Course Syllabus
Adv. Positron Emission Tomography (PET) & Fusion Tech.
NMTT 2333
Semester with
Course Reference
Number (CRN)
SUMMER 2012
CRN 87599
Instructor contact L. Rene Hyder;
information (phone Phone: 713-718-7355;
number and email Email: rene.hyder@hccs.edu
address)
Office Location
and Hours
Coleman College for Health Sciences
Room 524
Hours: Mon. 8-11 am; Tue. 8:00-9:00 am; Fri. 8:00-9:00
Course
Location/Times
Monday 1:00 – 4:20 and Friday 1:00-4:00 in room 574
Course Semester
Credit Hours (SCH)
(lecture, lab) If
applicable
Credit Hours
3.00
Lecture Hours
3.00
Laboratory Hours
External Hours
Total Course
Contact Hours
48.00
Continuing
Education Units
(CEU): if
applicable
Course Length
(number of weeks)
8 weeks
Type of Instruction Lecture
Web-enhanced
Course
Description:
Advance study in the field of positron emission tomography and fusion technology.
1
Course
Prerequisite(s)
PREREQUISITE(S):

NMTT 1409
FREQUENT REQUISITES
 College Level Writing
 Departmental approval
 Admission to the Program
 College Level Reading
 College Level Mathematics
Academic
Discipline/CTE
Program Learning
Outcomes
1. Prepare and administer radiopharmaceuticals.
2. Correlate nuclear medicine procedures with normal anatomy/physiology and abnormal
pathology.
3. Utilize proper methods of patient care.
4. Demonstrate radiation safety techniques to minimize radiation exposure.
5. Perform quality control procedures.
6. Competently perform imaging and non-imaging nuclear medicine procedures.
Course Student
Learning
Outcomes (SLO): 4
to 7
1. Explain the methodology of positron emission tomography and fusion technology.
2. Describe radiopharmaceuticals used and their patterns of biodistribution.
3. Identify required instrumentation and quality control measures.
4. Outline associated patient preparation."
5. Detail the usage of PACS, teleradiology, and other systems used in the healthcare setting
to manage, store and transmit information.
Learning
Objectives
(Numbering
system should be
linked to SLO e.g., 1.1, 1.2, 1.3,
etc.)
Explain the methodology of positron emission tomography and fusion technology.
1. Discuss how a PET, PET/CT, and/or SPECT/CT scan for oncology, cardiac and/or brain
imaging is acquired.
Describe radiopharmaceuticals used and their patterns of biodistribution.
1. Identify the radiopharmaceuticals used for PET, PET/CT and/or SPECT/CT.
2. Discuss the biodistribution of the radiopharmaceuticals used in PET, PET/CT
and SPECT/CT imaging.
Identify required instrumentation and quality control measures.
1. Detail the components of a PET, PET/CT and SPECT/CT imagers.
2. Discuss the quality control studies performed on PET, PET/CT and SPECT/CT imagers.
Outline associated patient preparation."
1. List the patient preparation steps utilized in PET, PET/CT and SPECT/CT imaging.
2. Compare the images acquired when the patient is properly prepared for a study versus not
correctly prepared for a study.
Detail the usage of PACS, teleradiology, and other systems used in the healthcare
setting to manage, store and transmit information.
1. Explain how acquired patient data is viewed, processed and archived on a PACS system.
2. Discuss the utilization of radiology and hospital information systems used to manage
patient information in accordance with facility policies, state and federal statues and
accreditation standards.
SCANS and/or
Core Curriculum
Competencies: If
applicable
SCANS
Explain the methodology of positron emission tomography and fusion technology.
Foundation Skills - Basic -Writing
Describe radiopharmaceuticals used and their patterns of biodistribution.
Foundation Skills - Basic -Writing
Identify required instrumentation and quality control measures.
Foundation Skills - Basic -Writing
Outline associated patient preparation."
2
Foundation Skills - Basic -Writing
Detail the usage of PACS, teleradiology, and other systems used in the healthcare
setting to manage, store and transmit information.
