وزارة التعليم العالي جامعة المجمعة كلية العلوم الطبية التطبيقية قسم علوم المختبرات الطبية Ministry of Higher Education Majmaah University College of Applied Medical Sciences Department of Medical Laboratory Lecture 8 Name of Instructor: Dr. Mosaab Omar Location: Majmaah male campus MCQ: Please find the proper answer of the following: Which of the following indicates a possible case of tuberculosis? (a) The presence of gram-negative cocci in the lung secretions of the patient. (b) The presence of gram-negative rods with bipolar staining in the lung secretions of the patient. (c) The presence of acid-fast rods in the lung secretions of the patient. (d) A positive Weil-Felix test. (e) A skin rash on the palms of the hands and soles of the feet. The tubercles of tuberculosis (a) are pockets of fibrous connective tissue, containing live Mycobacterium tuberculosis, that form in the lungs of tuberculosis patients. (b) form in the lungs of tuberculosis patients because phagocytosis is ineffective in killing Mycobacterium tuberculosis, causing the body to respond by secreting fibrous connective tissue. (c) may rupture and release active Mycobacterium tuberculosis into the lungs, causing a recurrence of the infection months or years after the initial exposure. (d) Both (a) and (b) are true, but (c) is false. (e) (a), (b) and (c) are all true. 1 A group of bacteria that are classified with other Gram-positive bacteria on the basis of their cellular architecture, but they possess a very waxy cell wall, and they rarely stain using conventional protocols such as the Gram stain. Genus Clostridium Propionibacteria Lactobacilli Mycobacteria Enterobacteria Tuberculosis is transmitted through: A: Infected water B: Infected hands C: Infected blood D: Infected air Which of the following statements is incorrect: A: People who are exposed to TB may or may not develop TB infection B: People with TB infection may or may not develop TB disease C: risk of developing TB disease is highest in first 2 years after infection D: Every individual exposed to TB develops disease Which one of the following are constituent of Lowenstein Jensen media except: 2 A. Agarose B.Malachite gree C. Mineral salts D. Asparagine Following are the first line antitubercular drugs except: A. isoniazid B. rifampin C. PAS D. streptomycin Which one of the following anti-tubercular drugs acts best in acidic pH: A. INH B. Pyrazinamide C. Streptomycin D. Rifampicin Which of the following statements is incorrect: A. Mycobacteria are obligate aerobes B. Increased CO2 tension enhances growth C. Can not grow in cell free media D. Doubling time of tubercle bacilli is about 18 hours. 3 Which one of the following bacteria contains mycolic acid in the cell wall A. Escherichia B. Mycoplasma C. Mycobacteria D. Staphylococcus Method of testing resistance to drugs in TB are all except A. Radiometric broth method B. Molecular method C. Disk diffusion method D. PCR Mycoplasma pneumonia is characterised by all except – A. Diagnosed by serum cold abntibody B. Treatment is erythromycin C. Cannot be cultured from sputum D. Raised ESR All the following are true of Tuberculosis except A. For sputum to be positive,bacilli should be > 104 /ml B. Niacin test differentiates M. tuberculosis and M.bovis C. Pathogenicity to rabbits differentiates M. tuberculosis and M.bovis 4 D. Culture techniques have low sensitivity Drug resistance in tuberculosis is due to A. Transformation B. Transduction C. Conjugation D. Mutation Most common agent causing tuberculosis in AIDS patient in tropical countries is : A. Mycobacterium parvum B. Mycobacterium atypical C. Mycobacterium tuberculosis D. Mycobacterium intracellulare The medium used for Mycobacterium tuberculosis is A. Sabouraud's medium B. L J medium C. Pick's medium D. NIH medium Collection of urine sample of a patient of TB/kidney is done: 5 A. 24 hrs urine B. 12 hrs urine C. In early morning D. Any time All the following are the most common nosocomial infections except: A. Staph aureus B. P.aeruginosa C. Enterobacteriaceae D. Micobacterium 1- 6