Complications can be divided into the General complications of any operation Specific complications of individual operations According to time of occurance Immediate (during operation or within the next 24 hours). Early postoperative (during the first postoperative week). Late postoperative (up to 30 days after operation) and long-term 26/09/1437 2 Principal categories of surgical complications 1. Complications predisposed to by intercurrent ‘medical disorders, e.g. ischaemic heart disease, chronic respiratory disease or diabetes mellitus. 2. Complications of anesthesia 3. General complications of operations, e.g. haemorrhage or wound infection. 4. Complications of any surgical condition, e.g. pulmonary embolus, chest or urinary tract infection. 26/09/1437 3 2. Complications of anesthesia 1. Injection site - pain, hematoma, delayed recovery of sensation (direct nerve trauma), infection Systemic effects of local anesthetic agent *allergic reactions (very rare). *Toxicity due to either excess dosage, or inadvertent intravenous injection. Toxic effects include: dizziness, tinnitus. nausea and vomiting, bradycardia 26/09/1437 4 * Failure of anesthetic ( anatomical difficulties or technical failure). * Headache or minor intrathecal haemorrhage. * Intra-thecal bleeding *In spinal anesthesia, if the anesthetic agent flows too far proximally, respiratory paralysis may occur. *Permanent nerve or spinal cord damage - injection of incorrect drug. *Paraspinal infection - introduced by the needle. *Systemic complications (severe hypotension or postural hypotension). 26/09/1437 5 : *Direct trauma to, mouth or pharynx, General e.g. teethanesthesia: *allergic reactions to anesthetic agents: *Minor effects, e.g. postoperative nausea and vomiting. *Major effects: e.g. cardiovascular collapse *Inadvertent trauma: *Slow recovery from anesthetic *Hypothermia 26/09/1437 6 COMPLICATIONS OF ANAESTHESIA DROWSINESS PAIN AND DISCOMFORT NAUSEA AND VOMITING CHEST INFECTION DEEP VEIN THROMBOSIS 26/09/1437 7 3. GENERAL COMPLICATIONS OF OPERATIONS The main complications of any operation are hemorrhage, infection, delayed wound healing, surgical damage to related structures and inadvertent trauma to the patient in theatre. 1. HAEMORRHAGE Pre- operative Hemorrhage: Hemorrhage occurring during an operation (primary haemorrhage) should be controlled by the surgeon before the operation is completed. 26/09/1437 8 3. GENERAL COMPLICATIONS OF OPERATIONS 2. Early Postoperative Hemorrhage: Hemorrhage during the immediate postoperative period usually indicates inadequate operative haemostasis or unrecognized trauma to a blood vessel. After major blood loss requiring large volume transfusion of stored blood. 3. Later Postoperative Hemorrhage Hemorrhage occurring several days after operation is usually related to infection which erodes vessels at operation site; this is known as secondary hemorrhage. Treatment involves managing the infection, but exploratory operation is often required to legate bleeding vessels. 26/09/1437 9 3. GENERAL COMPLICATIONS OF OPERATIONS 2. INFECTION RELATED TO THE OPERATION SITE: 1. Minor Wound Infections: The most common operative infection is a superficial wound infection occurring within the first postoperative week. This relatively trivial infection presents as localized pain, redness and a slight discharge. The organisms are usually staphylococci or streptococci derived from the skin. 26/09/1437 10 3. GENERAL COMPLICATIONS OF OPERATIONS 2. Wound Cellulites and Abscess: More severe wound infections occur most commonly after bowel-related surgery. often after the patient has left hospital. These infections commonly present first with a pyrexia; examination of the wound reveals either a spreading cellulites or localized abscess formation. Cellulites is treated with appropriate antibiotics. 26/09/1437 11 3. LATE INFECTIVE COMPLICATIONS A late infective complication of surgery is a chronically discharging wound sinus which emanates from a deep chronic abscess. It usually relates to foreign material such as a nonabsorbable suture or mesh or sometimes necrotic fascia or tendon. These sinuses commonly follow wound infections where healing is delayed and incomplete. 