NMTT - 2333 PET COURSE ; SUMMER 2012
Course Calendar
CLASS : Mondays 1:00-4:20 pm & Fridays 1:00 am - 4:00 pm for 8 weeks
TEXTBOOKS: Nuclear Medicine and PET/CT
Technology and Techniques,
Christian & Waterstram-Rich,
7TH Ed.,Mosby, 2012
WEEK
1
Mon., 5/14
Nuclear Medicine Procedure Manual
Klingensmith, Eshima, Goodard
Wick, 2012-2014
CONTENT
ASSIGNMENT
Radiopharmaceuticals: Production & Characteristics
Objectives:
Christian:
152-156,
Ms.
Hyder
1. Identify the radiopharmaceutical used in PET imaging
and their methods of production
168-173,
2. Identify the clinical uses of PET and PET/CT
319-327
3. Define “occult” lesions as indicated in this lecture
PM: 92
4. Describe the components and operation of a cyclotron
5. List the advantages of PET radiopharmaceuticals
6. Describe the physics of positrons decay and emissions
7. List detector crystals that can be used for PET imaging
and describe their properties
8. Explain the fundamental operation of dedicated PET
scanners and their design
9. Discuss 2D and 3D imaging and the advantages and
disadvantages of each
10. Describe the detection of true, scatter and random events
11. Describe transmission images and it's use in attenuation
correction of PET images
12. Discuss attenuation correction techniques in PET
13.. Discuss the design of a PET/CT scanner
14. Discuss the advantages of a PET/CT Scanner
15. Explain how the CT transmission scan is utilized
3
WEEK
1
Fri., 5/18
CONTENT
ASSIGNMENT
CT Physics & Instrumentation
Objectives:
Christian:
Chapter 11
** 12-3 **
Roger
Bumgardner
MPh,
RT: (R),(N),
& (CT
1. Describe the physics processes involved in the
production of x-rays
2. Describe the role of each component in the x-ray tube
and its operation
3. Discuss the proper adjustment of the x-ray tube voltage
and current in CT
4. Name the principle parts of a CT scanner and the
function of each component
5. Describe how helical CT scanner operates and the
component changes made this technology possible
6. Discuss how CT image data are acquired and processed
7. Describe the calculation process of Hounsfield units
8. Describe CT number values assigned to various tissues
and how these values are assigned into meaningful
display windowing
9. List parameters set by the operator for CT use and
describe the effect of each on the images
10. Discuss CT Image quality issues
12. Describe the parameters and imaging characteristics
required for a diagnostic quality CT scan
13. Discuss patient & occupational radiation exposure from
a CT scanner
2
Mon.,5/21
PET Instrumentation Part 2
Objectives:
Christian:
327-342,
Jeff Evrard,
PETNET
1. Explain the pharmacokinetics of FDG
2. Describe the normal and abnormal distribution of F-18-FDG
3. Describe the patient preparation for a F-18-FDG oncology
study
4. Identify the usual adult and pediatric dosage and route of
administration
5. Explain patient positioning for the dosing and scanning for
F-18-FDG
6. List the indications for oncology imaging with F-18-FDG
7. Discuss the impact of FDAMA on the growth of PET
8. List the indications for cardiology imaging with PET
9. List the radiopharmaceuticals used for PET Cardiac
Imaging
10. Explain patient preparation for PET cardiac studies
11 . Explain how a Sr82/Rb-82 generator/infusion system is
used to dose patient
12. List the indications for brain imaging with PET/CT
13. List the advantages of using F-18-F-Na for bone PET
imaging
14. List two other current PET radiopharmaceuticals and their
proposed use
15. Describe the appearance of attenuation corrected versus
non corrected images
16. Describe the process of storing reconstructed data in
sinograms and reconstruction methods in PET
391-396
PM: 36,
37,
40
4
WEEK
2
Fri., 5/25
CONTENT
ASSIGNMENT
Radiation Safety
Objectives:
Christian:
Hyder
347-349,
1. Describe the radiation safety techniques used to reduce
radiation exposure in PET imaging
2. Discuss patient radiation exposure from PET and CT
scanner
3. Discuss occupational radiation exposure from operating
a CT scanner
4. List the HVL of lead for Tc-99m vs F-18 and the HVL of
tungsten for F-18
5. What are the items considered in getting a site ready for
F-18 studies
372-373,
189-199
PET/CT Scanners
1. Discuss the evolution of the PET/CT scanners
1. Discuss various manufacturers of PET/CT scanners
3
Mon., 5/28
3
Fri, 6/1
Memorial Day Holiday
PET, CT & PET/CT
Quality Assurance
Objectives:
1. Discuss a PET quality control program, including:
blank scan, absolute activity calibration, normalization
scan, sinogram, coincidence timing window, gain and
energy calibration, etc.
