BIOL 1406 CRN 76433 – GENERAL BIOLOGY I (Spring 2012) INSTRUCTOR: Mr. Michael Sanregret (email: michael.sanregret@hccs.edu) COURSE DESCRIPTION: Discussions focus on biological chemistry, biological processes, cellular morphology, metabolism, genetics and molecular biology. This is a Core Curriculum course and cannot be used in conjunction with 1308. Students will construct an understanding of biological concepts by participating in lab activities, online and in-class discussion activities. Student comprehension of biological concepts will be assessed by Mastering Biology homework assignments and lecture and lab exams. STUDENT LEARNING OBJECTIVES: 1. Explain synthesis of polymers, and the properties of the classes of biomolecules. 2. Demonstrate knowledge of shape, structure, and function of all eukaryotic cellular organelles and cell systems. 3. Demonstrate knowledge of base pairing rules for both DNA and RNA. 4. Demonstrate understanding of replication and transcription and translation. 5. Be able to properly use and focus microscope to find specimen on slide. 6. Understand principles of heredity in terms of chromosomal inheritance. TEXT BOOKS: Lecture: Biology, Campbell, Neil, Reece, Jane 9th edition, Pierson Benjamin Cummings, 2011. The portion of this book used for BIOL 1406 is sold separately as Volume I though the HCC bookstore. The Campbell text comes with access to the website Mastering Biology. Use of this website is a required activity and will included graded homeworks. Lab: General Biology I Lab Manual: A Hands-on Experience, 2nd ed. Wagle, Turell (ed) Royal Publishing Co. 2010 EAGLE ONLINE: All of the important documents for the course and other study aids will be made available on Eagle Online: https://hccs1.mrooms3.net/login/index.php Try to check Eagle Online daily, since there may be important announcements about the course. TIME AND LOCATION: Lecture: Tuesday 5:30-8:30 in LHSB 304 Lab: Thursday 5:30-8:30 in LHSB 305 GRADING: Grades will be determined by the following items: Four lecture exams (100 points each) Lab exit check (10 pts per lab) Lab clean up (2 pts per lab) Mastering Biology website homework (variable points each) Eagle Online discussion participation (10 points each) Attendance (2 points per each lecture and lab period) One cumulative final exam (100 points) Your lowest lecture exam grade will be dropped. The cumulative final exam grade will never be dropped as a low grade, although you may gain an exemption from the final exam. Your final percent grade will be calculated as your total points divided by the total possible times 100%. Your final letter grade will be determined by your final percent grade as follows: 90-100% = A 80-89% = B 70-79% = C 60-69% = D <60% = F EXAMS: Lecture exams will test your knowledge and understanding of concepts learned in lecture or in class activities during lecture. Lab topics will not be specifically covered, although there will of course be overlap in the material. The format will be multiple choice, completion, matching, diagrams, definitions and essays. On the day of a lecture exam, you will be given a one hour period to complete the exam. After a break, we will start the next section of lecture material (attendance following the exam is required). The first three lecture exams will be given on scheduled class days. The fourth lecture exam will be given during the final exam period during finals week. You get to drop the one lowest grade out of the four 100 point exams given during the semester. In general, I do not give make up exams. During the final exam period on May 8th, you will be given two exams: the fourth lecture exam and a cumulative departmental final (i.e. not written by Mr. Sanregret). The departmental final will count for 100 points and cannot be counted as your drop grade. After exams are graded they will be returned and we will review the answers. After the review, you must return your exam question sheet to me (you may keep the scantron answer sheet). If you wish to see an exam question sheet at a later point ask me I will make it available to you. If you miss one, it counts as your dropped grade. If you miss a second exam for a serious reason, accommodations may be made. LAB EXIT CHECK: Participation in the lab will be assessed by an “exit check.” You will have to perform some skills learned in lab to answer questions to get credit for the exit check. If you fail to complete the exit check, you can return again to try to do better. The exit check is worth 10 points per lab. MASTERING BIOLOGY HOMEWORK: You will be given a number of Mastering Biology homework assignments during the semester, at times to be announced. These assignments must be completed online at http://www.masteringbiology.com. You are required to buy the Campbell Biology textbook and and the code that allows you to log in to the website. These assignments are based on chapters of the textbook and will complement what is covered in class. The assignments will cover recently studied in class, and should help you to comprehend the material. The procedures for logging in to the website will be discussed in class. To enroll in this course in Mastering Biology, you will need the Mastering Biology name of this course. It is SP2012SANREGRET76433 The availability and dues dates for Mastering Biology assignments will be posted on Eagle Online. The first assignment is an orientation to Mastering Biology. It is available now and is due January 24 th at 11PM. EAGLE ONLINE PARTICIPATION: There will be approximately four topics for you to discuss in forums on Eagle Online. The topics will be announced in class. More on this will be explained later. ATTENDANCE and WITHDRAWALS: As noted in the grading section, you will be