MANAGEMENT OF BURNS MEDICAL & SURGICAL PHT 331 – 1435 -1436H – 1st SEMESTER Lecture Outline 2 This lecture deals about the medical & surgical aspects of the burn. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 Lecture Objective 3 At the end of this lecture, the student will able to; Explain the management of first aid, Emergency care, Modern burn care, Burn wound healing, Medical & surgical management. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 FIRST AID 4 • A friend, relative or stranger may rescue the victim of a serious burn accident. The decisions made and the treatment given at the scene of the accident – especially the quality of the first aid - has often had a profound effect on mortality and morbidity (British Burns Association 2001, p. 17). Flame burns must be smothered. Cold water applied continuously over the burnt area relieves pain and limits the depth of the burn PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 5 CHEMICAL BURNS contaminated clothing must be removed and copious quantities of running water applied to the area. Neutralizing agents need to be identified and applied accordingly. SCALDS cold water can limit the extent of the damage and reduce the pain. ELECTRICAL BURNS, the patient may require CPR before attention can be paid to the injury. Unlike heat burns, these injuries do not spread and it is sufficient to cover the area with a clean cloth that has been soaked in clean cold water PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 6 MINOR BURNS These are defined as less than 10% surface area in a child or less than 15% in an adult. If the injury is noncomplex these injuries are cleaned with chlorhexidine and covered with a bactericidal non-stick dressing. The patient can rest at home and, depending on local circumstances,the dressings are changed every 2-3 days. MAJOR BURNS These are injuries that involve 10% or more of the body surface area in children and 15% or more in an adult. If the injury is complex the patient will be admitted to the burns unit or intensive care unit PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 7 First aid and Emergency treatment of burned patients The main aims of this stage are : removal of victim from fire or agent check airway evaluation of associated injuries Initiation of resuscitation PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 8 Remove the victim from the fire Wrapping patient in a clean sheet or blanket Rolling the in on the ground or immersion into lake or river are not recommended because of possibility of massive contamination. Remove the victim from contact with electricity either by disconnecting the source or by using a non conductor to move the victim from the point of contact. Irrigating the affecting area with water( cold water for a period 15-20 min). in case of chemical burn PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 9 N.B. The use of cold water to Decrease pain Decrease inflammatory response Decrease exudation PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 10 Check the airway Insertion of oropharangeal airway, if the patient is unconscious and the tongue appears to be obstructing airway. Insertion of an endotracheal airway in upper airway obstruction cases. Evaluation of associated injuries: Rapid check of patient's thorax, upper and lower limbs and abdomen. Observe fractures and dislocations. Lock for head injuries. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 11 Initiation of resuscitation and transportation Resuscitation <20% oral fluid 20-50 % I.V. lines in un burned area 50-60 % or more two I.V. lines in burned and non burned Transportation The patient should be transported to the nearest medical facility PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 12 Management in emergency room and triage Check airway and vital signs Re-evaluate the presence or absence of associated injuries. Evaluate total burn size Triage. Triage: Decision making with regard to admission or discharge PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 13 Indications of some cases that need admission to hospital Burn larger than 15% of total body surface in adult or 10 % in children All burns which have a third degree. Burns of face, hands and perineum. All electrical and chemical burn. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 Modern burn care 14 Modern burn care may be divided into the following 4 general phases: The first phase, initial evaluation and resuscitation, occurs on days 1-3 and requires an accurate fluid resuscitation and thorough evaluation for other injuries and comorbid conditions. The second phase, initial wound excision and biologic closure, includes the maneuver that changes the natural history of the disease. This is accomplished typically by a series of staged operations that are completed during the first few days after injury. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 15 The third phase, definitive wound closure, involves replacement of temporary wound covers with a definitive cover; there is also closure and acute reconstruction of areas with small surface area but high complexity, such as the face and hands. The final stage of care is rehabilitation, reconstruction, and reintegration. Although this begins during the resuscitation period, it becomes time-consuming and involved toward the end of the acute hospital stay. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 BURN WOUND HEALING 16 EPIDERMAL HEALING: Occur on the surface of the wound The intact epithelium attempts to cover an exposed wound through ameboid movement of cell from basal layer of surrounding epidermis into wound. The epithelial cells stops migration when they are completely in contact with other epithelial cells. After this contact inhibition - cells can begin to divide and multiply through mitosis. Dryness is common PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 DERMAL HEALING 17 Scar formation occurs Divided in to 3 phases:Inflammatory,Proliferative,Maturation INFLAMMATORYPHASE: begins at time of injury ends in 3-5days.Characterized by inflammatory reactions redness,warmth,edema,pain,decreased ROM. Initially there is decreased blood flow,platelets aggregate and Fibrin is deposited. Later Vasodilation occcurs, leukocytes infilterate ,presences of macrophages,attracts Fibroblast. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 18 PROLIFERATIVE PHASE: Re-epithelialization occurs at the surface In deep wound Fibroblast migrates ,which synthesis Scar tissue. During this period of Fibroplasia, the tensile strength of the wound increases at a rate proptional to the rate of collagen synthesis. Wound contraction occurs PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 19 MATURATION PHASE Reduction in the number of Fibroblast Remodeling of collagen Collagen becomes more parallel in arrangements and forms stronger bonds If rate of collagen production exceeds breakdown then hypertrophic scar may result. Keloid is large firm scar that overflows the boundaries of original wound. It may lead to Functional and cosmetic deformities PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 PHASES OF WOUND HEALING 20 PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 HEALING OF WOUND 21 PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 MEDICAL MANAGEMENT 22 • EARLY HOSPITAL MANAGEMENT (INCLUDING THE SHOCK PHASE). Maintenance of a clear airway pain relief Assessment of TBSA Maintenance of fluid balance Removal of adherent clothing covering of the Burns with sterile cotton dressings Reassurance and explanation to the patient Transfer to a burns unit or admission to an intensive care unit. (Whether the person is sent to the operating theatre for shaving of burns and grafting depends on the depth of the burns, the age of the patient and whether the patient is fit for surgery.) PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 23 Resuscitation Fluid replacement is administered over a 36-hour period (from the occurrence of the burn, not the time of arrival at hospital). The volume of plasma required by the burns patient is related to the TBSA and the size of the patient (Evans et al. 1952; cited by Settle 1986, p. 14). To calculate the volume of fluid required for resuscitation, the following formula is used (Muir and Barclay 1962): mL of plasma = TBSA x age of patient. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 24 Management of wound areas varies according to the experience of the staff and facilities available. The two main themes are 'open' or 'closed'. OPEN METHOD This method leaves the wound exposed. If exudate is cleaned away regularly, the area dries out. Bacterial growth is inhibited and this method is used for areas that are difficult to dress, such as the face. Healing of the epithelium tends to be slower than with the closed method. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 25 CLOSED METHOD The primary layer of dressing is non-adherent, for example petroleum jelly gauze. This is then covered with layers of absorbent cotton gauze ,held in place by crepe bandages or net. With bandages securing the dressings the patient may be able to begin to mobilise about the ward with the aid of the physiotherapist. Silver sulfadiazine is commonly used. When a hand is affected, a polythene bag containing chlorhexadine may be placed over the hand and bandaged to the forearm. The patient is able to regularly exercise the hand freely through full range of motion.The bag is changed daily or more frequently if indicated by large amounts of exudate collecting in the bag.The bag is changed to dry dressings at the nurse's discretion. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 CLOSED METHOD 26 PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 SURGICAL MANAGEMENT 27 ESCHARECTOMY It is surgical removal of the dead, burnt skin by a method of excision or shaving. SKIN GRAFTING involves covering the open tissues with a layer of split skin. Z- PLASTY Surgical correction of Scar contracture. It serves to lengthen a scar by interposing normal tissue in the line of the scar. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 ESCHARECTOMY 28 PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 Z-PLASTY 29 PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 SKIN GRAFTING 30 Grafting is the closure of a burn wounds with skin tissue. The closure may be temporary or permanent depending on the tissue chosen. involves covering the open tissues with a layer of split skin. Skin graft: It is nonvascular skin transfers may be divided into two groups. A) Split-thickness skin graft. B) Full-thickness skin graft Grafts are kept in position with petroleum jelly gauze and bandages, and splints can be applied to immobilise the joints adjacent to the grafts Skin is usually removed with a dermatome PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 31 Indications for Skin Grafts: 1) To achieve temporary cover A) Close an open wound B) Prevent infection C) Hasten initial healing D) Prevent exposure of underlying structures 2) For definitive cover: A) Provide permanent skin replacement which is supple sensate and durable. B) to resurface areas of scarring or contracture. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 Types of skin graft 32 1. Auto graft: It is skin transferred from one - area of the body to another. This should provide permanent cover. 2. Allograft (homograft): It is skin from another human (possibly a cadaver) is used. This provides only temporary cover until an autograft is available. 