2. Describe a CT Quality control program
3. List the origin of CT and PET/CT image artifacts and how
they may be prevented
4. Explain truncation and its effect on image quality
5. Discuss the integration of CT procedures into the
combined PET/CT examination
6. Discuss the critical elements in generating quantitative
measurements
7. Discuss SUV
8. Discuss appropriate parameters for the acquisition of
low dose CT for PET attenuation correction
Christian:
342-345,,
373-374
PM: 16, 17
Review previously discussed information
5
WEEK
4
Mon., 6/ 4
CONTENT
ASSIGNMENT
SPECT/CT Instrumentation
Objectives:
Christian:
Chapter 9
Dr.
Kappadath
4
Fri., 6/ 8
1. Discuss the components of a SPECT camera
2. Describe the principles of tomographic reconstruction
3. Discuss the physics of SPECT relative to attenuation,
scatter, reconstruction and detector response
4. Describe the attenuation correction performed by
transmission imaging
5. Discuss advantages of SPECT/CT systems
6. Describe image quality and artifacts in SPECT/CT
imaging
7. Discuss scatter correction methods
8. Discuss gray scale versus color display
9. List quality control test performed specifically for SPECT
Patient Preparation & Artifacts
Objectives:
Christian:
391-398
MDACC
PET
Brandon
Simon
5
Mon., 6/ 11
5
Fri., 6/ 15
1:00-4:00
6
Mon., 6 / 18
1. Describe the patient preparation for oncology studies
2. Explain the patient preparation differences for
cardiology, brain and oncology studies
3. Describe the normal distribution of F-18-FDG
4. Discuss appropriate acquisition parameters for
PET and CT
5. Describe various artifacts that may be seen in PET images
6. Define SUV and explain how it is calculated and used;
Discuss how it can be effected by incorrect patient
Preparation
Review for Mid-Term Exam; Smith / Hyder
MID-TERM EXAM
Fusion Technology & Infomatics
Objectives:
** 9-12 **
Martha Mar
PM: 82
Christian:
347-348
1. Explain the DICOM system
2. Discuss computer programming and programming
languages
3. Explain digital storage of images
4. Diagram computer network configurations
5. Discuss uses of non-imaging computers
6. Discuss dedicated PET images & QC
6
WEEK
6
Fri., 6/ 22
Ms.