graded on attendance. Make note, however, that I do not automatically drop students from the roster for lack of attendance. If you intend to drop the class, you should ask me to submit a withdrawal online before the last day for student withdrawals (March 29th, 4:30PM). This is the only way to receive a “W” grade at the end of the semester. If you do not arrange for withdrawal by March 29th, 4:30PM, you will receive a regular letter grade at the end of the semester (F, D, C, B, or A, depending on grade average). Just to be clear, I do not have the power to give a W grade after March 29th. Texas law currently limits the total number of course withdrawals a new student may take in their entire educational career to no more than six. Also be aware that the current policy in Texas public colleges and universities requires students who repeat a course for a third time or more will be charged an additional $50/credit hour. There has been a recent change in the grading system for students who receive an F in a course. Students who fail due to lack of attendance may be given the grade “FX,” which indicates the lack of attendance. An FX grade may have an effect on the student’s eligibility for financial aid. ASSISTANCE: If you have questions about the course material, I encourage you to ask me questions during or outside of class, or over email (michael.sanregret@hccs.edu). We may also schedule a time to meet to discuss course material. Tutoring is available (times and locations TBA). The most reliable way to contact me is over email. If you make a request during class for some later action, I will probably forget, so send me an email to remind me. Exchange phone numbers with some of your classmates because you may want to form study groups or you may need to find out about missed classes. The Biology/Nutrition Dept. has developed lab study pages that are helpful when reviewing your lab material. The URL is: http://cc.hccs.edu/Biology/AllStudyPages/StudyPagesSummary/1406.htm APPEALING GRADES: If you believe that your work has been graded incorrectly, you must contact me within a week (not counting holidays) after the grade is given to discuss the grade. Exceptions may be made for illness or other valid excuses. Difficulties that cannot be resolved through me should be brought to the Biology Associate Chair, Pramila Sen in LHSB 401. RULES AND REGULATIONS 1. LAST day to register/add/drop/swap: . 2. Textbook and lab manual are required. 3. Full Class attendance is required. Students are responsible for everything covered during their absence, and it is the student’s responsibility to consult with the instructor for make-up assignments. 4. To avoid disruption in the classroom, all pagers must be set on the silent mode. Cellular phones must also be turned off during the class period. 5. No children are allowed in the laboratory. 6. Eating, drinking, or smoking is NOT allowed in the laboratory. 7. You must read the laboratory safety rules before doing any of the lab exercises. 8. The laboratory safety release form must be signed during the first lab session. 9. Lab reports are an important part of the course and to be completed one week after the lab period. They will be spot-checked during the lab period. Although students work in groups, individual active participation is expected. You are responsible for the completion of your individual lab report. 10. CHEATING IS NOT PERMITTED!!! If it occurs the student may receive a zero for the exam or a grade of “F” in the course. 11. Grades will not be posted at any time during the semester. Your grade will be available on the web (www.getgrades.com) or by telephone (1-877-341-4300) 12. Students who require reasonable accommodations for disabilities are encouraged to report to Room LHSB 106, or call (713) 718-6164 to make necessary arrangements. Faculty are only authorized to provide accommodations requested by the Disability Support Services Office 16. Open labs will be scheduled during the semester for review of lab materials. The schedule will be available in your classroom during the semester 17. The Biology Computer lab is in Room LHSB 415, computers and biology software are available for student use. Biology tutoring will also be available in the lab. The scheduled will be posted in the classroom. TENTATIVE SCHEDULE: Chapter Lecture (Tuesday) Lab (Thursday) 4: 2/7-2/9 1 2 3 4 5 6 7 Introduction The Chemical Context of Life Water and the Fitness of the Environment Carbon and Molecular Diversity of Life Macromolecules Cell First exam; Membrane Structure and Function 5: 2/14-2/16 8 An Introduction to Metabolism Orientation 1. Measurements 2. Basic Chemistry 3. Water and its Properties 4. Biomolecules: Carbs/Prot. 5. Biomolecules: Lipids/Nucl. 6. The Compound Microscope 7. Cell Structure and Function 8. Diffusion and Osmosis 6: 2/21-2/23 7: 2/28-3/2 9 10 Cellular Respiration Photosynthesis 9. Enzymes: Catalysts of Life 10. Cellular Respiration 8: 3/6-3/8 9: 3/20-3/22 11 12 13 Second exam; Cell Communication Cell Cycle Meiosis 11. Photosynthesis 12. Mitosis 10: 3/27-3/29 11: 4/3-4/5 14 15 16 17 18 19 20 21 Mendelian genetics Chromosomal Inheritance DNA structure Third exam; Protein Synthesis Genetics of Viruses and Bacteria Eukaryotic Genomes DNA Technology and Genomics Genome Evolution Review, time to catch up on lecture material 13. 14. 15. 16. Final exam (5:30-7:30PM): Fourth lecture exam and departmental final Extra credit projects Week 1: 1/17-1/19 2: 1/24-1/26 3: 1/31-2/2 12: 4/10-4/12 13: 4/17-4/19 14: 4/24-4/26 15: 5/1-5/3 16: 5/8 Meiosis Karyotyping and Barr body staining Genetics: Mendelian Non-Mendelian genetics and human heredity 17. DNA extraction, structure and replication 18. Protein synthesis 19. Gel electrophoresis