Staffing RODS in Ohio February 23rd, 2006 Biosurveillance Information Exchange Working Group Rutgers University Piscataway, NJ Loren Shaffer, MPH Loren.Shaffer@odh.ohio.gov Early Event Surveillance Supervisor Our Current Systems • Real-time Outbreak and Disease Surveillance (RODS) System • BioSense • Influenza-like Illness Sentinel Providers • School Absenteeism • Wildlife Disease Surveillance • Ohio Disease Reporting System • Early Aberration Reporting System (EARS) RODS • Developed at the University of Pittsburgh • Utilizes a hospital’s existing HL-7 socket to receive realtime data • Interprets free-text chief complaint from emergency department registration database and groups into one of seven prodromes • Collects information from retailers about sales of over-thecounter medications • Provides immediate analysis for trends and anomalies suggestive of disease outbreaks • Secure web access by users HIPAA • Export of data for public health surveillance is permitted (45 CFR 164.512) • Prior written authorization of individual is not required (45 CFR 164.512) End Users of RODS in Ohio • Total = 174 – State Health Department = 6 – Local Health Department = 87 • 88 of 135 LHDs represented – Hospital = 77 – Other = 4 RODS Alerts • February 2004 to February 2006 – 310 unique alerts received • • • • Seasonal Elevation – 40% Outbreaks – 22% Data Errors – 9% No Cause Identified – 28% – 53% handled at State level – 47% forwarded to local epidemiologist RODS Alerts and Reported Outbreaks in Ohio 2/1/2004 - 2/1/2006 Date of RODS Alert 12/24/2004 Syndrome County Outbreak Cause Number Ill Respiratory Statewide CO Poisoning 1/11/2005 Gastrointestinal Franklin Norovirus 7 1/24/2005 1/11/2005 Gastrointestinal Franklin Norovirus 3 2/16/2005 1/30/2005 Gastrointestinal Mahoning Norovirus 5 2/9/2005 3/3/2005 Gastrointestinal Mahoning C perfringens 4 3/14/2005 10/26/2005 Gastrointestinal Preble Norovirus ~300 11/4/2005 11/23/2005 Rash Jefferson Scabies 5 not reported 12/27/2005 Gastrointestinal Montgomery Campylobacter 3 1/30/2006 8/3/2005 8/4/2005 8/5/2005 Gastrointestinal Constitutional Gastrointestinal Hamilton Cryptosporidiosis ~750 8/22/2005 1/9/2006 Constitutional Scioto Scromboid Poisoning 3 1/30/2006 Respiratory Erie Influenza-like Illness 24 not reported 1/18/2006 *Information about the number ill and date reported was obtained from the Ohio Disease Reporting System (ODRS) ~50 Date Reported to ODH not reported What are we doing with RODS? • Monitoring for patterns suggestive of an infectious disease outbreak • Influenza surveillance study & efforts • Retrospective outbreak study (improved specificity) • Adaptation to animal-based sources for emerging infectious disease surveillance • Real-time clinical data analysis • Environmental surveillance • Specialized investigations Influenza Influenza Summary of Correlation Analysis 2003/2004 and 2004/2005 Influenza Seasons Data Thermometer Cough & Cold Pediatric Cough Syrup Adult Cough Syrup Pediatric Cold Relief Adult Cold Relief Pediatric Antifever Adult Antifever VA Clinic Visits DoD Clinic Visits Class B Respiratory ED Visits Constitutional ED Visits ILI Sentinel Providers Franklin Montgomery Summit Average Lead Correlation Lead Correlation Lead Correlation Lead Correlation (weeks) Coefficient (weeks) Coefficient (weeks) Coefficient (weeks) Coefficient 4 0.5908 4 0.6254 3 0.5226 3.67 0.5796 4 0.5592 5 0.5728 3 0.4522 4.00 0.5281 4 0.5079 4 0.5487 3 0.4591 3.67 0.5052 4 0.2133 4 0.2938 3 0.3042 3.67 0.2704 4 0.5730 4 0.5236 4 0.4541 4.00 0.5169 4 0.5985 4 0.5875 4 0.4783 4.00 0.5548 5 0.5524 5 0.4626 3 0.3788 4.33 0.4646 5 0.3224 1 0.3844 5 0.1901 3.67 0.2990 7 0.3081 7 0.3159 -1 0.4470 4 0.5107 0 0.2594 1.00 0.4057 4 0.5544 5* 0.5227 4.00 0.5386 4 0.5133 4* 0.4603 4.00 0.4868 4.33 0.4536 5 0.2311 5 0.5591 3 0.5705 (4 w /o (0.5648 w /o School Absences Laboratory Analysis * = Data From 1 Influenza Season 10 0.2852 4* 5 0.4540 0.5943 5 3 0.3965 0.5966 Franklin) Franklin) 7.50 4.00 0.3786 0.5955 Known Outbreak ED Registrations P(↑Consitutional|Outbreak N)= xc P(↑Botulinic|Outbreak N)= xb P(↑Respiratory|Outbreak N)= xr P(↑GI|Outbreak N) = xg P(↑Hemorrhagic|Outbreak N)= xh P(↑Neurologic|Outbreak N)= xn P(↑Rash|Outbreak N)= xra OTC Sales P(↑Thermometer|Outbreak N)= xt P(↑Cold Relief|Outbreak N)= xcr P(↑Lozenges|Outbreak N)= xl P(↑Chest Rubs|Outbreak N) = xchr P(↑Bronchial Remedies|Outbreak N)= xbr P(↑Antifever|Outbreak N)= xa P(↑Other Categories|Outbreak N)= x Zoonotic Disease Surveillance • Adapt RODS to … – Veterinary Diagnostics Laboratory • Lab orders batched & transmitted via ftp • Parsed into syndrome categories based on previous mapping of tests • Spatial/temporal analysis at the ZIP code-level – Veterinary Clinic • Reason for Visit field included • Near real-time export via ftp • Co-co classifier parses free text into syndrome category • Spatial/temporal analysis at the ZIP code-level Areas for Attention & Assistance Continuous Continuous Emergency Department Chief Complaint and Patient Demographics In HL7 messages Categorize Into Syndromes Daily Daily Totals Totals Higher Than Expected? Review Trends Historical Models Alert Updated monthly Valid Alert? Initiate Response Identified Needs • • • • User Training → 1:1 & Conference Workshops User Protocols → Developed Protocol Document User Support → 24/7 Coverage Pilot 24/7 Coverage → System Enhancement to Permit Alerts to Jurisdictions • Advisory Group(s) → Expansion of ODRS Advisory Committee • Integration with Other Surveillance Systems → Ongoing Evaluations and Study Projects • Local Health Department Resources → ? Questions? Loren Shaffer Loren.Shaffer@odh.ohio.gov 614-728-3343