Hyder
7
Mon., 6/ 25
MDACC
Dr. Rohen
7
Fri., 6/ 29
9:00-12:00
CONTENT
PET Oncology 1: Clinical Indications for PET/CT
Objectives:
ASSIGNMENT
Christian;
402-418
1. Discuss the different types of PET oncology applications
2. Discuss the various scanning protocols for PET/CT and
when they are used with each type of cancer
3. Explain the steps in properly preparing a patient for a
PET/CT oncology study
4. Describe the patient positioning and comfort issues that
hinder the acquisition of a quality PET/CT study
5. Discuss the significance of peripheral blood glucose levels
in FDG imaging
6. Discuss the value of future PET oncology radiotracers
7. Discuss the potential future directions of PET/CT oncology
PET Oncology 2
Objectives:
1. Discuss benign causes of increased FDG uptake
2. Identify normal and abnormal PET/CT images
3. Identify patterns associated with the various types of
cancer using PET/CT
4. Identify artifacts in PET/CT oncology images
5. Discuss the normal pattern of head and neck FDG
Activity
PET/CT & SPECT/CT Brain Imaging
Objectives:
Christian:
436-441
Andrea
Vinson
Methodist
Hospital
1. List the radiopharmaceutical used in PET/CT brain
imaging and associated patient preparation
2. Describe the procedure used in PET/CT brain imaging
3. Identify normal and abnormal PET/CT images
4. Identify artifacts in PET/CT brain Images
5. Describe the advantages and disadvantages of PET
brain images compared to SPECT images
PET/CT & SPECT/CT Cardiology { Review }
Objectives:
1. List the radiopharmaceuticals used in PET cardiac
Imaging and how they are administered
2. Describe the various patterns of normal FDG myocardial
uptake
3. Describe the protocol for PET/CT cardiac imaging
4. Describe the technique used to acquire SPECT/CT
images
5. Identify normal and abnormal cardiac PET/CT &
SPECT/CT images
6. Identify artifacts in cardiac PET/CT & SPECT/CT images
7. Describe the technique used to acquire gated SPECT
cardiac results
PM: 42,
45
Christian:
520-523
PM: 36,
37,
40
7
WEEK
CONTENT
8
Mon., 7/2
1:30-3:30
REVIEW
8
Fri., 7/6
1:00-4:00
ASSIGNMENT
FINAL EXAM
Instructional
Methods
Web-enhanced (49% or less)
Face to Face
Student
Assignments
Explain the methodology of positron emission tomography and fusion technology.
Various assigned readings from textbooks, peer-rev
Papers
Describe radiopharmaceuticals used and their patterns of biodistribution.
Various assigned readings from textbooks, peer-rev
Papers
Identify required instrumentation and quality control measures.
Various assigned readings from textbooks, peer-rev
Papers
Outline associated patient preparation."
Papers
Various assigned readings from textbooks, peer-rev
Detail the usage of PACS, teleradiology, and other systems used in the healthcare
setting to manage, store and transmit information.
Various assigned readings from textbooks, peer-rev
Student
Assessment(s)
Explain the methodology of positron emission tomography and fusion technology.
Quizzes/Tests which may include: definitions, matching, multiple choice, true/false, short
answer, brief essay
Various assigned readings from textbooks
Writing papers including essays, analyses, reviews, research, comparing and contrasting
Research papers
Describe radiopharmaceuticals used and their patterns of biodistribution.
Quizzes/Tests which may include: definitions, matching, multiple choice, true/false, short
answer, brief essay
Various assigned readings from textbooks
Writing papers including essays, analyses, reviews, research, comparing and contrasting
Research papers
Identify required instrumentation and quality control measures.
Reading and then writing about seminal texts and theories
Quizzes/Tests which may include: definitions, matching, multiple choice, true/false, short
answer, brief essay
Various assigned readings from textbooks
Writing papers including essays, analyses, reviews, research, comparing and contrasting
Research papers
Outline associated patient preparation."
Reading and then writing about seminal texts and theories
Quizzes/Tests which may include: definitions, matching, multiple choice, true/false, short
answer, brief essay
Various assigned readings from textbooks
Writing papers including essays, analyses, reviews, research, comparing and contrasting
Research papers
Detail the usage of PACS, teleradiology, and other systems used in the healthcare
setting to manage, store and transmit information.
Quizzes/Tests which may include: definitions, matching, multiple choice, true/false, short
8
answer, brief essay
Various assigned readings from textbooks
Instructor's
Requirements
All students are expected to attend classes regularly in which they are enrolled. Attendance
will be checked regularly by the instructor. Any student may be dropped from a course after
accumulating absences in excess of 12.5 percent of the total hours of instruction, which is
6.25 hours for this course
If a student enters the class more than thirty minutes after class has begun or leaves
more than thirty minutes before the class ends, the student will be counted as absent
for the entire class time.
