2014-2015 Calendar Proof CHEM CHEMISTRY Students should note that in the Science Faculty the minimum acceptable grade in a course which is required by a particular program or is used to meet a prerequisite, is a "C". Any student who fails to attain a "C" or better in such a course must repeat the course (at the next regular session) until a grade of "C" or better is attained. Students will not be eligible for graduation until such deficiencies are removed. The only exception may be granted for a single course with a “D” grade that is a normal part of the final year of that program, and is being taken for the first time in the final year. Valid WHMIS (Workplace Hazardous Materials Information System) certification is required for all students who wish to take CHEM laboratory courses. WHMIS certification workshops will be provided. Information regarding WHMIS training will be provided during the first week of classes. Note: See Courses -> Saint John or Fredericton -> Standard Course Abbreviations in the online undergraduate calendar for an explanation of abbreviations, course numbers and coding. CHEM 1001 General Chemistry I 3 ch (3C 1T) An introduction to atoms and molecules, chemical equations and reactions, the periodic table, the electronic structure of atoms, and chemical bonding as well as an introduction to organic chemistry including structure and bonding, functional groups, isomers, reactions and polymers. An adequate high school background in math and chemistry is required. CHEM 1006 General Chemistry Laboratory I 2 ch (3L) Topics include: measurements and statistics, inorganic and organic synthesis, qualitative and quantitative analysis, and molecular geometry. WHMIS certification required (see beginning of Chemistry Courses section for details). Co-requisite: CHEM 1001. CHEM 1012 General Chemistry II 3 ch (3C 1T) An introduction to gases, thermochemistry, rates of reaction, chemical equilibrium, spontaneity of reactions, reactions in aqueous solution, acids and bases, acid-base equilibria, solubility equilibria, redox reactions, and electrochemistry. Note: Credit can be obtained for only one of CHEM 1012 or CHEM 1982. Prerequisite: CHEM 1001; Corequisite: MATH 1003 or equivalent. CHEM 1017 General Chemistry Laboratory II 2 ch (3L) Topics include: ideal gases, heats and rates of reactions, chemical equilibria, acid-base equilibria, redox titrations, and voltaic cells. WHMIS certification required (see beginning of Chemistry Courses section for details). Note: Credit can be obtained for 1|Page 2014-2015 Calendar Proof only one of CHEM 1017 or CHEM 1987. Prerequisite: CHEM 1006; Co-requisite: CHEM 1012. CHEM 1553 Hitchhiker’s Guide to Chemistry 3 ch (3C) This course is intended for Arts or other students not in Science and Engineering and who have little or no chemistry background. The course will cover the basic principles and concepts of atoms and molecules, chemical bonding, acids and bases, and organic compounds. The material will be applied to the understanding of “everyday” chemistry including proteins, carbohydrates, polymers, acid rain, etc. This course cannot be used as a substitute for any other first level Chemistry course. CHEM 1982 General Applied Chemistry 3 ch (3C 1T) Intended primarily for non-science majors. Building on examples from environmental chemistry, polymers, fuel cells and corrosion, this course covers chemical material properties, solutions & solubility, kinetics & equilibrium, acids & bases, thermodynamics and electrochemistry. Note: Credit can be obtained for only one of CHEM 1012 or CHEM 1982. Prerequisite: 70% in Grade 12 Chemistry. CHEM 1987 General Applied Chemistry Laboratory 2 ch (3L) Intended primarily for non-science majors students. Topics include: ideal gases, heats and rates of reactions, chemical equilibria, acid-base equilibria, redox titrations, and voltaic cells. WHMIS certification required (see beginning of Chemistry Courses section for details). Note: Credit can be obtained for only one of CHEM 1017 or CHEM 1987. Prerequisite: 70% in Grade 12 Chemistry. Co-requisite: CHEM 1982. CHEM 2002 Quantum Chemistry I 4 ch (3C 1L) Molecular symmetry. Basic quantum theory and solutions for simple models. The orbital (Hartree-Fock) model for molecules. The Huckel model. Selected contemporary topics. Includes a computer laboratory component. Prerequisite: CHEM 1001, MATH 2003. Corequisite MATH 2213 or equivalent. CHEM 2009 Experience in Chemistry Research I 3 ch (3L) [W] CHEM 2009 is a project based course where students conduct research under the supervision of a chosen faculty member. Students must have declared a Science Major and must have a CGPA of 3.7 or better to enter after first year or a CGPA of 3.0 or higher to enter after second year. Students will be provided with a list of projects and applicant’s names will be forwarded to project supervisors. Applications must be made to the Director of Undergraduate Studies by May 15. Project assignment will be made by the Director of Undergraduate Studies and enrolment may be limited. Students are encouraged to plan for alternative courses in the case that no suitable project is available. A minimum of at least 3 scheduled hours per week is required and one seminar presentation will be required at the end of the academic year, as well as a written report. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 1001, 1006, 1012, and 1017. 2|Page 2014-2015 Calendar Proof CHEM 2111 Analytical Chemistry I 5 ch (3C 3L) [W] Theory and practice, topics include concepts of acid-base, redox, precipitation and solvent extraction equilibria; sample handling and preparation; calibration techniques; error analysis and regression analysis; titrimetric and spectrophotometric analysis. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisites: CHEM 1012 and 1017. CHEM 2201 Inorganic Chemistry I 3 ch (3C) Periodic properties of the atoms. Bonding, structures and reactions of inorganic compounds. Prerequisite: CHEM 1012. CHEM 2222 Inorganic Chemistry II 3 ch (3C) Bonding, structures and reactions of inorganic compounds. Prerequisite: CHEM 2201. CHEM 2237 Inorganic Chemistry Laboratory I 2 ch (3L) [W] Introduction to preparation techniques in inorganic chemistry. Applications of IR and UV-Vis spectroscopies. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisites: CHEM 1017, 2201, and 2416 Co-requisite: CHEM 2222. CHEM 2401 Introductory Organic Chemistry for Non-Chemistry Majors 3 ch (3C) An introductory course intended primarily for students requiring a one-term course in organic chemistry. This course emphasizes basic organic chemistry concepts such as the naming and structures of organic compounds, functional groups and chemical reactivity, and some basic chemistry relevant to biological processes. This course is not equivalent to CHEM 2421, and is designed to provide a broader coverage of material. Students in the Biology-Chemistry or Chemistry programs must take CHEM 2421. Credit cannot be obtained for both CHEM 2401 and CHEM 2421. Prerequisite: CHEM 1012 or 1982. CHEM 2416 Organic Chemistry Laboratory I 2 ch (3L) Introduction to experimental organic chemistry, with emphasis on laboratory techniques and structure determination. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 1017. Co-requisite: Either CHEM 2401 or 2421. CHEM 2421 Organic Chemistry I 3 ch (3C) An introductory course. Topics include: acids and bases in organic chemistry, stereochemistry and optical isomerism, functional groups and nomenclature, substitution and elimination reactions. This course is not equivalent to CHEM 2401; however, credit cannot be obtained for both CHEM 2401 and CHEM 2421. Prerequisite: CHEM 1012 or 1982. CHEM 2422 3|Page Organic Chemistry II 3 ch (3C) 2014-2015 Calendar Proof A continuation of CHEM 2421. Topics include: electrophilic addition to alkenes and their synthetic utility, aromaticity, electrophilic and nucleophilic aromatic substitution reactions, additions to the carbonyl group. Prerequisite: CHEM 2421. CHEM 2601 Physical Chemistry I 3 ch (3C) The three laws of thermodynamics, thermochemical calculations, chemical equilibria, introduction to phase rule. Prerequisites: MATH 1013 or equivalent and CHEM 1012; Corequisite: MATH 2003 or equivalent. CHEM 2903 Work Term Report I CR A written and oral report on the scientific activities of the work term. A component of the grade will be the employer’s evaluation of the student. (Students must have a GPA of 2.7 or better for CHEM CO-OP program.) CHEM 3003 Biocomputing in Drug Design I 5 ch (3C 3L) Introduction to biocomputing in the pharmaceutical industry. Topics include molecular modeling, rational drug design, high throughput screening and combinatorial chemistry, protein modeling and 3D bioinformatics. Course includes lectures and a computer laboratory component. Note: This course is also cross-listed as CS 3003 and may be taken for either Computer Science or Science credit. Prerequisites: CHEM 1001, 1012 and BIOL 1001, 1012, or permission of instructor. CHEM 2421 or BIOL 2033 are recommended. CHEM 3009 Experience in Chemistry Research II 3 ch (3L) [W] CHEM 3009 is a project based course where students conduct research under the supervision of a chosen faculty member. Students must have declared a Science Major and must have a CGPA of 3.7 or better to enter after first year or a CGPA of 3.0 or higher to enter after second year. Students will be provided with a list of projects and applicant’s names will be forwarded to project supervisors. Applications must be made to the Director of Undergraduate Studies by May 15. Project assignment will be made by the Director of Undergraduate Studies and enrolment may be limited. Students cannot be supervised by the same faculty member in CHEM 2009 and CHEM 3009. Students are encouraged to plan for alternative courses in the case that no suitable project is available. A minimum of at least 3 scheduled hours per week is required and one seminar presentation will be required at the end of the academic year, as well as a written report. WHMIS certification required (see beginning of Chemistry Courses section for details). Pre requisite: CHEM 1001, 1006, 1012, 1017, and 2009. CHEM 3122 Analytical Chemistry II 3 ch (3C) Principles of both equilibrium-based and basic instrumental methods of analysis. Topics include non-aqueous and complexometric titrations, analytical separations, potentiometry, analytical spectrophotometry, gas chromatography, elementary chemometrics, sample preparation and method development. Prerequisite: CHEM 2111. CHEM 3137 4|Page Analytical Chemistry Laboratory II 2 ch (3L) 2014-2015 Calendar Proof Applications of both equilibrium-based and basic instrumental methods of chemical analysis. Experiments are designed to illustrate the applications of non-aqueous and advanced titration methods, analytical separations, potentiometry, analytical spectrophotometry (atomic and UV-vis), liquid chromatography (HPLC), sampling and method development. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 2111. CHEM 3201 Inorganic Chemistry III 3 ch (3C) Selected aspects of main group inorganic chemistry emphasizing periodic trends. Prerequisite: CHEM 2222. CHEM 3222 Inorganic Chemistry IV 3 ch (3C) Covers transition metals and introduction to organometallic chemistry. Prerequisites: CHEM 2002 and 2222. CHEM 3236 Inorganic Chemistry Laboratory II 2 ch (3L)[W] Advanced preparative techniques in inorganic chemistry. Applications of IR and NMR spectroscopies. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 2237. CHEM 3421 Organic Chemistry III 3 ch (3C) Covers aldehydes, ketones, carboxylic acid derivatives, enolates, carbanion chemistry and organic synthesis. Prerequisite: CHEM 2422. CHEM 3422 Organic Chemistry IV 3 ch (3C) Selected topics in organic chemistry. Prerequisite: CHEM 2422. CHEM 3621 Physical Chemistry II 3 ch (3 C) Elementary electrochemistry, electrochemical cells, electrolysis, electromotive forces, applications of EMF measurements. Reaction kinetics and mechanisms, uni- bi-, and termolecular reactions, catalysis, enzyme catalysis, chain reactions, reaction dynamics, steric effects and transition state theory. Prerequisite: MATH 2003 or equivalent, CHEM 2601 (or CHE 2123 for Chemical Engineering students only). CHEM 3622 Physical Chemistry III 3 ch (3 C) Probability distributions, ensembles, Maxwell-Boltzman distribution, partition functions, hard sphere collision theory, potential energy surfaces, transition state theory, reaction dynamics. Prerequisites: Math 2003 and 2213 or equivalent, CHEM 2002 and 3621. CHEM 3637 Physical Chemistry Laboratory I 2 ch (3L) [W] Introduction to experimental physical chemistry. Topics include areas in thermochemistry, kinetics and electrochemistry. Some experiments have computational chemistry components. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 2002, 2601 and 3621. 5|Page 2014-2015 Calendar Proof CHEM 3857 Organic Chemistry Laboratory II for non-Chemistry majors 2 ch (3L) Advanced techniques and reactions in experimental organic chemistry, with an emphasis on synthetic techniques. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 2416; Co-requisite: CHEM 2422. Note: Credit can be obtained for only one of CHEM 3857 or CHEM 4416. CHEM 3886 Analytical Chemistry Laboratory for Chemical Engineers 2 ch (3L) This course teaches the basic techniques and data treatment in chemical analysis. The experimental content covers handling skills, titration methods and the applications of instrumental methods (UV - visible, and flame atomic absorption spectrophotmetry and potentiometry) to analyse real samples. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisites: CHEM 1982 and 1987. CHEM 3897 Organic Chemistry Laboratory for Chemical Engineers (*) 1 ch (3L) Introduction to experimental organic chemistry, with an emphasis on purification techniques. The synthesis of commercially valuable compounds will also be addressed. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisites: CHEM 1987 and 2401. CHEM 3903 Work Term Report II CR A written report on the scientific activities of the work term. A component of the grade will be the employer’s evaluation of the student. (Students must have a GPA of 2.7 or better for CHEM CO-OP program.) Prerequisite: Work Term Report I in a field of Science. CHEM 4000 Senior Research Projects 9 ch [W] CHEM 4000 is a project-based course where students conduct research under the supervision of a faculty member. Students must be in their final year of any Chemistry program or in any interdepartmental program involving Chemistry (including General Science) and must have a CGPA of 3.0 or better. Honours students in an interdepartmental program with chemistry may choose to complete their honours project in chemistry. A minimum of at least 6 scheduled hours per week is required throughout the year, and a thesis and seminar presentation will be required at the end of the academic year. Students must complete the application form, available from the CHEM 4000 coordinator, and submit it to the course coordinator no later than March 15 th of their penultimate year. Upon consideration by the Department, applicants will be notified on April 1st of that year. Enrollment is subject to project availability. Students who are unsuccessful in procuring a CHEM 4000 project are encouraged to pursue an Honours by Course option, and should meet with the DoUGS to discuss this option as soon as