Kampo survey, Supplemental Data — 1 Supplemental Data This document presents additional information for Opinions on Kampo and reasons for using it – Results from a cross-sectional survey in three Japanese clinics Lydia Hottenbacher; Thorolf E.R. Weißhuhn; Kenji Watanabe; Takashi Seki; Julia Ostermann; Claudia M. Witt Table of Content Table 1: Current and recent diseases .................................................................................... 2 Table 2: Prevention and generally preferred treatment .......................................................... 3 Table 3: Preferred treatments for specified diseases/symptoms ............................................ 3 Table 4: Opinions about Kampo and Western medicine ......................................................... 7 Kampo survey, Supplemental Data — 2 Table 1: Current and recent diseases Disease Category All Kampo/CM % (n) % (n) Reason for Current Consultation (354 answering patients) Neurologic/Psychiatric * 21.2 (75) 29.1 (27) Cardiovascular 14.4 (51) 10.8 (10) Pain 14.1 (50) 23.7 (22) Allergy/Dermatological 11.9 (42) 8.6 (8) Gastroenterologic 11.6 (41) 8.6 (8) Metabolic 9.0 (32) 7.5 (7) Gynaecologic 7.3 (26) 7.5 (7) Pulmologic 6.5 (23) 5.4 (5) Hi’e-sho ** 5.6 (20) 3.2 (3) Cancer 3.1 (11) 3.2 (3) Rheumatologic 2.5 (9) 4.3 (4) Opthalmologic 2.0 (8) 7.5 (7) Nephrologic/Urologic 1.6 (7) 5.4 (5) Other 14.4 (51) 16.1 (15) Current Chronic Diseases (178 answering patients) Cardiovascular 11.3 (40) 7.5 (7) Neurologic/Psychiatric * 8.2 (29) 18.3 (17) Allergy/Dermatological 7.9 (28) 4.3 (4) Metabolic 6.5 (23) 7.5 (7) Gastroenterologic 6.5 (23) 7.5 (7) Pulmologic 5.1 (18) 4.3 (4) Pains 3.4 (12) 5.4 (5) Rheumatologic 3.4 (12) 3.2 (3) Gynaecologic 2.8 (10) 3.2 (3) Opthalmologic 2.8 (10) 7.5 (7) Nephrologic/Urologic 1.7 (6) 0.0 (0) Other 5.9 (21) 4.3 (4) Severe Diseases in the Last Five Years (76 answering patients) Gynaecologic 4.5 (16) 1.1 (1) Neurologic/Psychiatric * 3.1 (11) 8.6 (8) Gastroenterologic 2.8 (10) 6.4 (6) Cardiovascular 2.5 (9) 3.2 (3) Nephrologic/Urologic 2.5 (9) 2.2 (2) Pulmologic 2.0 (7) 3.2 (3) Opthalmologic 1.7 (6) 6.4 (6) Metabolic 1.4 (5) 2.2 (2) Rheumatologic 1.1 (4) 1.1 (1) Other 3.1 (11) 2.2 (2) History of Mental Disorder (40 answering patients) Any Disorder 11.3 (40) 3.2 (3) Integrative % (n) Kampo % (n) 18.4 (25) 22.8 (31) 6.6 (9) 10.3 (14) 5.1 (7) 16.2 (22) 3.7 (5) 9.6 (13) 0.7 (1) 0.7 (1) 0.0 (0) 0.0 (0) 0.0 (0) 11.8 (16) 18.4 (23) 8.0 (10) 15.2 (19) 16.0 ( 20) 20.8 (26) 2.4 (3) 11.2 (14) 11.2 (5) 12.8 (16) 5.6 (7) 4.0 (5) 0.8 (1) 1.6 (2) 16.0 (20) 16.9 (23) 1.5 (2) 5.8 (8) 7.4 (10) 2.9 (4) 6.6 (9) 3.7 (5) 0.7 (1) 1.5 (2) 0.7 (1) 0.7 (1) 2.2 (3) 8.0 (10) 8.0 (10) 12.8 (16) 4.8 (6) 9.6 (12) 4.0 (5) 1.6 (2) 6.4 (8) 4.0 (5) 