26/09/1437 12 3. IMPAIRED HEALING Factors Retarding Wound Healing: Wound healing in general is retarded if blood supply is poor (as in arterial insufficiency) or if the wound is under excess suture tension. Other Factors which may retard wound healing are long-term steroid therapy, immunosuppressive therapy, previous radiotherapy, severe rheumatoid disease, malnutrition and vitamin deficiency, especially of vitamin C. 26/09/1437 13 4. Incisional Hernia Incisional hernia is a late complication of abdominal surgery. These hernias usually become apparent within the first postoperative year but sometimes develop as long as 5 years later; the overall incidence is about 10-15% of abdominal wounds. The hernia is caused by breakdown of the repair to the abdominal wall muscle and fascia. 26/09/1437 14 4. Incisional Hernia Predisposing factors are abdominal obesity, distension and poor muscle quality, poor choice of incision, inadequate closure technique, post-operative wound infection and multiple operations through the same incision. 26/09/1437 15 5. SURGICAL INJURY 1. Unavoidable Tissue Damage: Anatomical structures, particularly nerves, blood vessels and lymphatics, may be unavoidably damaged during operation. This is particularly true in cancer surgery, illustrated by facial nerve damage during total parotidectomy. 2. Inadvertent Tissue Damage: Structures may be inadvertently damaged during operation. Examples include recurrent laryngeal nerve damage during thyroidectomy and trauma. 26/09/1437 16 5. SURGICAL INJURY 3. INADVERTENT OPERATING THEATRE TRAUMA Injuries resulting from falls from trolleys or operating table during, positioning. Injury to diseased bones and joints from manipulation or positioning.. Ulnar and lateral popliteal nerve palsies. Electrical burns from wet or poorly contacting diathermy pads. Excess pressure on the calf causing deep venous thrombosis. Excess heel pressure causing pressure sores. Cardiac pacemaker disruption by diathermy equipment 26/09/1437 17 COMPLICATIONS OF ANY SURGICAL CONDITION 1. RESPIRATORY COMPLICATIONS: Up to 15% of patients suffer from respiratory complications associated with general anesthesia and major operations. The most common of these are atelectasis, pneumonia. Effects of Anaesthesia and Surgery on Respiratory Function: Anesthesia and surgery predispose to post-operative complications by altering lung function and compromising normal defense mechanisms as follows: 1. Lung tidal volume may be reduced by as much as 50%, depending on the incision site. Thoracic, upper abdominal and lower abdominal incisions (in decreasing order of effect) particularly reduce, lung volume 26/09/1437 18 COMPLICATIONS OF ANY SURGICAL CONDITION Effects of Anaesthesia and Surgery on Respiratory Function: 2. Lung expansion is reduced by the supine posture during and after operation, pain, abdominal distension, abdominal constriction by bandages and the effects of sedative drugs. 3. Diminished ventilation and pulmonary perfusion result in reduced gaseous exchange. 4. Airway defenses are compromised by loss of the cough reflex and diminished ciliary activity, which both lead to accumulation of secretions. 26/09/1437 19 COMPLICATIONS OF ANY SURGICAL CONDITION 2. Atelectasis: Pathophysiology and clinical features: Atelectasis or alveolar collapse occurs when airways become obstructed and air is absorbed from the air spaces distal to the obstruction. Bronchial secretions are the main cause of this obstruction. Predisposing factors include shallow ventilation, loss of periodic hyperinflation, inhibition of coughing and pooling of mucus. All of these are particular problems after thoracic and upper abdominal surgery. 26/09/1437 20 COMPLICATIONS OF ANY SURGICAL CONDITION Prevention and treatment of atelectasis: Atelectasis is best prevented by preoperative and postoperative physiotherapy for patients undergoing major surgery. This includes deep breathing exercises, regular adjustments of posture and vigorous coughing. During physiotherapy, wounds should be supported by the patient’s hand. 26/09/1437 21 COMPLICATIONS OF ANY SURGICAL CONDITION 5. THROMBOEMBOLISM Pathophysiology Venous thromboembolism is a major cause of complications and death after surgery or trauma. Venous blood is normally prevented from clotting within the veins by a complex series of mechanisms which include local inhibition of the clotting cascade, prompt lysis of small clots that do form, and continues flow of blood. 