3. Xenograft (heterograft): This uses animal (e.g.) pig skin or porcine and is also only a temporary cover (donor- site). N.B. - The most common way to close a deep burn wound after removal of eschar is with the use of non vascular skin transfers PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 33 A) A split - thickness skin graft (STSG): Include the epidermis and any portion of the dermis. - The Donor sites of the split thickness skin graft are generally obtained from the thigh, buttock, or abdomen. B) Full thickness skin graft (FTSG): Includes the epidermis and entire dermis. All subcutaneous fat is removed from the dermis to improve the survival of the graft. - The Common donor site includes the groin and the medial aspect of the arm because the residual scar is hidden. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 SPLIT THICKNESS GRAFT 34 PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 FULL THICKNESS GRAFT 35 PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 36 SHEET GRAFT{ Skin is applied without alteration following harvesting from donor site usually in face,neck,hand} MESH GRAFT – When limited skin is available ,meshing of a graft consist of processing sheet graft that makes tiny parallel incision in a linear arrangement.This process permits Skin graft to be expanded before applying. Allow coverage of large area.Skin graft is held by sutures,staples, steri-strips. Pressure dressing facilitates DONOR SITE site where skin is taken{Thigh,Buttocks,back PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 MESH GRAFT 37 PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 SHEET GRAFT 38 PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 39 Advantages of non vascular graft: 1 - Include a large supply of donor areas. 2- Ease of harvesting. 3-Reusable donor sites. 4- Decreased primary (early) contracture. 5- And the ability to cover large surface areas PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 40 Disadvantages of non vascular graft: 1- Bad cosmetic appearance . 2-Decrease durability. 3- Hyper pigmentation. 4- Increase secondary (or late) contracture. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 41 (1) The split thickness graft undergoes secondary (Late) contracture when it contracts as it heals, pulling the wound margins inward. (2) Both Types of grafts can be held in place with sutures, staples, or tape. (3) Meshing the graft is helpful in improving survival where moderate serous drainage is expected. (4) Where grafts may be exposed to shear forces, "tie - voer" dressing are useful. (5) Donor Site: Skin harvesting from the scalp in children can be recommended as first choice. The Advantages, especially the rapid epithelialisation and the lack of visible scars, over come the problems and the risks . PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 Healing of skin Grafts: 42 The healing skin grafts can be divided into three phases. 1. The first phase: the phase of serum imbibition begins immediately ,after placing the graft on the wound bed. Because there are no vascular connections, nutrients fluid supplied by diffusion of serum from the bed. The graft is held in place only by weak fibrin and fibronection bonds. 2. Second phase: at 24-48 hours new capillaries start invading the skin graft making the phase of revascularization. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 43 3. Third phase: the phase of organization starts at 4-5 days when collagen linkages are made between the wound bed and the graft to create firm attachments. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 44 Factors Affecting Wound Healing: 1. Age: affects wound repair. The rate of healing appears to slow with increasing age. 2. Infection: infection lead to healing failures. 3. Nutritional factors; nutrition is of extreme important factor for wound healing. 4. Vitamins: vitamins are important for normal tissue repair as vitamin C, A, E, B, (Thiamine) and B2 (pantothenic acid). PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 45 Trace elements are metals: that are needed for enzyme function. As iron zinc, copper, manganese calcium, and magnesium. Shortages in trace elements may contribute to impair healing. 6. Oxygen: Adequate blood supply is essential for healing. Oxygen is required to supply the energy for high metabolic needs healing wound. Poor vascularity essentially translates into hypoxia. 7. Diseases causing impaired wound healing: Diabetes altered healing. Chronic renal failure and liver failure lead to impaired healing Malignancy lead to healing abnormalities PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 46 8. Other causes of impaired healing: Steroids drugs altered healing. Chemotherapy agents lead to impair healing. Radiations Drug that alter immune system PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 47 Complications of skin grafts: Wound problems due to grafting on an inadequately prepared or unsuitable bed. A vascularity. Infection. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 48 Graft problems: Early: Inadequate fixation (shearing) Haematoma Failure of take/graft lysis due to infection Late: Failure of take due to inadequate contact between graft bed. Avoidable scarring/contracture Excessively expanded mesh graft Graft insensate Graft too thin for permanent cover Donor Site Problems: Failure to heal Infection PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016 SURVIVAL OF SKIN GRAFT 49 CIRCULATION: Provides a nutritive supply to graft INOSCULATION: Process by which direct connection is established between a graft and host vessels( within72 hours) PENETRATION of the host vessel into graft site Initially , structural connections are Fibrous, Collagen is then laid down to secure the attachment of the graft. PHT 331 – 1435 -1436H – 1st SEMESTER 7/1/2016