1.6 (2) 4.0 (5) 11.2 (14) 0.7 (1) 0.0 (0) 0.7 (1) 2.9 (4) 1.5 (2) 2.2 (3) 0.0 (0) 2.2 (3) 0.0 (0) 1.5 (2) 11.2 (14) 2.4 (3) 2.4 (3) 1.6 (2) 4.0 (5) 0.8 (1) 0.0 (0) 0.0 (0) 2.4 (3) 5.6 (7) 16.2 (22) 12.0 (15) Multiple answers possible; percent of valid answers per clinic. CM (traditional) Chinese medicine. * Category includes very heterogeneous diagnoses such as vertigo, multiple sclerosis, or depression. ** Oversensitivity to cold syndrome, see text. Kampo survey, Supplemental Data — 3 Table 2: Prevention and generally preferred treatment Behaviour Prevention Strategies * Diet Exercise Sleep Stress Reduction Other ** Generally Preferred Treatment Western + Kampo Western Kampo All % (n) Kampo/CM % (n) Integrative % (n) Kampo % (n) 37.3 (132) 33.3 (118) 12.4 (44) 5.4 (19) 21.5 (76) 38.7 (36) 33.3 (31) 8.6 (8) 5.4 (5) 14.0 (13) 26.5 (36) 27.2 (37) 7.4 (10) 2.9 (4) 19.1 (26) 40.0 (60) 48.0 (50) 20.8 (26) 8.0 (10) 29.6 (37) 54.4 (179) 31.3 (103) 14.3 (47) 52.2 (47) 27.8 (25) 20.0 (18) 54.7 (64) 37.6 (44) 7.7 (9) 55.7 (68) 27.9 (34) 16.4 (20) Percent of valid answers per clinic. * Multiple answers possible. ** Includes a frequently stated healthy lifestyle, and hygienic measures such as washing hands, or gargling (a Japanese custom to avoid diseases: rinsing out dust and dirt upon returning home). CM (traditional) Chinese medicine. “Western” = “conventional” Western biomedicine. Table 3: Preferred treatments for specified diseases/symptoms Ailment All Kampo/CM % (n) % (n) Addiction (Tobacco, Alcohol, Drugs) Western 9.1 (28) 7.1 (6) Kampo 10.1 (31) 5.9 (5) Both Combined 30.5 (94) 34.1 (29) Don’t Know 50.3 (155) 52.9 (45) Allergy Western 6.8 (21) 4.8 (4) Kampo 34.7 (108) 37.3 (31) Both Combined 38.6 (120) 34.9 (29) Don’t Know 19.9 (62) 22.9 (19) Anaemia Western 12.0 (37) 11.9 (10) Kampo 22.7 (70) 21.4 (18) Both Combined 32.8 (101) 33.3 (28) Don’t Know 32.5(100) 33.3 (28) Asthma Western 14.0 (44) 10.6 (9) Kampo 13.7 (43) 15.3 (13) Both Combined 43.6 (137) 43.5 (37) Don’t Know 28.7 (90) 30.6 (26) Bronchitis Western 17.6 (55) 11.8 (10) Kampo 12.5 (39) 16.5 (14) Both Combined 41.5 (130) 42.4 (36) Don’t Know 28.4 (89) 29.4 (25) Integrative % (n) Kampo % (n) 10.2 (12) 7.6 (9) 27.1 (32) 55.1 (65) 9.5 (10) 16.2 (17) 31.4 (33) 42.9 (45) 10.0 (12) 29.2 (35) 39.2 (47) 21.7 (26) 4.6 (5) 38.9 (42) 40.7 (44) 15.7 (17) 13.7 (16) 17.1 (20) 33.3 (39) 35.9 (42) 10.3 (11) 29.9 (32) 31.8 (34) 28.0 (30) 15.7 (19) 11.6 (14) 43.8 (53) 28.9 (35) 14.8 (16) 14.8 (16) 43.5 (47) 26.9 (29) 24.4 (29) 8.4 (10) 37.0 (44) 30.3 (36) 14.7 (16) 13.8 (15) 45.9 (50) 25.7 (28) Kampo survey, Supplemental Data — 4 Ailment All % (n) Cancer (Any Kind) Western 26.7 (83) Kampo 1.9 (6) Both Combined 40.2 (125) Don’t Know 31.2 (97) Colds Western 18.8 (59) Kampo 