PSY 620P Messinger Design Developmental Designs Internal and External Validity of a Study Measurement Reliability and Validity of Measures Instrument Construction Stages Dealing with missing data Ethics in Developmental Studies Children as vulnerable population Assent Analysis Visualizing your data Hypothesis Testing Approaches to Analyzing Change over Time Replicability Access to samples Replicable (objective?) measurement Addressing the crisis… Strange Situation examples Ubisense examples What about SEM? What is causality? Mattson, et al.,PLOS One, 2013 Between subject A treatment (independent variable) is assigned randomly creating treatment and control groups Within-subject All infants get treatment and control Examples ▪ Rating study, Face-to-face still-face Estimated Marginal Means Estimated Marginal Means of MEASURE_1 .16 .14 .12 .10 .08 .06 EXP2 .04 Comparison .02 Exposed 1 SMILES Messinger 2 3 Quasi-experimental differences in naturally occurring groups Observational Differences in naturally occurring conditions Complementary, not exclusive Is age (development) studied experimentally or observationally? Messinger T indicates children who have just transition from junior high school Alfieri et al., 1996 Belfort et al., 2013 Quasi-experiment Between subject exploration of differences in naturally occurring groups Observational Differences in naturally occurring conditions ▪ Gazing at mother versus gazing away Messinger 0.8 Proportion of Open Mouth Smiling Only ▪ Drug exposure, breast-feeding, and attachment groups Figure 2b. Solo Open Mouth Smiling by Gazing at Mother 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0.0 Experimental and all observational approaches measures variables Variable - a measurable component of behavior or physiological functioning that can take on different values Not all aspects of behavior or physiology specific features of interest Messinger Intensive description in regular language Not measuring variables ▪ E.g., baby biography, one infant described over time Pro: Insight into individual and developmental process Emerged with romantic emphasis on individual Con: Not generalizable Complementary (counting themes), not exclusive, NIH Messinger Longitudinal vs. cross-sectional designs Same infants over time Pro: Answers ‘How do individuals change in time?’ Con: Takes a long time Typical Trajectory: Cognitive Scores Decline 110 Bayley Cognitive Score Attrition 120 100 90 80 70 60 50 1 Year M = 93.5 n = 200 Messinger 2 Years M = 79.1 n = 190 3 Years M = 82.1 n = 132 Rosenquist et al. PNAS | January 13, 2015 | vol. 112 | no. 2 | 357 Different infants at different times Pro: Efficient, large numbers of subjects Con: Differences do not necessarily reflect individual’s development e.g. cohort Messinger 95 90 85 80 75 70 65 60 55 50 One Year Two Year Three Year Different Individuals Development is relatively stable on large time scales Motor, physical, emotional, communicative But choppy on smaller scales Only longitudinal research can show individual development Messinger Messinger 6 mos.. 17” Birth 13.75” 12 mos. 18” Messinger 24 mos. 19” Developmental trajectories take many forms Accurate depiction of trajectory depends on sampling rate of observations Overly large sampling intervals can distort shape of change Inaccurate picture of developmental trajectory “Microgenetic method” – small time intervals to observe developmental process Jutagir How small is small enough? How large is too large? Previously, measurement intervals chosen by: Intuition, convenience, and tradition Jutagir Call for study design based on formal theoretical models about the shape of the underlying function Dictates number of data points and optimal spacing Difficult to apply in psychology “Chicken and egg” conundrum: Cannot mathematically calculate the shape of the function until we know the shape of the trajectory Jutagir Hoffman Study collected daily measurements of motor development Next, systematically manipulated data to alter time between assessments Observed how trajectories were affected Jutagir Results Many kids are variable in achieving motor skills Increased duration of time (as small as 2-3 days more) between assessment periods masks that variability Jutagir Continuity(=absolute change) Behavior level is continuous (discontinuous) across ages How does a behavior change in form and/or function over the course of development? Stability Rank of individual in group is stable Typical Trajectory: Cognitive Scores Decline How does a behavior change differently among individuals in the same group? (=relative change) 120 110 Bayley Cognitive Score 100 90 80 70 60 50 1 Messinger Year M = 93.5 n = 200 2 Years M = 79.1 n = 190 3 Years M = 82.1 n = 132 Validity of Developmental Studies External validity = Internal validity = Methodological soundness of study allowing changes in DV to be attributed to the IV Threats to internal validity = uncontrolled confounds ▪ Need to control for various methodological confounds through adequate sampling, random assignment (when possible), inclusion of control group etc. Threats of particular concern in Developmental Studies (cont) History: Maturation: Testing: Instrumentation: Regression: ▪ Example of Regression * Selection effect Threats of particular concern in Developmental Studies: Regression High anxious freshmen selected for intervention in first week of school; by midyear show significant decrease in anxiety Pretest 90 Intervention Posttest 70 The process of quantifying abstract concepts such as: ▪ Intelligence ▪ Sociability ▪ Emotion Regulation Developmental assessments often rely on indirect measures i.e., habituation as processing index Are we measuring what we think we’re measuring, Do the variables measured the constructs mentioned in the research questions? There is no final answer ▪ ▪ ▪ ▪ Reunion behavior = Attachment? Smiling = Joy? Looking = Preference? Heart rate = Arousal? Messinger Requires Detailed operational definitions Creation of sensitive instruments Rules for scoring instrument to create summary scores Validity Does measure provide intended information for intended population? ▪ Can vary with age and subgroup (e.g., ethnicity or SES) Reliability How consistent is children’s behavior? ▪ Tends to increases with age and diversity of sample Observed on-line or video-recorded Measured with Trait rating - global judgement Time sampling Event sampling (frequency) Event sampling (duration) Messinger Messinger Heart rate & respiration (video) avoidant infants, infants on visual cliff Electroencephalogram Relative lateral activation during crying Actigraphy Index of ADD? Increasingly important supplement to behavioral measures Messinger Missing Data Most common reason for low power in studies of change over time Options Deletion Substitution Imputation The methodological literature favors maximum likelihood and multiple imputation a strong theoretical foundation, less restrictive assumptions, and the potential for bias reduction and greater power. Benefits are especially important for developmental research where attrition is a pervasive problem Enders, Craig K. Child Development Perspectives, Vol 7(1), Mar 2013, 27-31. Reliability Consistency of measurement ▪ Inter-rater reliability of observations Bias Systematic impact of unmeasured variables ▪ Blinding in drug studies ▪ Keeping observations independent Messinger Analysis Approaches to Analyzing Change over Time ▪ Describing group level patterns of change over time ▪ Describing individual differences in patterns of change ▪ Processes underlying/modifying patterns of change ▪ Mediating and moderating variables