examination is a “high dose” procedure • A series of clinical factors play a special part – Adequate clinical information, including the records of previous imaging investigations, must be available – In certain applications prior investigation of the patient by alternative imaging techniques might be required • Additional training in radiation protection is required for radiologists and radiographers • Guidelines of EU are available 26 Optimization of CT practice • Once a CT examination has been clinically justified, the subsequent imaging process must be optimized • There is dosimetric evidence that procedures are not optimized from the patient radiation protection point of view CTDIw (mGy) Examination Sample size Mean SD Min 25% Median 75% Max Head 102 50.0 14.6 21.0 41.9 49.6 57.8 130 Chest 88 20.3 7.6 4.0 15.2 18.6 26.8 46.4 Abdomen 91 25.6 8.4 6.8 18.8 24.8 32.8 46.4 Pelvis 82 26.4 9.6 6.8 18.5 26.0 33.1 55.2 27 Optimization of CT practice • Optimal use of ionizing radiation involves the interplay of the imaging process: Diagnostic quality of the CT image Radiation dose to the patient Choice of radiological technique 28 Optimization of CT practice • CT examinations should be performed under the responsibility of a radiologist according to the national regulations • Standard examination protocols should be available. • Effective supervision may aid radiation protection by terminating the examination when the clinical requirement has been satisfied • Quality Criteria can be adopted by radiologists, radiographers, and medical physicists as a check on the routine performance of the entire imaging process 29 Optimization of protection in CT scanner Topic 3: Quality criteria for CT images Quality criteria for CT images: Example of good imaging technique (brain general examination) Patient position Volume of investigation Supine Nominal slice thickness 2 - 5 mm in posterior fossa; 5-10 mm in hemispheres Inter-slice distance/pitch Contiguous or a pitch = 1 FOV Head dimension (about 24 cm) 10-12 ° above the orbito-meatal (OM) line to reduce exposure of the eye lenses Standard Gantry tilt X Ray tube voltage (kV) Tube current and exposure time product (mAs) Reconstruction algorithm Window width Window level From foramen magnum to the skull vertex As low as consistent with required image quality Soft 0 - 90 HU (supratentorial brain) 140- 160 HU (brain in posterior fossa) 2000 - 3000 HU (bones) 40 - 45 HU (supratentorial brain) 30 - 40 HU (brain in posterior fossa) 200 - 400 HU (bones) 31 Quality criteria for CT images: brain, general examination Image criteria Visualization of • Whole cerebrum, cerebellum, skull base and osseous basis • Vessels after intravenous contrast media Critical reproduction • Visually sharp reproduction of the border between white and grey matter basal ganglia ventricular system cerebrospinal fluid space around the mesencephalon cerebrospinal fluid space over the brain great vessels and the choroid plexuses after i.v. contrast Criteria for radiation dose to the patient • CTDIW 60 mGy • DLP 1050 mGy cm 32 Image criteria for CT images: brain, general examination (visualization of) • Whole cerebrum, cerebellum, skull base and osseous basis • Vessels after intravenous contrast media 33 Image criteria for CT images: brain, general examination (critical reproduction) Visually sharp reproduction of the: • border between white and grey matter • basal ganglia • ventricular system • cerebrospinal fluid space around the mesencephalon • cerebrospinal fluid space over the brain • great vessels and the choroid plexuses after i.v. contrast 34 Quality criteria for CT images • A preliminary list of reference dose for the patient are given for some examinations expressed in term of: – CTDIw for the single slice – DLP for the whole examination Examination Reference doses CTDIw (mGy) DLP (mGy cm) Routine head 60 1050 Routine chest 30 650 Routine abdomen 35 800 Routine pelvis 35 600 35 Viewing conditions and film processing Viewing conditions • It is recommended to read CT images on video display • Brightness and contrast control on the viewing monitor should give a uniform progression of the grey scale • Choice of window