Lecture 2: Spirometer Introduction Spirometry is the gold standard for COPD (Chronic obstructive pulmonary disease) diagnosis Underuse leads to inaccurate COPD diagnosis Widespread uptake has been limited by: Concerns over technical performance of operators Difficulty with interpretation of results Lack of approved local training courses Lack of evidence showing clear benefit when spirometry is incorporated into management 2 Introduction What is Spirometry? Spirometry is a method of assessing lung function by measuring the volume of air the patient can expel from the lungs after a maximal expiration. 3 Introduction Why Perform Spirometry? Measure airflow obstruction to help make a definitive diagnosis of COPD Confirm presence of airway obstruction Assess severity of airflow obstruction in COPD Detect airflow obstruction in smokers who may have few or no symptoms Monitor disease progression in COPD Assess one aspect of response to therapy Assess prognosis (FEV1) in COPD Perform pre-operative assessment 4 Respiratory system Respiratory system functions include gas exchange, pH regulation, vocalisation, and protection from foreign substances. Respiration: o Cellular respiration is the cellular mechanism of energy conversion. o External respiration is the exchange of gases between atmosphere and cells. Includes ventilation, gas exchange at lungs and cells, and transport of gases in the blood 5 Respiratory controls Local controls o ↑ blood CO2 = dilation of bronchioles o ↑ alveolar O2 = vasodilation of bronchioles Neural Controls o Respiratory center in brain o Stretch receptors 6 Static lung volumes and capacities 7 Static lung volumes and capacities Dead space: the part of each breath that remains in the upper respiratory tract does not exchange. 8 Static lung volumes and capacities 9 Dynamic Lung Volumes 10 Calculating FVC P. Jamel A. SMIDA AJZ 205 “MECHANICAL MEDICAL DEVICES” 11 Calculating FEV1.0 P. Jamel A. SMIDA AJZ 205 “MECHANICAL MEDICAL DEVICES” 12 Calculating FEF25-75 P. Jamel A. SMIDA AJZ 205 “MECHANICAL MEDICAL DEVICES” 13 Other volumes & capacities Minute Respiratory Volume (MRV): quantity of air moved into and out of the lungs in one minute (TV x Respiratory rate) Maximal Ventilatory Volume (MVV): Maximal amount of air that a person can breathe in or out in a short period of time, typically 10, 12, or 15 secs Ventilation rate 14 Spirometers Apparatus used to: Measure static & dynamic lung volumes/capacities using a closed system Registers the amount and rate of air moved into or out of the lungs Two main types: 1. Volume: records the amount of air exhaled or inhaled within a certain time 2. Flow: measures how fast the air flows in or out as the volume of air inhaled or exhaled increases 15 Types of Spirometers Bellows spirometers: Measure volume; mainly in lung function units Electronic desk top spirometers: Measure flow and volume with real time display Small hand-held spirometers: Inexpensive and quick to use but no print out 16 Types of Spirometers Volume Measuring Spirometer 17 Types of Spirometers Flow Measuring Spirometer 18 Types of Spirometers Desktop Electronic Spirometer 19 Types of Spirometers Small Hand-held Spirometers 20 Volume Measuring Spirometer 21 Volume Measuring Spirometer Real time tracings record volume in relation to time 22 Volume Measuring Spirometer Advantages Some are portable versions Leak tests and calibrations are easy to perform Many can produce flow/volume curves and loops with the addition of special electronic or digital circuitry. Volume spirometers hold their calibration months to years better than flow spirometers 23 Volume Measuring Spirometer Disadvantages Not practical by hand to determine peak expiratory flow or instantaneous volumes, Coughs and submaximal efforts are not as obvious Some are heavy, cumbersome and may be prone to fostering mold or bacterial growth if not cleaned properly 24 Flow Measuring Spirometer 25 Flow Measuring Spirometer Measure how quickly air flows past a detector and then derives the volume by electronic means. Records flow rate at brief intervals (30-300x/sec) and use data to reconstruct the flow rate at each point in time and volume (digitization). Tracings measure flow in relation to volume 26 Flow Measuring Spirometer Advantages Computer can produce volume-time tracings Tend to be lighter and more portable Disposable, single-use flow sensors, available on some flow spirometers eliminate the risk (low) ofcross-contamination. 27 Flow Measuring Spirometer Disadvantages No real-time or hard copy tracings Reliance on electronic equipment FEV1.0 cannot be calculated by hand unless the time is indicated in seconds on a flow-volume tracing Some flow spirometers are more difficult to calibrate and may lose their calibration over time if not well maintained. 28 Equipment Maintenance Most spirometers need regular calibration to check accuracy Calibration is normally performed with a 3 litre syringe Some electronic spirometers do not require daily/weekly calibration Good equipment cleanliness and anti-infection control are important; check instruction manual Spirometers should be regularly serviced; check manufacturer’s recommendations 29 Technical Specifications MEASUREMENT DEVICE o Volume range, Accuracy o Flow range, Accuracy o Calibration method DISPLAYS PLOTS: Timed spirogram, Flow-volume loop DATA ANALYSIS HARD-COPYREPORT COMPUTER INTERFACE STERILIZING METHOD DISPOSABLE PARTS POWER REQUIREMENTS, STD List 30