19.8 (62) Both Combined 45.0 (141) Don’t Know 16.3 (51) Cystitis Western 19.9 (63) Kampo 12.3 (39) Both Combined 30.9 (98) Don’t Know 36.9 (117) Depression Western 7.3 (23) Kampo 15.0 (47) Both Combined 42.5 (133) Don’t Know 35.1 (110) Diabetes Western 17.1 (54) Kampo 10.8 (34) Both Combined 37.8 (119) Don’t Know 34.3 (108) Digestive Disorders Western 5.1 (16) Kampo 36.4 (115) Both Combined 39.2 (124) Don’t Know 19.3 (61) Disturbed Sleep Western 6.3 (20) Kampo 30.7 (97) Both Combined 36.7 (116) Don’t Know 26.3 (83) Gastric Ulcers Western 21.5 (66) Kampo 9.4 (29) Both Combined 37.8 (116) Don’t Know 31.3 (96) Gynaecological Problems Western 6.7 (21) Kampo 27.5 (86) Both Combined 37.1 (116) Don’t Know 28.8 (90) Hay Fever Western 6.6 (21) Kampo 31.6 (100) Both Combined 39.6 (125) Don’t Know 22.2 (70) Kampo/CM % (n) Integrative % (n) Kampo % (n) 27.9 (24) 2.3 (2) 39.5 (34) 30.2 (26) 28.0 (33) 1.7 (2) 35.6 (42) 34.7 (41) 24.3 (26) 1.9 (2) 45.8 (49) 28.0 (30) 11.8 (10) 22.4 (19) 45.9 (39) 20.0 (17) 22.7 (27) 14.3 (17) 42.0 (50) 21.0 (25) 20.2 (22) 23.9 (26) 47.7 (52) 8.3 (9) 16.3 (14) 14.0 (12) 32.6 (28) 37.2 (32) 25.0 (30) 10.0 (12) 28.3 (34) 36.7 (44) 17.1 (19) 13.5 (15) 32.4 (36) 36.9 (41) 5.9 (5) 12.9 (11) 42.4 (36) 38.8 (33) 9.2 (11) 13.3 (16) 37.5 (45) 40.0 (48) 6.5 (7) 18.5 (20) 48.1 (52) 26.9 (29) 19.5 (17) 11.5 (10) 34.5 (30) 34.5 (30) 18.5 (22) 8.4 (10) 37.0 (44) 36.1 (43) 13.8 (15) 12.8 (14) 41.3 (45) 32.1 (35) 3.5 (3) 30.2 (26) 43.0 (37) 23.3 (20) 8.3 (10) 30.0 (36) 37.5 (45) 24.2 (29) 2.7 (3) 48.2 (53) 38.2 (42) 10.9 (12) 3.5 (3) 33.7 (29) 33.7 (29) 29.1 (25) 7.5 (9) 25.8 (31) 38.3 (46) 28.3 (34) 7.3 (8) 33.6 (37) 37.3 (41) 21.8 (24) 22.9 (19) 10.8 (9) 38.6 (32) 27.7 (23) 26.3 (31) 6.8 (8) 33.1 (39) 33.9 (40) 15.1 (16) 11.3 (12) 42.5 (45) 31.1 (33) 8.3 (7) 28.6 (24) 33.3 (28) 29.8 (25) 10.0 (12) 25.0 (30) 32.5 (39) 32.5 (39) 1.8 (2) 29.4 (32) 45.0 (49) 23.9 (26) 4.8 (4) 32.1 (27) 35.7 (30) 27.4 (23) 9.1 (11) 29.8 (36) 37.2 (45) 24.0 (29) 5.4 (6) 33.3 (37) 45.0 (50) 16.2 (18) Kampo survey, Supplemental Data — 5 Ailment All % (n) Hi’e-sho * Western 1.6 (5) Kampo 64.0 (203) Both Combined 18.3 (58) Don’t Know 15.8 (50) High Blood pressure Western 17.4 (55) Kampo 17.1 (54) Both Combined 34.2 (108) Don’t Know 31.3 (99) Kidney Disorders Western 16.8 (52) Kampo 10.4 (32) Both Combined 37.5 (116) Don’t Know 35.3 (109) Low Back Pain Western 7.9 (25) Kampo 25.2 (80) Both Combined 38.5 (122) Don’t Know 28.4 (90) Low Blood pressure Western 12.5 (39) Kampo 22.7 (71) Both Combined 31.0 (97) Don’t Know 33.9 (106) Migraine/Headache Western 14.0 (44) Kampo 22.9 (72) Both Combined 34.4 (108) Don’t Know 28.7 (90) Muscular Problem/Disease Western 8.3 (26) Kampo 18.8 (59) Both Combined 37.3 (117) Don’t Know 35.7 (112) Neuralgia Western 7.4 (23) Kampo 24.3 (75) Both Combined 34.3 (106) Don’t Know 34.0 (105) Obesity Western 3.2 (10) Kampo 29.6 (92) Both Combined 28.3 (88) Don’t Know 38.9 (121) Pneumonia Western 37.1 (116) Kampo 4.5 (14) Both Combined 28.1 (88) Don’t Know 30.4 (95) Kampo/CM % (n) Integrative % (n) Kampo % (n) 0.0 (0) 67.1 (57) 18.8 (16) 14.1 (12) 3.4 (4) 51.7 (61) 18.6 (22) 26.3 (31) 0.9 (1) 75.2 (85) 17.7 (20) 6.2 (7) 17.2 (15) 18.4 (16) 31.0 (27) 33.3 (29) 20.8 (25) 13.3 (16) 32.5 (39) 33.3 (40) 13.8 (15) 20.2 (22) 38.5 (42) 27.5 (30) 15.5 (13) 13.1 (11) 34.5 (29) 36.9 (31) 21.7 (25) 6.1 (7) 34.8 (40) 37.4 (43) 12.7 (14) 12.7 (14) 42.7 (47) 31.8 (35) 5.9 (5) 29.4 (25) 40.0 (34) 24.7 (21) 11.0 (13) 16.1 (19) 37.3 (44) 35.6 (42) 6.1 (7) 31. (36) 38.6 (44) 23.7 (27) 12.9 (11) 20.0 (17) 32.9 (28) 34.1 (29) 17.6 (21) 17.6 (21) 29.4 (35) 35.3 (42) 6.4 (7) 30.3 (33) 31.2 (34) 32.1 (35) 4.7 (4) 30.2 (26) 37.2 (32) 27.9 (24) 17.6 (21) 15.1 (18) 31.1 (37) 36.1 (43) 17.4 (19) 25.7 (28) 35.8 (39) 21.1 (23) 2.3 (2) 20.9 (18) 46.5 (40) 30.2 (26) 13.4 (16) 12.6 (15) 31.9 (38) 42.0 (50) 7.3 (8) 23.9 (26) 35.8 (39) 33.0 (36) 2.3 (2) 33.7 (29) 37.2 (32) 26.7 (23) 11.1 (13) 15.4 (18) 31.6 (37) 41.9 (49) 7.5 (8) 26.4 (28) 34.9 (37) 31.1 (33) 4.7 (4) 25.9 (22) 28.2 (24) 41.2 (35) 3.3 (4) 29.2 (35) 29.2 (35) 38.3 (46) 1.9 (2) 33.0 (35) 27.4 (29) 37.7 (40) 34.1 (29) 4.7 (4) 25.9 (22) 35.3 (30) 39.5 (47) 3.4 (4) 26.1 (31) 31.1 (37) 36.7 (40) 5.5 (6) 32.1 (35) 25.7 (28) Kampo survey, Supplemental Data — 6 Ailment All % (n) Rheumatism Western 7.4 (23) Kampo 18.6 (58) Both Combined 35.6 (111) Don’t Know 38.5 (120) Shoulder Stiffness Western 3.4 (11) Kampo 42.1 (136) Both Combined 29.1 (94) Don’t Know 25.4 (82) Skin Disorders Western 13.2 (41) Kampo 21.9 (68) Both Combined 39.2 (122) Don’t Know 25.7 (80) Stress/Anxiety Western 2.2 (7) Kampo 34.1 (109) Both Combined 42.5 (136) Don’t Know 21.3 (68) Kampo/CM % (n) Integrative % (n) Kampo % (n) 4.8 (4) 16.7 (14) 42.9 (36) 35.7 (30) 9.3 (11) 17.8 (21) 30.5 (36) 42.4 (50) 7.3 (8) 20.9 (23) 35.5 (39) 36.4 (40) 2.4 (2) 45.9 (39) 30.6 (26) 21.2 (18) 6.6 (8) 33.6 (41) 27.9 (34) 32.0 (39) 0.9 (1) 48.3 (56) 29.3 (34) 21.6 (25) 14.3 (12) 16.7 (14) 41.7 (35) 27.4 (23) 16.9 (20) 20.3 (24) 33.1 (39) 29.7 (35) 5.4 (9) 33.3 (30) 45.0 (48) 16.2 (22) 0.0 (0) 34.5 (30) 43.7 (38) 21.8 (19) 5.0 (6) 27.3 (33) 39.7 (48) 28.1 (34) 0.9 (1) 41.1 (46) 44.6 (50) 13.4 (15) Percent of valid answers per clinic. CM (traditional) Chinese medicine. ”Western” = “conventional” Western biomedicine. * Oversensitivity to cold syndrome, see text. Kampo survey, Supplemental Data — 7 Table 4: Opinions about Kampo and Western medicine Statement It is important to perceive the whole patient Diseases are the result of the body