possible. WHMIS certification required (see beginning of Chemistry Courses section for details). Co-requisite: 4th year level lecture courses in selected project area. CHEM 4003 6|Page Biocomputing in Drug Design II 4 ch (3C 2L) 2014-2015 Calendar Proof A follow-up of CHEM 3003/CS 3003. Topics include pharmacophore perception, solvation models, free-energy calculations, quantitative structure activity relationship (QSAR), virtual drug libraries, chemical diversity and cheminformatics. Course includes lectures and computer laboratory component. Note: This course is cross-listed as CS 4003 and may be taken for either Computer Science or Science credit. Prerequisite: CHEM 3003 or CS 3003. CHEM 4013 Quantum Chemistry II 2 ch (2C) Applications of group theory in chemistry. Practical computational chemistry. Prerequisite: CHEM 2002. CHEM 4111 Instrumental Analytical Chemistry I 3 ch (2C 2L) A coordinated laboratory-lecture course to introduce the principles of instrumental analysis, operational aspects of analytical spectroscopy and chromatography. The laboratory component is designed to study the operation, application and limitation of selected methods which will form the basis of optimization and method development. Real materials are used to illustrate the common sample preparation methods. Students will use spreadsheet, word processor and program language extensively for data analysis and presentation. WHMIS certification required (see beginning of Chemistry Courses section for details) Prerequisites: CHEM 3122 and 3137. CHEM 4112 Advanced Analytical Chemistry 2 ch (2C) Advanced topics in analytical chemistry. Prerequisite: Departmental approval. CHEM 4222 Advanced Inorganic Chemistry 2 ch (2C) Advanced topics in inorganic chemistry. Prerequisite: Departmental approval. CHEM 4416 Organic Chemistry Laboratory II 2 ch (3L) Advanced techniques and reactions in experimental organic chemistry. Topics include functional group manipulation, carbon-carbon bond formation reactions, inert atmosphere techniques, and structure determination through spectroscopy. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 2416. Co-requisite: CHEM 3421. Note: Credit can be obtained for only one of CHEM 3857 or CHEM 4416. CHEM 4422 Advanced Organic Chemistry 2 ch (2C) Advanced topics in organic chemistry. Prerequisite: Departmental approval. CHEM 4513 Medicinal Chemistry Seminars 3 ch (3C) Selected Topics in Medicinal Chemistry. Prerequisite: CHEM 3421. CHEM 4523 Medicinal Chemistry 3 ch (3C) [W] An introduction to medicinal chemistry. Sample topics include the drug discovery process, the medicinal chemistry of enzymes, receptors, and nucleic acids, as well as modern experimental and computational approaches to drug design. Chemical aspects 7|Page 2014-2015 Calendar Proof of current protein and nucleic acids tools will also be covered. Prerequisites: BIOL 2033 and either CHEM 3421 or 3422. CHEM 4601 Physical Chemistry IV 3 ch (3C) Molecular Spectroscopy, electronic, vibrational and rotational spectra of diatomic and polyatomic molecules. Radiative and non-radiative transitions. Nuclear magnetic resonance and electron-spin resonance spectroscopy. Prerequisite: CHEM 2002. CHEM 4616 Physical Chemistry Laboratory II 2 ch (3L) [W] Experiments illustrating the fundamentals and applications of spectroscopy in the ultraviolet visible (UV-vis), infrared (IR) and radiofrequency (NMR) regions. Many experiments have computational chemistry components. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 3637. Corequisite: CHEM 4601. CHEM 4622 Advanced Physical Chemistry 2 ch (2C) Advanced topics in physical chemistry. Prerequisite: Departmental approval. CHEM 4886 Physical Chemistry Laboratory for Chemical Engineers 2 ch (3L) This course consists of experiments in chemical kinetics and electrochemistry. Topics include order of reaction, activation energies, reaction mechanisms, solution conductivities, enzyme kinetics and fast reaction kinetics. WHMIS certification required (see beginning of Chemistry Courses section for details). Prerequisite: CHEM 3621. CHEM 4903 Work Term Report III CR A written and oral report on the scientific activities of the work term. A component of the grade will be the employer’s evaluation of the student. (Students must have a GPA of 2.7 or better for CHEM CO-OP program.) Prerequisite: Work Term Report II in a field of Science. CHEM 4909 Directed Studies in Advanced Chemistry 3 ch Students may pursue directed studies in specific areas and topics related to chemistry. These studies may involve any of the chemistry disciplines. The content and process of each directed study will be determined through negotiation between a student and the supervising faculty member(s). Departmental approval is also required. CHEM 4919 Directed Studies in Advanced Chemistry 3 ch Students may pursue directed studies in specific areas and topics related to chemistry. These studies may involve any of the chemistry disciplines. The content and process of each directed study will be determined through negotiation between a student and the supervising faculty member(s). Departmental approval is also required. 8|Page