Program/Discipline Students absent at the time when a major exam or class quiz is given will have NO MAKE-UP
EXAMINATION. This also includes a student who comes to class late. Student will not be
Requirements: If
allowed to take exams at a later time during the class. All exams will have time periods
applicable
designated therefore all test papers and practicals must be terminated at the end of that time
period. This policy is absolutely necessary in order to carry out all laboratory activities in the
given time period and allow for fairness to all students present.
Any student absent from the classroom for a major scheduled exam will have the percent (%)
value of that exam added to the percent value of the appropriate FINAL EXAM. For example:
If the Mid-Term Exam was missed, the 43% value would be added to the Comprehensive
Final Exam and it would then be worth 88%.
All laboratory assignments are to be done outside the class, completed and turned in at the
beginning of the next class.
A student will lose 10 points on a lab assignment if the assignment is not turned in at the
beginning of the lab and will lose 10 additional points a day (not including weekends) until
the assignment is turned in. If the graded assignment has been returned.
Final examinations must be taken on the day and time designated by the instructor, unless
there is a personal illness, accident or death in the immediate family (parent, child, brother,
sister, spouse or grandparent). In the event any of these occur, the student must call and
speak personally with the instructor or department head on the day of the examination.
The student must provide documented evidence of the reason for missing the examination:
doctor's statement in the case of personal illness, an accident report in the case of an accident,
or obituary or funeral program in the case of death in the immediate family. This
documentation must be provided prior to taking a make-up final examination.
The make-up final must be taken within 7 working days from the original test date or at the
discretion of the instructor. In the case of a severe injury or long term illness, the student will
be given an "I", incomplete, until the final examination is taken. An "I" will automatically turn
into an "F" if the student does not take the examination by the end of the following term
(excluding Summer). A student may not register for the next semester's nuclear medicine
technology courses, if they have an incomplete in any of their nuclear medicine technology
courses.
If notification on the day of a missed final examination to the involved instructor/department
head by the student is not made, a student will receive a 0 for their final exam grade and
course's final grade will be calculated as prescribed in the individual course syllabi. Also,
if documented evidence as described in the preceding paragraph is not provided, a student
will receive a 0 on their final examination.
For other program/discipline requirements: see Nuclear Medicine Technology Program
Student Handbook.
HCC Grading
Scale
A = 100- 90
B = 89 - 80:
C = 79 - 70:
4 points per semester hour
3 points per semester hour
2 points per semester hour
9
D = 69 - 60
1 point per semester hour
59 and below = F
0 points per semester hour
IP (In Progress)
0 points per semester hour
W(Withdrawn)
0 points per semester hour
I (Incomplete)
0 points per semester hour
AUD (Audit)
0 points per semester hour
IP (In Progress) is given only in certain developmental courses. The student must re-enroll
to receive credit. COM (Completed) is given in non-credit and continuing education courses.
To compute grade point average (GPA), divide the total grade points by the total number of
semester hours attempted. The grades "IP," "COM" and "I" do not affect GPA.
For Health Science programs, see the Program/Discipline Requirements section for specific
grading requirements.
Instructor Grading
Criteria
METHOD FOR DETERMINING COURSE GRADE
Assignments/Class work/Quizzes
12%
Mid-Term Exams
43%
Final Examination
45%
NUCLEAR MEDICINE TECHNOLOGY PROGRAM GRADING SCALE
90 - 100
A
80 - 89
B
75 - 79
C
Below 75
Instructional
Materials
F
Remember: You need a C or better to continue
to the next semester
Nuclear Medicine Procedure Manual, Klingensmith, Eshima, Goddard,
Wick Publishing, 2009-2011
Nuclear Medicine and PET/CT, Christian & Waterstram-Rich, Mosby, 2007
HCC Policy Statement:
Access Student
Services Policies
on their Web site:
http://hccs.edu/student-rights
Distance Education and/or Continuing Education Policies
Access DE
Policies on their
Web site:
http://de.hccs.edu/Distance_Ed/DE_Home/faculty_resources/PDFs/DE_Syllabus.pdf
Access CE
Policies on their
Web site:
http://hccs.edu/CE-student-guidelines
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