وزارة التعليم العالي جامعة المجمعة كلية العلوم الطبية التطبيقية قسم علوم المختبرات الطبية Ministry of Higher Education Majmaah University College of Applied Medical Sciences Department of Medical Laboratory Lecture 5 Name of Instructor: Dr. Heavin Hannan Location: Majmaah female campus MCQ: Please find the proper answer of the following: 1. Leishmania tropica causes: a. kala azar b. oriental sore c. espundia d. chiclero's ulcer 2. The fever associated with visceral leishmaniasis may resemble that of a. Cutaneous leishmaniasis. b. Oriental sore. c. Malaria. d. Drug sensitivity 3. After a sand fly has ingested macrophages containing the amastigotes of Leishmania, which of the following events takes place? a. The amastigotes go through a series of divisions culminating in the production of metacyclic trypomastigotes. b. The amastigotes fuse and undergo a type of sexual reproduction. c. The amastigotes multiply until they block the sand fly pharynx. d. The amastigotes transform into infective metacyclic promastigotes that invade through the gut wall and move to the salivary glands from which they are ingested the next time the sand fly feeds. e. The amastigotes transform into the procyclic promastigote stage. 4. The life cycle of which is vector transfer: a. Entamoeba histolytica b. Leishmania donovani c. Giardia lamblia d. Balantidium coli e. Trichomonas vaginalis 5. The amastigote of Leishmania donovani mainly parasitize in a. the a karyocyte of human 1 b. the neutrophil of human c. the stomach of Phlebotomus chinensis d. the macrophage of human e. the acidophil of human 6. The main reason to cause kala-azar patients’ anaemia is a. haematogenesis dysfunction of bone marrow b. polypide damaging akaryocyte c. hyperfunction of spleen d. the decrease of protein synthesis e. immune hemolysis 7. The stage that Leishmania infect people is a. mature cyst. b. gametocyte c. amastigote d. trophozoite e. promastigote SAQ 1. Explain the difference between cutaneous and visceral Leishmaniasis. 2. What has been done to control the spread of Leishmania spp? Name of Instructor: Dr. Mosaab Omar Location: Zulfi campus MCQ: 1- Leishmania is transmitted by……………….. a- Sexual contact b- Ingestion of the cyst c- biting of Sand fly d- none of them 2- Leishmania clinical disease present in different forms which are: a- Visceral leishmaniasis b- Cutaneous leishmaniasis c- Mucocutaneous leishmaniasis d- All of them 2 3- Dum dum fever (Kala azar gever) is caused by …………… a- Leishmania tropica b- Leishmania donovani c- Leishmania mexicana d- Leishmania braziliensis 4- The Drug of choice in treatment of Leshmania donovani is…… a- sodium stibogluconate b- Flagyl c- Penicilline d- Ivermectin 5- The urban cutaneous leishmaniasis is caused by: a- L. tropica minor b- L. tropica major c- L. aethiopica d- L. donovani SAQ: 1. Clinical signs of different Leshmania species affecting Human 2. Laboratory diagnosis of Visceral Leishmaniasis 3