width dictates the visible contrast between tissues Film Processing • Optimal processing of the film has important implications for the diagnostic quality • Film processors should be maintained at their optimum operating conditions by frequent (i.e., daily) quality control 36 Summary • The CT scanner technology and the related radiation protection aspects • The ways of implementing the quality criteria system related to the image quality and to dosimetry • The importance of Quality Control 37 Where to Get More Information (II) • Quality criteria for computed tomography, EUR 16262 report, (Luxembourg, EC), 1997. http://w3.tue.nl/fileadmin/sbd/Documenten/Leerga ng/BSM/European_Guidelines_Quality_Criteria_Com puted_Tomography_Eur_16252.pdf • Radiation exposure in Computed Tomography; 4th revised Edition, December 2002, H.D.Nagel, CTB Publications, D-21073 Hamburg 38 CT Dose Reduction Techniques A Practical Approach Outline • • • • • • • • CT Dose Units Effective Dose Dose Reference Levels CT Dose Optimisation Techniques CT Dose Modulation Bismuth Shielding Breast Shields in Practice Summary CT Dose Units • CT Dose Index - measures Absorbed Dose in a CT phantom (mGy) • CTDIw = CTDI . tissue weighted factors • CTDIvol - weighted average of CTDI from within a phantom and corrected for pitch or table increment • DLP = CTDIvol (mGy) . L (mGy.cm) – Where L = Scan Length – Allows us to calculate Dose • Effective dose – Estimate of Stochastic Radiation Risk – Effective Dose (mSv) = DLP . CF – Where CF is the conversion factor from IRCP table – Takes Organ Sensitivity weighting factors into account 103 ICRP Tissue Weighting Factors Tissue Tissue Weighting ICRP 2007 Gonads 0.08 Bone Marrow (Red) 0.12 Colon 0.12 Lung 0.12 Stomach 0.12 Breast 0.12 Remainder 0.12 Bladder 0.04 Liver 0.04 Oesophagus 0.04 Thyroid 0.04 Skin 0.01 Bone surface 0.01 Brain 0.01 Salivary Glands 0.01 Total 1 ICRRP 103, 2008 Effective Dose Conversion Table Effective Dose = DLP . CF Body Region Conversion Factor (mSv mGy-1 cm-1) Head 0.0023 Neck 0.0054 Chest 0.017 Abdomen Pelvis 0.015 0.019 Ref. European Guidelines on Quality Criteria for Computed Tomography EUR 16262, May 1999 CT Radiation Sources 1% US Radiation sources to Population 3% 11% 26% 4% 55% Radon Other Natural Sources Medical X rays Nuclear Medicine Consumer Products Other From NCRP Report No. 93 CT is 13% of medical x-ray exams, but accounts for 70% of medical dose (Lee, 04) In Australia CT accounts for 50% of all medical radiation dose (0607) ARPNSA looking at establishing national DRLs DRL’s Dose Reference Level A reference level of dose likely to be appropriate for average sized patient undergoing medical diagnosis and treatment • DRLs allow us to: – – – – Compare CT dose in mSv with other Modalities Compare our practice with other centers Realise if we have a certain margin for Optimisation Detect abnormal situations with high radiological risk to the patient Establishing DRLs • How – Audit dose reports for range of body sizes of each scan type – Record DLP and CTDIvol – Employ your in house Physicist or Radiation Safety Officer to develop DRLs - third quartile values of CTDIvol and DLP • Published DRLs Reference – – – – NRPB data survey 1990 ACR Recommendations European Guidelines 16262 ICRP UK DRL Guide Examination Diagnostic Reference Level CTDI (mGy) DLP (mGy . Cm) Routine Head 60 1060 Face/Sinuses 35 360 Vertebral Trauma 70 460 Routine chest 30 650 HRCT 35 280 Routine Abdomen 35 780 Liver/Spleen 35 900 Routine Pelvis 35 570 Osseous Pelvis 25 520 Ref. European Guidelines on Quality Criteria for Computed Tomography EUR 16262, May 1999 US Typical Effective Radiation Dose Values CT Head CT Pelvis CT Liver CT Chest CT Abdopelvis CT Cardiac CT mSv 1-2 3-4 5-7 5-7 8-11 5-12 NON CT Hand X-ray Chest X-ray Mammogram Barium Enema Coronary Angio Sestamibi Scan mSv <0.1 <0.1 0.3-0.6 3-6 5-10 6-9 Mayo Clinic, 06 What should we be Doing? • Archiving Dose Reports • Employ Dose Reduction Techniques • Ask your Radiologist’s to Accept more Noise in your Images • Look at developing your own site related DRL’s Dose Optimisation Techniques • • • • • • • • Patient Positioning Scouts kV FOV and Filters Pitch Image Noise