26/09/1437 22 COMPLICATIONS OF ANY SURGICAL CONDITION 5. THROMBOEMBOLISM Predisposing factors for deep vein thrombosis and pulmonary embolism *Trauma and surgery (complex systemic effects) *Direct trauma to the pelvis and lower limbs, especially fractures *Previous venous thromboembolism *Pre-existing lower limb venous disorder causing stasis *Venous stasis during general or regional anesthesia (loss Of calf muscle pump and postural pressure on the calves) 26/09/1437 23 COMPLICATIONS OF ANY SURGICAL CONDITION 5. THROMBOEMBOLISM Predisposing factors for deep vein thrombosis and pulmonary embolism Malignant disease Immobility. e.g. bedbound patients after operation or stroke Cardiac failure High- estrogen, oral contraceptive piles, estrogen treatment Pregnancy Pelvic masses Obesity Dehydration 26/09/1437 24 COMPLICATIONS OF ANY SURGICAL CONDITION DEEP VEIN THROMBOSIS Deep vein thrombosis in the lower limbs (DVT) is often silent with the classic clinical features found in only half the cases. These include swelling of the leg, tenderness of the calf muscles, increased warmth of the leg, and calf pain on passive dorsiflexion of the foot (Homan’s sign). The presence of these features indicates that venous occlusion has extended at least as far as the popliteal veins. 26/09/1437 25 COMPLICATIONS OF ANY SURGICAL CONDITION DEEP VEIN THROMBOSIS Occlusion of the ilio-femoral veins tends to produce diffuse and sometimes massive swelling of the whole lower limb. In addition, there is tenderness over the femoral vein in the groin. In severe cases, the leg becomes painful and white boggy with edema. 26/09/1437 26 COMPLICATIONS OF ANY SURGICAL CONDITION Pulmonary embolism The classic picture of pulmonary embolism (PE) is sudden dyspnoea and cardiovascular collapse, followed by pleuritic chest pain, development of a pleural rub and haemoptysis. ECG may show evidence of right heart strain. Prevention of Venous Thromboembolism These include early postoperative mobilization, adequate hydration and avoiding calf pressure. For patients at higher risk, specific prophylactic measures should be taken to reduce the risk of deep venous thrombosis (and consequent pulmonary embolism). 26/09/1437 27 COMPLICATIONS OF ANY SURGICAL CONDITION Prophylactic measures include the following: 1. Low-dose subcutaneous heparin. 2. Calf compression devices - several pneumatic and electrical devices are available for intra-operative calf compression to simulate normal muscle pump activity. These have the advantage of being non-invasive and easily applied to all patients, even those at low risk, but their efficacy is less than low dose heparin 3. Graded-compression “anti-embolism’ stockings They offer a suitable level of prophylaxis for patients at low or moderate risk. The stockings must be worn during operation as well as during the early postoperative period. 26/09/1437 28 COMPLICATIONS OF ANY SURGICAL CONDITION PRESSURE SORES: Pathophysiology: Elderly, debilitated and other bed-bound patients are extremely susceptible to pressure sores (bed sores), particularly over bony prominences such as the sacrum and heels. Diminished protective pain response plays an important part. Tissue necrosis and subsequent failure to heal result from a combination of factors including recurrent pressure ischemia, poor tissue perfusion and malnutrition. 26/09/1437 29 COMPLICATIONS OF ANY SURGICAL CONDITION Prevention and management of pressure sores: Relieving pressure on the heels Regular change of posture - for most patients, this involves encouragement to get out of bed, at least into a bedside chair, and to mobilize beyond this as much as possible. Regular checking of pressure areas and local massage. Management of incontinence 26/09/1437 30 26/09/1437 31