26388.doc

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Step 1
Profile of Pap smear cytology in the Western region of
Saudi Arabia.
OBJECTIVE: Cervical carcinoma is an important women's health problem in the
Western countries. There are only few published data on this disease in the
Kingdom of Saudi Arabia (KSA). The aim of this study is to evaluate the abnormal
cytological entities detected by cervical Pap smear in Western region of KSA and
to discuss the importance of Pap smears screening programs. METHODS:
Retrospective review of all the cervical smears present at the King Abdul-Aziz
University Hospital, Jeddah, KSA from 1984 to 2000. The reports of 22089
smears were retrieved from the file of the pathology department. RESULTS:
There were 368 (1.66%) abnormal Pap smears out of 22089 smears. Out of these
368 abnormal Pap smears there were 62 (16.8%, mean age 37 year) cervical
intraepithelial neoplasia grade 1, 45 (12.2%, mean age 38.5) cervical
intraepithelial neoplasia grade 2, 27 (7.3%, mean age 40.5) cervical intraepithelial
neoplasia grade 3, 22 (6%, mean age 38.5) positive for malignant cells, 36 (9.8%,
mean age 40.5) atypical endocervical cells, 88 (23.9%, mean age 39) atypical
squamous cells, 9 (2.4%, mean age 40.5) squamous metaplasia with atypia, 26
(7.1%, mean age 45) squamous cell carcinoma, 6 (1.6%, mean age 36.5)
reparative atypia, 2 (5.4% mean age 35) herpes virus changes, 19 (5.1%, mean
age 37.5) human papilloma virus changes, 5 (1.4%, mean age 55)
adenocarcinoma of endometrium, and 7 (1.9%, men age 43.5) adenocarcinoma
of endocervix. CONCLUSION: Cervical intraepithelial neoplasia and invasive
cervical carcinoma are less common in KSA compared to the Western countries,
however, cervical screening programs are necessary nationwide to estimate the
actual magnitude of cervical carcinoma and its precursor lesions.
PMID: 14647558 [PubMed - indexed for MEDLINE]
Saudi Med J.
‫عنوان الوثيقة‬
Document (
)Title
‫المستخلص‬
)Abstract(
)ISSN( ‫ردمد‬
‫اسم الدورية‬
)Journal Name(
24
)Volume( ‫المجلد‬
11
‫العدد‬
)Issue Number(
2003 Nov
1225-9
‫سنة النشر‬
Publishing (
)Year
‫الصفحات‬
)Pages(
Step 2
Jaudah
Al-Maghrabi
Department of Pathology, King Abdul-Aziz University Hospital, Jeddah,
Kingdom of Saudi Arabia.
jalmaghrabi@hotmail.com
‫االسم األول للباحث‬
First name of the
researcher
‫االسم األخير للباحث‬
Last name of the
researcher
‫العنوان‬
)Address)
‫االيميل‬
) E-mail (
Step3
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