being out of balance Kampo will probably spread further in the future Kampo activates self-regulating forces Kampo is a more natural form of healing than Western medicine Kampo herbs in food are good for the body Kampo perceives the whole patient I think Kampo is effective I think Western medicine is effective Western medicine drugs have unfavourable side effects I am satisfied with Kampo The concept of Yin and Yang is true * The concept of Wu Xing (Five Phases) is true * Doctors practicing Western medicine do not take enough time for their patients Kampo is rooted in Japan and therefore suitable for treating Japanese The philosophy of Kampo is totally different from Western medicine I am satisfied with Western medicine Doctors practicing Western medicine do not listen well to their patients Doctors practicing Western medicine are difficult to talk to Appointments at a Kampo outpatient clinic are easier to obtain Kampo drugs do not have any side effects Kampo has an effect on certain diseases only It is very unpleasant to take Kampo drugs Kampo is old-fashioned All Mean±SD (Median) 4.46±0.87 (5) 4.43±0.72 (5) 4.13±0.83 (4) 4.09±0.84 (4) 4.09±0.77 (4) 3.99±0.78 (4) 3.96±0.93 (4) 3.88±0.77 (4) 3.83±0.82 (4) 3.78±0.87 (4) 3.77±0.83 (4) 3.61±0.90 (4) 3.54±0.97 (3) 3.39±0.89 (3) 3.38±1.08 (3) 3.33±0.89 (3) 3.31±0.84 (3) 3.09±1.08 (3) 3.08±1.01 (3) 2.96±0.82 (3) 2.74±0.97 (3) 2.71±1.05 (3) 2.07±1.12 (2) 1.86±1.02 (2) Kampo/CM Mean±SD (Median) 4.55±0.86 (5) 4.49±0.71 (5) 4.30±0.85 (5) 4.25±0.96 (4) 4.14±0.81 (4) 4.01±0.89 (4) 4.24±0.87 (4) 3.98±0.72 (4) 3.83±0.79 (4) 3.76±0.79 (4) 3.91±0.83 (4) 3.64±0.87 (4) 3.59±0.87 (3) 3.21±0.98 (3) 3.44±1.10 (3) 3.34±0.92 (3) 3.26±0.91 (3) 3.00±1.23 (3) 2.98±0.98 (3) 2.90±0.95 (3) 2.85±0.94 (3) 2.70±1.30 (3) 2.17±1.24 (2) 1.90±1.15 (1) Integrative Mean±SD (Median) 4.24±0.98 (5) 4.24±0.77 (4) 3.76±0.72 (4) 3.69±0.76 (4) 3.90±0.73 (4) 3.88±0.76 (4) 3.48±0.79 (3) 3.65±0.72 (4) 3.69±0.82 (4) 3.64±0.83 (4) 3.52±0.73 (3) 3.47±0.86 (3) 3.41±1.12 (3) 3.37±0.83 (3) 3.22±0.87 (3) 3.28±0.72 (3) 3.39±0.75 (3) 2.88±0.98 (3) 2.96±1.00 (3) 3.01±0.47 (3) 2.94±0.88 (3) 2.86±0.82 (3) 2.20±1.06 (2) 2.05±0.93 (2) Kampo Mean±SD (Median) 4.63±0.71 (5) 4.59±0.61 (5) 4.37±0.80 (5) 4.39±0.65 (4) 4.24±0.76 (4) 4.09±0.70 (4) 4.25±0.90 (4) 4.05±0.79 (4) 3.98±0.82 (4) 3.93±0.93 (4) 3.92±0.88 (4) 3.69±0.94 (4) 3.58±0.97 (3) 3.53±0.87 (3) 3.50±1.23 (4) 3.36±1.01 (3) 3.25±0.87 (3) 3.36±1.01 (3) 3.27±1.02 (3) 2.96±0.97 (3) 2.46±1.02 (3) 2.57±1.05 (3) 1.87±1.06 (1.5) 1.65±0.97 (1) Answers on 5 point Likert item, 1 = “I fully disagree”, 5 = “I fully agree”. SD standard deviation. CM (traditional) Chinese medicine. “Western medicine” = “conventional” Western biomedicine. * Only patients who knew about concept.