Rotation Time Dose Modulation Patient Positioning • Take the time to position the patient in isocentre • Use different tilt Positions when scanning the head • Reduces scan Volume • Ensure the patient is flat in the Z plane – This effects optimal dose modulation Positioning and Dose Modulation • Correct Alignment can reduce dose up to 56% (Banghart, 06) • Centered too high = Increased Dose • Centered too low = Reduced Dose and Increased breast dose Excessive dose Centering error Dose too low Tube Position for Scouts • Make sure that tube position is PA when scanning scouts • Reference vendor user guide to find out tube home position • Kv must be the same for the scout and scan acquisitions for optimal dose modulation kV • kV and Dose have an exponential relationship by a factor of 2 • Lower kV = better image contrast resolution • Generally standardised at 120 kV – Try using 100kvp for smaller patients on chest scans – Isolated Extremities can be scanned at 80-100kV – Cardiac Scan performed at 100kV for patients <180pds • Use 80- 100kV for Paediatrics • When kV is increased from 120 to 140kV = 39% dose increase FOV and Filters • Always choose the smallest FOV possible for the body part being examined • Use Appropriate Filters provided by vendor – Bow tie Filters can reduce skin dose by 50% – Reduce noise and Artifact • Use Paediatric Filters if Available • Post Processing Filters – Neuro – Cardiac Excessive dose Centering error Dose too low Ref: www.gehealthcare.org Pitch • Pitch = table increment per rotation /beam collimation • Inversely Proportional to patient dose • Larger Pitches – Lower Radiation Dose – Faster Scan times – More image Noise – Decreased Resolution • Paediatric scans should have pitch of 0.9-1.5 Image Noise • Noise is related to Dose Phantom B (40 mAs) Phantom A (80 mAs) A • Overcoming Noise B – Increase MPR Thickness – Use Post Processing Filters – Use Appropriate Algorithms • Ask Radiologists to accept more image noise Rotation Time • Rotation Time is related to dose in a linear fashion • Trade off with image noise • Shorter Rotation Time Advantages 0.4s RT (200mAs) – Linear decrease in dose – Faster scan time – Less motion/breathing artifact 1s RT (200mAs) • Use Short Rotation times for Paediatrics Dose Modulation • Scanner adjusts the Xray tube mA automatically with changes in patient anatomy during the scan and from patient to patient • Produces reduced dose scans without image quality compromise Ref. Radiographic Journal ,2006 Advantages of Dose Modulation • • • • • • • • More consistent signal to detectors Image quality is maintained at a constant level Tube Heat capacity conserved Reduction in (photon starvation) streak artefact Dose Optimisation Dose Reductions from 10-50% Able to set Reference or noise levels Some vendors allow you to cap a max and min mA Bismuth Shielding • Shielding that can be used on in plane MDCT scanning • Has been shown to reduce radiation dose to skin and superficial organs without compromising image quality • Reduces Primary beam Attenuation Ref. Medscape.com Bismuth Breast Shielding • Used to Reduce unwanted radiation to the breast without degrading image quality • Can reduce dose to breast from 43-73% for Thoracic scans Ref. Medscape.com Breast Shielding In Practice • Patient Selection – All Females of child bearing age ( <50yrs ) – Where the anatomical Thorax is being scanned • Shield Parameters – Attenurad Bismuth Shield 0.06mm Pb – 0.675cm offset – applied to each side – Covered in plastic for cleaning and reuse Breast Shielding Protocol • Shield Placement – Top of shield is placed on sternal notch to cover breasts – curve round auxilla – Shield is positioned after scouts have been performed The Resultant Images Other Bismuth Applications • Ask your Vendor if Bismuth Shielding is compatible with your scanner • Paediatric Breast Shielding • Thyroid and Eye Shield Ref. Impactscan.org Summary • • • • • • • • Know your CT dose Units Audit CT Doses Archive Dose Reports Think about possible site related DRL’s Review Dose Optimisation Techniques Use Dose Modulation where possible Ask your Radiologists to accept more image noise Use Shielding if available Any Questions?